scholarly journals Contact Screening and Isoniazid Preventive Therapy Initiation for Under-Five Children among Pulmonary Tuberculosis-Positive Patients in Bahir Dar Special Zone, Northwest Ethiopia: A Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Netsanet Fentahun ◽  
Yosef Wasihun ◽  
Abebe Mamo ◽  
Lakew Abebe Gebretsadik
Keyword(s):  
Pulmonary Tuberculosis ◽  
Preventive Therapy ◽  
Northwest Ethiopia ◽  
Isoniazid Preventive Therapy ◽  
Bahir Dar ◽  
Cross Sectional ◽  
Under Five ◽  
Under Five Children ◽  
Therapy Initiation ◽  
Contact Screening

Background. Children are highly susceptible to Mycobacterium tuberculosis infection, and about 70% of children living in the same households with pulmonary tuberculosis-positive patients will become infected. However, pulmonary positive tuberculosis is a common phenomenon and the implementation of the recommended contact screening and initiation of isoniazid preventive therapy is very low. Therefore, this study is aimed at assessing contact screening practice and initiation of isoniazid preventive therapy of under-five children among pulmonary tuberculosis-positive patients in Bahir Dar, northwest Ethiopia. Methods. A facility-based cross-sectional study was conducted from March 1 to 30, 2016. A total of 267 pulmonary tuberculosis-positive patients were included in this study. To identify independent predictors of contact screening and isoniazid preventive therapy initiation, we performed multivariable logistic regression analyses using SPSS version 20 with CI of 95% at p value < 0.05. Results. A total of 230 (90.2%) pulmonary tuberculosis-positive patients had single contacts with their under-five children. One hundred nine (64.8%) children were screened. From those screened, 11 (7.4%) developed tuberculosis disease and started antituberculosis treatment. Forty-four (31.9%) children started isoniazid preventive therapy. Sex of the participants, place of service delivery, relationship with contacts, HIV status, and attitude of PTB+ cases were significant predictors of contact screening (p<.05). Participant’s knowledge, attitude of participants, and relationship of the child with participant were significant predictors of isoniazid preventive therapy initiation (p<0.05). Conclusion. Contact screening practice and isoniazid preventive therapy initiation of children under the age of 5 in Bahir Dar zone were very low. Intimate family contact with pulmonary tuberculosis-positive patients, place of service delivery, and attitude towards screening are the key factors of contact screening. Participant’s knowledge, attitude of participants, and relationship of the child with participant are the key factors of isoniazid preventive therapy initiation. Therefore, household contact screening and isoniazid preventive therapy initiation should be paid attention to reduce transmission.

scholarly journals Active household contact screening for tuberculosis and provision of isoniazid preventive therapy to under-five children in Afghanistan

PLoS ONE ◽  
2020 ◽  
Vol 15 (10) ◽  
pp. e0240031 ◽  
Author(s):  
Said Mirza Sayedi ◽  
Mohammad Khaled Seddiq ◽  
Mohammad K. Rashidi ◽  
Ghulam Qader ◽  
Naser Ikram ◽  
...  
Keyword(s):  
Preventive Therapy ◽  
Household Contact ◽  
Isoniazid Preventive Therapy ◽  
Under Five ◽  
Under Five Children ◽  
Contact Screening

scholarly journals Socioeconomic Predictors of Intestinal Parasitic Infections Among Under-Five Children in Rural Dembiya, Northwest Ethiopia: A Community-Based Cross-sectional Study

2019 ◽  
Vol 13 ◽  
pp. 117863021989680
Author(s):  
Zemichael Gizaw ◽  
Ayenew Addisu ◽  
Mulat Gebrehiwot
Keyword(s):  
Parasitic Infection ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
Parasitic Infections ◽  
Intestinal Parasitic Infection ◽  
Cross Sectional ◽  
Intestinal Parasitic Infections ◽  
Under Five ◽  
Under Five Children ◽  
Health Supervision

