scholarly journals Endosonographic Findings and the Natural Course of Chronic Gastric Anisakiasis: A Single-Center Experience

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
Eun Young Park ◽  
Dong Hoon Baek ◽  
Gwang Ha Kim ◽  
Bong Eun Lee ◽  
So-Jeong Lee ◽  
...  
Keyword(s):  
Muscularis Propria ◽  
University Hospital ◽  
Eosinophil Infiltration ◽  
Tubular Structures ◽  
High Power Field ◽  
Mesenchymal Tumors ◽  
Single Center Experience ◽  
National University ◽  
Raw Fish

Background. Chronic gastric anisakiasis is a rare, usually asymptomatic, and difficult to diagnose infection incidentally discovered during endoscopy, resembling a subepithelial tumor (SET). Because its endoscopic ultrasonography (EUS) findings are not established, it is occasionally misdiagnosed as gastrointestinal mesenchymal tumors and removed by endoscopic or surgical resection. We aimed to assess the characteristic EUS findings of chronic gastric anisakiasis and the clinical course during follow-up. Methods. The database of all patients who underwent EUS at Pusan National University Hospital (Busan, Korea) between January 2011 and December 2016 was retrospectively analyzed. A total of 28 SET cases with EUS features suggesting chronic gastric anisakiasis were included in the study. The EUS, histopathologic, and follow-up endoscopic features were analyzed. Results. On EUS, the lesions were mainly located in the submucosal and/or propria muscle layers. Twenty-seven lesions (27/28, 96%) showed hypoechoic echogenicity, and 22 lesions (22/28, 79%) were heterogeneous. Hyperechoic tubular structures suggesting denaturalized Anisakidae larvae were seen in 22 lesions (22/28, 79%). Endoscopic biopsies revealed significant eosinophil infiltration (≥30 per high-power field) in 12 lesions (12/21, 57%). During the median follow-up period of 9 months (range, 1–55 months), SETs decreased or subsided in 26 lesions (26/28, 93%) with no change in the size of the two lesions (2/28, 7%). Conclusions. Chronic gastric anisakiasis, although rare, should be included in the differential diagnoses for gastric SETs, especially in regions where raw fish is widely consumed. EUS findings suggesting chronic gastric anisakiasis are heterogeneously hypoechoic lesions with hyperechoic tubular structures, mainly in the submucosal and/or muscularis propria layers. Because chronic gastric anisakiasis decreases or subsides in most cases, follow-up endoscopy 6–12 months later is recommended.

scholarly journals Prognostic Factors for Radiographic Progression in Patients with Seronegative Rheumatoid Arthritis

2021 ◽  
Vol 11 (3) ◽  
pp. 184
Author(s):  
Eun-Jung Park ◽  
WooSeong Jeong ◽  
Jinseok Kim
Keyword(s):  
Rheumatoid Arthritis ◽  
Prognostic Factors ◽  
Radiographic Progression ◽  
Linear Regression Analysis ◽  
University Hospital ◽  
Symptom Duration ◽  
Radiographic Damage ◽  
National University ◽  
Yearly Change

(1) Background: It has long been suggested that seronegative rheumatoid arthritis (RA) represents a clinical entity quite distinct from that of seropositive. However, analytical studies of seronegative RA dedicated to clinical outcomes regarding radiographic progression and related risk factors are scarce. The aim of this study is to evaluate radiographic outcome and prognostic factors for radiographic progression in patients with seronegative rheumatoid arthritis. (2) Methods: Subjects included RA patients reported as seronegative for both rheumatoid factor and anti-citrullinated protein antibody, who were treated at Jeju National University Hospital in South Korea between 2003 and 2016, including follow-up of at least 2 years. All patients fulfilled 1987 ACA or 2010 ACR/EULAR RA criteria. Radiographic progression was measured by yearly change in the Sharp van der Heijde (SvdH) score during follow-up periods. Medical records, laboratory and radiographic data were retrospectively analyzed, and linear regression analysis was performed to evaluate prognostic factors for radiographic progression in patients with seronegative rheumatoid arthritis. (3) Results: In total, 116 patients with seronegative RA were observed and 43 (37.1%) patients demonstrated radiographic damage during follow-up period. Mean age at diagnosis was 48 years and 86 (74.1%) patients were female. Symptom duration at diagnosis was 1.3 years and mean follow-up duration was 5.2 years. Patients with radiographic damage at diagnosis were 14 (12.1%) and mean SvdH score was 6.8 at diagnosis. Radiographic damage and SvdH at diagnosis significantly correlated with radiographic progression in patients with seronegative RA after adjusting age, sex, symptom duration, number of active synovitis, and CRP at diagnosis (β-coefficient 6.5 ± 1.84; p = 0.001 and β-coefficient 0.12 ± 0.02; p < 0.001, respectively). (4) Conclusions: This study determined that radiographic damage and SvdH at diagnosis were predictive factors in progression of radiographic damage in patients with seronegative rheumatoid arthritis. A large comparative study dedicated to this issue in seronegative RA is required.

scholarly journals Gastric epithelial dysplasia: Characteristics and long-term follow-up results after endoscopic resection according to morphological categorization.

