scholarly journals scFv against HSP60 of Strongyloides sp. and Its Application in the Evaluation of Parasite Frequency in the Elderly

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Camila Botelho Miguel ◽  
Marcelo Arantes Levenhagen ◽  
Julia Maria Costa-Cruz ◽  
Luiz Ricardo Goulart ◽  
Patrícia Terra Alves ◽  
...  
Keyword(s):  
Serological Test ◽  
The Elderly ◽  
Single Chain ◽  
Recent Infection ◽  
Serological Method ◽  
Elderly Individuals ◽  
Strongyloides Venezuelensis ◽  
Epidemiological Tool ◽  
Antigen Purification

The present study is aimed at evaluating serological method using scFv anti-Strongyloides sp. and reporting the frequencies of the results with conventional parasitological technique (faeces) in elderly individuals. Among 112 elderly individuals (≥60 years of age), 14.28% were positive for at least one enteroparasite, with one individual positive for S. stercoralis. Sera were evaluated for the presence of anti-Strongyloides sp. antibodies using total or detergent fraction extracts of Strongyloides venezuelensis, which presented positivity rates of 19.64% and 10.71%, respectively. An anti-HSP60 single-chain variable fragment from Strongyloides sp. was used to detect parasite antigens, with 5.36% (6 individuals) of ELISA-positive individuals returning a positive result. While the serological test indicates previous or recent infection and may be limited by antigen purification, the anti-HSP60 method reflects the presence of Strongyloides sp. immune complexes and exhibits greater sensitivity and specificity. Our results demonstrate the variable occurrence of enteroparasites in elderly individuals residing in long-term nursing homes and validate a novel epidemiological tool to describe infection cases by Strongyloides sp.

scholarly journals The Camberwell Assessment of Need for the Elderly questionnaire as a tool for the assessment of needs in elderly individuals living in long-term care institutions

2016 ◽  
Vol 62 ◽  
pp. 163-168 ◽  
Author(s):  
Katarzyna Wieczorowska-Tobis ◽  
Dorota Talarska ◽  
Sylwia Kropińska ◽  
Krystyna Jaracz ◽  
Sławomir Tobis ◽  
...  
Keyword(s):  
Long Term Care ◽  
The Elderly ◽  
Term Care ◽  
Elderly Individuals ◽  
Camberwell Assessment Of Need ◽  
Assessment Of Need

Clinical outcome and long-term survival following radical esophagectomy in the elderly

2001 ◽  
Vol 120 (5) ◽  
pp. A747-A748
Author(s):  
S DRESNER ◽  
A IMMMANUEL ◽  
P LAMB ◽  
S GRIFFIN
Keyword(s):  
Clinical Outcome ◽  
The Elderly ◽  
Radical Esophagectomy ◽  
Term Survival ◽  
Long Term Survival

Status and Degree of Dysphagia in the Elderly-A Comparison Study of Long-Term Care Elderly People in an Outpatient Clinic

2003 ◽  
Vol 54 (4) ◽  
pp. 277-284 ◽  
Author(s):  
Masanori Komatsu ◽  
Kayoko Hirata ◽  
Idumi Mochimatsu ◽  
Kazuo Matsui ◽  
Hajime Hirose ◽  
...  
Keyword(s):  
Elderly People ◽  
Outpatient Clinic ◽  
Long Term Care ◽  
The Elderly ◽  
Comparison Study ◽  
Term Care

Historical and medical aspects of the organization of medical and social services for the elderly and senile people in Russia in the late XX — early XXI centuries

2020 ◽  
pp. 49-57
Author(s):  
Lyudmila Kaspruk
Keyword(s):  
Health Care ◽  
Social Services ◽  
Social Protection ◽  
The Elderly ◽  
Primary Role ◽  
Primary Health ◽  
Geriatric Service ◽  
Delivery Of Medical Care ◽  
Older Citizens

When analyzing the historical and medical aspects of the organization of medical and social services for the elderly and senile people in Russia in the late XX — early XXI centuries not only obvious achievements in this sphere, but also a number of problems requiring solution were identified. The primary role in the delivery of medical care to geriatric patients is assigned to the primary health care sector. However the work of the geriatric service in the format of a single system for the provision of long-term medical and social care based on the continuity of patient management between differ- ent levels of the health care system and between the health and social protection services is not well organized. There is no clear coordination and interaction between health care and social protection institutions, functions of which include providing care to older citizens, and it significantly reduces the effectiveness of the provision of both medical and social services.

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