Background: Soil-transmitted helminths and protozoan parasitic infections are endemic throughout the world. The problem of intestinal parasitic infection is higher among developing countries where children are the most vulnerable groups. Although health information related to parasitic infections is available globally, it is often limited in rural setups in least developed countries. This study was, therefore, conducted to assess socioeconomic predictors of intestinal parasitic infections among under-five children in rural Dembiya, Northwest Ethiopia. Methods: This cross-sectional study was conducted among 224 randomly selected households with under-five children. We used questionnaire to collect data and direct stool examination to identify intestinal parasitic infections. Adjusted odds ratio (AOR) with 95% confidence interval (CI) and P < .05 was used to identify socioeconomic predictors of parasitic infections. Results: We found that 25.4% (95% CI = [20.2, 31.1]) under-five children had intestinal parasitic infection. Ascaris lumbricoides was the leading infection, which accounted 44 of 224 (19.6%). The prevalence of childhood intestinal parasitic infections was higher among households with no members whose education level is secondary and above (AOR = 3.36, 95% CI = [1.23, 9.17]). Similarly, intestinal parasitic infections were statistically associated with presence of 2 under-five children in a household (AOR = 3.56, 95% CI = [1.29, 9.82]), absence of frequent health supervision (AOR = 3.49, 95% CI = [1.72, 7.09]), larger family size (AOR = 2.30, 95% CI = [1.09, 4.85]), and poor household economic status (AOR = 2.58, 95% CI = [1.23, 5.41]). Conclusions: Significant proportion of children was infected with intestinal parasitic infection in rural Dembiya. Educational status of family members, number of under-five children in a household, health supervision, family size, and wealth index were statistically associated with parasitic infections. Provision of anthelmintic drugs, health supervision, and health education targeted with transmission and prevention of infections are recommended.

scholarly journals Diarrhea Prevention Practice and Associated Factors among Caregivers of Under-Five Children in Enemay District, Northwest Ethiopia

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Melese Dubie Agegnehu ◽  
Liknaw Bewket Zeleke ◽  
Yitayal Ayalew Goshu ◽  
Yonas Lamore Ortibo ◽  
Yohannes Mehretie Adinew
Keyword(s):  
Family Size ◽  
Associated Factors ◽  
Diarrheal Disease ◽  
Good Practice ◽  
Multivariable Analysis ◽  
Sampling Technique ◽  
Northwest Ethiopia ◽  
Cross Sectional ◽  
Under Five ◽  
Under Five Children

Background. Diarrhea is the leading cause of mortality among infants and children younger than 5 years of age in both underdeveloped and developing countries. Factors determining the occurrence of diarrhea in children are complex, and the relative contribution of each factor varies as a function of interaction between socioeconomic, environmental, and behavioral variables. Objectives. To assess diarrhea prevention practice and associated factors of diarrheal disease among caregivers who have under-five children in Enemay district, Ethiopia, 2018. Methods. Community-based cross-sectional study was done from June 1–30, 2018, among 398 caregivers who have under-five children, in the Enemay district that were selected by using the simple random sampling technique. A structured and pretested data collection tool was used to collect the data. Data were entered using EPI DATA version 4.2, and analysis was done using SPSS version 20 statistical package to be cleaned and analyzed. Descriptive analysis was done to describe study participants, and logistic regression (bivariable and multivariable) analysis was done to identify factors that have association with the dependent variable. The P value was less than 0.05. Results. A total of 398 with a response rate of 97% under-five caregivers were participated in this study. Nearly, half (48.7%) of the participants were in the age group 25–34. The study revealed that good practice of diarrhea prevention was 52.8%. This study was also identified that occupation (AOR: 3.922, 95% CI: 1.593, 9.657), family size (AOR: 0.088, 95% CI: 0.009, 0.916), and understanding on diarrhea (AOR: 0.237, 95% CI: 0.091, 0.613) were associated factors of diarrhea prevention practice of under-five children caregivers. Conclusion. This finding showed that diarrhea prevention practice among under-five children caregivers was low and prevention practice was significantly associated with caregivers’ awareness on frequency of diarrhea in a day, occupation, and family size in a house.

