scholarly journals Electrocardiographic Associations Seen with Obstructive Sleep Apnea

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Shyam Shankar ◽  
Sushilkumar Satish Gupta ◽  
Geurys Rojas-Marte ◽  
Selma Demir ◽  
Abhinav Saxena ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Final Analysis ◽  
Cost Effective ◽  
Respiratory Disorder ◽  
Continuous Variables ◽  
Chi Square ◽  
Multivariate Tests ◽  
S Waves ◽  
Obstructive Sleep

Background. Obstructive sleep apnea (OSA) is a chronic respiratory disorder associated with repeated nocturnal partial or complete collapse that is often underdiagnosed and associated with multiple comorbidities. The association between specific features on an electrocardiogram and OSA has not been well studied. This retrospective study attempts to bridge this gap in knowledge.Methods. A total of 265 patients’ medical records were reviewed retrospectively. Specific features of their electrocardiograms and their association with the severity of OSA were studied from April 2014 to May 2016. 215 patients were included in the final analysis. Tests of group difference between OSA patients and controls were done using student’s t-tests for continuous variables and using chi-square tests for categorical outcomes. Multivariate tests of differences between OSA and control patients were done using logistic regression to control for possible confounding factors.Results. A total of 215 patients with diagnosed OSA and 41 controls in whom OSA was ruled out using polysomnography were compared. Males were more likely to present with OSA than females (93 % versus 76 %; p < 0.001). OSA patients were also significantly older: 52.18 ± 14.04 versus 44.55 ± 14.64; p = 0.002. Deep S waves in V5-6 (p=0.014) and RS pattern with Deep S waves in leads I and AVF (p=0.017) were both significantly associated with OSA based on univariate comparisons. These findings lost significance in the multivariate analysis.Conclusion. The idea of using an electrocardiogram in aiding in the assessment of OSA is attractive and feasible, as it is a safe, noninvasive, and cost-effective method. Our results can be used for early risk stratification in patients with OSA.

435 Single Session CBT to Improve PAP Initiation and Adherence among Veterans with OSA

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A172-A172
Author(s):  
Todd Bishop ◽  
Patrick Walsh ◽  
Tracy Stecker ◽  
Katrina Speed ◽  
Lisham Ashrafioun ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Comparison Group ◽  
Behavioral Therapy ◽  
Subsequent Treatment ◽  
Single Session ◽  
Post Intervention ◽  
Chi Square ◽  
Treatment As Usual ◽  
Obstructive Sleep

Abstract Introduction Obstructive sleep apnea (OSA) is a condition that is prevalent, pernicious, and linked to the development and exacerbation of several disease processes. Positive airway pressure (PAP) is a highly efficacious intervention; however, initiation and adherence rates are poor. This represents a critical gap in care and a missed opportunity to reduce morbidity and mortality associated with OSA. The present study piloted a single session of cognitive behavioral therapy for treatment seeking (CBT-TS) among veterans diagnosed with obstructive sleep apnea and newly prescribed PAP. Methods Participants were asked to complete assessments at baseline and at two- and four-weeks post-intervention. A sample of 40 Veterans were enrolled in the study and completed a baseline interview, 27 completed CBT-TS. A matched comparison group of 64 veterans who did not receive the intervention was constructed using electronic medical record and PAP adherence data. Mann Whitney U and Chi Square tests were used to examine group differences in initiation and adherence. Results Participants who completed the CBT-TS session were more likely to initiate PAP (at least 3 consecutive nights of use) as compared to those receiving treatment as usual (TAU) [(CBT-TS; 96.3%; 26/27) versus (TAU; 64.1%; 41/64); X2(1, N = 91) = 10.16, p = .001]. Participants in the CBT-TS group also used their PAP devices for a greater number of nights over the first month than the comparison group [(CBT-TS; M = 21.7 (SD = 8.9), Mdn = 26.0) versus (TAU; M = 14.4 (SD = 12.6), Mdn = 15.5); U = 555.0, p = .007] and were more likely to use the device in an adherent manner (i.e., ≥4 hours use in an evening); [(CBT-TS; M = 15.1 (SD = 11.2); Mdn = 15.0) versus (TAU; M = 10.3 (SD = 11.2), Mdn = 6.5); U =630.0, p = .038]. Conclusion These preliminary data suggest that CBT-TS may have utility in increasing initiation of PAP and subsequent treatment adherence among Veterans diagnosed with OSA and newly prescribed PAP. Support (if any) This work was supported by the VA Center of Excellence for Suicide Prevention in the Finger Lakes Healthcare System.

