scholarly journals Functional Glycopolypeptides: Synthesis and Biomedical Applications

2020 ◽  
Vol 2020 ◽  
pp. 1-16
Author(s):  
Zhao Wang ◽  
Xiaojuan Zhang ◽  
Qing Lin ◽  
Jingjing Sun ◽  
Santanu Bhattachaya ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cell Culture ◽  
Cell Adhesion ◽  
Gene Delivery ◽  
Green Chemistry ◽  
Biomedical Applications ◽  
Biomolecular Recognition ◽  
Biological Applications ◽  
Future Outlook

Employing natural-based renewable sugar and saccharide resources to construct functional biopolymer mimics is a promising research frontier for green chemistry and sustainable biotechnology. As the mimics/analogues of natural glycoproteins, synthetic glycopolypeptides attracted great attention in the field of biomaterials and nanobiotechnology. This review describes the synthetic strategies and methods of glycopolypeptides and their analogues, the functional self-assemblies of the synthesized glycopolypeptides, and their biological applications such as biomolecular recognition, drug/gene delivery, and cell adhesion and targeting, as well as cell culture and tissue engineering. Future outlook of the synthetic glycopolypeptides was also discussed.

Fluoropolymers in biomedical applications: state-of-the-art and future perspectives

2021 ◽  
Author(s):  
Jia Lv ◽  
Yiyun Cheng
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Cell Culture ◽  
Gene Delivery ◽  
Bacterial Cell ◽  
Protein Delivery ◽  
Biomedical Applications ◽  
State Of The Art ◽  
Future Perspectives

Biomedical applications of fluoropolymers in gene delivery, protein delivery, drug delivery, 19F MRI, PDT, anti-fouling, anti-bacterial, cell culture, and tissue engineering.

Graphene and Graphene-Based Materials in Biomedical Applications

2019 ◽  
Vol 26 (38) ◽  
pp. 6834-6850 ◽  
Author(s):  
Mohammad Omaish Ansari ◽  
Kalamegam Gauthaman ◽  
Abdurahman Essa ◽  
Sidi A. Bencherif ◽  
Adnan Memic
Keyword(s):  
Tissue Engineering ◽  
Thermal Properties ◽  
Gene Delivery ◽  
Regenerative Medicine ◽  
Biomedical Research ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Two Dimensional ◽  
Drug And Gene Delivery ◽  
Biomedical Fields

: Nanobiotechnology has huge potential in the field of regenerative medicine. One of the main drivers has been the development of novel nanomaterials. One developing class of materials is graphene and its derivatives recognized for their novel properties present on the nanoscale. In particular, graphene and graphene-based nanomaterials have been shown to have excellent electrical, mechanical, optical and thermal properties. Due to these unique properties coupled with the ability to tune their biocompatibility, these nanomaterials have been propelled for various applications. Most recently, these two-dimensional nanomaterials have been widely recognized for their utility in biomedical research. In this review, a brief overview of the strategies to synthesize graphene and its derivatives are discussed. Next, the biocompatibility profile of these nanomaterials as a precursor to their biomedical application is reviewed. Finally, recent applications of graphene-based nanomaterials in various biomedical fields including tissue engineering, drug and gene delivery, biosensing and bioimaging as well as other biorelated studies are highlighted.

scholarly journals In silico study of PEI-PEG-squalene-dsDNA polyplex formation: The delicate role of PEG length to the binding of PEI to DNA

2021 ◽  
Author(s):  
Tudor Vasiliu ◽  
Bogdan Florin Florin Craciun ◽  
Andrei Neamtu ◽  
Lilia Clima ◽  
Dragos Lucian Isac ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Polyethylene Glycol ◽  
Gene Delivery ◽  
In Silico ◽  
Biomedical Applications ◽  
Experimental Studies ◽  
Biomedical Devices ◽  
In Silico Study ◽  
Or Gene

The biocompatible hydrophilic polyethylene glycol (PEG) is widely used in biomedical applications, such as drug or gene delivery, tissue engineering or as antifouling in biomedical devices. Experimental studies have shown...

scholarly journals Synthesis and characterizations of nano-silica for biomedical applications

2021 ◽  
Vol 10 (2) ◽  
pp. 114-118
Author(s):  
Huyen Nguyen Thi ◽  
Tam Lai Thi Thanh ◽  
Yudy Paola Monreno Gonzalez ◽  
Thinh Nguyen Ngoc ◽  
Mai Nguyen Thi Tuyet ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Biomedical Applications ◽  
Cetyltrimethylammonium Bromide ◽  
Average Length ◽  
Biological Applications ◽  
Nano Silica ◽  
Facile Synthesis ◽  
Structure Morphology ◽  
Ft Ir

This paper presents a facile synthesis of nano-silica by hydrothermal treatment assisted by cetyltrimethylammonium bromide (CTAB). The effect of CTAB on the morphology of the material was also investigated. Structure, morphology, and composition of the material were studied byvarious methods such as XRD, SEM, FT-IR, and EDX.The results showed that a sample of nanosilica with amount of 1,0 g CTAB at pH 10-11 reached the most appropriate size, with the average length and width are 231,34±48,98 nm và 113,05±16,45 nm, respectively. In addition, the results indicated that the nanoparticles are completely pure, with many silanol groups on the surface, suitable for applications in bone tissue engineering and other biological applications.

