scholarly journals A Case of Acute Esophageal Necrosis from Unruptured Thoracic Aortic Aneurysm

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Abhishek Polavarapu ◽  
Dhineshreddy Gurala ◽  
Bindu Mudduluru ◽  
Pretty Sara Idiculla ◽  
Jobin Philipose ◽  
...  

Acute esophageal necrosis (AEN), also known as black esophagus due to its appearance on endoscopy, classically involves the distal esophagus (97% of cases). AEN affecting the midesophagus with sparing of the distal esophagus is rare and usually occurs in patients with thoracic aortic aneurysmal (TAA) rupture or aortic dissection. Herein, we report a unique case of AEN in the midesophagus in a patient with an unruptured and undissected TAA.

2018 ◽  
Vol 2018 ◽  
pp. 1-3 ◽  
Author(s):  
Zachary Field ◽  
Jacqueline Kropf ◽  
Meghan Lytle ◽  
Giselle Castaneira ◽  
Mario Madruga ◽  
...  

Background. Acute esophageal necrosis is an uncommon clinical disorder diagnosed on endoscopy as a black esophagus. It has a multifactorial etiology that probably represents a combination of poor nutritional status, gastric outlet obstruction, and ischemia secondary to hypoperfusion of the distal esophagus. It typically occurs in older males with comorbidities. Case. A 37-year-old woman presented with diabetic ketoacidosis and hematemesis. At esophagogastroduodenoscopy acute esophageal necrosis was diagnosed. The treatment included fluid and electrolyte management, insulin, and a proton pump inhibitor. She improved and left the hospital on day 3. Conclusion. Diabetic ketoacidosis can result in a profound osmotic diuresis, fluid loss, and hypoperfusion of the distal esophagus. This condition can then lead to ischemic injury and acute esophageal necrosis. Awareness of the possibility of its presence in young women with hematemesis and poorly controlled diabetes is important since early identification with esophagogastroduodenoscopy is necessary to prevent serious postnecrotic complications.


2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Katelyn Hodge ◽  
Katherine G. Spoonamore ◽  
Christopher B. Griffith ◽  
David D. Weaver ◽  
Patricia B.S. Celestino-Soper ◽  
...  

We report on the process of <em>post mortem</em> evaluation and genetic testing following the death of a 25-year-old man due to ascending aortic dissection leading to aortic rupture. Following the negative clinical testing of a 12- gene thoracic aortic aneurysm and dissection panel, research testing revealed a novel c.5732A&gt;T (p.E1911V) variant in exon 34 of the MYLK gene (NM_053025). Two likely pathogenic variants in this gene have been reported previously in individuals with familial thoracic aortic aneurysm and dissection. Given the unclear clinical consequence of the variant found in our proband, we have classified this change as a variant of uncertain significance. In addition to discussing the complexity involved in variant interpretation, we recognize the need for additional research for more accurate <em>MYLK</em> interpretation. Finally, we comment on the unique challenges of <em>post mortem</em> genetic testing.


2014 ◽  
Vol 109 ◽  
pp. S225
Author(s):  
Hiren Patel ◽  
Deepshikha Nag Chowdhury ◽  
Nihar Shah ◽  
Arya Karki ◽  
Robert Spira

2011 ◽  
Vol 212 (1-3) ◽  
pp. e15-e17 ◽  
Author(s):  
Kana Unuma ◽  
Kazuki Harada ◽  
Takeshi Funakoshi ◽  
Koichi Uemura

2017 ◽  
Vol 54 (11) ◽  
pp. 1061-1063 ◽  
Author(s):  
Valerio Manno ◽  
Nicola Lentini ◽  
Antonio Chirico ◽  
Maria Perticone ◽  
Luigi Anastasio

2007 ◽  
Vol 21 (4) ◽  
pp. 245-247 ◽  
Author(s):  
Ahmad Burtally ◽  
Philippe Gregoire

Acute esophageal necrosis (AEN), also called black esophagus, is quite exceptional. Endoscopic findings show circumferential black discolouration of the esophagus with or without exudates. The etiology of AEN is presently unknown and is assumed to be multifactorial. Distal esophageal involvement with proximal extension ending sharply at the gastroesophageal junction is the most common presentation. The present case report describes the clinical and endoscopic evolution of black esophagus observed in a patient with significant peripheral vascular disease, who was presented to the intensive care unit at the Hopital Saint-Francois d’Assise (Quebec City, Quebec). Through an extensive review of the literature, common underlying clinical conditions of patients diagnosed with AEN have been identified.


2019 ◽  
Vol 91 (1) ◽  
pp. 48-51 ◽  
Author(s):  
Jawed Akhtar ◽  
Vijaya Kumar Gorantla ◽  
Peter D. Snell ◽  
Barry M. Wall

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