Rapid Maxillary Expansion in Obstructive Sleep Apnea in Young Patients: Cardio-Respiratory Monitoring

2017 ◽  
Vol 41 (4) ◽  
pp. 312-316 ◽  
Author(s):  
Alfio Buccheri ◽  
Fabio Chinè ◽  
Giovanni Fratto ◽  
Licia Manzon
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Young Patients ◽  
Rapid Maxillary Expansion ◽  
Respiratory Monitoring ◽  
Respiratory Disorder ◽  
Maxillary Expansion ◽  
Mean Values ◽  
Obstructive Sleep ◽  
The Mean

Objective(s): Obstructive sleep apnea syndrome (OSAS) is a respiratory disorder which affects from 1 to 3 % of people during development. OSAS treatment may be pharmacological, surgical or based on application of intraoral devices to increase nasal respiratory spaces. The purpose of this study was to determine the efficacy of the Rapid Maxillary Expander in OSAS young patients by measuring cardio-respiratory monitoring parameters (AHI, the average value of complete and incomplete obstructed respiration per hour of sleep, and SAO2, the percentage of oxygen saturation). Study design: The study was conducted on 11 OSAS young subjects (mean age 6.9±1.04 years), all treated with rapid maxillary expansion (RME). Cardio-respiratory monitoring (8-channel Polymesam) was performed at the beginning (diagnostic, T0) and after 12 months of treatment. Results: The mean values of cardio-respiratory parameters at TO were: AHI=6.09±3.47; SAO2=93.09%±1.60. After 12 months of treatment, the mean values of the same polysomnographic parameters were: AHI=2.36 ± 2.24;SAO2=96.81% ±1.60. These changes were associated with an improvement in clinical symptoms, such as reduction of snoring and sleep apnea. Conclusion(s): This study confirms the therapeutic efficacy of RME in OSAS young patients. This orthopedic-orthodontic treatment may represent a good option in young patients affected by this syndrome.

scholarly journals Obstructive Sleep Apnea Syndrome (OSAS) Decrease Concentration Levels in Young Adults

2020 ◽  
Vol 1 (2) ◽  
pp. 17-20
Author(s):  
Fidela Hanan Zivana
Keyword(s):  
Obstructive Sleep Apnea ◽  
Young Adults ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Concentration Level ◽  
Sleep Apnea Syndrome ◽  
Chi Square ◽  
Obstructive Sleep ◽  
Chi Square Test ◽  
Apnea Syndrome

Background: Obstructive Sleep Apnea Syndrome (OSAS) is sleeping-disorder that’s characterized by recurrent episodes of upper airway obstruction during sleep. Fourteen percent of world populations suffer from OSAS. OSA patients are 7,5 to 20 times more likely to have difficulties with concentration, learning new tasks, and execution of monotonous tasks.Objective: The primary objective of this study was to investigate the relationship between Obstructive Sleep Apnea Syndrome (OSAS) and concentration level in young adults.Methods: This is an analytic observational study with cross-sectional design. Sampling was carried out with total sampling. Samples that qualified the inclusion and exclusion criteria were assessed by OSAS using the Epworth Sleepiness Scale (ESS)  questionnaire and Digit Symbol Substitution Test was used to assess the concentration level. The data were analyzed, using the chi-square test and the prevalence (PR) test.Results: The Chi-square test showed that there was a significant relationship between OSAS and concentration level (p=0.033). The Prevalence Ratio test found that OSAS decreased concentration level by 1,55 compared to not OSAS.Conclusion:  There was a significant relationship between OSAS and concentration level in young adults. OSAS patients are 1,55 more likely to have a decrease concentration level when compared with healthy individuals.

Polysomnography in Pediatric Otolaryngology: If Not Obstructive Sleep Apnea, What Is It?

2017 ◽  
Vol 157 (6) ◽  
pp. 1053-1059 ◽  
Author(s):  
Christine H. Heubi ◽  
Jareen Meinzen-Derr ◽  
Sally R. Shott ◽  
David F. Smith ◽  
and Stacey L. Ishman
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sleep Disturbances ◽  
Case Series ◽  
Central Sleep Apnea ◽  
Categorical Variables ◽  
Periodic Limb Movements ◽  
Continuous Variables ◽  
Retrospective Case ◽  
Obstructive Sleep