2015 ◽  
Vol 33 (3_suppl) ◽  
pp. 190-190
Author(s):  
Bong Eun Lee ◽  
Gwang Ha Kim ◽  
Dong Hoon Baek
Keyword(s):  
Endoscopic Resection ◽  
Epithelial Dysplasia ◽  
University Hospital ◽  
Clinicopathologic Characteristics ◽  
Morphologic Characteristics ◽  
Study Results ◽  
National University ◽  
Long Term Follow Up

190 Background: Gastric epithelial dysplasia (GED) can be morphologically categorized into adenomatous and foveolar types. To date, there have been few studies on the clinical characteristics of GEDs according to the morphologic types. Therefore, we here aimed to elucidate the clinicopathologic characteristics of patients with GED and the long-term follow-up results after endoscopic resection according to the morphologic characteristics of GEDs. Methods: A total of 357 patients who underwent endoscopic resection for GEDs at Pusan National University Hospital between January 2008 and December 2009 were included in the study. Results: Patients with GED were divided into 3 groups: adenomatous (n = 167, 46.8%), foveolar (n = 103, 28.9%), and hybrid (n = 87, 24.3%) types. Compared to the adenomatous type, foveolar type lesions were more frequently located in the antrum/pylorus, flat/depressed lesions, and normal/reddish in color; and showed more frequent high-grade dysplasia. During the follow–up period (median, 37.3 months), the overall incidence of synchronous and metachronous lesions was 20.8% and 20.1%, respectively; of these, the incidence of synchronous and metachronous gastric cancer was 8.7% and 5.4%, respectively. There were no significant differences in the incidence of synchronous and metachronous lesions according to morphologic types. Conclusions: GEDs appear to have different clinicopathologic characteristics according to morphologic types. Irrespective of the morphology, synchronous and metachronous gastric cancers are commonly found after endoscopic resection of GEDs. Therefore, close follow-up surveillance after endoscopic resection of GEDs should be performed for all patients.

scholarly journals Natural Course of Fat Necrosis After Breast Reconstruction: A 10-Year Follow-Up Study

2020 ◽  
Author(s):  
Jeeyeon Lee ◽  
Ho Yong Park ◽  
Wan Wook Kim ◽  
Jeong Ju Lee ◽  
Hee Jung Keum ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Reconstruction ◽  
Natural Course ◽  
University Hospital ◽  
Excision Biopsy ◽  
Fat Necrosis ◽  
Total Mastectomy ◽  
Clinicopathologic Characteristics ◽  
National University

Abstract Background: Although fat necrosis is a minor postoperative complication after breast reconstruction, occasionally it mimics to tumor recurrence in patients with breast cancer. Therefore, the surgeon should distinguish between benign fat necrosis and true local recurrence. The authors evaluated the clinical characteristics of fat necrosis after breast reconstruction and investigated the natural course of fat necrosis.Methods: Between 2007 and 2013, a total of 362 patients underwent breast reconstruction after partial or total mastectomy for breast cancer in Kyungpook National University Hospital. Clinicopathologic characteristics and the occurrence of fat necrosis were assessed during surveillance for 10 years of mean follow-up period.Results: There were 42 cases (11.6 %) of fat necrosis after breast reconstruction with partial or total mastectomy which were confirmed by needle or excision biopsy. The fat necrosis was resolved after a mean period of 45.9 months (SD, ± 42.1) and 26 cases (61.9 %) of fat necrosis were almost completely resolved (less than 5 mm) during 10-year follow-up period.Conclusion: Based on the natural course of fat necrosis, the fat necrosis after breast reconstruction can be only monitored, if pathologic confirmation was done. More than half of the cases will be resolved within 2–3years.

scholarly journals Natural course of fat necrosis after breast reconstruction: a 10-year follow-up study

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jeeyeon Lee ◽  
Ho Yong Park ◽  
Wan Wook Kim ◽  
Jeong Ju Lee ◽  
Hee Jung Keum ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Reconstruction ◽  
Natural Course ◽  
University Hospital ◽  
Excision Biopsy ◽  
Fat Necrosis ◽  
Total Mastectomy ◽  
Clinicopathologic Characteristics ◽  
National University

