scholarly journals Use of Autologous Platelets for Lamellar Macular Hole Repair

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Andres Gonzalez ◽  
Sarina Amin ◽  
Omar Iqbal ◽  
Stephen Myles Potter ◽  
Syed Gibran Khurshid

The consensus of lamellar macular hole repair generally entails vitrectomy with internal limiting membrane with/without epiretinal membrane peeling with gas tamponade, although the risk of a full thickness macular hole remains. In this case report, we investigate the role of the regenerative properties of autologous platelets in the repair of a lamellar macular hole with pars plana vitrectomy, an autologous platelet plug, and 12% C3F8 without prone posturing. All three patients in this case report experienced visual improvement along with anatomic closure of the lamellar macular hole. Further randomized studies with larger sample sizes will contribute to the existing data regarding this procedure and its outcomes.

2021 ◽  
Author(s):  
Debdulal Chakraborty ◽  
Dipankar Das ◽  
Begum Sabiha Mashuda Khanam

Abstract Spontaneous reattachment of rhegmatogenous retinal detachment (SRRRD) is a rare presentation. A macular hole coexisting in a patient with a SRRRD is rarer still. The authors describe a case of SRRRD with a macular hole presenting with decreased vision which has never been described before in scientific literature. The patient underwent vitrectomy with internal limiting membrane peeling and gas tamponade, leading to type I closure of the macular hole and subsequent visual improvement.


2016 ◽  
Vol 7 (6) ◽  
pp. 43-46
Author(s):  
Lalit Agarwal ◽  
Nisha Agrawal ◽  
Pratap Karki ◽  
Abhishek Anand

Background:  A macular hole is a full-thickness defect of retinal tissue involving the anatomic fovea, thereby affecting central visual acuity. Pars plana vitrectomy and gas tamponade is a recognised modality of treatment for macular hole.Larger holes are more likely to remain open after repair and late reopening after an initially closed macular hole is seen in macular holes larger than 400 μm.Aims and Objective: To evaluate the anatomical and functional outcome of pars plana vitrectomy with internal limiting membrane peeling for chronic stage 3 macular hole.Materials and Methods: Records of 15 patients with stage 3 chronic macular holes operated from 1st January 2013 to 30th June 2013 and completed 1 year of follow up were retrospectively evaluated and included in the study. Preoperative best distance corrected visual acuity (BCVA), preoperative macular hole size, final BCVA and macular hole status at 1 year follow up were recorded. Macular hole closure and visual improvement was calculated. Correlation of macular hole closure and visual improvement with various macular hole parameter was estimated.Results: Eleven (73.3%) macular holes closed at 1 year follow-up. Mean BCVA improved from 1.2 ± 0.27 to 0.89 ± 0.36 logarithm of minimum angle of resolution at 1 year (p<0.001). Visual improvement was seen in only eight (53.3%) eyes. Both macular hole closure and visual improvement showed no correlation with minimum linear diameter, base diameter and hole height.Conclusion: Chronic stage 3 macular hole can be closed successfully in majority of patients with fairly good visual improvement. Macular hole parameters of stage 3 holes may not have any correlation with the anatomical and visual outcome.Asian Journal of Medical Sciences Vol.7(6) 2016 43-46


2018 ◽  
Vol 9 (2) ◽  
pp. 199-202
Author(s):  
Rajya Laxmi Gurung

The exact pathogenesis of macular hole (MH) is controversial with most of the cases being idiopathic. Trauma is an important cause of secondary MH formation. MH post Pars Plana Vitrectomy (PPV) is an even rare entity with only a handful of cases reported so far ( Kumagai et al, 2008; Smiddy W.E, 1993; Kimura et al, 2005). An even rarer event is spontaneous closure of post PPV full thickness macular hole (FTMH), though spontaneous closure of traumatic macular hole (TMH) has been reported before. Herein, we report a 26 year old male patient who developed FTMH post PPV that closed spontaneously.


2021 ◽  
pp. 363-368
Author(s):  
Mizuki Ikeda ◽  
Takayuki Baba ◽  
Yuri Aikawa ◽  
Jiro Yotsukura ◽  
Hirotaka Yokouchi ◽  
...  

