scholarly journals Trimethoprim-Sulfamethoxazole-Induced Aseptic Meningitis: A Rare Presentation of Commonly Used Antibiotic

2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Salem Agabawi

Drug-induced aseptic meningitis is a rare medical condition with trimethoprim-sulfamethoxazole being one of the most common antimicrobial agents associated with it. Here, I report a case of a 56-year-old male who presented to a health care facility with shock and meningitis-like syndrome in two occasions, one year apart following an exposure to trimethoprim-sulfamethoxazole for treatment of skin/soft tissue infection. Investigations did not reveal an infectious etiology in the two presentations. The patient improved with supportive care and withdrawal of the offending agent. In the two admissions, the patient improved following stopping the offending drug in addition to supportive care. The diagnosis of trimethoprim-sulfamethoxazole-induced aseptic meningitis was the most likely explanation for this case. Trimethoprim-sulfamethoxazole-induced aseptic meningitis is rare although it is a life-threatening side effect of TMP/SMX; therefore, the clinicians should keep the diagnosis of drug-induced aseptic meningitis in the differential diagnosis of aseptic meningitis in the appropriate clinical setting as early withdrawal of the culprit drug and supportive measurements will lead to early recovery.

Author(s):  
Manish Munjal ◽  
Harsimran Bhatti ◽  
Japneet Kaur ◽  
Porshia Rishi ◽  
Shubam Munjal

<p class="abstract"><strong>Background:</strong> Benign paraoxysmal positional vertigo (BPPV) has been attributed to be one of the commonest causes of vertigo presenting to the clinician. However, this often remains undiagnosed and undertreated, epidemiology remaining an underexplored territory for this disorder.</p><p class="abstract"><strong>Methods:</strong> A study was carried out at outpatient clinic, Ear Nose Throat, Head and Neck services, Dayanand Medical College and Hospital, Punjab over a period of one year from 1<sup>st</sup> January to 31<sup>st</sup> December 2018. Based upon history, detailed otological examination, and Dix-Hallpike testing, 374 patients were evaluated for benign paroxysmal positional vertigo presenting with complaint of vertigo and dizziness in the vertigo clinic and were treated with Epley’s maneuver.  </p><p class="abstract"><strong>Results:</strong> Out of 374 patients evaluated, 79 patients were diagnosed as BPPV and underwent office management in the form of Epley’s maneuver.</p><p class="abstract"><strong>Conclusions:</strong> This study helps in effective team approach among practitioners and clinicians in the hospital for referring vertigo cases to ENT OPD for effective management of vertigo.</p><p class="abstract"> </p>


2016 ◽  
Vol 8 (1) ◽  
Author(s):  
Balaji Utla ◽  
Shailendra Kumar B. Hegde ◽  
Sri Ranga Prasad Saride ◽  
Ramanuja Chary Kandaala ◽  
Sridhar Upadhya ◽  
...  

This paper describes a cross-sectional analysis of data pertaining to accidents that occurred on the National Highway between Hyderabad and Vijaywada, over a period of one year. A fully equipped trauma ambulance was despatched to the site as soon as a call comes on 1033. The victim was attended to by well-trained paramedics in the ambulance and transported to the nearest health care facility. This service attended to 60% of the accidents in the service area. Incidence of fatalities was 5.63%. This service can be established at the national level to provide emergency ambulance care service to accident victims on National Highways.


2015 ◽  
Vol 16 (1) ◽  
pp. 43-50 ◽  
Author(s):  
Aleksandar Dagovic ◽  
Ana Zugic ◽  
Mihajlo B Jakovljevic

