scholarly journals The Association between Preoperative Dry Eye Symptoms and Postoperative Discomfort in Patients Underwent Photorefractive Keratectomy

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Gilad Rabina ◽  
Ingibjorg Iris Boguslavsky ◽  
Michael Mimouni ◽  
Igor Kaiserman
Keyword(s):  
Postoperative Pain ◽  
Dry Eye ◽  
Subjective Evaluation ◽  
Case Series ◽  
Photorefractive Keratectomy ◽  
Ocular Surface Disease Index ◽  
Retrospective Case ◽  
Significant Difference ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

Purpose. To investigate the association between preoperative dry eye symptoms on postoperative pain and discomfort after photorefractive keratectomy (PRK). Methods. A retrospective case series of 151 consecutive patients, who underwent myopic PRK in both eyes between 5/2016 and 5/2017. Patients with positive dry eye disease (DED) signs on clinical examination or with known DED were excluded. Patients underwent a subjective evaluation for dry eye symptoms using ocular surface disease index (OSDI) and modified standard patient evaluation of eye dryness (SPEED) questionnaires. One day postoperatively, the patients were evaluated again by a questionnaire of pain, discomfort, photophobia, foreign body sensation, satisfaction with vision, and frequency of usage of anesthetic drops. Results. Fifty-two patients had any preoperative dry eye symptoms (OSDI score > 0) compared to 99 nonsymptomatic patients (OSDI score of 0). Postoperatively, the symptomatic dry eye patients suffered significantly more pain than the nondry eye patients (p=0.02). Thirteen patients had a cumulated modified SPEED score >4 (moderate to severe) in comparison to 138 patients with score of 0–4 (non to mild). Patients with moderate to severe preoperative symptoms suffered more pain (p=0.006), photophobia (p=0.005), and epiphora (p=0.03). No statistically significant difference was seen in postoperative subjective visual quality (p=0.82) between the two groups. Conclusion. Preoperative dry eye symptoms may be associated with postoperative pain, epiphora, and photophobia and thus influence negatively on patient satisfaction with this procedure.

scholarly journals Leptin’s concentration in tears and dry eye: a clinical observational study

2021 ◽  
Vol 14 (1) ◽  
pp. 83-88
Author(s):  
Ran Hao ◽  
◽  
Xue-Min Li ◽  
Keyword(s):  
Dry Eye ◽  
Linear Regression Analysis ◽  
Multivariate Linear Regression Analysis ◽  
Ocular Surface Disease Index ◽  
Fluorescein Staining ◽  
Significant Difference ◽  
Eye Symptoms ◽  
Tear Meniscus Height ◽  
Symptoms And Signs ◽  
Dry Eye Symptoms

AIM: To investigate the concentration of leptin in tears and its correlation with dry eye symptoms and signs. METHODS: The study enrolled individuals (n=39) responding to an advertising or dry eye patients (n=58) from the Ophthalmology Department. Tear samples were collected for leptin concentration measuring. Ocular Surface Disease Index (OSDI), tear meniscus height (TMH), tear break up time (TBUT), cornea fluorescein staining, Schirmer test (ST) and impression cytology (IC) were assessed. Leptin concentration in tears of dry eye patients and healthy controls, and its correlation with clinical features of dry eye disease (DED) were analyzed. RESULTS: Age, body mass index (BMI), OSDI scores and cornea fluorescein staining scores showed a negative correlation with leptin concentration in tears (r=-0.340, P=0.001; r=-0.332, P=0.001; r=-0.258, P=0.011; r=-0.424, P<0.001, respectively). ST showed positive correlation with leptin concentration in tears (r=0.206, P=0.045). No significant difference was observed in leptin concentration between dry eye patients and controls (P=0.682). Multivariate linear regression analysis revealed that dry eye, OSDI, corneal fluorescein staining scores and ST correlated with leptin concentration in tears. CONCLUSION: This is the first study measuring leptin concentration in tears. The correlation between leptin concentration and DED symptoms and signs reveal that leptin level correlated with the dry eye, potentially contributing to repair of ocular damage and dry eye improvement.

scholarly journals Comparable effects on tear film parameters after femtosecond laser-assisted and conventional cataract surgery

2020 ◽  
Vol 40 (11) ◽  
pp. 3097-3104 ◽  
Author(s):  
Marc Schargus ◽  
Svetlana Ivanova ◽  
Gesa Stute ◽  
H. Burkhard Dick ◽  
Stephanie C. Joachim
Keyword(s):  
Femtosecond Laser ◽  
Cataract Surgery ◽  
Dry Eye ◽  
Surgical Techniques ◽  
Tear Film ◽  
Schirmer Test ◽  
Fluorescein Staining ◽  
Significant Difference ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