scholarly journals Diarrhea Prevalence and Associated Factors Among Under-Five Children in the Periphery Area of Azezo Sub-City, Gondar, Northwest Ethiopia: A community Based Cross-Sectional Study

2021 ◽  
Author(s):  
Bikes Destaw Bitew ◽  
Atalay Getachew ◽  
Jember Azanaw
Keyword(s):  
Associated Factors ◽  
Diarrheal Disease ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
Age Group ◽  
Monthly Income ◽  
Community Based ◽  
Cross Sectional ◽  
Under Five ◽  
Under Five Children

Abstract Background Although there has been a global decrease in childhood diarrheal disease in parallel with improvements in the standard of living, it still remains a significant public health problem that occurs due to poor WASH status and other related factors that cause massive childhood morbidity and mortality particularly in sub-Saharan Africa countries including Ethiopia. Objective To assess diarrheal disease prevalence and associated factors among under-five children in periphery area of Azezo sub-city, Gondar, northwest Ethiopia. Methods A community-based cross-sectional study was conducted in April 2019. A simple random sampling technique was applied to recruit the eligible clusters/villages. Structured interview questionnaires were used to collect data. The completed data were entered into Epi Info version 7 and exported to SPSS version 20 for further analysis. A binary logistic regression model was used to process bivariate and multivariable analysis of the data to establish the association between dependent and independent variables. The adjusted odds ratio (AOR) with 95% CI was used for the interpretation of data after controlling the confounders. Results The two-week prevalence of U5C diarrheal disease was 24.9% with 95% CI: (20.4 – 29.7). Age group of 1-12months [AOR: 9.22, 95%CI: (2.93-29.04)], age group of 13-24months [AOR: 4.44, 95%CI: (1.87-10.56)], low monthly income (AOR: 3.68, 95% CI: (1.81-7.51)], small family size [AOR: 0.32, 95% CI: (0.16-0.65)], poor hand washing practice [AOR: 8.37, 95% CI: (3.12-22.52), and immediate feed for cooked foods [AOR: 0.39, 95%CI: (0.19-0.81)] were significantly associated factors with childhood diarrhea. Conclusion Diarrhea was a common health problem among under-five children in the periphery area of Azezo sub-city. Age of children, family size, monthly income, hand-washing practice, and feeding time for cooked food were identified statistically significant risk factors. Therefore, an appropriate intervention program through health education would be recommended with a focus on identified risk factors to reduce the burden of diarrheal diseases.

scholarly journals Campylobacter Jejuni and Its Antimicrobial Susceptibility Pattern Among Under- Five Children with Gastroenteritis in Northwest Ethiopia

2021 ◽  
Author(s):  
Bukayaw wudie ◽  
Addisu Melese ◽  
Daniel Mekonnen
Keyword(s):  
Campylobacter Jejuni ◽  
Acute Gastroenteritis ◽  
Diarrheal Disease ◽  
Demographic Data ◽  
Epidemiological Data ◽  
Drug Susceptibility ◽  
Northwest Ethiopia ◽  
Cross Sectional ◽  
Under Five ◽  
Under Five Children

