scholarly journals Extraskeletal Myxoid Chondrosarcoma: Long-Term Survival in the Setting of Metastatic Disease

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Karim Masrouha ◽  
Iqbal Multani ◽  
Om Bhatt ◽  
Michelle Ghert
Keyword(s):  
Pulmonary Metastases ◽  
Extraskeletal Myxoid Chondrosarcoma ◽  
Term Survival ◽  
Long Term Survival ◽  
Myxoid Chondrosarcoma ◽  
Systemic Intervention ◽  
Slow Progression ◽  
Close Observation ◽  
History Of

Three cases of extraskeletal myxoid chondrosarcoma (EMC) in patients who presented with pulmonary metastases and were managed with long-term close observation without systemic intervention are presented. Follow-up imaging showed slow progression of their disease over several years, and the patients remained asymptomatic from their pulmonary metastases. This clinical experience provides insight into the natural history of the disease and suggests that some patients may experience long-term survival and remain asymptomatic even without systemic intervention, thereby improving their quality of life by avoiding potentially debilitating treatments.

A case report of long-term survival of metastatic extraskeletal myxoid chondrosarcoma treated with surgery and hypofractionated radiotherapy

2014 ◽  
Vol 13 (4) ◽  
pp. 493-497
Author(s):  
Haoming Qiu ◽  
Mary Hare ◽  
Yuhchyau Chen
Keyword(s):  
Case Report ◽  
Surgical Excision ◽  
Hypofractionated Radiotherapy ◽  
Extraskeletal Myxoid Chondrosarcoma ◽  
Term Survival ◽  
Myxoid Chondrosarcoma ◽  
History Of ◽  
Locally Recurrent ◽  
Control Disease

AbstractWe describe the case of a patient with a 10-year history of metastatic extraskeletal myxoid chondrosarcoma (EMC), who underwent repeated surgical excision and ten courses of hypofractionated radiotherapy to locally recurrent or metastatic disease. We review the literature on EMC’s and propose that surgery and radiotherapy can be used to control disease progression and palliate symptoms for extended periods of time with acceptable toxicity profiles.

scholarly journals Long-term survival with multiple metastasectomies for pulmonary osteosarcoma: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Satoshi Takamori ◽  
Hiroyuki Oizumi ◽  
Jun Suzuki ◽  
Katsuyuki Suzuki
Keyword(s):  
Case Report ◽  
Pulmonary Metastases ◽  
Multidisciplinary Treatment ◽  
Underlying Disease ◽  
Pulmonary Metastasectomy ◽  
Extensive Resection ◽  
Term Survival ◽  
Long Term Survival ◽  
Primary Surgery

Abstract Background Repeat pulmonary metastasectomy (PM) considerably improves the prognosis of patients with pulmonary metastases of osteosarcoma. Reports have demonstrated a significantly improved prognosis in patients who have undergone repeat metastasectomy for osteosarcoma; however, there have been no reports with more than six metastasectomies. Herein, we describe the long-term survival of a patient following resection of multiple tumors and other treatments for metastatic osteosarcoma. Case presentation A 28-year-old woman underwent extensive resection and postoperative adjuvant chemotherapy for right tibial sarcoma. Over the years, she developed repeated pulmonary metastases. First, 116 metastases were removed from the bilateral lungs. After that, multiple PMs of approximately 250 tumors and other treatments for deep metastatic lesions were performed. The patient died of the underlying disease 24 years after the primary surgery. Conclusions This case report demonstrates the long-term survival benefit of a multidisciplinary treatment centered on multiple metastasectomies.

The influence of thrombophilia on the long-term survival of patients with a history of venous thromboembolism

2013 ◽  
Vol 109 (01) ◽  
pp. 79-84 ◽  
Author(s):  
Sylvia Reitter-Pfoertner ◽  
Thomas Waldhoer ◽  
Michaela Mayerhofer ◽  
Ernst Eigenbauer ◽  
Cihan Ay ◽  
...  
Keyword(s):  
Risk Factors ◽  
Venous Thromboembolism ◽  
Multivariable Analysis ◽  
Factor V Leiden ◽  
Arterial Disease ◽  
Factor V ◽  
Term Survival ◽  
Long Term Survival ◽  
History Of