Abstract Purpose Dry eye symptoms after conventional cataract surgery are a very common problem. Until now, only few data are available on objective tear film parameters in regard to femtosecond laser-assisted cataract surgery (LCS). Aim of this study was therefore to analyze and compare tear film parameter changes between LCS and conventional cataract surgery. Methods A consecutive group of 34 patients, scheduled for cataract surgery, were randomly selected for either LCS or conventional cataract surgery (17 patients/group). Tear film assessments including tear film osmolarity, Schirmer test, MMP-9 analysis via quantitative ELISA, corneal sensitivity, corneal fluorescein staining, and conjunctival fluorescein staining were sequentially evaluated pre- as well as 1 and 3 months postoperatively. Results Both groups showed no significant difference in baseline characteristics. All surgeries were performed without any complications. After 1 and 3 months, there was no statistically significant difference in regard to tear film osmolarity (1 month: p = 0.81, 3 months: p = 1.0), Schirmer test (1 month: p = 0.35, 3 month: p = 0.08), and MMP-9 concentration (1 month: p = 0.36, 3 month: p = 0.28) between the two groups. Conclusions Neither LCS nor conventional cataract surgery affected objective tear film parameters significantly during our 3-month postoperative observation period. Hence, both surgical techniques can be equally used to treat patients without prior dry eye symptoms.

Botulinum A Toxin Injection as a Treatment for Blepharospasm

2020 ◽  
pp. 275-278
Author(s):  
Alan D. Penman ◽  
Kimberly W. Crowder ◽  
William M. Watkins
Keyword(s):  
Cerebrovascular Disease ◽  
Dry Eye ◽  
Case Series ◽  
Orbicularis Oculi ◽  
Eyelid Surgery ◽  
Botulinum A Toxin ◽  
Duration Of Effect ◽  
Eye Symptoms ◽  
Dose Dependent ◽  
Dry Eye Symptoms

In this chapter a case series is described of the use of botulinum A toxin for the treatment of blepharospasm in thirty-nine patients with blepharospasm due to various causes—essential, Meige’s syndrome, hand apraxia, cerebrovascular disease, and parkinsonism. A reduction of abnormal movement occurred in all patients, lasting up to 170 days. Both the amount and the duration of effect were dose dependent. Tearing, dry-eye symptoms, or transient ptosis occurred in 20% of injections, especially in patients who had had previous eyelid surgery. Botulinum A toxin injection into the orbicularis oculi muscle was found to be a safe, simple, and symptomatically helpful treatment for blepharospasm that can be repeated at intervals as required.

scholarly journals Effect of dry eye diseases on the level of Protein and Lipids in Tears of Postmenopausal Women.

2021 ◽  
Vol 46 (1) ◽  
Author(s):  
A.O. Shuaibu ◽  
G. A. Akinlabi
Keyword(s):  
Postmenopausal Women ◽  
Dry Eye ◽  
Total Protein ◽  
Clinical Signs ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Ocular Surface Disease Index ◽  
Significant Difference ◽  
Eye Symptoms ◽  
Breakup Time

The study is aimed at investigating the effect of dry eye disease on the level of protein and lipids in tears of postmenopausal women. The study was carried out on 33 postmenopausal women with dry eye symptoms and 22 postmenopausal women that were asymptomatic. The ocular surface disease index (OSDI) questionnaire classified participants as being symptomatic or asymptomatic of dry eye. Tear stability and tear volume were assessed with Fluorescein Tear Break up Time (FBUT) and Schirmer’s test respectively. Tears were analysed for protein (total protein, albumin, and globulin) and lipid (cholesterol and triglycerides). The mean total protein for Dry Eye (DE) was higher than that for Non-dry eye (NDE). Albumin and globulin were also higher for the DE group when compared to the NDE group. These were however, not statistically significant (p > 0.05). There was also no significant difference in triglycerides and cholesterol between DE and NDE. There was no significant correlation between clinical signs (tear volume and tear breakup time) and total protein, albumin, globulin cholesterol and triglycerides in the NDE and DE eye groups. The study shows that proteins and lipids do not change in postmenopausal women irrespective of the presences of dry eye disease.

scholarly journals Prevalence and Risk Factors of Severe Dry Eye in Bangladesh-Based Factory Garment Workers

Diagnostics ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 634 ◽  
Author(s):  
Mamunur AKM Rashid ◽  
Calesta Hui Yi Teo ◽  
Sumaiya Mamun ◽  
Hon Shing Ong ◽  
Louis Tong
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Age Groups ◽  
Meibomian Gland ◽  
Ocular Surface Disease Index ◽  
Cross Sectional ◽  
Garment Workers ◽  
Severity Grading ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

