scholarly journals The Relationship between Multiple Myeloma with Renal Failure and Metastatic Calcification

2018 ◽  
Vol 2018 ◽  
pp. 1-6
Author(s):  
Takanori Fukuta ◽  
Takayuki Tanaka ◽  
Yoshinori Hashimoto ◽  
Hiromi Omura
Keyword(s):  
Multiple Myeloma ◽  
Renal Failure ◽  
Blood Vessels ◽  
Hormone Level ◽  
Maintenance Hemodialysis ◽  
Metastatic Calcification ◽  
The Right ◽  
End Stage ◽  
The Relationship ◽  
Tomography Scan

While cases of multiple myeloma (MM) with metastatic calcification have been reported, the mechanisms for this calcification have yet to be explained. We observed a case of MM in a patient with end-stage renal failure who developed vascular and pulmonary calcification. A 51-year-old male was diagnosed with Bence-Jones type MM and required maintenance hemodialysis. He was treated with bortezomib-dexamethasone, vincristine-doxorubicin-dexamethasone, the M2 protocol, and lenalidomide-dexamethasone (Rd) therapy. During the sixth cycle of Rd therapy, he complained of pain in both lower legs. Well-demarcated ulcers with severe pain had developed on the right lower leg, both exterior thighs, and penis. We found that the patient’s serum intact parathyroid hormone level was elevated, while it had previously been permissively controlled. Computed tomography scan showed widespread centrilobular opacities of the bilateral lungs and high-density lesions along small blood vessels in the trunk and all four extremities. Histological calcifications were identified in small blood vessels and the alveolar walls. The risk of metastatic calcification in MM appears to be associated with renal failure, but not with MM itself.

scholarly journals Myeloma multiplex with pulmonary dissemination

2014 ◽  
Vol 71 (6) ◽  
pp. 596-599 ◽  
Author(s):  
Brankica Terzic ◽  
Djoko Maksic ◽  
Vesna Skuletic ◽  
Dejan Pilcevic ◽  
Mirjana Mijuskovic ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Renal Failure ◽  
Plasma Cells ◽  
Lung Parenchyma ◽  
Clonal Proliferation ◽  
Loss Of Weight ◽  
General Weakness ◽  
Uncommon Disease ◽  
The Right ◽  
End Stage

Introduction. Multiple myeloma is a hemathological malignancy characterized by the clonal proliferation of plasma cells in the bone the marrow. Extramedullary dissemination of multiple myeloma is uncommon. In several cases only, the multiple myeloma malignant plasma cells had diseminated to the lung parenchyma. Case report. We presented a case of multiple myeloma with lung plasmacytoma, in a 79-year-old patient, hospitalized for febrility and infiltrative mass in the right lung. Two months before the patient was admitted, because of developing terminal renal failure, hemodialysis treatment had started three times a week. Since then, the patient was oliguric, but because of febrility and hemoptysis that appeared, at first he was treated with dual antibiotic therapy which resulted in temporary improvement of his general condition, but pleural effusion remained. After thoracocentesis, followed by myelogram, the multiple myeloma diagnosis was established. Conclusion. In patients of middle and older age, with general weakness, exhaustion, loss of weight, renal failure which progresses to the end stage rapidly, if symptoms of respiratory tract occur, consider this uncommon disease - extramedullary dissemination of multiple myeloma.

“Dialysis and medical tourism. Investigating patients’ perceptions in Greece”

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Vasiliki Traouda ◽  
Panagiotis Mpogiatzidis
Keyword(s):  
Renal Failure ◽  
Kidney Disease ◽  
Quantitative Research ◽  
Medical Tourism ◽  
Renal Dialysis ◽  
Artificial Kidney ◽  
Daily Routine ◽  
Content Type ◽  
The Right ◽  
End Stage

