scholarly journals Cobalt-Salen Catalyzed Electroreductive Alkylation of Activated Olefins

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Sylvie Condon ◽  
Céline Cannes ◽  
Fethi Bedioui
Keyword(s):  
Electrochemical Cell ◽  
Bond Formation ◽  
Iron Complex ◽  
Alkyl Halides ◽  
Sacrificial Anode ◽  
Mild Conditions ◽  
Regioselective Alkylation ◽  
Reported Study ◽  
One Step ◽  
Activated Olefins

Cobalt-Salen mediated electroreductive and regioselective alkylation of electron deficient olefins is reported in one step in an undivided electrochemical cell, in the presence of an iron rod as sacrificial anode. Although the reactivity depends on the class of alkyl halides, the reported study offers a green and expeditious electrosynthetic route for Csp3-Csp3 bond formation in mild conditions. This study also confirms the possible formation of the heterobinuclear cobalt-Salen-iron complex previously reported as the effective catalyst.

Convenient amidation of carboxyl group of carboxyphenylboronic acids

2016 ◽  
Vol 0 (0) ◽  
Author(s):  
Julia Nowak-Jary
Keyword(s):  
Bond Formation ◽  
Amide Bond ◽  
Protecting Groups ◽  
Nucleophilic Attack ◽  
Carboxyl Groups ◽  
Coupling Reagents ◽  
Mild Conditions ◽  
Amide Bond Formation ◽  
One Step ◽  
New Compounds

AbstractThe use of catalysts in the activation of carboxyl groups towards nucleophilic attack and the protection of other functional groups by suitable protecting groups are standard and necessary procedures in amide bond formation. In contrast to the usual methods, various new compounds, amides of APTES ((3-aminopropyl)triethoxysilane, 3-triethoxysilylpropylamine) and carboxyphenylboronic acids, as well as the amides of aniline and carboxyphenylboronic acids, were obtained in good yields by a one-step synthesis under mild conditions without using any coupling reagents or additional catalysts.

Copper-Catalyzed Intermolecular Thioamination of Maleimides with Thiols and Formamides: A One-Step Construction of 3-Amino-4-thiomaleimides Using Formamides as Nitrogen Sources

Synthesis ◽  
2018 ◽  
Vol 50 (23) ◽  
pp. 4627-4636 ◽  
Author(s):  
Sheng-Yin Zhao ◽  
Zhen-Hua Yang ◽  
Jia-Nan Zhu ◽  
Ze-Hui Jin ◽  
Jian Zheng
Keyword(s):  
Functional Group ◽  
Bond Formation ◽  
Nitrogen Sources ◽  
Diverse Range ◽  
Mild Conditions ◽  
Highly Efficient ◽  
One Step ◽  
Operational Simplicity

A highly efficient copper-catalyzed intermolecular C(sp2)–H thioamination of maleimides with thiols and formamides in the presence of fluoroboric acid is reported using various readily available formamides as nitrogen sources and solvents. A diverse range of 3-amino-4-thiomaleimides is obtained with good yields under mild conditions, involving C–N and C–S bond formation. This methodology enriches current C–N and C–S bond formation chemistry and features operational simplicity and excellent functional-group tolerance.

Design and Development of Fe-Catalyzed Intra- and Intermolecular Carbofunctionalization of Vinyl Cyclopropanes

2019 ◽  
Author(s):  
Lei Liu ◽  
Wes Lee ◽  
Mingbin Yuan ◽  
Chris Acha ◽  
Michael B. Geherty ◽  
...  
Keyword(s):  
Bond Formation ◽  
Cross Coupling ◽  
Alkyl Halides ◽  
Grignard Reagents ◽  
Mechanistic Studies ◽  
Radical Intermediates ◽  
Design And Implementation ◽  
Solvent Cage ◽  
Radical Cascade ◽  
Radical Processes

Design and implementation of the first (asymmetric) Fe-catalyzed intra- and intermolecular difunctionalization of vinyl cyclopropanes (VCPs) with alkyl halides and aryl Grignard reagents has been realized via a mechanistically driven approach. Mechanistic studies support the diffusion of the alkyl radical intermediates out of the solvent cage to participate in an intra- or -intermolecular radical cascade with the VCP followed by re-entering the Fe radical cross-coupling cycle to undergo selective C(sp2)-C(sp3) bond formation. Overall, we provide new design principles for Fe-mediated radical processes and underscore the potential of using combined computations and experiments to accelerate the development of challenging transformations.