Abstract Introduction: Campylobacter jejuni is the leading causes of diarrheal disease worldwide among under five years of age. Epidemiological data about C. jejuni and drug susceptibility profile of isolates among children with symptom of gastroenteritis has a paramount importance for evidence based decision. However, such information is not available in the study area. Hence, this study was carried out fill this information gap.Methods: An institution based cross-sectional study was conducted among under-five children (U5C) visiting four primary health centers’ pediatric clinic due to acute gastroenteritis from February to May, 2019. Socio-demographic data were collected in a face to face interview using structured questionnaire. Stool specimen was collected and transported to the Bahir Dar University, Medical Microbiology Laboratory. The specimens were inoculated on Charcoal Cefoperazone Deoxycholate Agar. Identification and antibacterial susceptibility test was performed using standard bacteriological methods. The collected data were entered to EpiData 3.1 and analyzed using SPSS version 23.Results: Among a total of 196 U5C with acute gastroenteritis, 39 (19.9%) were positive for Campylobacter species. The proportion of C. jejuni was 14.8% (29/196). The multivariate logistic regression analyses revealed that care givers (AOR=3.76, 95%CI: 1.29-10.98), guardians hand washing practice before food preparation (AOR=3.63, 95%CI: 1.15-11.46), and contact with domestic animals (AOR=4.23, 95%CI: 1.46-12.28) demonstrated significant association with C. jejuni infection. Among 29 C. jejuni isolates, 24 (82.8%), 24 (82.8%) and 18 (62.1%) were resistant for tetracycline, cefoxitine and erythromycin, respectively. Conclusions: The proportion of C. jejuni infection was high. Children who had contact with animals showed association with C. jejuni infection. Additionally, majority of C. jejuni showed resistance for tetracycline, cefoxitin, ampicillin and erythromycin.

scholarly journals Water, Sanitation, and Hygiene Risk Factors on the Prevalence of Diarrhea among Under-Five Children in the Rural Community of Dangila District, Northwest Ethiopia

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Bizuayehu Hailu ◽  
Wu Ji-Guo ◽  
Tadesse Hailu
Keyword(s):  
Rural Community ◽  
Statistical Significance ◽  
Northwest Ethiopia ◽  
Morbidity And Mortality ◽  
Clean Water ◽  
Cross Sectional ◽  
Mortality And Morbidity ◽  
Under Five ◽  
Under Five Children ◽  
Sanitation And Hygiene

Background. Under-five diarrhea is one of the major causes of morbidity and mortality in developing countries. Despite the tremendous achievement in reducing child mortality and morbidity in the last two decades, diarrhea is still the major causes of morbidity and mortality in resource-limited countries like Ethiopia due to the absence of clean water and poor sanitation and hygiene. Objective. This study aimed to assess the association of water, sanitation, and hygiene on the prevalence of diarrhea among under-five children in the rural community of Ethiopia. Methods. A cross-sectional study was conducted among randomly selected 419 under-five children from October to December 2021 in Dangila district, Northwest Ethiopia. A structured questionnaire was used to collect sociodemographic, environmental, and behavioral data. Data were entered into Epi Info and analyzed using SPSS software. Descriptive analysis was used to calculate the prevalence of diarrhea. Univariate and multivariate logistic regression were used to compute the association of water, sanitation, and hygiene with diarrhea. Statistical significance was considered if P < 0.05 . Results. Among 419 participants, the prevalence of diarrhea was 106 (25.3%). The absence of handwashing habit of children (AOR = 7.70; 95% CI: 2.71–21.79) and caregivers after toilet (AOR = 19.10; 95% CI: 5.46–66.52), absence of latrine (AOR = 3.87; 95% CI: 1.24–12.08), playing with soil (AOR = 8.40; 95% CI: 4.58–36.66), and eating soil (AOR = 6.24; 95% CI: 1.99–19.78) were significantly associated with under-five diarrhea. Children who drink unprotected water were 2.21 times (AOR = 2.21; 95% CI: 0.51–9.69) more exposed to under-five diarrhea than who drink protected water, but it is not statistically significant ( P = 0.29 ). Conclusion. The prevalence of under-five diarrhea is high in Dangila district. The absence of clean water and poor handwashing practice and the absence of latrine are the main factors associated with diarrhea. Therefore, strengthening water, sanitation, and hygiene strategy in the rural community should be prioritized.

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