SummaryData on the long-term survival following venous thromboembolism (VTE) are rare,and the influence of thrombophilia has not been evaluated thus far. Our aim was to assess thrombophilia-parameters as predictors for long-term survival of patients with VTE. Overall, 1,905 outpatients (99 with antithrombin-, protein C or protein S deficiency, 517 with factor V Leiden, 381 with elevated factor VIII and 160 with elevated homocysteine levels, of these 202 had a combination and 961 had none of these risk factors) were included in the study between September 1, 1994 and December 31, 2007. Retrospective survival analysis showed that a total of 78 patients (4.1%) had died during the analysis period, among those four of definite or possible pulmonary embolism and four of bleeding. In multivariable analysis including age and sex an association with increased mortality was found for hyperhomocysteinemia (hazard ratio 2.0 [1.1.-3.5]) whereas this was not the case for all other investigated parameters. We conclude that the classical hereditary thrombophilia risk factors did not have an impact on the long-term survival of patients with a history of VTE. Thus our study supports the current concept that thrombophilia should not be a determinant for decision on long term anticoagulation. However, hyperhomocysteinaemia, known as a risk factor for recurrent VTE and arterial disease, might impact survival.

scholarly journals Long-term outcomes in patients with critical limb ischemia and heart failure with preserved or reduced ejection fraction

2017 ◽  
Vol 22 (4) ◽  
pp. 307-315 ◽  
Author(s):  
Kavita B Khaira ◽  
Ellen Brinza ◽  
Gagan D Singh ◽  
Ezra A Amsterdam ◽  
Stephen W Waldo ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Critical Limb Ischemia ◽  
Limb Ischemia ◽  
Left Ventricular ◽  
Term Survival ◽  
Long Term Survival ◽  
Reduced Ejection Fraction ◽  
History Of

The impact of heart failure (HF) on long-term survival in patients with critical limb ischemia (CLI) has not been well described. Outcomes stratified by left ventricular ejection fraction (EF) are also unknown. A single center retrospective chart review was performed for patients who underwent treatment for CLI from 2006 to 2013. Baseline demographics, procedural data and outcomes were analyzed. HF diagnosis was based on appropriate signs and symptoms as well as results of non-invasive testing. Among 381 CLI patients, 120 (31%) had a history of HF and 261 (69%) had no history of heart failure (no-HF). Within the HF group, 74 (62%) had HF with preserved ejection fraction (HFpEF) and 46 (38%) had HF with reduced ejection fraction (HFrEF). The average EF for those with no-HF, HFpEF and HFrEF were 59±13% vs 56±9% vs 30±9%, respectively. The likelihood of having concomitant coronary artery disease (CAD) was lowest in the no-HF group (43%), higher in the HFpEF group (70%) and highest in the HFrEF group (83%) ( p=0.001). Five-year survival was on average twofold higher in the no-HF group (43%) compared to both the HFpEF (19%, p=0.001) and HFrEF groups (24%, p=0.001). Long-term survival rates did not differ between the two HF groups ( p=0.50). There was no difference in 5-year freedom from major amputation or freedom from major adverse limb events between the no-HF, HFpEF and HFrEF groups, respectively. Overall, the combination of CLI and HF is associated with poor 5-year survival, independent of the degree of left ventricular systolic dysfunction.

scholarly journals Long-term survival after surgery for pulmonary metastases from colorectal cancer: an observational cohort study

2017 ◽  
Vol 9 (11) ◽  
pp. 4358-4365 ◽  
Author(s):  
Mamdoh Al-Ameri ◽  
Michael Persson ◽  
Per Bergman ◽  
Anders Franco-Cereceda ◽  
Ulrik Sartipy
Keyword(s):  
Colorectal Cancer ◽  
Cohort Study ◽  
Pulmonary Metastases ◽  
Observational Cohort Study ◽  
Term Survival ◽  
Long Term Survival ◽  
Observational Cohort

Long-Term Survival After Repeated Resection of Pulmonary Metastases From Colorectal Cancer

2007 ◽  
Vol 84 (1) ◽  
pp. 203-210 ◽  
Author(s):  
Stefan Welter ◽  
Jan Jacobs ◽  
Thomas Krbek ◽  
Bettina Krebs ◽  
Georgios Stamatis
Keyword(s):  
Colorectal Cancer ◽  
Pulmonary Metastases ◽  
Term Survival ◽  
Long Term Survival

Long-term survival after resection of pulmonary metastases from carcinoma of the breast

1992 ◽  
Vol 54 (2) ◽  
pp. 244-248 ◽  
Author(s):  
Louis A. Lanza ◽  
Giri Natarajan ◽  
Jack A. Roth ◽  
Joe B. Putnam
Keyword(s):  
Pulmonary Metastases ◽  
Carcinoma Of The Breast ◽  
Term Survival ◽  
Long Term Survival

Does a History of Malignancy Affect Long-Term Survival in Heart Transplant Recipients?

2017 ◽  
Vol 36 (4) ◽  
pp. S226
Author(s):  
Y. Ravi ◽  
E.M. Stock ◽  
S.K. Lella ◽  
J.V. Balasubramaniyan ◽  
L.A. Nikloidis ◽  
...  
Keyword(s):  
Heart Transplant ◽  
Transplant Recipients ◽  
Term Survival ◽  
Long Term Survival ◽  
History Of ◽  
Heart Transplant Recipients
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