scholarly journals Prevalence and Factors Associated with Depression among HIV/AIDS-Infected Patients Attending ART Clinic at Jimma University Medical Center, Jimma, Southwest Ethiopia

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Beyene Dorsisa ◽  
Gutema Ahimed ◽  
Susan Anand ◽  
Tariku Bekela
Keyword(s):  
Medication Adherence ◽  
Marital Status ◽  
Opportunistic Infection ◽  
Medical Center ◽  
Bivariate Analysis ◽  
People Living With Hiv ◽  
Southwest Ethiopia ◽  
Factors Associated ◽  
Jimma University ◽  
Hiv Aids

Background. HIV is a chronic life-threatening illness and, like other similar chronic and stigmatizing illnesses, can be stressful to manage. Depression is a common mental health problem that deteriorates the quality of life of people with HIV/AIDS and found to be a strong predictor for noncompliance to antiretroviral therapy treatment. Therefore, epidemiological evidence on the factors associated with depression among patients with HIV/AIDS can contribute towards effective and efficient preventive health care strategies for this population. Objectives. To assess the prevalence and factors associated with depression among HIV/AIDS-infected patients attending ART clinic at Jimma University Medical Center, Jimma, Southwest Ethiopia, in 2018. Methods. This study followed an institution-based cross-sectional quantitative study design. A simple random sampling method yielded 303 participants who were interviewed from April to May 2018, using a pretested questionnaire, followed by their card review. The SPSS version 23 was used for bivariate analysis which was used to find out the significance of association. Variables that showed association in bivariate analysis at p value < 0.25 were entered to multivariable logistic regressions to control for confounders, and the significance of association was determined by 95% confidence interval and p value < 0.05. Results. The point prevalence of depression was 94 (31%). Variables like sex (AOR=0.510 (95%CI=0.264‐0.986)), marital status (AOR=3.610 (95%CI=1.649‐7.901)), opportunistic infection (AOR=3.122 (95%CI=1.700‐5.733)), and medication adherence (AOR=0.470 (95%CI=0.266‐0.831)) were significantly associated with depression. Conclusion and Recommendation. From the findings of this study, it is possible to conclude that depression was highly prevalent among people living with HIV/ADS. Sex, marital status, opportunistic infection, and medication adherence were found to be associated with depression and need attention from the health professional working in the ART clinic.

scholarly journals Determinants of Fertility Desire among Women Living with HIV in the Childbearing Age Attending Antiretroviral Therapy Clinic at Jimma University Medical Center, Southwest Ethiopia: A Facility-Based Case-Control Study

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Nigusie Shifera Aylie ◽  
Lelisa Sena Dadi ◽  
Eshetu Alemayehu ◽  
Mengistu Ayenew Mekonn
Keyword(s):  
Medical Center ◽  
Fertility Desire ◽  
Childbearing Age ◽  
Southwest Ethiopia ◽  
Women Living With Hiv ◽  
Living With Hiv ◽  
Jimma University ◽  
Therapy Clinic ◽  
Control Study ◽  
Hiv Aids

Background. High fertility and aspiration to have more children are a normal phenomenon in many developing countries including Ethiopia. The desire of people living with HIV/AIDS (PLWHA) to have children can have significant public health implications. Despite the growing number of women living with HIV/AIDS, the issues of fertility and childbearing intention have not been widely studied in Ethiopia. Objective. To identify determinants of fertility desire among women living with HIV in the childbearing age attending antiretroviral therapy clinic at Jimma University Medical Center, Southwest Ethiopia. Methods. A facility-based case-control study was conducted in March 2019. Cases were women living with HIV who had fertility desire, and controls were those who had not. Data was collected using a face-to-face interview using a pretested questionnaire. The data was entered into EpiData 3.1 and exported to SPSS Version 24 for analysis. Bivariate and multivariable logistic regression analyses were used to identify candidate and independent determinants of fertility desire, respectively. Independent determinants associated with fertility desire were assessed using AORs with their corresponding 95% CIs at P value < 0.05 cutoff point. Results. Three hundred forty-four (115 cases and 229 controls) were included into the study with a 100% response rate. Age categories 15-24 (AOR: 4.1; 95% CI: 2.0, 8.4) and 25-34 (AOR: 2.3; 95% CI: 1.3, 4.2) years, not using family planning (AOR: 2.3; 95% CI: 1.4, 4.0), and having a sexual partner (AOR: 1.9; 95% CI: 1.1, 3.2) were independent predictors of fertility desire. Conclusions. Age of women, family planning, and sexual partner were found to be the independent predictors of fertility desire among women living with HIV/AIDS. Policymakers and health care providers who are working on an ART clinic should try to consider the effects of these factors for women living with HIV while developing HIV/AIDS interventions and discussing on sexual and reproductive health issues with their clients, respectively.

