scholarly journals Malaria in Pregnancy in Endemic Regions of Colombia: High Frequency of Asymptomatic and Peri-Urban Infections in Pregnant Women with Malaria

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Ana-María Vásquez ◽  
Lina Zuluaga-Idárraga ◽  
Margarita Arboleda ◽  
Luz-Yáned Usuga ◽  
Carolina Gallego-Marin ◽  
...  
Keyword(s):  
Antenatal Care ◽  
Pregnant Women ◽  
Cross Sectional Study ◽  
Malaria In Pregnancy ◽  
Limited Information ◽  
Cross Sectional ◽  
History Of ◽  
Placental Blood ◽  
Adverse Pregnancy ◽  
In Pregnancy

Background. Malaria in pregnancy (MiP) has been associated with adverse pregnancy outcomes. There is limited information on MiP in low transmission regions as Colombia. This study aimed to describe the epidemiology of MiP through active surveillance of infections by microscopy and polymerase chain reaction (PCR). Methods. A cross-sectional study was conducted between May 2016 and January 2017 in five municipalities (Apartadó, Turbo, El Bagre, Quibdó, and Tumaco) in Colombia. Pregnant women self-presenting at health centers for antenatal care visits, seeking medical care for suspected malaria, or delivery, were enrolled. Diagnosis of Plasmodium spp was made in peripheral and placental blood samples by microscopy and PCR. Results. A total of 787 pregnant women were enrolled; plasmodial infection was diagnosed by microscopy in 4.2% (95% CI 2.8-5.6; 33/787) or by nPCR in 5.3% (95% CI 3.8-6.9; 42/787) in peripheral blood. Most of the infections were caused by P. falciparum (78.5%), and 46% were afebrile (asymptomatic). Women in the first and second trimester of pregnancy were more likely to be infected (aOR=3.06, 95%CI=1.6−5.8). To live in the urban/peri-urban area (aOR=3.04, 95%CI=1.4−6.56), to have a history of malaria during last year (aOR=5.45, 95%IC=2.16−13.75), and the infrequent bed net usage (aOR=2.8, 95%CI=1.31−5.97) were associated with the infection. Pregnant infected women had a higher risk of anaemia (aOR=2.18, 95%CI=1.15−4.12) and fever (aOR=14.2, 95%CI=6.89−29.8). Conclusion. The screening for malaria during antenatal care in endemic areas of Colombia is highly recommended due to the potential adverse effects of Plasmodium spp. infection in pregnancy and as an important activity for the surveillance of asymptomatic infections in the control of malaria.

scholarly journals Malaria Detection using Polymerase Chain Reaction (PCR) Method in Pregnant Women’s Saliva on Several Hospitals in North Sulawesi Province

2016 ◽  
Author(s):  
Dewanto Khrisnamurti
Keyword(s):  
Pregnant Women ◽  
First Trimester ◽  
Cross Sectional Study ◽  
Malaria In Pregnancy ◽  
Cross Sectional ◽  
North Sulawesi ◽  
Blood Smears ◽  
Pcr Method ◽  
Polymerase Chain ◽  
In Pregnancy

Objective: To detect malaria by PCR examination of saliva in pregnant women and to obtain the incidence of malaria and the type of plasmodium causing malaria in pregnant women at various hospital in North Sulawesi. Method: A descriptive cross sectional study in pregnant women during antenatal care at the Department of Obstetrics and Gynecology Faculty of Medicine University of Sam Ratulangi/Prof. Dr. R.D. Kandou General Hospital in Manado, R.W. Monginsidi Hospital in Manado, Bethesda Hospital in Tomohon, and Datoe Binangkang Hospital in Kotamobagu, from 1 April until 31 May 2008. Result: There were 43 pregnant women clinically diagnosed with malaria, 23 (53.49%) by PCR examination of saliva and 20 (46.59%) by blood smears. From 23 cases of malaria in pregnancy detected by PCR, there were 18 diagnosed as tropical malaria, 3 tertian malaria, and 2 mixed malaria. Conclusions: The incidence of malaria in pregnancy at various hospital in North Sulawesi using PCR methods for saliva examination from April 1 - May 31 2008 is 53.49%. In this study malaria are mostly caused by Plasmodium falciparum with the largest incidence in primigravida, in the first trimester. [Indones J Obstet Gynecol 2012; 36-1:14-9] Keywords: malaria, PCR, pregnancy, saliva

