scholarly journals Extensive Circumferential Heterotopic Ossification Discovered at the Base of a Loop Ileostomy

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Ahmad Bosaily ◽  
John Edminister ◽  
Samarchitha Magal ◽  
Mohammad Jamil ◽  
Amy Lynn ◽  
...  

Heterotopic ossification is a rare phenomenon defined by the formation of bone within nonossifying soft tissues. A rare variant of heterotopic ossification is heterotopic mesenteric ossification (HMO), in which there is involvement of the mesentery and surrounding intra-abdominal structures. There are only four previously reported cases of HMO involving an ileostomy. We present a case of HMO affecting an ileostomy which was discovered during elective stoma reversal in a 52-year-old male who required fecal diversion following perineal necrotizing fasciitis.

2020 ◽  
Vol 63 (5) ◽  
pp. 26-30
Author(s):  
Paloma Pérez Ladrón de Guevara ◽  
Georgina Cornelio Rodríguez ◽  
Oscar Quiroz Castro

Fournier’s Gangrene is a type II necrotizing fascitis that leads to thrombosis of small subcutaneous vessels and spreads through the perianal and genital regions and the skin of the perineal. Most cases have a perianal or colorectal focus and in a smaller proportion it originates from the urogenital tract. The mortality rate varies between 7.8 and 50%1-3, only timely diagnosis decreases the morbidity and mortality of this condition. Treatment includes surgical debridement of all necrotic tissue and the use of broad-spectrum antibiotics. Key words: Fournier’s gangrene; gangrene; necrotizing fasciitis; infectious necrotizing of soft tissues.


2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Song Ho Chang ◽  
Takumi Matsumoto ◽  
Koichi Okajima ◽  
Masashi Naito ◽  
Jun Hirose ◽  
...  

Heterotopic ossification (HO) is an ectopic formation of the lamellar bone in the soft tissues. Some authors have previously reported HO or calcific tendinitis of the peroneus longus tendon at the level of the cuboid bone, while the HO of the peroneus longus tendon in the retromalleolar portion has not been reported. The purpose of this report is to describe clinical, radiological, and histological features of this rare ossification and its treatment. To the best of our knowledge, this is the first report presenting a case of HO of the peroneus longus tendon, which developed in the retromalleolar portion.


2014 ◽  
Vol 8 (5-6) ◽  
pp. 462
Author(s):  
Haytham Kamel ◽  
Mohamed Soliman Edris Awed ◽  
Ahmed Fouad Kotb

Necrotizing fasciitis is a progressive, rapidly spreading, inflammatory infection located in deep fascia. It may cause necrosis of skin and subcutaneous tissue and can even result in involvement of adjacent soft tissues such as muscles resulting in necrotizing myositis. We report the case of an adult male presenting with necrotizing myofasciitis secondary to left pyelonephritis. We also review the relevant literature.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Wenjing Jin ◽  
Xianfeng Lin ◽  
Haihua Pan ◽  
Chenchen Zhao ◽  
Pengcheng Qiu ◽  
...  

AbstractOsteoclasts (OCs), the only cells capable of remodeling bone, can demineralize calcium minerals biologically. Naive OCs have limitations for the removal of ectopic calcification, such as in heterotopic ossification (HO), due to their restricted activity, migration and poor adhesion to sites of ectopic calcification. HO is the formation of pathological mature bone within extraskeletal soft tissues, and there are currently no reliable methods for removing these unexpected calcified plaques. In the present study, we develop a chemical approach to modify OCs with tetracycline (TC) to produce engineered OCs (TC-OCs) with an enhanced capacity for targeting and adhering to ectopic calcified tissue due to a broad affinity for calcium minerals. Unlike naive OCs, TC-OCs are able to effectively remove HO both in vitro and in vivo. This achievement indicates that HO can be reversed using modified OCs and holds promise for engineering cells as “living treatment agents” for cell therapy.


