scholarly journals Theanine-Modified Graphene Oxide Composite Films for Neural Stem Cells Proliferation and Differentiation

2020 ◽  
Vol 2020 ◽  
pp. 1-10 ◽  
Author(s):  
Zhiping Qi ◽  
Xue Chen ◽  
Wenlai Guo ◽  
Chuan Fu ◽  
Su Pan

The central nervous system (CNS) injury has been a worldwide clinical problem for regenerative medicine. Nerve tissue engineering is a new strategy for CNS injury. Among kinds of biomaterials, graphene oxide (GO)-based degradable composite materials are considered to be promising in the field of neurogenesis. In this study, GO and L-theanine (TH) were combined by chemical grafting to prepare a new PLGA/GO-TH composite material. X-ray diffraction (XRD), transmission electron microscope (TEM), Fourier-transform infrared spectra (FTIR), contact angle testers, and mechanical testers were performed to obtain characterization of composite materials. The protein adsorption efficiency of the PLGA/GO-TH films was then evaluated. Next, the effect of the composite films on neural stem cell (NSC) survival, proliferation, and differentiation was investigated. Our results indicated that L-theanine was successfully grafted onto GO. PLGA/GO-TH composite film can significantly improve NSC survival, proliferation, and neuronal differentiation. Our results demonstrated that the neurogenesis function of a novel PLGA/GO-TH composite film and its potential as a carrier for the further application in the CNS injury.

RSC Advances ◽  
2020 ◽  
Vol 10 (73) ◽  
pp. 44834-44834
Author(s):  
Qunpeng Duan ◽  
Lijie Wang ◽  
Fei Wang ◽  
Hongsong Zhang ◽  
Kui Lu

Correction for ‘Direct electrodeposition of cationic pillar[6]arene-modified graphene oxide composite films and their host–guest inclusions for enhanced electrochemical performance’ by Qunpeng Duan et al., RSC Adv., 2020, 10, 21954–21962, DOI: 10.1039/D0RA03138K.


RSC Advances ◽  
2021 ◽  
Vol 11 (28) ◽  
pp. 17108-17115
Author(s):  
Mahnaz Mirheidari ◽  
Javad Safaei-Ghomi

GO@f-SiO2@Co is a heterogenous catalyst composed of spherical silica particles grafted on the surface of graphene oxide with ethylenediamine ligands and coordination with Co(ii). We assessed the activity of the catalyst for the synthesis of aminonaphthoquinones.


2015 ◽  
Vol 50 (16) ◽  
pp. 5389-5401 ◽  
Author(s):  
Bihe Yuan ◽  
Haibo Sheng ◽  
Xiaowei Mu ◽  
Lei Song ◽  
Qilong Tai ◽  
...  

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