Objective To determine common polysomnographic (PSG) diagnoses for children referred by otolaryngologists. Study Design Retrospective case series with chart review. Setting Single tertiary pediatric hospital (2010-2015). Subjects and Methods Review of the medical records of 1258 patients undergoing PSG by otolaryngology referral. Patients who underwent previous otolaryngologic surgery were excluded. Data distributions were evaluated using means with standard deviations for continuous variables and frequencies with percentages for categorical variables. Results A total of 1258 patients were included; 55.9% were male, 64.5% were Caucasian, 16.6% had Down syndrome, and 48% had public insurance. The median age at the time of PSG was 5.2 years (range = 0.2-18.94). Indications for PSG were sleep-disordered breathing (SDB; 69.4%), restless sleep (12.7%), airway anomalies (7.5%), and laryngomalacia (7.2%). SDB was seen in 73.4%, obstructive sleep apnea (OSA) in 53.2%, OSA + central sleep apnea (CSA) in 4.5%, CSA in 0.9%, and non-OSA snoring in 15%. Other diagnoses included periodic limb movements of sleep (PLMS; 7.4%), hypoventilation (6.8%), and nonapneic hypoxemia (2.6%). SDB was more common in younger children and seen in 91.4% of children <12 months and in 69.2% of children ≥24 months, while non-OSA snoring was more common with increasing age (3.7% in children <12 months, 17.7% of children ≥24 months). PLMS were seen in 8.9% of children ≥24 months and in no children <12 months. Conclusion While OSA and snoring were the most common diagnoses reported, PLMS, alveolar hypoventilation, and CSA occurred in 7.4%, 6.8%, and 5.4%, respectively. These findings indicate that additional diagnoses other than OSA should be considered for children seen in an otolaryngology clinic setting who undergo PSG for sleep disturbances.

scholarly journals Hubungan saturasi oksigen dengan risiko terjadinya obstructive sleep apnea pada pria usia 30 - 60 tahun

2020 ◽  
Vol 3 (2) ◽  
pp. 58-62
Author(s):  
Dhia Maulidya Mirwan ◽  
Eveline Margo
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Pulse Oximetry ◽  
Random Sampling ◽  
Chi Square ◽  
Cross Sectional ◽  
Obstructive Sleep

LATAR BELAKANGObstructive sleep apnea (OSA) merupakan kondisi umum pada saat tidur ditandai dengan mendengkur. Di Indonesia, data prevalensi OSA masih sangat sedikit, namun pada penelitian di Jakarta tahun 2013 didapatkan 70% pada laki-laki dengan rentang usia 35-73 tahun menderita OSA. Kejadian OSA dapat mengganggu sistem pernapasan serta fungsi kognitif seseorang. Hal ini ditandai dengan hipoksia yang dapat menimbulkan fase arousal pada risiko OSA. Namun, pada beberapa penelitian ditemukan tidak terdapatnya hubungan kadar saturasi oksigen pada penderita OSA sehingga membuat peneliti hendak menilai kembali. Tujuan penelitian ini untuk mengetahui hubungan saturasi oksigen dengan risiko terjadinya OSA pada pria usia 30-60 tahun. METODEPenelitian ini menggunakan studi observasional analitik dengan desain studi potong lintang (cross-sectional) yang dilakukan pada bulan April hingga Juni 2019. Penentuan sampel menggunakan teknik random sampling, pada 64 orang pria usia 30-60 tahun. Data dikumpulkan dengan cara wawancara menggunakan kuesioner Berlin untuk mengetahui ada tidaknya OSA dan dilakukan pengukuran saturasi oksigen menggunakan pulse oximetry. Analisis hipotesis dilakukan dengan uji Chi-square dengan tingkat kemaknaan yang digunakan p < 0.05. HASILDidapatkan responden 64 orang dengan 42 orang (65.6%) memiliki risiko tinggi OSA, dan 22 orang (34.4%) lainnya memiliki risiko rendah OSA, sedangkan pada uji Chi-square untuk melihat hubungan kadar saturasi oksigen dengan resiko terjadinya OSA didapatkan p=1.000. KESIMPULANPenelitian ini menunjukan tidak ada hubungan bermakna antara kadar saturasi oksigen dengan risiko terjadinya OSA.

scholarly journals Hubungan Berat Badan dengan Kualitas Tidur pada Mahasiswa Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Kristen Krida Wacana Angkatan 2016

2020 ◽  
Vol 26 (2) ◽  
Author(s):  
Mohamad Naim Bin Hasan ◽  
William William ◽  
Flora Rumiati
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sleep Quality ◽  
Quality Index ◽  
Pittsburgh Sleep Quality Index ◽  
Chi Square ◽  
Cross Sectional ◽  
Purposive Sampling ◽  
Obstructive Sleep