1994 ◽  
Vol 167 (5) ◽  
pp. 519-522 ◽  
Author(s):  
Robert E.H. Khoo ◽  
Max M. Cohen ◽  
Georgina M. Chapman ◽  
Daryl A. Jenken ◽  
James M. Langevin

2018 ◽  
Vol 4 ◽  
pp. 2513826X1775405
Author(s):  
Natasha M. MacInnis ◽  
Joshua A. Gillis ◽  
Justin Paletz

Heterotopic ossification (HO), the formation of ectopic lamellar bone in soft tissues, is often reported in the literature as a result of trauma, orthopaedic procedures, burns, or neurological injury. One previous case describes finding HO within a Dupuytren contracture. As this finding was during a surgical case, no preoperative images were captured. We report a case of a 61-year-old male who demonstrated HO of the left fifth digit on radiography, intraoperatively, and confirmed by histology.


2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Rudolf Mennigen ◽  
Britta Heptner ◽  
Norbert Senninger ◽  
Emile Rijcken

Aim. To evaluate the results of temporary fecal diversion in colorectal and perianal Crohn’s disease.Method. We retrospectively identified 29 consecutive patients (14 females, 15 males; median age: 30.0 years, range: 18–76) undergoing temporary fecal diversion for colorectal (n=14), ileal (n=4), and/or perianal Crohn’s disease (n=22). Follow-up was in median 33.0 (3–103) months. Response to fecal diversion, rate of stoma reversal, and relapse rate after stoma reversal were recorded.Results. The response to temporary fecal diversion was complete remission in 4/29 (13.8%), partial remission in 12/29 (41.4%), no change in 7/29 (24.1%), and progress in 6/29 (20.7%). Stoma reversal was performed in 19 out of 25 patients (76%) available for follow-up. Of these, the majority (15/19, 78.9%) needed further surgical therapies for a relapse of the same pathology previously leading to temporary fecal diversion, including colorectal resections (10/19, 52.6%) and creation of a definitive stoma (7/19, 36.8%). At the end of follow-up, only 4/25 patients (16%) had a stable course without the need for further definitive surgery.Conclusion. Temporary fecal diversion can induce remission in otherwise refractory colorectal or perianal Crohn’s disease, but the chance of enduring remission after stoma reversal is low.


Author(s):  
Yorkin Azizov ◽  
Alisher Ohunov

This is an experimental study of lung morphology in modeling sepsis on a background of severe purulent-inflammatory disease of soft tissues (necrotizing fasciitis) by original authors’ method. The study showed that early stages of sepsis (1-3 days) were characterized by manifestations of changes in lung tissue as vascular response, in the second period (the 7th day) by appearance and growth of non-obstructive microatelectases, whereas the third period (the 14th day) was characterized by progression of purulent-necrotic processes in soft tissues, development of surgical sepsis and acute respiratory distress syndrome. These changes in morphological structure of lung tissue are specific for generalized septic process and consequences of necrotizing fasciitis with its septic complication.


2008 ◽  
Vol 55 (3) ◽  
pp. 67-71 ◽  
Author(s):  
Z. Krivokapic ◽  
S. Bilali

Objective: Low pelvic anastomoses are associated with a high leak rate. Loop ileostomies are commonly performed during ileoanal and coloanal anastomoses. This study was undertaken to review our experience with loop ileostomy closure after low anterior rectal resection and restorative proctocolectomy. Patients and methods: One hundred sixty five patients undergoing loop ileostomy closure at a single institution after coloanal and ileoanal anastomoses for rectal carcinoma (n=148) ulcerative colitis (n=9) and FAP (n=8) from January 2003 to December 2006. Fecal diversion was maintained for a mean 13,5 weeks. Results: Of the 165 patients, 100 were male and 65 female with mean age 59 (range 23-83 years). Overall, complication rate was 10,9 per cent. The common complication were sub occlusion six patients, occlusion three patients, wound infection eight patients and abdominal sepsis one patient. Complications required operative management in four cases. There was no mortality related to ileostomy. Conclusion: The study shown that ileostomy closure is a safe and effective with generally minor complications and should be considered as a safe alterative for fecal diversion.


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