scholarly journals Suspected Radiation-Induced Osteosarcoma in a Domestic Shorthair Cat

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Natalie Swieton ◽  
Stephanie G. Nykamp ◽  
Valérie J. Poirier ◽  
Shannon Wainberg ◽  
Michelle L. Oblak
Keyword(s):  
Radiation Therapy ◽  
Metastatic Disease ◽  
Spindle Cell ◽  
Late Complication ◽  
Acute Onset ◽  
Cell Tumour ◽  
Disease Development ◽  
Radiation Induced ◽  
Spindle Cell Tumour ◽  
Chondroblastic Osteosarcoma

A 3-year-old, male neutered domestic shorthair cat, presented for acute onset tail paresis. He was diagnosed with a spindle cell tumour at the level of L7-CD1 and treated with course fractionation radiation therapy. Three years following radiation therapy, the cat developed chondroblastic osteosarcoma of the pelvis, suspected to be secondary to radiation therapy. Hemipelvectomy was performed and the cat was treated with radiation therapy for remaining gross disease. The cat was euthanized 127 days post-operatively due to suspected metastatic disease. Development of radiation-induced tumours should be considered as a rare late complication in cats undergoing radiation therapy.

Primary pulmonary hyalinising spindle cell tumour with giant rosettes

Pathology ◽  
2014 ◽  
Vol 46 (5) ◽  
pp. 451-453
Author(s):  
Karen Whale ◽  
Genevieve Bennett
Keyword(s):  
Spindle Cell ◽  
Cell Tumour ◽  
Spindle Cell Tumour

A spindle cell tumour in the bladder

2020 ◽  
Vol 26 (7) ◽  
pp. 337-339
Author(s):  
Jon Griffin ◽  
Ban Jalil
Keyword(s):  
Spindle Cell ◽  
Cell Tumour ◽  
Spindle Cell Tumour

scholarly journals A regressing spindle cell tumour of Reed

2017 ◽  
pp. bcr-2017-222002
Author(s):  
Simon Tso ◽  
William Hunt ◽  
Joanna E Gach
Keyword(s):  
Spindle Cell ◽  
Cell Tumour ◽  
Spindle Cell Tumour

Novel TFG – RET fusion in a spindle cell tumour with S100 and CD34 coexpresssion

2019 ◽  
Vol 76 (2) ◽  
pp. 333-336 ◽  
Author(s):  
Shihleone Loong ◽  
Derrick W Q Lian ◽  
Chik H Kuick ◽  
Tse H Lim ◽  
Shireen A Nah ◽  
...  
Keyword(s):  
Spindle Cell ◽  
Cell Tumour ◽  
Spindle Cell Tumour

Rare and unusual spindle cell tumour

2019 ◽  
Vol 73 (8) ◽  
pp. 526-526
Author(s):  
Harumi Nakamura ◽  
Masanori Kitamura ◽  
Hiroko Murata ◽  
Shuhei Kida ◽  
Jun Ishikawa ◽  
...  
Keyword(s):  
Spindle Cell ◽  
Cell Tumour ◽  
Spindle Cell Tumour

High Incidence of Radiation Induced Cavernous Hemangioma (RICH) in Long Term Survivors Who Underwent BMT with Radiation Therapy During Childhood or Adolescence.

Blood ◽  
2009 ◽  
Vol 114 (22) ◽  
pp. 4292-4292
Author(s):  
Takashi Koike ◽  
Noriharu Yanagimachi ◽  
Hiromasa Yabe ◽  
Miharu Yabe ◽  
Tsuyoshi Morimoto ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Cavernous Hemangioma ◽  
Late Complication ◽  
Weighted Image ◽  
Primary Disease ◽  
High Incidence ◽  
Radiation Induced ◽  
Long Term Survivors ◽  
The Brain