Kelebihan berat badan merupakan faktor independen yang berkontribusi terhadap kualitas tidur yang buruk. Sleep apnea merupakan timbulnya episode abnormal pada frekuensi napas yang berhubungan dengan penyempitan saluran napas atas pada saat tidur. Sleep apnea dapat berupa henti napas (apnea) atau menurunnya ventilasi yang akan menyebabkan gangguan bernapas saat tidur. Semakin besar nilai Indeks Massa Tubuh (IMT) atau bertambahnya berat badan, kemungkinan untuk mengalami Obstructive Sleep Apnea (OSA) semakin tinggi. Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara IMT dengan kualitas tidur pada mahasiswa kedokteran angkatan 2016 FKIK Ukrida. Jenis penelitian yang digunakan adalah penelitian cross sectional dengan menggunakan studi komparatif, yaitu untuk mengetahui hubungan antara IMT dengan kualitas tidur pada mahasiswa golongan berat badan lebih dan berat badan normal. Teknik sampling yang digunakan dalam penelitian ini adalah purposive sampling. Sebanyak  88 responden berpartisipasi dalam penelitian ini, terdiri dari 44 mahasiswa yang mempunyai berat badan normal dan 44 mahasiswa yang mempunyai berat badan lebih. Responden mengisi kuesioner Pittsburgh Sleep Quality Index (PSQI).   Hasil penelitian menunjukkan sebanyak 64 responden (72,7%) mempunyai kualitas tidur buruk, dan 24 responden (27,3%) memiliki kualitas tidur yang baik, serta durasi tidur terbanyak adalah < 6 jam.  Berdasarkan uji Chi-Square, disimpulkan adanya hubungan antara berat badan dengan kualitas tidur (p = 0,000, p < 0,05) pada mahasiswa Fakultas Kedokteran angkatan 2016 FKIK Ukrida.

High-Resolution Pulse Oximetry (HRPO): A Cost-Effective Tool in Screening for Obstructive Sleep Apnea (OSA) in Acute Stroke and Predicting Outcome

2018 ◽  
Vol 27 (11) ◽  
pp. 2986-2992 ◽  
Author(s):  
Sridhara Sastry Yaddanapudi ◽  
Maria Carissa Pineda ◽  
David W. Boorman ◽  
Richard E. Bryne ◽  
Krista Lim Hing ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
High Resolution ◽  
Pulse Oximetry ◽  
Acute Stroke ◽  
Cost Effective ◽  
Obstructive Sleep ◽  
Predicting Outcome

scholarly journals Obstructive sleep apnea is not an independent determinant of testosterone in men

2020 ◽  
Vol 183 (1) ◽  
pp. 31-39 ◽  
Author(s):  
Brigette Marie Clarke ◽  
Andrew D Vincent ◽  
Sean Martin ◽  
Robert Adams ◽  
Sarah Appleton ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Final Analysis ◽  
Serum Testosterone ◽  
Sex Hormone Binding Globulin ◽  
Study Cohort ◽  
Linear Regression Models ◽  
Testosterone Concentration ◽  
Obstructive Sleep ◽  
Prospective Longitudinal

Objective Obstructive sleep apnea (OSA) is generally considered to lower serum testosterone concentration in men, although data supporting this as a direct effect are limited. The aim of this study was to determine the relationship between the presence and severity of OSA and testosterone in a community-based cohort of men aged over 40 years. Design and methods Anthropometry, polysomnography and biomedical information were collected from enrolled, consenting men from the prospective, longitudinal MAILES study cohort. Fasting morning blood samples (n = 1869) were drawn between 2010 and 2012 for measurement of testosterone using liquid chromatography mass spectrometry. Home polysomnography was completed in 861 men between 2010 and 2012. The final analysis sample consisted of 623 men aged 41–86 years. The effect of OSA on testosterone were analyzed using linear regression models controlling for potential confounders (age, BMI and sex hormone binding globulin (SHBG)). Results The mean (s.d.) cohort characteristics were: age 59.0 (10.2) years, testosterone 16.8 (5.3) nmol/L, SHBG 32.9 (13.1) nmol/L, BMI 28.6 (4.2) kg/m2 and apnoea hypopnoea index (AHI) 14.9 (13.7). OSA was present in 51.5%. There was an inverse relationship between AHI and testosterone (P = 0.01), which was lost after covariate adjustment. Conclusions These data suggest that obesity, rather than OSA per se, determine testosterone concentration. This accords with the graded effect of weight loss, but limited effect of continuous positive airway pressure to increase testosterone, and highlights the importance of managing obesity in men with low testosterone concentration, particularly in the context of OSA.