Abstract Background Although fat necrosis is a minor postoperative complication after breast reconstruction, occasionally it mimics to tumor recurrence in patients with breast cancer. Therefore, the surgeon should distinguish between benign fat necrosis and true local recurrence. The authors evaluated the clinical characteristics of fat necrosis after breast reconstruction and investigated the natural course of fat necrosis. Methods Between 2007 and 2013, a total of 362 patients underwent breast reconstruction after partial or total mastectomy for breast cancer in Kyungpook National University Hospital. Clinicopathologic characteristics and the occurrence of fat necrosis were assessed during surveillance for 10 years of mean follow-up period. Results There were 42 cases (11.6%) of fat necrosis after breast reconstruction with partial or total mastectomy which were confirmed by needle or excision biopsy. The fat necrosis was resolved after a mean period of 45.9 months (SD, ± 42.1) and 26 cases (61.9%) of fat necrosis were almost completely resolved (less than 5 mm) during 10-year follow-up period. Conclusion Based on the natural course of fat necrosis, the fat necrosis after breast reconstruction can be only monitored, if pathologic confirmation was done. More than half of the cases will be resolved within 2–3 years.

scholarly journals Intraosseus Arteriovenous Malformation of the Mandible: Extracorporeal Curettage and Immediate Replantation

2019 ◽  
Vol 34 (1) ◽  
pp. 56-59
Author(s):  
Erik A. Tongol ◽  
Alfredo Q.Y. Pontejos ◽  
Phillip B. Fullante ◽  
Arsenio Claro A. Cabungcal ◽  
Kimberly Mae C. Ong
Keyword(s):  
Arteriovenous Malformation ◽  
Arteriovenous Malformations ◽  
University Hospital ◽  
New Bone Formation ◽  
Surgical Services ◽  
Early Results ◽  
National University ◽  
Design Case ◽  
And Function

Objective: To describe a surgical technique in the treatment of arteriovenous malformations of the mandible Methods:        Design:    Case Report        Setting:    Tertiary National University Hospital        Participants:        One Result: A 16-year-old boy underwent resection, extracorporeal curettage, and immediate replantation of the hemimandible for intraosseous arteriovenous malformation. Postoperative follow up and imaging at one- and six-months showed no signs of recurrence, new bone formation and consolidation of the replanted right mandible with good symmetry and function. Conclusion: Extracorporeal curettage followed by immediate replantation of the resected mandible seems to have yielded good early results in our case and may be a viable alternative especially when access to highly specialized microvascular surgical services is limited. Keywords: arteriovenous malformation; mandible, abnormalities; extracorporeal curettage

scholarly journals The Effect of a Simple Phone Call Intervention on FIT-Positive Individuals: An Exploratory Study

2020 ◽  
Author(s):  
Gretel Jianlin Wong ◽  
Jerrald Lau ◽  
Ker-Kan Tan
Keyword(s):  
Patient Outcomes ◽  
University Hospital ◽  
Phone Call ◽  
Telephone Intervention ◽  
Preliminary Screening ◽  
National University ◽  
Study Team ◽  
Immunochemical Test ◽  
Improve Patient

Purpose: Colorectal cancer (CRC) screening has been shown to improve patient outcomes. A widely utilised preliminary screening tool is the Faecal Immunochemical Test (FIT). However, follow-up rates after a positive FIT result remain suboptimal. Methods: In order to improve the compliance of FIT-positive individuals to follow-up consultation and to elucidate barriers to action, a simple 5- to 10-minute telephone intervention with a structured script based on the Protection Motivation Theory (PMT) was conducted. Results: Ninety-two FIT-positive individuals who had previously rejected follow-up consultation in the National University Hospital, Singapore were interviewed by the study team. Individuals reported barriers to action such as the denial of a positive FIT result (41.8%) and a lack of knowledge (34.5%). More than 20% of the participants who had yet to schedule follow-up consultation changed their minds after the intervention. Conclusion: The results suggest that a simple, structured telephone call can potentially encourage more FIT-positive individuals to pursue follow-up investigation.

scholarly journals Outcomes and Complications of Scleral-Fixated Intraocular Lens Combined with Ahmed Tube Surgery

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
Nikhel Sachdev ◽  
Maria Cecilia Aquino ◽  
Seng Chee Loon ◽  
Yiong Huak Chan ◽  
Paul Chew ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Intraocular Lens ◽  
Pressure Control ◽  
University Hospital ◽  
Posterior Chamber ◽  
Bullous Keratopathy ◽  
Increased Risk ◽  
Posterior Chamber Intraocular Lens ◽  
National University