scholarly journals Prevalence of malnutrition and associated factors among adult patients on Antiretroviral Therapy follow up care in Jimma Medical Center, Southwest Ethiopia

2019 ◽  
Author(s):  
Dawit Wolde Daka ◽  
Meskerem Seboka Ergiba
Keyword(s):  
Medical Center ◽  
Severe Malnutrition ◽  
People Living With Hiv ◽  
Aids Patients ◽  
Southwest Ethiopia ◽  
Under Nutrition ◽  
Follow Up Care ◽  
Clinical Records ◽  
Hiv Aids

AbstractBackgroundMalnutrition especially under nutrition is the main problem that is seen over people living with HIV/AIDS and can occur at any age. Multiple factors contributed to malnutrition of HIV/AIDS patients and it need immediate identification and prompt action. The objective of this study was to assess the nutritional status of patients and identify factors associated with malnutrition among HIV/AIDS patients on follow-up care in Jimma medical center, Southwest Ethiopia.MethodsA cross-sectional study design was conducted from March-April, 2016. Data was collected retrospectively from clinical records of HIV/AIDS patients enrolled for follow up care in ART clinic from June 2010 to January 2016. Binary and multiple variable logistic regression was done to identify independent predictor of malnutrition.ResultsData of 971 patients were included in the study. The prevalence of under nutrition (BMI<18.5) was (36.8%) (95% CI: 33.8%-39.8%) and out of which severe malnutrition accounts 9.7%. Overweight and obese was 8.6%. Malnutrition was more likely among widowed patients (AOR=1.7, 95% CI, 1.034-2.798), patients in the WHO clinical AIDS staging of three (AOR=2.3, 95% CI, 1.392-3.693) and four (AOR=3.2, 95% CI, 1.667-5.943), patients with CD4 cell count of <200 cells/mm3 (AOR=2.0, 95% CI, 1.463-2.837) and patients with a functional status of bedridden (AOR=4.677, 95% CI, 1.761-12.419) and ambulatory (AOR=2.763, 95% CI, 1.833-4.165).ConclusionBoth under nutrition and overweight are prevalent among HIV/AIDS patients in Jimma Medical Center, Ethiopia. Malnutrition was significantly associated with clinical outcome of patients. Hence, nutritional assessment, care and support should be strengthened. Critical identification of malnourished patients and prompt interventions should be undertaken.

scholarly journals The factors associated with co-trimoxazole hypersensitivity in people living with HIV/AIDS: a retrospective study

2020 ◽  
Vol 7 (11) ◽  
pp. 1726
Author(s):  
Ketut Suryana ◽  
Hamong Suharsono ◽  
Mochamad P. Pujasakti
Keyword(s):  
Retrospective Study ◽  
Hypersensitivity Reaction ◽  
Opportunistic Infection ◽  
Fixed Dose ◽  
People Living With Hiv ◽  
Duration Of Treatment ◽  
Factors Associated ◽  
History Of ◽  
Living With Hiv ◽  
Hiv Aids