scholarly journals Prevalence and Associated Factors of Self-Medication among Pregnant Women on Antenatal Care Follow-Up at University of Gondar Comprehensive Specialized Hospital in Gondar, Northwest Ethiopia: A Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Faisel Dula Sema ◽  
Deres Gezahegn Addis ◽  
Eshetie Azezew Melese ◽  
Demeke Dana Nassa ◽  
Zemene Demelash Kifle
Keyword(s):  
Antenatal Care ◽  
Pregnant Women ◽  
Previous History ◽  
Cross Sectional Study ◽  
Monthly Income ◽  
Self Medication ◽  
Cross Sectional ◽  
Specialized Hospital ◽  
History Of

Background. Self-medication is being prevalent throughout the globe. Although pregnant women are among the most vulnerable group of the population for drug-induced adverse effects on their fetus and themselves, many pregnant women use self-medication without adequate safety precautions. Objective. This study was aimed at assessing the prevalence and associated factors of self-medication among pregnant women on antenatal care follow-up at University of Gondar Comprehensive Specialized Hospital. Methods. A cross-sectional study was employed among 400 pregnant women attending antenatal care clinic at the University of Gondar Comprehensive Specialized Hospital between February 01 and May 30, 2019. A structured interviewer-administered questionnaire was used for data collection. Data were analyzed using SPSS® (IBM Corporation) version 22. Descriptive statistics were presented using frequency and proportion. Binary logistic regression was used to identify factors associated with self-medication with a 95% confidence level and p value of 0.05. Results. Among 400 respondents, the prevalence of self-medication during the current pregnancy was 44.8% (95% CI=40.5-50). Among all respondents (400), 38.0% (95% CI=33.3-42.8) and 12.5% (95% CI=9.5-15) used herbal and conventional medicine, respectively. Self-medication showed a significant association with a previous history of self-medication and monthly income. Conclusions. The prevalence of self-medication among pregnant women is considerably high. The previous history of self-medication and monthly income showed a significant association with self-medication. Awareness creation should be done for reproductive-age women on the potential risks of self-medication.

scholarly journals Intermittent preventive treatment comparing two versus three doses of sulphadoxine pyrimethamine (IPTp-SP) in the prevention of anaemia in pregnancy in Ghana: A cross-sectional study

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250350
Author(s):  
Yaa Nyarko Agyeman ◽  
Sam Newton ◽  
Raymond Boadu Annor ◽  
Ellis Owusu-Dabo
Keyword(s):  
Antenatal Care ◽  
Pregnant Women ◽  
Intermittent Preventive Treatment ◽  
Preventive Treatment ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Anaemia In Pregnancy ◽  
Sulphadoxine Pyrimethamine ◽  
In Pregnancy

In 2012 the World Health Organisation (WHO) revised the policy on Intermittent Preventive Treatment with Sulphadoxine Pyrimethamine (IPTp-SP) to at least three doses for improved protection against malaria parasitaemia and its associated effects such as anaemia during pregnancy. We assessed the different SP dosage regimen available under the new policy to determine the dose at which women obtained optimal protection against anaemia during pregnancy. A cross-sectional study was conducted among pregnant women who attended antenatal clinic at four different health facilities in Ghana. The register at the facilities served as a sampling frame and simple random sampling was used to select all the study respondents; they were enrolled consecutively as they kept reporting to the facility to receive antenatal care to obtain the required sample size. The haemoglobin level was checked using the Cyanmethemoglobin method. Multivariable logistic regression was performed to generate odds ratios, confidence intervals and p-values. The overall prevalence of anaemia among the pregnant women was 62.6%. Pregnant women who had taken 3 or more doses of IPTp-SP had anaemia prevalence of 54.1% compared to 66.6% of those who had taken one or two doses IPTp-SP. In the multivariable logistic model, primary (aOR 0.61; p = 0.03) and tertiary education (aOR 0.40; p = <0.001) decreased the odds of anaemia in pregnancy. Further, pregnant women who were anaemic at the time of enrollment (aOR 3.32; p = <0.001) to the Antenatal Care clinic and had malaria infection at late gestation (aOR 2.36; p = <0.001) had higher odds of anaemia in pregnancy. Anaemia in pregnancy remains high in the Northern region of Ghana. More than half of the pregnant women were anaemic despite the use of IPTp-SP. Maternal formal education reduced the burden of anaemia in pregnancy. The high prevalence of anaemia in pregnancy amid IPTp-SP use in Northern Ghana needs urgent attention to avert negative maternal and neonatal health outcomes.