Background. To evaluate the outcome and complications of transscleral suture-fixated posterior chamber intraocular lens (PCIOL) implantation combined with Ahmed glaucoma valve (AGV) surgery in Asian eyes. Design. This was a retrospective study that included 22 eyes from 22 participants. The surgeries were performed at Singapore’s National University Hospital. Participants underwent an Ahmed tube surgery, together with transscleral suture-fixated posterior chamber intraocular lens. Main Outcome Measures. Complete success was defined as 6 ≤ intraocular pressure (IOP) ≤ 21 mmHg without medications at the last follow-up visit, with no reoperation required and no progression to no perception of light (NPL). Results. At the last follow-up, there was a significant reduction in mean IOP (22.4 ± 6.5 mmHg versus 13.9 ± 3.9 mmHg; p<0.001) and mean number of intraocular pressure-lowering medications (2.45 ± 1.30 versus 0.05 ± 0.21; p<0.001). There was no significant change in visual acuity [1.43 ± 1.21 (LogMAR) versus 1.09 ± 1.31 (p=0.204)]. Sixteen eyes (72.7%) achieved complete success. The 3 commonest complications were bullous keratopathy, choroidal detachment, and displacement of intraocular lens. Conclusion and Relevance. This technique showed good success for intraocular pressure control and vision preservation. Postoperative complications were relatively common although most were self-limiting. Patients at increased risk of trabeculectomy failure may be suitable for this procedure.

scholarly journals Clinical and Laboratory Characteristics of Kikuchi-Fujimoto Disease According to Age

2021 ◽  
Vol 9 ◽  
Author(s):  
Hye-Young Kim ◽  
Ha Young Jo ◽  
Seong Heon Kim
Keyword(s):  
Sex Ratio ◽  
Recurrence Rate ◽  
Clinical Features ◽  
University Hospital ◽  
Laboratory Findings ◽  
Number Of Patients ◽  
National University ◽  
Male Sex ◽  
Age And Sex

Background: Little information exists regarding the differences in the clinical and laboratory characteristics of Kikuchi-Fujimoto disease (KFD) according to age.Objective: To evaluate the clinical and laboratory characteristics of KFD according to age.Methods: The relevance of sex, age, clinical features, laboratory findings, courses, and follow-up results were retrospectively evaluated in patients diagnosed with KFD at Pusan National University Hospital between 2010 and 2020.Results: Eighty patients (46 children and 34 adults) with a mean age of 21.5 ± 11.8 years (range, 3–49 years) were included in the study. Those aged 10–19 years accounted for the largest number of patients (42.5%). Among children, the male sex ratio was higher, especially for patients aged ≤ 9 years. In adults, the female sex ratio was higher, especially for patients aged 20–29 years. Fever, tenderness in the lymph node, and skin rashes were more common in children, while myalgia and weight loss were more common in adults. In children, the recurrence rate was significantly higher among boys than among girls (15.8 vs. 0.0%, P = 0.001); lower platelet count and higher CRP levels were observed among boys than among girls. EBV and ANA positivity rates were higher in boys than in girls. In adults, the recurrence rate was significantly higher in women than in men (18.2 vs. 0.0%, P = 0.005). ANA positivity rates were higher in women than in men.Conclusion: The clinical features, laboratory findings, and recurrence of KFD may differ depending on age and sex. Clinicians should be aware of this.

scholarly journals Left Atrial Appendage Closure for Stroke Prevention

2021 ◽  
pp. 22-24
Author(s):  
Evan Kimber
Keyword(s):  
Patient Selection ◽  
Stroke Prevention ◽  
Left Atrial ◽  
Left Atrial Appendage ◽  
Atrial Appendage ◽  
University Hospital ◽  
Left Atrial Appendage Closure ◽  
National University ◽  
Procedural Planning

IMPLEMENTING an effective patient-selection approach, integrating device choice, procedural planning, and patient follow-up, have proven crucial to the success of left atrial appendage closure (LAAC) therapy for atrial fibrillation (AF). This was the focus of the EuroPCR 2021 ‘Structural Theatre’ session, which compared LAAC and direct oral anticoagulant (DOAC) treatment avenues for stroke prevention. In this session, Patrick Calvert, from Royal Papworth Hospital in Cambridge, UK, gave a presentation on patient selection, alongside Ole De Backer of Copenhagen University Hospital, Denmark, who discussed device selection and planning using CT imagery. Ivan Kuntjoro, from the National University Heart Centre of Singapore, briefly outlined left atria morphology, and Farell Hellig of Sunninghill Hospital, Johannesburg, South Africa, introduced procedural plans in a step-by-step approach while performing a live procedure. The session was concluded by Edgar Tay, UK Royal College of Physicians, who gave his insights on several of these topics and concluded the stream with how to optimise patient follow-up care.

Sign in / Sign up

Export Citation Format

Share Document