scholarly journals 1094 Depression Is Not Associated With The Presence Of Or The Severity Of Obstructive Sleep Apnea: Retrospective Study Of 841 Polysomnography Subjects

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A416-A416
Author(s):  
K Im ◽  
L Kim ◽  
R Immen
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Rating Scale ◽  
Numerical Rating Scale ◽  
Significant Proportion ◽  
Chi Square ◽  
Relative Paucity ◽  
Obstructive Sleep ◽  
Significant Difference ◽  
Chi Square Analysis

Abstract Introduction Both depression and obstructive sleep apnea (OSA) are very common medical conditions. Studies showed a co-occurrence of depression and OSA with a higher prevalence of one if the other is present. However, there is relative paucity of studies assessing the rate of depression based on the OSA severity. Methods Retrospective analysis of data collected from patients undergoing polysomnography (PSG) at an academic sleep disorders center was performed. A total of 841 subjects were included and stratified into four groups using AHI. A Chi-square analysis was applied to assess the association of varying levels of AHI and the presence of depression. Results Although a significant proportion of patients with AHI greater than 5 endorsed depression (60/165 in group with AHI 15 or greater and 115/278 in group with AHI between 5 and 15), this finding was also replicated in patients with AHI less than 5 (86/202 in AHI between 1 and 5 and 88/196 in those with AHI less than 1). As there was significant difference in rate of depression among women (54.1%) and men (26.1%) (p &lt;0.0001), Chi-square analysis was performed for the rate of depression based on the level of AHI, adjusted for gender. In women the rate of depression from the most severe AHI to less severe AHI group were 0.48, 0.53, 0.60, and 0.53 respectively and in men it was 0.30, 0.27, 0.20, and 0.27 respectively, with no statistical difference between any groups. Conclusion Among patients who seek PSG assessment, depression appears to be more prevalent than the general public. Rate of depression is much higher among women than men in this group. However, the presence of OSA or severity of OSA does not have any correlation with the rate of depression in both women and men. These findings might be suggestive of the complexity of the association between depression and OSA. One limitation of this study is the dichotomous nature of depression (presence or absence of). The finding from this study warrants a future study utilizing a numerical rating scale of depression for severity measure to correlate it with the severity of OSA. Support NA.

scholarly journals Caregiver support and positive airway pressure therapy adherence among adolescents with obstructive sleep apnea

2019 ◽  
Vol 25 (8) ◽  
pp. 491-497 ◽  
Author(s):  
Arpita Parmar ◽  
Sandra Messiha ◽  
Adele Baker ◽  
Allison Zweerink ◽  
Alene Toulany ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Retrospective Study ◽  
Sleep Apnea ◽  
Health Outcomes ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Continuous Variables ◽  
Pressure Therapy ◽  
Caregiver Support ◽  
Obstructive Sleep

Abstract Introduction Positive airway therapy (PAP) adherence rates are suboptimal among adolescents with obstructive sleep apnea (OSA) and strategies to increase PAP adherence is a clinical priority. This study evaluates if caregiver support is associated with PAP adherence rates among adolescents with OSA. Methods We conducted a retrospective study and evaluated PAP adherence rates among adolescents with OSA from 2012 to 2017. Adherence was measured as continuous variables: average PAP usage (minutes per night) and average PAP usage &gt;4 hours/night (% of all nights). We evaluated if adolescents with OSA who were receiving practical caregiver support with PAP had higher adherence than adolescents with OSA without caregiver support. Results One hundred and seven adolescents with OSA (mean age=14.1±2.5 years, 64.5% male, mean BMI percentile=89.0±21.8) seen between January 2012 and August 2017 at our institution were included. In this study, 60.7% (n=65) of adolescents with OSA were receiving practical caregiver support with PAP therapy. Adolescents with OSA receiving practical caregiver support with PAP used therapy for a significantly greater duration each night compared to adolescents who were not receiving practical caregiver support (298.5±206.7 versus 211.9±187.2 minutes; P=0.02). Greater time since the initial PAP prescription was independently associated with PAP adherence. Conclusion Focusing on PAP adherence early may help adolescents with OSA incorporate therapy into their nightly routine, which may improve adherence and lead to improved health outcomes in adolescents with OSA. Practical caregiver support may be an essential component of ensuring optimal PAP adherence among adolescents with OSA.

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