scholarly journals Magnitude and Predictors of Antenatal Depression among Pregnant Women Attending Antenatal Care in Sodo Town, Southern Ethiopia: Facility-Based Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Bekalu Thomas Chuma ◽  
Getu Gamo Sagaro ◽  
Feleke Hailemichael Astawesegn
Keyword(s):  
Antenatal Care ◽  
Pregnant Women ◽  
Previous History ◽  
Educational Status ◽  
Antenatal Depression ◽  
Cross Sectional Study ◽  
Obstetric Complications ◽  
Southern Ethiopia ◽  
Cross Sectional ◽  
History Of

Background. Depression affects approximately 10 to 20% of pregnant women globally, and one in ten and two in five women in developed and developing countries develop depression during pregnancy, respectively. However, evidence regarding its magnitude and predictors in Southern Ethiopia is limited. The present study is aimed at assessing the magnitude and predictors of antenatal depression among pregnant women attending antenatal care in Sodo town. Methods. A facility-based cross-sectional study was conducted among 403 antenatal care attendants in Sodo town from November 2 to January 30, 2017. Systematic random sampling was used to select the study population, and data were collected by using a pretested and structured questionnaire. Data were entered using Epi-data 4.2 and then exported and analyzed using SPSS version 20. Bivariate and multivariable logistic regression analyses were used to assess the association between the dependent variable and independent variables. Variables with P value less than 0.05 were considered as statistically significant. Results. A total of 400 pregnant women were interviewed. The magnitude of antenatal depression was 16.3% (95% CI (12.8%, 19.9%)). Husband’s educational status, at the college and above (AOR: 0.09; 95% CI (0.03, 0.34), regular exercise (AOR: 0.16; 95% CI (0.07, 0.36)), planned pregnancy (AOR: 0.16; 95% CI (0.06, 0.44)), use of family planning (AOR: 0.31; 95% CI (0.14, 0.66)), previous history of anxiety (AOR: 2.96; 95% CI (1.30, 6.74)), previous history of obstetric complications (AOR: 19.03; 95% CI (5.89, 61.47)), and current obstetric complications (AOR: 30.38; 95% CI (3.14, 294.19)) were significant predictors of antenatal depression. Conclusion. Nearly one in six pregnant women had antenatal depression. The husband’s educational status, regular exercise, planned pregnancy, use of family planning, previous history of anxiety, previous history of obstetric complications, and current history of obstetric complications were significant predictors of antenatal depression. Screening for depression during routine antenatal care could be essential and recommended to identify early and prevent further morbidities and mortalities due to antenatal depression.

scholarly journals Prevalence and predictors of Toxoplasma gondii infection in pregnant women from Dhamar, Yemen

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Abdulelah H. Al-Adhroey ◽  
Amat Al-Khaleq O. Mehrass ◽  
Abdulqawi A. Al-Shammakh ◽  
Abdullatif D. Ali ◽  
Mohammed Y. M. Akabat ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
Pregnant Women ◽  
Spontaneous Abortion ◽  
Parasitic Infection ◽  
Cross Sectional Study ◽  
Immunoglobulin M ◽  
Cross Sectional ◽  
Igm Antibodies ◽  
History Of ◽  
Adverse Pregnancy