One-step fabrication of Pd-embedded hierarchically porous carbon micro-spheres for formaldehyde removal under mild conditions

2021 ◽  
Author(s):  
Zhigang Ren ◽  
peng zhao ◽  
Ye Zhang ◽  
Yang Yu ◽  
xiaoxuan lv ◽  
...  
Keyword(s):  
Porous Carbon ◽  
Carbon Microspheres ◽  
Carbon Spheres ◽  
Pickering Emulsions ◽  
Hierarchically Porous ◽  
Mild Conditions ◽  
Formaldehyde Removal ◽  
One Step

Micron-sized carbon spheres synthesized via pickering emulsions has attracted much attention in recent two years. In present paper, we prepared palladium (Pd) and nitrogen co-embedded carbon microspheres for formaldehyde (HCHO)...

scholarly journals Continuous-Flow Processes for the Production of Floxacin Intermediates: Efficient C–C Bond Formation through a Rapid and Strong Activation of Carboxylic Acids

2020 ◽  
Vol 02 (03) ◽  
pp. e128-e132
Author(s):  
Shao-Zheng Guo ◽  
Zhi-Qun Yu ◽  
Wei-Ke Su
Keyword(s):  
Reaction Time ◽  
Continuous Flow ◽  
Flow System ◽  
Bond Formation ◽  
Product Yield ◽  
Raw Material ◽  
Material Consumption ◽  
Tank Reactor ◽  
Mild Conditions ◽  
Flow Processes

AbstractThe development of highly efficient C–C bond formation methods for the synthesis of ethyl 2-(2,4-dichloro-5-fluorobenzoyl)-3-(dimethylamino)acrylate 1 in continuous flow processes has been described, which is based on the concept of rapid and efficient activation of carboxylic acid. 2,4-Dichloro-5-fluorobenzoic acid is rapidly converted into highly reactive 2,4-dichloro-5-fluorobenzoyl chloride by treating with inexpensive and less-toxic solid bis(trichloromethyl)carbonate. And then it rapidly reacts with ethyl 3-(dimethylamino)acrylate to afford the desired 1. This process can be performed under mild conditions. Compared with the traditional tank reactor process, less raw material consumption, higher product yield, less reaction time, higher operation safety ensured by more the environmentally friendly procedure, and process continuity are achieved in the continuous-flow system.

scholarly journals Synthesis of bifunctional nanocatalyst from waste palm kernel shell and its application for biodiesel production

RSC Advances ◽  
2020 ◽  
Vol 10 (45) ◽  
pp. 27183-27193
Author(s):  
Rose Fadzilah Abdullah ◽  
Umer Rashid ◽  
Yun Hin Taufiq-Yap ◽  
Mohd Lokman Ibrahim ◽  
Chawalit Ngamcharussrivichai ◽  
...  
Keyword(s):  
Palm Kernel ◽  
Biodiesel Production ◽  
Palm Kernel Shell ◽  
Mild Conditions ◽  
One Step

The potential of bifunctional nanocatalysts obtained from waste palm kernel shell (PKS) was investigated for one-step transesterification–esterification under mild conditions.

Mechanism of carbon-carbon bond formation in the reaction of 1,2-disubstituted alkenes with a cationic bridging methylidyne iron complex

1984 ◽  
Vol 106 (12) ◽  
pp. 3680-3681 ◽  
Author(s):  
Charles P. Casey ◽  
Mark W. Meszaros ◽  
Seth R. Marder ◽  
Paul J. Fagan
Keyword(s):  
Bond Formation ◽  
Iron Complex ◽  
Carbon Bond ◽  
Carbon Carbon Bond
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