scholarly journals Chromium-Cobalt Intoxication with Intense Systemic Complications following Total Hip Revision after Per-Operative Ceramic Fracture

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Paul Lecoanet ◽  
Mathias Blangis ◽  
Matthieu Garcia ◽  
Yohan Legallois ◽  
Thierry Fabre
Keyword(s):  
Heavy Metal ◽  
Case Report ◽  
Revision Surgery ◽  
Hip Revision ◽  
Systemic Complications ◽  
Ceramic Fracture ◽  
Ceramic Components ◽  
Systemic Symptoms ◽  
Heavy Metal Intoxication ◽  
Rapid Regression

Introduction. Heavy metal intoxication after arthroplasty is extremely rare but could be lethal. Case Report. We report the case of a 69-year-old woman, who presented intense systemic symptoms of chromium-cobalt intoxication after revision of per-operative fractured ceramic components with metal-on-polyethylene. Systemic toxicity occurred a year after surgery and expressed brutally with mostly central neurological symptoms. Chelation associated with revision surgery allowed rapid regression of all symptoms. Conclusion. Revision of fractured ceramic, even per-operatively, should not be done with metal-on-polyethylene components, in order to avoid potentially lethal metal intoxication.

scholarly journals Heavy metal intoxication compromises the host cytokine response in Ascaris Suum model infection

2016 ◽  
Vol 53 (1) ◽  
pp. 14-23 ◽  
Author(s):  
E. Dvorožňáková ◽  
M. Dvorožňáková ◽  
J. Šoltys
Keyword(s):  
Heavy Metal ◽  
Immune Response ◽  
Ascaris Suum ◽  
Cytokine Response ◽  
Parasitic Infections ◽  
Tnf Α ◽  
Ifn Γ ◽  
High Level ◽  
Larval Burden ◽  
Heavy Metal Intoxication

SummaryLead (Pb), Cadmium (Cd) and Mercury (Hg) are recognized for their deleterious effect on the environment and immunity where subsequently compromised immune response affects the susceptibility to the potential parasitic infections. This study examined the host cytokine response after heavy metal intoxication (Pb, Cd, and Hg) and subsequent Ascaris suum infection in BALB/c mice. Pb modulated murine immune response towards the Th2 type of response (delineated by IL-5 and IL-10 cytokine production) what was also dominant for the outcome of A. suum infection. Chronic intoxication with Pb caused a more intensive development of the parasite infection. Cd stimulated the Th1 immune response what was associated with increase in IFN-γ production and reduction of larvae present in the liver of intoxicated mice. The larval burden was also low in mice intoxicated with Hg. This was probably not related to the biased Th1/Th2 type of immune response, but rather to the bad host conditions caused by mercury toxicity and high level of pro-cachectic cytokine TNF-α.

scholarly journals Acute Iodine Toxicity from a Suspected Oral Methamphetamine Ingestion

2014 ◽  
Vol 7 ◽  
pp. CCRep.S20086 ◽  
Author(s):  
Marilyn N. Bulloch
Keyword(s):  
Case Report ◽  
Gastrointestinal Symptoms ◽  
Liver Function Tests ◽  
Oral Ingestion ◽  
Methamphetamine Abuse ◽  
Normal Limits ◽  
Naturally Occurring ◽  
History Of ◽  
Systemic Symptoms ◽  
Iodine Toxicity

Background Iodine is a naturally occurring element commercially available alone or in a multitude of products. Iodine crystals and iodine tincture are used in the production of methamphetamine. Although rarely fatal, iodine toxicity from oral ingestion can produce distressing gastrointestinal symptoms and systemic symptoms, such as hypotension and tachycardia, from subsequent hypovolemia. Objective The objective of this case report is to describe a case of iodine toxicity from suspected oral methamphetamine ingestion. Case Report A male in his early 20′s presented with gastrointestinal symptoms, chills, fever, tachycardia, and tachypnea after orally ingesting a substance suspected to be methamphetamine. The patient had elevated levels of serum creatinine, liver function tests, and bands on arrival, which returned to within normal limits by day 4 of admission. Based on the patient's narrow anion gap, halogen levels were ordered on day 3 and indicated iodine toxicity. This is thought to be the first documented case of iodine toxicity secondary to suspected oral methamphetamine abuse. Conclusion Considering that the incidence of methamphetamine abuse is expected to continue to rise, clinicians should be aware of potential iodine toxicity in a patient with a history of methamphetamine abuse.