Abstract Background Toxoplasmosis is a common and serious parasitic infection caused by the ubiquitous obligatory intracellular protozoan organism, Toxoplasma gondii. Although infection with T. gondii is usually asymptomatic in healthy individuals, it can lead to severe pathological effects in congenital cases and immunocompromised patients. This study aimed to determine the seroprevalence of T. gondii and its predictors among pregnant women seeking prenatal and medical care at the general maternal and child health facility in Dhamar district of Dhamar governorate, Yemen. Methods A total of 420 pregnant women were randomly selected for this cross-sectional study. Participants were screened for anti-T. gondii antibodies (i.e. immunoglobulin M; IgM and immunoglobulin G; IgG) using electrochemiluminescence immunoassay. Demographic, socioeconomic, obstetric and behavioural data were collected using a pretested questionnaire via face-to-face interview. Univariate and multivariate analyses were used to identify the independent predictors of T. gondii seroprevalence. Results The overall seroprevalence of anti-T. gondii antibodies (IgG and/or IgM) among the participants was 21.2% (89/420; 95% CI = 17.3–25.1). Anti-T. gondii IgG antibodies were detected in 20.0% (84/420) of the women of which 12.9% (54/420) were positive for only IgG and 7.1% (30/420) were positive for both IgG and IgM antibodies. Moreover, 5 women (1.2%) were reactive only for IgM antibodies. Significant associations between T. gondii seroprevalence and history of spontaneous abortion (P <  0.001), raw vegetables consumption (P = 0.036), and presence of cats in household (P = 0.049) were reported. Multivariate analysis confirmed that history of spontaneous abortion (AOR = 4.04; 95% CI = [2.46, 6.63]) and presence of cats in household (AOR = 1.77; 95% CI = [1.02, 3.07]) are significant predictors of T. gondii seroprevalence among the studied participants. Conclusion The study found a high seroprevalence (21.2%) of T. gondii infection during pregnancy in Dhamar district, which is significantly associated with adverse pregnancy outcomes. The provision of adequate maternal healthcare and health education pertaining to the prevention of T. gondii infection is therefore imperative to curtail the prevalence of infection among the studied population.

scholarly journals Ocular pathologies emerging in pregnancy.

2019 ◽  
Vol 26 (09) ◽  
pp. 1457-1460
Author(s):  
Arif Hussain ◽  
Kishwar Naheed ◽  
Nasir Mahmood
Keyword(s):  
Pregnant Women ◽  
Systemic Disease ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Co Morbidity ◽  
Department Of Ophthalmology ◽  
History Of ◽  
Systemic Examination ◽  
Study Setting ◽  
In Pregnancy

Objectives: To determine ocular pathologies that appear in pregnant women with no history of ocular or systemic disease prior to conception. Study Design: Cross-sectional study. Setting: Department of Ophthalmology in association with Department of Gynecology, Pak Red Crescent Medical and Dental College Dina Nath District Kasur. Period: January 2018 to April 2018. Materials and Methods: One hundred and twenty pregnant females with no history of previous ocular or systemic co morbidity were included in study. After obtaining informed consent detailed ocular and medical history was taken and complete ocular examination was done. Results: Mean age of the participant female was 24.7 years (Range 19- 40 years). Four of them (3.33%) had bilateral optic disc edema, 2 of them had central serous chorioretinopathy (CSCR) and one female had unilateral macular hole. Conclusions: Ocular pathologies emerging in pregnancy are not uncommon and should not be overlooked. Pregnant women with ocular complaints should undergo a thorough ocular and systemic examination along with necessary investigations so that the pathological eye changes and associated systemic diseases could be managed timely and properly.

scholarly journals Patterns OF Prevention OF Malaria in Pregnancy Among Pregnant Women at Selected Antenatal Care Facilities, Ilishan-Remo, Ogun State, Nigeria

2021 ◽  
Vol 4 (2) ◽  
pp. 105-128
Author(s):  
Ogungbesan O.F. ◽  
Okafor N.A. ◽  
Ogungbesan J.O.
Keyword(s):  
Pregnant Women ◽  
Tertiary Education ◽  
Sampling Technique ◽  
Malaria Prevention ◽  
Cross Sectional Study ◽  
Malaria In Pregnancy ◽  
Chi Square ◽  
Cross Sectional ◽  
Ogun State ◽  
In Pregnancy

Malaria in pregnancy is a preventable infectious disease, yet it remains the cause of maternal, in-utero morbidity and mortality. Pregnant women adopt different patterns of prevention against malaria occurrences and complications. This study aims to identify patterns of malaria prevention among pregnant women inIlishan Remo, Ogun State. In a descriptive cross-sectional study, a purposive sampling technique was used to proportionately select 271 pregnant women attending Ante-natal care (ANC) facilities. A self-administered questionnaire was used to obtained information on 56 items. Data were collected on clinic days for eight weeks duration and analyzed with SPSS 23 (for descriptive frequencies and percentages) and hypotheses tested with chi-square at p ≤ 0.005. One-third (35.4%) of the pregnant women aged 31-35years. Predominantly, 80.8% of the women were Christians, almost half (49.1%) had tertiary education. The mean of preventive measures used by pregnant women was 27.16±0.25. Slightly half (52.4%) always net windows and doors, 38.4% always and 53.4% often cleared bushes around house respectively. About 30.3% of pregnant women often used IPT-SP and 19.9% used direct observation therapy (DOT). On the categorized prevention patterns, half (54.2%) used conventional and 6.64% non-conventional. There was a significant relationship between the patterns of prevention and ANC facilities (χ2 =20.291), beliefs (χ2 = 16.540) at p< 0.005. The patterns of conventional and non-conventional prevention were used by pregnant women. However, pregnant women should be advised to use the recommended FMOH/WHO standard malaria prevention for safety.

