scholarly journals Primary Stromal Breast Sarcoma with Concomitant Contralateral Carcinoma: A Rare Case from Syria

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Rawan Al khudari ◽  
Mohannad Homsi ◽  
Hasan Al zohaily ◽  
Maher S. Saifo

Bilateral breast cancers are rare cases encountered and are usually the same type in both sides. Only very few cases were reported to have different histological types of neoplasia involving sarcoma. Moreover, sarcomas rarely originate from the breast as a primary lesion whereas the common presentation is having angiosarcoma following radiotherapy. In this report, we present a rare case of a Syrian 43-year-old woman having two distinct primary lesions in the breasts: invasive ductal carcinoma and contralateral stromal sarcoma.

2016 ◽  
Vol 23 (1) ◽  
pp. 102-103
Author(s):  
Deniz Firat ◽  
Gokhan Ozturk ◽  
Eren Demirbas ◽  
Oguz Idiz ◽  
Arda Isik ◽  
...  

2018 ◽  
Vol 13 (3) ◽  
pp. 602-605 ◽  
Author(s):  
Gaurav Anand ◽  
Nabil Al-Khalisi ◽  
Dauod Arif ◽  
Soheila Hamidpour ◽  
Tiffany Lewis

Cureus ◽  
2018 ◽  
Author(s):  
Heather Katz ◽  
Hassaan Jafri ◽  
Rahoma Saad ◽  
Teresa Limjoco ◽  
Maria T Tirona

2009 ◽  
Vol 11 (3) ◽  
pp. 186-188 ◽  
Author(s):  
Sofia Broco ◽  
Nuno Bonito ◽  
Paula Jacinto ◽  
Gabriela Sousa ◽  
Helena Gervásio

2009 ◽  
Vol 2009 ◽  
pp. 1-8 ◽  
Author(s):  
Piotr Ziółkowski ◽  
Elżbieta Gamian ◽  
Beata Osiecka ◽  
Alexandre Zougman ◽  
Jacek R. Wiśniewski

Nuclear ubiquitous casein and cyclin-dependent kinases substrate (NUCKS) is 27 kDa chromosomal protein of unknown function. Its amino acid composition as well as structure of its DNA binding domain resembles that of high-mobility group A, HMGA proteins. HMGA proteins are associated with various malignancies. Since changes in expression of HMGA are considered as marker of tumor progression, it is possible that similar changes in expression of NUCKS could be useful tool in diagnosis and prognosis of breast cancer. For identification and analysis of NUCKS we used proteomic and histochemical methods. Analysis of patient-matched samples of normal and breast cancer by mass spectrometry revealed elevated levels of NUCKS in protein extracts from ductal breast cancers. We elicited specific antibodies against NUCKS and used them for immunohistochemistry in invasive ductal carcinoma of breast. We found high expression of NUCKS in 84.3% of cancer cells. We suggest that such overexpression of NUCKS can play significant role in breast cancer biology.


Breast Cancer ◽  
2010 ◽  
Vol 21 (2) ◽  
pp. 241-245 ◽  
Author(s):  
Shunsuke Onoe ◽  
Hitoshi Tsuda ◽  
Sadako Akashi-Tanaka ◽  
Takahiro Hasebe ◽  
Eriko Iwamoto ◽  
...  

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