Rhabdomyolysis in a Female Caucasian Adolescent Distance Runner: A Case Report

2016 ◽  
Vol 21 (6) ◽  
pp. 26-32 ◽  
Author(s):  
R. Mitchell Todd ◽  
Michelle Cleary ◽  
J. Susan Griffith
Keyword(s):  
Case Report ◽  
Laboratory Testing ◽  
Heat Stroke ◽  
Distance Runner ◽  
Heat Illness ◽  
Adolescent Female ◽  
Systemic Symptoms ◽  
Return To Competition

We present the case of an adolescent female collegiate distance runner competing in her first 6K race. She presented with multiple systemic symptoms of dizziness, nausea, confusion, muscle cramping, and syncope. The patient was immediately treated for heat stroke and, on follow-up, reported to the AT with a headache, lack of appetite, muscle aches, and dark-colored urine. Rhabdomyolysis should be considered following a heat illness event with necessary treatments performed immediately. Symptomatic patients must be referred to a physician for evaluation and laboratory testing. We present recommendations for a supervised return-to-participation protocol and acclimatization to safely return to competition readiness.

Probable cutaneous loxoscelism with mild systemic symptoms: A case report from Spain

Toxicon ◽  
2018 ◽  
Vol 156 ◽  
pp. 7-12 ◽  
Author(s):  
Koen Jerusalem ◽  
Miguel Salavert Lletí
Keyword(s):  
Case Report ◽  
Systemic Symptoms

scholarly journals Synchronous Unicentric Castleman Disease and Inflammatory Hepatocellular Adenoma: a Case Report

2018 ◽  
Vol 17 (5) ◽  
pp. 0-10
Author(s):  
Claudio De Vito ◽  
Thomas Papathomas G. ◽  
Federica Pedica ◽  
Pauline Kane ◽  
Ali Amir ◽  
...  
Keyword(s):  
Case Report ◽  
Ct Scan ◽  
Histological Examination ◽  
Plasma Cell ◽  
Hepatocellular Adenoma ◽  
Castleman Disease ◽  
Cell Type ◽  
Aa Amyloidosis ◽  
Plasma Cell Type ◽  
Systemic Symptoms

Systemic symptoms such as fever and fatigue are non-specific manifestations spanning from inflammation to neoplasia. Here we report the case of a 34 year-old man who presented with systemic symptoms for four months. CT-scan and MRI revealed a 3.4 cm arterialized hepatic lesion and a 7 cm paraduodenal mass. Surgical resection of both lesions and histological examination revealed an inflammatory hepatocellular adenoma and a unicentric plasma cell type of Castleman disease. Moreover, a diffuse AA amyloid deposition in the liver was observed. Resection of both lesions was associated with an improvement of the symptoms. To our knowledge, this is the first report of a synchronous presentation of a unicentric plasma cell type of Castleman disease, inflammatory hepatocellular adenoma and AA amyloidosis.

scholarly journals Total hip revision with custom-made spacer and prosthesis: A case report

2021 ◽  
Vol 9 (25) ◽  
pp. 7605-7613
Author(s):  
Yang-Bo Liu ◽  
Hao Pan ◽  
Li Chen ◽  
Hao-Nan Ye ◽  
Cong-Cong Wu ◽  
...  
Keyword(s):  
Case Report ◽  
Hip Revision ◽  
Total Hip ◽  
Custom Made

scholarly journals Haemorrhagic suprarenal pseudocysts: a systematic review of a rare condition from family physicians’ perspective during the COVID-19 global pandemic

2021 ◽  
Vol 3 (1) ◽  
pp. 22-25
Author(s):  
Adekunle Olowu ◽  
Adel Abbas Alzehairy
Keyword(s):  
Case Report ◽  
Primary Care Physicians ◽  
Rare Condition ◽  
Index Patient ◽  
Management Algorithm ◽  
Global Pandemic ◽  
Surgical Expertise ◽  
Systemic Symptoms ◽  
Specific Symptoms

Adrenal cysts are rare lesions that could be epithelial, endothelial, parasitic or haemorrhagic[1], as well as pseudocysts. Haemorrhagic adrenal cysts are extremely rare and are often asymptomatic, so diagnosis can be really challenging. This can prove really difficult for primary care physicians who are often the frontline clinicians these patients tend to present to. They are usually benign lesions and do not often cause mortality if detected early and prompt surgery is done, as was the case with the patient in our case report[4]. When they do become symptomatic, they can present with different systemic symptoms as documented in literature, including in our case report[2,4]. Diagnosis is usually through Ultrasound and CT Scan and management is largely laparoscopic or open excision depending on the size of the lesion, surgical expertise and local protocol. Most patients make full recovery and mortality is extremely low [3]. The aim of this review is to provide a broader overview of the subject, highlight salient points in several studies relating to haemorrhagic cysts, provide an up to date follow up information on the index patient in our case report and to explore possible areas for future study [4,6]. This review also includes a suggested management algorithm and intends to emphasize the fact that patients who present in primary, urgent or emergency care settings with persistent non-specific symptoms should be investigated for rare diseases.

Sign in / Sign up

Export Citation Format

Share Document