scholarly journals Faktor-faktor yang Mempengaruhi Self Care Agency pada Ibu Hamil dengan Preeklampsia

2019 ◽  
Vol 11 (4) ◽  
pp. 289-294
Author(s):  
Apolonia Antonilda Ina ◽  
Veronika Ririn Marwaningsih
Keyword(s):  
Antenatal Care ◽  
Pregnant Women ◽  
Self Care ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Total Correlation ◽  
History Of ◽  
Care Agency ◽  
In Pregnancy

Kematian ibu akibat hipertensi dalam kehamilan dapat dicegah dengan deteksi dini terjadinya peningkatan tekanan darah melalui antenatal care yang berkualitas. Preeklampsia masih menjadi masalah yang belum terselesaikan karena angka kejadian yang masih tinggi dan komplikasi kematian ibu dan anak yang terjadi. Hal ini menjadikan studi tentang preklampsia masih sangat dibutuhkan dengan harapan bisa memberikan kontribusi data untuk penelitian lanjutan. studi tentang self  agency pada ibu hamil dengan preeklampsia belum pernah dilakukan di Indonesia. Self agency yang kuat akan memberikan kontribusi ibu hamil dalam mencegah terjadinya komplikasi akibat preeklampsia. Tujuan penelitian yaitu menganalisis faktor-faktor yang mempengaruhi self care agency pada  ibu hamil dengan preeklampsia. Desain penelitian yaitu  cross sectional. Penelitian dilaksanakan pada bulan Juli sampai September 2019. Sampel pada penelitian ini  yaitu ibu-ibu hamil yang berada di Rumah Sakit dan Praktik Bidan Mandiri sebanyak 90 responden. Proses pengumpulan data yaitu responden mengisi kuesioner yang diberikan peneliti. Kuesioner tersebut telah dilakukan uji validitas dan reliabilitas dibuktikan dengan nilai corrected item-total correlation > 0,3 serta  nilai Cronbach alpha > 0,6. Data yang telah diperoleh kemudian dianalisis menggunakan uji chi square serta  regresi logistik. Hasil penelitian didapatkan tidak ada hubungan antara usia, paritas, riwayat keluarga, pekerjaan, pendidikan, frekuensi ANC dengan kejadian preeklampsia dengan p value > 0,05. Riwayat hipertensi merupakan faktor risiko preeklampsia. Bagi peneliti selanjutnya disarankan untuk menambah jumlah sampel dan melakukan analisis lebih lanjut mengenai faktor-faktor yag belum diteliti, seperti riwayat preeklampsia, jarak kelahiran, usia gestasi.  Kata kunci: AKI, preeklampsia, self care agency MULTIPLE FACTORS OF SELF CARE AGENCY IN PREGNANCY WOMEN WITH PREECLAMPSIA   ABSTRACT Maternal mortality due to hypertension in pregnancy can be prevented by early detection of increased blood pressure through quality antenatal care. Preeclampsia is still an unsolved problem because of the high incidence and complications of maternal and child deaths that occur. This makes the study of preeclampsia still very much needed in the hope that it can contribute data for further research. a study of self agency in pregnant women with preeclampsia has never been done in Indonesia. A strong self agency will contribute to pregnant women in preventing complications due to preeclampsia. The research objective was to analyze the factors that influence the self care agency in pregnant women with preeclampsia. The study design was cross sectional. The study was conducted in July to September 2019. Samples in this study were pregnant women who were in the Hospital and the Practice of Independent Midwives as many as 90 respondents. The process of collecting data is that respondents fill out questionnaires given by researchers. The questionnaire was tested for validity and reliability as evidenced by the corrected item-total correlation> 0.3 and Cronbach alpha> 0.6. The data obtained were then analyzed using the chi square test and logistic regression. The results showed there was no relationship between age, parity, family history, work, education, frequency of ANC with the incidence of preeclampsia with p value> 0.05. A history of hypertension is a risk factor for preeclampsia. Further researchers are advised to increase the number of samples and conduct further analysis of factors that have not been studied, such as a history of preeclampsia, birth spacing, gestational age.  Keywords: Maternal Mortality Rate, preeclampsia, self care agency