Background: Antibiotic adverse drug reactions (ADRs) can occurred during any treatment of infection, especially opportunistic infections in people living with HIV/AIDS (PLWHA). Co-trimoxazole is a sulfonamide fixed dose combination antibiotic, consisted of sulfamethoxazole and trimethoprim which is effective in treatment of several infections and for prophylaxis of pneumocystis jiroveci pneumonia. The universal use of co-trimoxazole for prophylaxis has been shown to decrease hospitalizations, morbidity and mortality among PLWHA, but potentially associated with ADRs include drug hypersensitivity reaction. The objective was to identify factors associated with co-trimoxazole hypersensitivity in PLWHA.Methods: A retrospective study were enrolled 404 participants PLWHA who were received co-trimoxazole due to co-trimoxazole prophylaxis therapy (CPT), between January 2015–December 2018. The independence variables such as age, sex, history of allergy, hypersensitivity reactions, duration of therapy (days), CD4 (cells/µl) and opportunistic infection to co-trimoxazole hypersensitivity reaction were analyzed using spearman test.Results: Mostly of the participants was male: 253 (62.60%). Eighteen (4.50%) with history of allergy, 64 (15.90%) were known co-trimoxazole hypersensitivity reaction. The most frequent clinical manifestation was maculopapular rash: 27 (42.3%), followed by urticaria alone: 17 (26.3%), fixed drug eruption: 12 (19.6%), and angioedema with or without urticaria: 8 (11.8%). The history of allergy, opportunistic infection and duration of treatment were associated factors to co-trimoxazole hypersensitivity reaction.Conclusions: This study was identified, that history of allergy, duration of treatment and opportunistic infection were factors associated with co-trimoxazole hypersensitivity in PLWHA.

scholarly journals Impact of Sleep Disturbances on the Quality of Life Among Schizophrenic Out-patients of Jimma University Medical Center, Southwest Ethiopia: Hospital Based Cross-sectional Study

2020 ◽  
Vol 13 (1) ◽  
pp. 684-691
Author(s):  
Aman Dule ◽  
Mustefa Mohammedhussein ◽  
Mohammedamin Hajure
Keyword(s):  
Quality Of Life ◽  
Sleep Disturbances ◽  
Medical Center ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Southwest Ethiopia ◽  
Schizophrenic Patients ◽  
Jimma University

Aim: Current study was aimed to assess the impacts of sleep disturbances on patient’s quality of life. Background: Schizophrenia is a syndrome, which affects sleep. Up to 80% of schizophrenic patients complain of sleep disturbances which affect the quality of life Objectives: To assess the association of sleep disturbances and quality of life and other contributing factors among schizophrenic patients on follow-up treatment at Jimma University Southwest Ethiopia. Methods: A cross-sectional study with a consecutive sampling of 411 out-patients at Jimma University medical center was employed from April 21-June 20, 2019. Sleep disturbances and the quality of life were assessed by Pittsburgh sleep quality index and WHOQOL-BREF, respectively. Epi data version 3.1 and SPSS version 23.0 software was used. Chi-square and independent samples t-test were used for association and P-value < 0.05 was considered for statistical significance. Results: Most participants had sleep disturbances and the mean score of positive scale on PANSS was higher for patients with sleep disturbances. About one-fourth of the patients had very good subjective sleep quality and > 85% of sleep efficiency was reported by 139 participants. More than half (51.1%) of the subjects had used sleep medication and the majority (64.7%) of them were reported daytime dysfunctions in the past month. The social domain (M±SD=3.92±2.51, t=8.46, p= <0.001, eta2=0.15) and overall WHOQOL (M±SD=57.60±16.87, t=9.24, p= < 0.001, eta2= 0.17) score had a large difference of means and about 15% and 17% of the variance in sleep disturbance have been explained. Conclusion: Generally, the finding of the current study was in agreement with most of the previous studies and sleep disturbances respectively moderate to significant effects on the patient’s quality of life.

scholarly journals Efek Samping Terapi Antiretroviral dan Kepatuhan Berobat Penderita HIV/AIDS

2021 ◽  
Vol 12 (3) ◽  
pp. 389
Author(s):  
Rico Januar Sitorus ◽  
Novrikasari Novrikasari ◽  
Rizma Adliah Syakurah ◽  
Merry Natalia
Keyword(s):  
Medication Adherence ◽  
Side Effects ◽  
Opportunistic Infection ◽  
Multivariate Regression Analysis ◽  
Adherence Rate ◽  
P Value ◽  
Cross Sectional ◽  
Treatment Side Effects ◽  
The City ◽  
Hiv Aids