This study sought to evaluate the prevalence of dry eye and meibomian gland dysfunction (MGD) and the associated factors of severe dry eye symptoms (SDES) among garments worker of Gazipur, Bangladesh. We prospectively collected cross-sectional data for 1050 garments workers of a factory (70% response). All participants had an evaluation of the Ocular Surface Disease Index (OSDI), and a detailed ophthalmic examination including tear breakup time (TBUT), ocular surface fluorescein staining, and Schirmer’s I test. MGD grading was based on the viscosity/color and ease of manual expression of meibum. Mean age of participants was 35.5 ± 12.1 years; 53.8% were women. The prevalence of dry eye (OSDI > 12) was 64.2% (95% CI 61.2–67.1%). OSDI was not significantly different between sex or age-groups but associated with increasing MGD grade (p < 0.001), reduced TBUT (<5 s) [p < 0.001], and reduced Schirmer’s test (<5 mm) [p < 0.001]. Thirty-five percent had SDES (OSDI > 32). Using univariate logistic regressions, SDES was associated with older age (Odds Ratio (OR) 1.01, 95% Confidence Interval [1.005–1.03] per year increase) and male sex (OR 1.76, 95% CI: 1.36–2.27). When adjusted for age and sex, SDES were strongly associated with increase in MGD severity grading (OR 188, 95% CI: 91–390). However, in multivariate regression, TBUT, but not MGD severity, became the only significant determinant of SDES (OR 13.0, 95% CI: 6.3–27.0, for every 1 s decrease in TBUT). MGD is common in garments workers, contributing to dry eye symptoms in addition to other tear parameters. Reduced tear stability is associated with SDES.

scholarly journals Prevalence and pattern of dry eye symptoms among “okada” riders in Southwest Nigeria using the ocular surface disease index: A cross sectional study

2021 ◽  
Vol 18 (2) ◽  
pp. 81
Author(s):  
AdetunjiOlusesan Adenekan ◽  
OlubankeTheodora Ilo ◽  
AdegboyegaSunday Alabi ◽  
OlufisayoTemitayo Aribaba ◽  
FolasadeBolanle Akinsola
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Cross Sectional Study ◽  
Disease Index ◽  
Sectional Study ◽  
Ocular Surface Disease Index ◽  
Cross Sectional ◽  
Southwest Nigeria ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

scholarly journals Investigation of Dry Eye Symptoms in Lecturers by Ocular Surface Disease Index

2019 ◽  
Vol 49 (3) ◽  
pp. 142-148 ◽  
Author(s):  
Sümbüle Köksoy Vayısoğlu ◽  
Emine Öncü ◽  
Özer Dursun ◽  
Erdem Dinç
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Disease Index ◽  
Ocular Surface Disease ◽  
Ocular Surface Disease Index ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

scholarly journals Anatomical and Visual Outcomes after LASIK Performed in Myopic Eyes with the WaveLight® Refractive Suite (Alcon® Laboratories Inc., USA)

2020 ◽  
Vol 2020 ◽  
pp. 1-18
Author(s):  
Imene Salah-Mabed ◽  
Sarah Moran ◽  
Emmanuelle Perez ◽  
Guillaume Debellemanière ◽  
Damien Gatinel
Keyword(s):  
Contrast Sensitivity ◽  
Dry Eye ◽  
High Myopia ◽  
Spherical Aberration ◽  
Case Series ◽  
Corneal Aberrations ◽  
Quality Of Vision ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

Purpose. To evaluate changes in corneal anatomy and quality of vision following LASIK refractive surgery for mild to high myopia using the WaveLight® Refractive Suite (Alcon® Laboratories Inc., USA). Setting. Rothschild Foundation, Paris, France. Design. Prospective interventional case series. Methods. We examined 60 myopic eyes (average SE −4.5 D, from −9.3 to −0.75 D) of 30 patients from 21.3 to 38.7 years old. Pachymetry, keratometry, Q factor, corneal aberrations, visual acuity (VA), contrast sensitivity, dry eye assessment, and quality of vision were measured preoperatively, one day (D1), and 1, 3, and 6 months postoperatively. Results. 6 months postoperatively, keratometry became flatter, and the Q factor became more oblate (from −0.18 ± 0.08 to +0.19 ± 0.06). Pachymetry decreased by 117.9 ± 62.2 µm at D1 and increased by 37.87 ± 32.6 µm between D1 and M6. Refraction was emmetropic at D1 and remained stable thereafter. Six months after surgery, VA was slightly but nonsignificantly improved (<0.05 log MAR), whereas contrast sensitivity remained unchanged. Quality of vision was not affected by surgery and was more related to dry eye symptoms than to corneal HOAs (r2 = 0.49; p<0.001 vs. r2 = 0.03; p<0.001). Conclusions. LASIK surgery for moderate to high myopia, performed with the WaveLight® Refractive Suite, showed good postoperative outcomes, with demonstrated safety, predictability, efficiency, and stability. This is probably due to well-controlled spherical aberration and the use of large optical zones. Besides, we can assume that the patients’ quality of vision depends more on the postoperative dry eye disease generated by the laser than on the induced HOAs.

Sign in / Sign up

Export Citation Format

Share Document