Recent advances of self-assembling peptide-based hydrogels for biomedical applications

Soft Matter ◽  
2019 ◽  
Vol 15 (8) ◽  
pp. 1704-1715 ◽  
Author(s):  
Jieling Li ◽  
Ruirui Xing ◽  
Shuo Bai ◽  
Xuehai Yan
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Wound Healing ◽  
Biomedical Applications ◽  
3D Bioprinting ◽  
Biological Applications ◽  
Antitumor Therapy ◽  
Self Assembling ◽  
Recent Advances

The review introduces several methods for fabrication of robust peptide-based hydrogels and their biological applications in the fields of drug delivery and antitumor therapy, antimicrobial and wound healing materials, and 3D bioprinting and tissue engineering.

Nanofibrous Substrate For Tissue Engineering Applications—A Review

2021 ◽  
Vol 8 (6) ◽  
pp. 13-21
Author(s):  
Odia Osemwegie ◽  
Lihua Lou ◽  
Ernest Smith ◽  
Seshadri Ramkumar
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Cell Culture ◽  
Tissue Regeneration ◽  
Biomedical Applications ◽  
High Volume ◽  
Clinical Applications ◽  
Critical Factors ◽  
Engineering Applications

Nanofiber substrates have been used for various biomedical applications, including tissue regeneration, drug delivery, and in-vitro cell culture. However, despite the high volume of studies in this field, current clinical applications remain minimal. Innovations for their applications continuously generate exciting prospects. In this review, we discuss some of these novel innovations and identify critical factors to consider before their adoption for biomedical applications.

Biomedical applications of polymers 2001 - 2002

e-Polymers ◽  
2003 ◽  
Vol 3 (1) ◽  
Author(s):  
Joseph Jagur-Grodzinski
Keyword(s):  
Tissue Engineering ◽  
Gene Therapy ◽  
Gene Delivery ◽  
Drug Release ◽  
Wound Dressing ◽  
Biomedical Applications ◽  
Bone Repair ◽  
Controlled Drug Release ◽  
Artificial Organs ◽  
Drug And Gene Delivery

Abstract Papers published during 2001 - 2002 on the synthesis and preparation of polymers and polymer-based devices and their applications are reviewed. Polymers for drug and gene delivery, gene therapy, controlled drug release, conjugation with peptides, proteins, and nucleotides, tissue engineering, bone repair and regeneration, coatings, wound dressing, artificial skin and other artificial organs are discussed.

Engineering β-sheet peptide assemblies for biomedical applications

2016 ◽  
Vol 4 (3) ◽  
pp. 365-374 ◽  
Author(s):  
Zhiqiang Yu ◽  
Zheng Cai ◽  
Qiling Chen ◽  
Menghua Liu ◽  
Ling Ye ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Cell Culture ◽  
Biomedical Applications ◽  
Β Sheet

Hydrogels have been widely studied in various biomedical applications, such as tissue engineering, cell culture, immunotherapy and vaccines, and drug delivery.

Laponite-based Nanomaterials for Biomedical Applications: A Review

2019 ◽  
Vol 25 (4) ◽  
pp. 424-443 ◽  
Author(s):  
Sabya S. Das ◽  
Neelam ◽  
Kashif Hussain ◽  
Sima Singh ◽  
Afzal Hussain ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Cell Adhesion ◽  
Targeted Drug Delivery ◽  
Biomedical Applications ◽  
Biodegradable Materials ◽  
Clay Material ◽  
Research Directions ◽  
Targeted Drug ◽  
Cell Adhesion And Proliferation

Laponite based nanomaterials (LBNMs) are highly diverse regarding their mechanical, chemical, and structural properties, coupled with shape, size, mass, biodegradability and biocompatibility. These ubiquitous properties of LBNMs make them appropriate materials for extensive applications. These have enormous potential for effective and targeted drug delivery comprised of numerous biodegradable materials which results in enhanced bioavailability. Moreover, the clay material has been explored in tissue engineering and bioimaging for the diagnosis and treatment of various diseases. The material has been profoundly explored for minimized toxicity of nanomedicines. The present review compiled relevant and informative data to focus on the interactions of laponite nanoparticles and application in drug delivery, tissue engineering, imaging, cell adhesion and proliferation, and in biosensors. Eventually, concise conclusions are drawn concerning biomedical applications and identification of new promising research directions.

scholarly journals ADVANCES OF NON-IRON METAL NANOPARTICLES IN BIOMEDICINE

2021 ◽  
Vol 24 ◽  
pp. 41-61
Author(s):  
Anroop B. Nair ◽  
Mohamed A. Morsy ◽  
Pottathil Shinu ◽  
Sabna Kotta ◽  
Mithra Chandrasekaran ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Antimicrobial Activity ◽  
Gene Delivery ◽  
Anticancer Activity ◽  
Metal Nanoparticles ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Metallic Elements ◽  
Iron Metal

Metal nanoparticles (MNPs) comprise of nanoparticles originating from metallic elements with additional properties inherent to metal ions. MNPs found applications in various field such as electronics, optics, mechanics, physics etc. There are many reviews on iron MNPs for biomedical application. Hence, in this review, we focus on non-iron MNPs and their vivid biomedical applications. Here, we review the applications of non-iron MNPs in biomedicine such as drug delivery, gene delivery, anticancer activity, antimicrobial activity, tissue engineering, bioimaging, and photodynamic, and photothermal therapies.

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