Abstract Abstract 4292 INTRODUCTION Radiation induced cavernous hemangioma (RICH) is a late complication of cerebral radiation therapy. An increased number of long term surviving blood and marrow transplantation (BMT) recipients have recovered from their primary disease but are at risk of RICH. METHODS We investigated 66 patients who underwent BMT during childhood or adolescence. We evaluated RICH numbers, size, location and their annual changes. Furthermore we developed scoring system of RICH in order to classify severity. MRI of the brain was performed annually for 5 to 27 years after BMT, including gradient-echo sequence (T2* weighted image). RICH SCORE 1-4 is designated as mild, 5-9 as moderate and 10 or more as severe. RESULTS Twenty-five patients (37.9%) was diagnosed RICH. The age at the time of the diagnosis was 11-40 years old (median 27 years old). The age at the time of BMT was 1-22 years old (median 9 years old). The period from BMT to diagnosis was 10-24 years (median 16 years). All cases received TBI as conditioning of BMT and/or cranial radiation (CR) prior to BMT as treatment of primary disease. RICH was found in 25/48 (52%) who received TBI and/or CR, and was not found in any of 18 patients without radiation therapy to the brain. Total dose to the brain was 10-36 Gy. Clinical manifestations were present only in four cases. RICH SCORE ranged 1-18 points (median 4 points). Small RICHs tended to be recognized only by T2* weighted image, but not by routine imaging methods. Classification of the severity was mild in 13 patients, moderate in 8 patients and severe in 4 patients. Severity was correlated with higher radiation dose and/or with younger ages at transplantation. RICH SCORE increased yearly in 7 of 25 patients. One case developed giant RICH more than 40mm as shown in the attached image. CONCLUSION High incidence of RICH was found in long term survivors who underwent BMT with radiation therapy. Since all of those patients did not show RICH before BMT and all positive patients had a history of radiation therapy to the brain, the cause of RICH in those patients was considered to be radiation. Careful and long term evaluation with MRI including T2* weighted image is necessary in BMT recipients who received radiation therapy prior and/or during BMT. Disclosures: Ando: Alexion: Research Funding.

Hyalinising spindle cell tumour with giant rosettes: report of a case with unusual features including original histological and ultrastructural observations

Pathology ◽  
2001 ◽  
Vol 33 (1) ◽  
pp. 101-107 ◽  
Author(s):  
Richard A. Scolyer ◽  
Stanley W. Mccarthy ◽  
Edward J. Wills ◽  
Allan A. Palmer
Keyword(s):  
Spindle Cell ◽  
Cell Tumour ◽  
Spindle Cell Tumour

Spindle cell tumour with glandular elements: an unusual ileal neoplasm

2009 ◽  
Vol 62 (6) ◽  
pp. 555-557
Author(s):  
A C Bateman ◽  
K Holgate ◽  
B Green ◽  
K Thway ◽  
J Primrose
Keyword(s):  
Spindle Cell ◽  
Cell Tumour ◽  
Spindle Cell Tumour

Solitary fibrous tumour: An unusual spindle cell tumour in the breast

Pathology ◽  
2018 ◽  
Vol 50 ◽  
pp. S77
Author(s):  
Nicholas Wee Chong Koh ◽  
Manish Mahadeorao Bundele
Keyword(s):  
Spindle Cell ◽  
Solitary Fibrous Tumour ◽  
Cell Tumour ◽  
Spindle Cell Tumour

The visual evoked potential can save sight in patients with radiation-induced optic neuropathy

2021 ◽  
pp. 112067212110491
Author(s):  
Ali Nouraeinejad
Keyword(s):  
Radiation Therapy ◽  
Diagnostic Test ◽  
Optic Neuropathy ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Vision Loss ◽  
Late Complication ◽  
Clinical Signs ◽  
Radiation Induced ◽  
Visual Evoked

Radiation-induced optic neuropathy (RION) is a late complication of radiation therapy for brain and skull base tumors. RION leads to the devastating total vision loss in one or both eyes. Therefore, the early detection of RION is vital. Since visual symptoms and clinical signs of RION are not present at early stages of the radiation injury, it is essential to apply a diagnostic test to detect RION as early as possible in order to start therapeutic interventions. The author proposes to apply visual evoked potential (VEP) as a diagnostic test in the interval time after radiation therapy.

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