ABSTRACTHealthcare financing in Serbia has faced many challenges over the past few decades. One of the most severe challenges is a global macroeconomic recession whose far-reaching consequences deserve particular attention from policymakers in cases of the most demanding major prosperity diseases, such as cancer. The objective of the study was to assess the precise cost matrix of oncology medical care and its chronological evolution during the key years of the macroeconomic recessionary period during 2010-2013.A retrospective database of hospital discharge invoices was analysed, encompassing 37, 978 hospital admissions and 12, 505 patients during a four-year period. Insight into microeconomic patterns of consumption across groups of medical services was provided. A payer's perspective and one-year time horizon have been adopted.Total hospital direct medical costs of cancer diagnostics and treatment in the observed tertiary care facility decreased from €7, 411, 446 in 2010 to €5, 715, 884 in 2012 and then increased to an extraordinary €8, 536, 364 in 2013. The costs of oncology nursing care, imaging diagnostics and radiotherapy have increased considerably while those of pharmaceuticals and surgery have decreased radically - completely transforming the resource allocation landscape of public cancer care.The financial burden of cancer in Serbia is considerable and, unfortunately, expected to increase further in the coming years. Worldwide economic recession and consecutive domestic policy constraints of reimbursement limitations have heavily affected the affordability of cancer treatment for ordinary citizens. Promising signs of market recovery are clearly visible in 2013, which will likely improve both access and equity of medical care in Serbian oncology clinics.


2021 ◽  
Vol 7 (2) ◽  
pp. 143-147
Author(s):  
SK Malhotra ◽  
Baljit Kaur ◽  
Inderpal Kaur

Making the diagnosis of a drug-induced reaction requires familiarity with the clinical patterns as the current understanding of the disease processes is not enough to explain about apparently similar pathological mechanisms generating different clinical patterns. Therefore, it remains useful and relevant to overlay a pathological understanding with a clinical classification. This study concentrated on observing and documenting the clinical presentation of cutaneous adverse drug reactions (CADR) encountered in patients. The purpose of the study was to evaluate causality, severity and preventability of Dermatological ADRs.: To study morphological types of CADR and their incidence in Indian population Method: A prospective, observational study was carried out over a period of one year at Out Patient Department of Dermatology, Government Medical College, Amritsar with diagnosed CADRs. The suspected ADRs were evaluated for causality by Naranjo’s Probability scale and severity by Hartwig and Siegel scale.Total 54 patients were enrolled. The incidence of CADR was 0.09%. Most commonly manifested ADR was fixed drug eruption (FDE) i.e. 35.2%. Maximum incidence of dermatological ADRs were observed with antimicrobial agents (39%) followed by non-steroidal anti-inflammatory drugs (NSAIDS) (24%). Naranjo’s Probabilty scale showed most cases of probable (68.5%) ADRs were of moderate severity (90.7%). Awareness about CADR is essential for early detection, management of patients and drug safety. The healthcare system can promote the spontaneous reporting of dermatological ADR to Pharmacovigilance centers for ensuring safe drug usage and patient care.


2020 ◽  
pp. 105477382092457
Author(s):  
Catherine C. McDonald ◽  
Melissa R. Pfeiffer ◽  
Roni L. Robinson ◽  
Kristy B. Arbogast ◽  
Christina L. Master

Head injuries in childhood can result in concussion. Families of a child with a head injury often seek medical advice through telephone triage call systems. It is important to understand if patients follow telephone triage recommendations and what proportion of triage calls result in subsequent concussion diagnosis. We used a one-year retrospective cohort of triage calls screened with the Barton Schmitt Pediatric Head Injury Telephone Triage Protocol. The objectives were to estimate the proportion who followed up with urgent recommendations to see a provider and determine prevalence of diagnoses of concussion. Out of 2,454 calls with recommendations to be seen urgently, the estimated proportion of being seen in the medical home network or an outside health care facility was 84.1%. Estimated overall diagnoses of concussion among those who were seen was 39.5%. These data can be used to improve patient education and follow-up, as well as the utility of the telephone triage system.


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 380-384
Author(s):  
Priyanka Paul Madhu ◽  
Yojana Patil ◽  
Aishwarya Rajesh Shinde ◽  
Sangeeta Kumar ◽  
Pratik Phansopkar

disease in 2019, also called COVID-19, which has been widely spread worldwide had given rise to a pandemic situation. The public health emergency of international concern declared the agent as the (SARS-CoV-2) the severe acute respiratory syndrome and the World Health Organization had activated significant surveillance to prevent the spread of this infection across the world. Taking into the account about the rigorousness of COVID-19, and in the spark of the enormous dedication of several dental associations, it is essential to be enlightened with the recommendations to supervise dental patients and prevent any of education to the dental graduates due to institutional closure. One of the approaching expertise that combines technology, communications and health care facilities are to refine patient care, it’s at the cutting edge of the present technological switch in medicine and applied sciences. Dentistry has been improved by cloud technology which has refined and implemented various methods to upgrade electronic health record system, educational projects, social network and patient communication. Technology has immensely saved the world. Economically and has created an institutional task force to uplift the health care service during the COVID 19 pandemic crisis. Hence, the pandemic has struck an awakening of the practice of informatics in a health care facility which should be implemented and updated at the highest priority.