<p>Antiretroviral treatment side-effects and patient compliance with medical instructions continue to be a growing challenge for HIV/AIDS patients. Arv therapy has resulted in a substantial intervention that has been successful in preventing transmission and opportunistic infection. The main objective of this study was to analyze the association between side-effects of ARV therapy and medication adherence as well as another potential confounding such as opportunistic infection, family support, stress level, knowledge of ARV, marital status, and occupation. This study is a quantitative approach by using cross-sectional methods. A total of 244 respondents from 1.180 patients with confirmed HIV registered in the Care Support and Treatment (CST) service and Sriwijaya Community in the City of Palembang to respond to the survey. Non-random sampling was used to collect the samples. As the result, the majority of the respondents were male (84,43 %), ≥30 years old (57,4%), and secondary school graduates (52%). After adjusting with stress and opportunistic infection variable, a Multivariate regression analysis revealed a positive relationship between side effects and medication adherence (p-value of 0,041; 0,05), OR Adj 2,131 (1,190-4,988). PLHV who had adverse effects had a 2.131 times worse adherence rate than those who did not. In conclusion, medication adherence must be greatly improved in light of therapeutic side effects, stress levels, and opportunistic infection.</p>

scholarly journals STUDI RETROSPEKTIF KETAHANAN HIDUP ORANG DENGAN INFEKSI HIV/AIDS (ODHA) DI RSUD DR. ACHMAD MOCHTAR BUKITTINGGI

2019 ◽  
Vol 3 (3) ◽  
pp. 175
Author(s):  
Sukarsi Rusti
Keyword(s):  
Opportunistic Infection ◽  
Opportunistic Infections ◽  
Analysis Data ◽  
P Value ◽  
People Living With Hiv ◽  
Chi Square ◽  
The People ◽  
Living With Hiv ◽  
Hiv Aids

<p><em>H</em><em>I</em><em>V/AIDS disease is a health problem in indonesia. The problem cause of</em><em> </em><em>the number of morbility and mortality that still hight. It is cause of long term</em><em> </em><em>infection, adherance consuming the drungs and opportunistic that can deastroy the</em><em> </em><em>imun system </em><em>of People Living With HIV/AIDS (PLHIV)</em><em>.  The purpose of this research is to identify the factors</em><em> </em><em>related to the people living with </em><em>PLHIV</em><em> </em><em>in Achmad Muchtar Hospital Bukittinggi</em></p><p><em>2016.</em><em></em></p><p><em>This research was conducted by a retrospective cohort design approach, doing  research  of the death of people who living with HIV by observing the patient’s  medical  record  from  2014-2015.  The  research  of  study  were  215 patient’s  who  is  criteria  inclusion.  Analysis  data  using  test  chi-square.  who became the independent  variable is  long  infection,  adherance  comsuming the </em><em>Anti Retroviral (ARV)</em><em> </em><em>, and opportunistic infection and dependent variable that survive the HIV people life.</em><em></em></p><p><em>The research showed that among  215 patients with the number of deaths 39 people ( 18,% ), stages 3 and 4 (&gt;5 th) is 89 people ( 41.4% ), not adherence is  77 people ( 35.8% ), and who suffered an opportunistic infection were 61 people (28.4% ). The statistical test relationships survival of people  living with</em><em> </em><em>H</em><em>I</em><em>V with long-term  infection obtained p value </em><em>=</em><em> </em><em>0,000</em><em> and </em><em>RR = 0,019 ( confidence interfal 95 % with alpha = 0.05 )</em><em>, </em><em>a</em><em>dherance comsuming the </em><em>ARV </em><em>obtained p value  </em><em>= </em><em>0,000 </em><em>and</em><em>  </em><em>RR = 0,494 ( confidence interfal  95 % with alpha = 0.05 ), infection opportunistic</em><em> obtained</em><em> </em><em>p value </em><em>= </em><em>0,000 </em><em>and</em><em> </em><em>RR = 0,361 ( confidence interfal 95 % with αlpha = 0.05 ).</em></p><p><em>From these findings, it can be concluded that  the  long-term  infection,  adherence  ARV  and opportunistic infections associated with survival of people living with HIV. Of the three variables obtained interrelated and value the highest association is long-term  infection</em><em>.</em></p>

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