Quantifying Pregnant Women’s Knowledge of Educational Components of Antenatal Care in Lesotho

2019 ◽  
Vol 21 (1) ◽  
Author(s):  
Tabeta Seeiso ◽  
Mamutle M. Todd-Maja
Keyword(s):  
Antenatal Care ◽  
Maternal Mortality ◽  
Pregnant Women ◽  
Rural Areas ◽  
Geographic Location ◽  
Sub Saharan Africa ◽  
World Health ◽  
Cross Sectional ◽  
Danger Signs ◽  
In Pregnancy

Antenatal care (ANC) literacy is particularly important for pregnant women who need to make appropriate decisions for care during their pregnancy and childbirth. The link between inadequate health literacy on the educational components of ANC and maternal mortality in sub-Saharan Africa (SSA) is undisputable. Yet, little is known about the ANC literacy of pregnant women in SSA, with most studies inadequately assessing the four critical components of ANC literacy recommended by the World Health Organization, namely danger signs in pregnancy; true signs of labour; nutrition; and preparedness for childbirth. Lesotho, a country with one of the highest maternal mortality rates in SSA, is also underexplored in this research area. This cross-sectional study explored the levels of ANC literacy and the associated factors in 451 purposively sampled women in two districts in Lesotho using a structured questionnaire, making recourse to statistical principles. Overall, 16.4 per cent of the participants had grossly inadequate ANC literacy, while 79.8 per cent had marginal levels of such knowledge. The geographic location and level of education were the most significant predictors of ANC literacy, with the latter variable further subjected to post hoc margins test with the Bonferroni correction. The participants had the lowest scores on knowledge of danger signs in pregnancy and true signs of labour. Adequate ANC literacy is critical to reducing maternal mortality in Lesotho. Improving access to ANC education, particularly in rural areas, is recommended. This study also provides important recommendations critical to informing the national midwifery curriculum.

scholarly journals The association between subclinical hypothyroidism and TPOAb positivity with infertility in a population-based study: Tehran thyroid study (TTS)

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Batul Birjandi ◽  
Fahimeh Ramezani Tehrani ◽  
Atieh Amouzegar ◽  
Maryam Tohidi ◽  
Razieh Bidhendi Yarandi ◽  
...  
Keyword(s):  
Thyroid Autoimmunity ◽  
Population Based ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Population Based Study ◽  
History Of ◽  
Autoimmune Condition ◽  
Biochemical Measurements ◽  
Adverse Pregnancy ◽  
Adjusted Logistic Regression

Abstract Background Thyroid autoimmunity(TAI) is the most prevalent autoimmune condition in women of fertile age. There are increasing data regarding the association of thyroid dysfunction and thyroid autoimmunity with adverse pregnancy outcomes but there is no consensus regarding infertility and TPOAb positivity; thus we aimed to evaluate the association between thyroid TPOAb positivity and infertility in females and males in a population-based study (TTS). Methods Cross-sectional study of 3197 female and male participants in Tehran Thyroid Study (TTS) at the framework of the Tehran Lipid and Glucose Study (TLGS). Data included biochemical measurements and a self-administered questionnaire. Results A total of 12,823 cases in phase 4, 3719 cases (2108 female and 1611 male) were analyzed. The mean TSH of the infertile female and male was 2.52 ± 2.68 μIU/ml and 3.24 ± 10.26 μIU/ml respectively. The TPO median(IQR) of women with and without a history of infertility were 6.05 (3.30–13.96)and 6.04 (3.17–11.15);(P = 0.613), they were 5.08 (3.20–125.68) and 5.31 (3.93–125.68);(P = 0.490) in male participants, respectively. Results of crude and adjusted logistic regression analysis of the development of infertility by thyroid function and TPOAb, except for fT4 in male subjects, depicted no association between infertility and other variables in both crude and adjusted models. Conclusion Based on the result, thyroid autoimmunity was not associated with infertility in both females and males.

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