In the Netherlands geriatric rehabilitation is possible (among others) for patients who are selected by a geriatrician at the emergency department of a hospital. The aim of this study was to investigate the rehabilitation trajectory of patients who were selected for geriatric rehabilitation at the emergency department after a single contact with the geriatrician and to identify patient factors related to rehabilitation outcome. Successful rehabilitation was defined as discharge to home or a residential care facility after a maximum of 6 months. All patients who in 2016 were selected for geriatric rehabilitation were included. Data were collected retrospectively from electronic patient files. 74 patients were included (mean age 84.7 years). 84% were successfully discharged home or to a residential care facility within six months. The presentation with a fall and the absence of a partner at home was higher in the unsuccessful group. In the successful group more patients lived independent and without professional help prior to rehabilitation. Noteworthy is that the analysed patient group is a frail group, considering the high one-year mortality (21,6%) and overall functional decline despite geriatric rehabilitation.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Salma Khalid ◽  
Najibul Haq ◽  
Zia-ul-Ain Sabiha ◽  
Abdul Latif ◽  
Muhammad Amjad Khan ◽  
...  

Abstract Background Hospital waste management (HWM) practices are the core need to run a proper health care facility. This study encompasses the HWM practices in teaching hospitals of Peshawar, Pakistan and examine the enforcement of Pak HWM (2005) rules and risks through transmission of pathogens via blood fluids, air pollution during waste incineration and injuries occurring in conjunction with open burning and dumping. Methods A questionnaire based on World Health Organization (WHO) recommendations was used to survey the selected private and public teaching hospital (n = 16). Site visits and personnel observations were also included in the data. It was spatio-statistically analyzed using descriptive statistics, Krushkal-wallis and Fisher’s exact tests. Results The findings revealed that the lack of HWM practices in all surveyed hospitals (p > 0.05), besides statistical difference (p < 0.017) in waste generation/day. No proper segregation of waste from generation point to final disposal was practiced. However, the performance of private teaching hospitals (50%) was found better in terms of HWM personnel and practices. In surveyed hospitals, only nine hospitals (56.3%) were found with the incinerator facility while rest of the hospitals (43.7%) practiced open dumping. Moreover, operational parameters of the incinerators were not found satisfactory and located in densely populated areas and emitting hazardous gases. Conclusion Proper HWM practices are not being followed in the light of WHO guidelines. Hospital waste impose serious menace to healthcare workers and to nearby population. WHO issued documents for improving HWM practices but triggered no change in Pakistan. To improve the situation, insights in this context is need for enforcement of rules.


2021 ◽  
Vol 13 (1) ◽  
pp. 233-238
Author(s):  
Seyed Mohammad Mousavi Mirzaei ◽  
Zahra Ahmadi

Drug-induced aseptic meningitis (DIAM) is a rare complication of certain drugs, most commonly reported with ibuprofen use. The present study reports on a male adolescent with intracranial hypertension and visual impairment accompanied by DIAM. We present a 16-year-old male patient who after ibuprofen consumption displayed headache, fever, photophobia, and blurred vision following heavy exercises. Examination of cerebrospinal fluid showed a mononuclear pleocytosis and an increase in protein concentration. Other examinations had normal results. The development of common clinical signs following ibuprofen use reflected DIAM. The patient’s vision was found to improve with supportive care and stopping of the drug during follow-up. Given the widespread use of nonsteroidal anti-inflammatory drugs and the fact that these drugs are the most common cause of DIAM, the probability of occurrence of this event should be always kept in mind, and screening for autoimmune diseases in these patients is of great importance.


Sign in / Sign up

Export Citation Format

Share Document