We report a case of ocular toxoplasmosis that developed a full-thickness macular hole (FTMH) which was successfully treated by pars plana vitrectomy combined with an inverted internal limiting membrane (ILM) flap. A 49-years-old Japanese man was aware of blurred vision in his right eye. Slit-lamp biomicroscopy, ophthalmoscopy, and optical coherence tomography (OCT) of the right eye showed that there was a grayish-white subretinal lesion at the macula accompanied by retinal exudation and mild vitreous flare and iritis. An increase in the level of serum IgM for toxoplasma led to a diagnosis of ocular toxoplasmosis. He developed a FTMH adjacent to the lesion 2 weeks after administering sulfamethoxazole/trimethoprim, and his decimal visual acuity was 0.15. Because the FTMH remained 3 months after the resolution of inflammation and his metamorphopsia persisted, vitrectomy with an inverted ILM flap was performed. After the surgery, the visual acuity improved to 0.2 with the closure of the FTMH confirmed by OCT. A FTMH in an eye with ocular toxoplasmosis was successfully closed by vitrectomy with an inverted ILM flap.


2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Dominika Wrzesińska ◽  
Katarzyna Nowomiejska ◽  
Dominika Nowakowska ◽  
Agnieszka Brzozowska ◽  
Teresio Avitabile ◽  
...  

Purpose. To examine the relationship between the morphological and functional results in eyes after pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling due to stage 4 full-thickness macular hole (FTMH). Methods. The study included 22 eyes that underwent successful PPV due to FTMH. Both vertical metamorphopsia (VM) and horizontal metamorphopsia (HM) were determined using type 2 M-charts, as well as best-corrected visual acuity (BCVA), microperimetry, and optical coherence tomography (OCT) were performed before PPV and 1 and 6 months postoperatively. Results. A significant improvement of BCVA and metamorphopsia scores measured by M-charts in particular periods before surgery, 1 and 6 months after PPV, was observed. The VM scores were consistently higher than the HM scores at all assessment times. There was a correlation found between VM and BCVA and microperimetry parameters before surgery. The macular sensitivity (MS) as well as macular integrity index increased from 1 month to 6 months after PPV and were correlated with postoperative visual acuity (VA). There was a correlation found between the hole diameter and MS and P2 parameter 6 months after PPV. There was a correlation found between mean duration of symptoms of FTMH and VA and VM score. Conclusions. VM scores seem to correlate better than HM scores with preoperative BCVA, microperimetry parameters, and duration of symptoms of the FTMH. VM scores are higher after PPV than HM scores in patients with stage 4 of the FTMH. This trial is registered with NCT03701542.


2017 ◽  
Vol 6 (2) ◽  
pp. 391-395
Author(s):  
Christina Garnavou-Xirou ◽  
Tina Xirou ◽  
Stamatina Kabanarou ◽  
Ilias Gkizis ◽  
Stavros Velissaris ◽  
...  

2021 ◽  
Vol 14 (1) ◽  
pp. e238604
Author(s):  
Nikita Gupta ◽  
Aditi Mehta ◽  
Mohit Dogra ◽  
Simar Rajan Singh

A 70-year-old woman presented with sudden decrease of vision 2 months following a successful vitrectomy with inverted internal limiting membrane flap for a full thickness macular hole. Serial review of fundus pictures and optical coherence tomography scans revealed a focal retinal pigment epithelial disruption at the site of the macular hole after surgery and a choroidal neovascular membrane arising from the same. This report describes the possible role of the surgical technique in causation of the membrane and discusses modifications to avoid the same.


2018 ◽  
Vol 9 (1) ◽  
pp. 119-125 ◽  
Author(s):  
Yumi Iwakawa ◽  
Hisanori Imai ◽  
Hiromi Kaji ◽  
Yuki Mori ◽  
Chihiro Ono ◽  
...  

Purpose: To report a case of macular hole (MH) secondary to a retinal arterial macroaneurysm (RAMA) which was successfully treated with an autologous transplantation of internal limiting membrane (ILM). Case Report: An 87-year-old female presented with a sudden decrease in central vision in the right eye. A fundus examination revealed a RAMA in the superonasal macular region, a subretinal hemorrhage (SRH), involving the macula, and a sub-ILM hemorrhage. A pars plana vitrectomy (PPV) was performed. Intraoperatively, an MH filled with coagulum was detected. We tried to blow off and drain the SRH with a current of BSS and a gentle suction with a 27-gauge vitreous cutter from the MH, but some amount of SRH at the bottom of the MH remained. The ILM was peeled off for 2 disc diameters around the MH. The vitreous cavity was filled with air at the end of the operation. Two weeks after the surgery, the MH was not closed. One month following the initial PPV, a second PPV was performed to achieve closure of the MH. Results: An autologous transplantation of ILM was performed as second PPV. Six months after the final surgery, the MH was successfully closed and the best-corrected decimal visual acuity was 0.6. Conclusions: Autologous ILM transplantation can be an effective treatment option for MH closure following RAMA rupture.


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