scholarly journals Glomangioma of Uncertain Malignant Potential: A Case Report

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Meghan McCullough ◽  
Bonnie Balzer ◽  
Stuart H. Kuschner

Glomus tumors are rare benign tumors which commonly affect the hand but are seldom seen extradigitally. Less commonly seen is the glomangioma, a variant of benign glomus tumor, and even rarer is the glomangiosarcoma, a malignant variant. Determining malignancy can be difficult and an intermediate diagnosis, glomus tumor of uncertain malignant potential, has been proposed. We present a case of a 56-year-old male with a recurrent forearm mass diagnosed as a glomangioma of uncertain malignant potential. Although the characteristics and behavior of malignant cases are still incompletely understood, it is important that a high index of suspicion be maintained when approaching these tumors, especially when large or recurrent. Glomangiomas should be included in the differential diagnosis when evaluating soft tissue masses in the forearm and should be evaluated for malignant features.

2020 ◽  
Vol 3 (1) ◽  
pp. 14-17
Author(s):  
Mehta Shailee ◽  
◽  
Dabral Ritwika ◽  
Trivedi Priti ◽  
◽  
...  

Glomus tumor is usually a small, benign tumor and typically occurs in the dermis or subcutis or soft tissues of the extremities and rarely in the visceral locations. Its bronchopulmonary origin is exceedingly rare clinical condition. The current case reported a 51-year-old male with dyspnea on exertion and obstructive pneumonia; he had a glomus tumor which has large size, deep location and exhibits an infiltrative margin as well as atypical mitotic figures. These characteristic suggests malignant behavior. Therefore diagnosis of glomus tumor of uncertain malignant potential was favored. Recently, the histopathological diagnostic criteria for malignant glomus tumors were defined in the WHO classification of soft tissue and bone tumors 4th edition. Here we also reviewed the literature on primary bronchopulmonary glomus tumors with special attention to the current concept of malignancy grade estimation.


2019 ◽  
Vol 7 (23) ◽  
pp. 4082-4088
Author(s):  
Violeta Vasilevska-Nikodinovska ◽  
Milan Samardjiski ◽  
Rubens Jovanovik ◽  
Boro Ilievski ◽  
Vesna Janevska

BACKGROUND: Glomus tumors are rare neoplasms accounting for less than 2% of all soft tissue tumors but multiple lesions may be seen in up to 10% of the patients. Solitary glomus tumor (GT) most frequently appears as small nodule in specific locations such as subungual region or deep dermis. However, rarely these entities have been observed in extracutaneous locations such as the gastrointestinal, cardiovascular, respiratory tracts, and other visceral organs. A small fraction of the GTs may present as tumors of uncertain malignant potential or as malignant glomus tumors. CASE PRESENTATION: We report a patient with multiple glomus tumors on the time of diagnosis, which was histologically diagnosed as an atypical glomus tumor following resection of a tumor thrombus in the left renal vein, inferior vena cava trombus with intracardial extension, and mitral valve specimen. The intramuscular lesion from the thigh was diagnosed as a glomus tumor of uncertain malignant potential. Further examinations revealed multiple lesions trough her body: kidneys, breast, heart and subcutaneous tissue. The diagnosis of glomus tumor of uncertain malignant potential versus glomus tumor with low malignant potential could be quite challenging, and the clinical course may be as a determining factor for final diagnosis. CONCLUSION: To our knowledge, this is the only known case of glomus tumor with multiple organ involvement and aggressive biological behavior at presentation.


2019 ◽  
Vol 7 (18) ◽  
pp. 2815-2822
Author(s):  
Pichaya Thanindratarn ◽  
Thanapon Chobpenthai ◽  
Termphong Phorkhar ◽  
Scott D Nelson

2020 ◽  
Vol 2 (1) ◽  
pp. 01-04
Author(s):  
Rolanda A. Willacy

Glomus bodies are neuromyoarterial apparatuses of the skin, implicated in body temperature control, and may undergo transformation with unregulated hyperplasia of their smooth muscle component. Glomus tumors most commonly occur in the subungual region of the fingers. These benign tumors are rare and constitute 1-5% of soft tissue tumors of the hand and may present as solitary or multiple masses. Solitary glomus tumors present with a classic triad of localized tenderness, severe pain, and cold sensitivity. We report a rare case of glomus tumor in the elbow and a review of the histopathological findings.


2020 ◽  
Vol 110 (6) ◽  
Author(s):  
Erin M. Kunz ◽  
Bebu Ram

Glomus tumors are rare and benign vascular soft-tissue masses commonly found subungually in the foot. A glomus tumor typically manifests with a classic triad of pain, point tenderness, and cold sensitivity. This case report describes an atypical presentation of a glomus tumor in the soft tissue of the rearfoot in a 77-year-old man in the setting of urosepsis. The mass had enlarged progressively for 6 months. Originally misdiagnosed as a hemangioma based on magnetic resonance imaging and clinical appearance, an excisional biopsy was performed. The lesion was subsequently diagnosed histopathologically as a glomus tumor. This article discusses the statistics of glomus tumor and discusses the importance of the need to recognize the symptoms and clinical findings of both typical and atypical presentation of this abnormality in differentiation and differential treatment and risk management of benign and malignant soft-tissue masses.


Author(s):  
Rajeshwari K. A. ◽  
Rajagopal R.

<div class="WordSection1"><p class="abstract">Glomus tumors are rare soft-tissue neoplasms of the neuromyoarterial glomus body, typically present in adults as small, blue-red papules or nodules of the distal extremities, with most cases involving subungual sites. The majority of glomus tumors are benign, malignant cases have been rarely reported, with such cases typically being locally invasive. 27 years old patient presented with four years history of intermittent swelling, pain in left lower leg. Biopsy of the lesion revealed lobulated vascular tumour composed of endothelial cells showing intracytoplasmic lumina and solid aggregates of tumour cells, divided by intervening fibrocollagenous septae. Glomus tumour of uncertain malignant potential was diagnosed after excision biopsy. Multispeciality team approach was done for complete cure of the condition.</p></div>


2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Yuxi Li ◽  
Kaihui Su ◽  
Ming Li ◽  
Shixin Lu ◽  
Zhen Che ◽  
...  

1970 ◽  
Vol 1 (1) ◽  
pp. 66-68
Author(s):  
R Baral ◽  
H Limbu

Glomus tumors closely resemble the normal glomus body and have a predilection for skin and subcutaneous tissue. Clinically, Glomus tumors are present on the nail bed and are of less than 1 cm. We report a case of a male who presented with a 3 month history of swelling in the left thumb which was mildly tender. The swelling measured 6 x 6.5 cm. On microscopy the tumor showed mild atypia with increased mitotic activity. These features, by current definition, would suggest uncertain malignant potential. Keywords: Glomus tumor; Glomangioma; Merkel cell carcinoma.DOI: 10.3126/jpn.v1i1.4457 Journal of Pathology of Nepal (2011) Vol.1, 66-68  


2021 ◽  
pp. 154431672199913
Author(s):  
Jessica Kralec

Glomus tumors are small, painful benign tumors that occur primarily in the subungual region of the hand. The presentation of glomus tumors in areas other than the hand is rare, but have been reported. Patients with glomus tumors have a prolonged history of focal pain, tenderness, and cold hypersensitivity. However, as all 3 symptoms may not present simultaneously, it can present a diagnostic challenge to clinicians and imagers, often remaining undiagnosed or misdiagnosed for many years. We report a case of an extradigital glomus tumor of the right thigh that was initially diagnosed as focal superficial thrombophlebitis. The diagnosis of glomus tumor was pathologically proven.


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