Purpose The purpose of this paper is to explore the possibilities and the growth prospects of medical tourism in Greece, while particularly focusing on the dialysis process. Patients with end-stage renal failure have the right to any treatment deemed necessary during their journey to another city or country away from the place where their treatment normally takes place. Design/methodology/approach The survey has been conducted among 193 kidney disease patients that underwent extra-renal dialysis in two public and three private artificial kidney units in Thessaloniki. The study population consists of patients with end-stage chronic renal failure (CRF) that undergo dialysis. For the purpose of this study, quantitative research was carried out via a structured and anonymous questionnaire. The design and structure of the study were based upon questionnaires from two relevant questionnaires. The questionnaires were modified appropriately to respond to the subject in question. Finally, for the analysis of the data, the SPSS software has been used. Findings One of the most obvious results is that patients on dialysis treatment have limited both the frequency and the duration of their vacation. The 8.3% of patients that did not use to travel increased to 37.8%, whereas only 22.3% continue to travel 2–4 times a year. Patients that keep on going on vacation frequently claim that a break from the daily routine improves their quality of life. Most of the participants (up to 36.3%) claim they feel healthier, while 34.2% stated they experience a normal life when they escape their everyday life and travel far from home. The 69.9% claim that Greece has the potentials to be a popular medical tourism destination. However, a well-structured and government-financed assistance programme is absent. The processing of data has revealed a positive correlation between age and tourism behaviour. Additionally, according to the research results, younger patients tend to be better informed regarding medical tourism in comparison with older ones. Social implications Considering the patients to be potential travellers facilitates the development, realization and promotion of medical tourism. Originality/value This study attempts to investigate, for the first time, the tourism behaviour of chronic kidney disease patients. The study highlights a sensitive issue, patients’ right to treatment without geographical or distance-related obstacles.

scholarly journals Acute Intradialytic Complications in End Stage Renal Disease on Maintenance Hemodialysis

2012 ◽  
Vol 52 (187) ◽  
Author(s):  
R K Agrawal ◽  
S Khakurel ◽  
R Hada ◽  
D Shrestha ◽  
A Baral
Keyword(s):  
Renal Failure ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Maintenance Hemodialysis ◽  
Care Hospital ◽  
Cross Sectional ◽  
Stage Renal Disease ◽  
End Stage

Introduction: Hemodialysis is the preferred method of treatment for Nepalese patients with End Stage Renal Disease. Despite the technological advances and better understanding of physiology associated with hemodialysis, a number of complications are known to be associated with hemodialysis. This study was undertaken to study the frequency of acute intradialytic complications in patients undergoing hemodialysis. Methods: A cross-sectional study was conducted at Nephrology unit of a tertiary care hospital from 15 June, 2007 to 15 December, 2007. A total of 28 patients were included in the study. Patients with acute renal failure and acute on chronic renal failure were excluded from the study. Results: Total sessions of hemodialysis during the period were 1455. Hypotensive episode were 66 (4.5%) and was the commonest complication and followed by hypertensive episodes were 58 (3.8%). Other problems encountered were transfusion reactions were 23 episodes (1.5%), rigors not related to transfusions were 13 episodes (0.8%), nausea/vomiting were 20 episodes (1.4%), muscle cramps were 12 episodes (0.8%), hypoglycemia were 6 episodes 5(0.4%). Conclusions: The frequency of intradialytic complications is low and many of them are not life threatening. Keywords: complications; end stage renal disease; hemodialysis; hypertension; hypotension.

scholarly journals Renal angiomyolipomatosis and bleeding aneurysms in a tuberous sclerosis context: selective artery embolization in a girl with end-stage renal failure

2020 ◽  
Vol 12 (2) ◽  
Author(s):  
Gloria Pelizzo ◽  
Mario Giuseppe Vallone ◽  
Mario Milazzo ◽  
Gregorio Rosone ◽  
Salvatore Amoroso ◽  
...  
Keyword(s):  
Renal Failure ◽  
Peritoneal Dialysis ◽  
Tuberous Sclerosis ◽  
Therapeutic Option ◽  
Endovascular Embolization ◽  
End Stage Renal Failure ◽  
Renal Aneurysm ◽  
Recent Developments ◽  
The Right ◽  
End Stage

Recent developments in endovascular radiological techniques and devices have rendered embolization a major therapeutic option prior to surgery in many renal vascular or neoplastic diseases. A 19-yearold female patient, with a diagnosis of tuberous sclerosis complex (TSC) in childhood, was admitted with severe anemia. Polycystic kidney disease in end-stage renal failure appeared four years before and the patient has been undergoing peritoneal dialysis. The patient’s medical history also included bilateral renal angiomyolipomas (AMLs). One year earlier, a unilateral endovascular embolization was performed to repair a bleeding aneurysm at the right renal upper pole. A second bilateral ruptured renal aneurysm was diagnosed at admission. To continue with peritoneal dialysis and prevent intrarenal hemorrhage and intraperitonal bleeding, an urgent bilateral renal AE was performed. Two months later she underwent a bilateral retroperitoneal nephrectomy. The posterior surgical approach, preserved the peritoneal surface area and adequate conditions to continue dialysis. At histology, bilateral AMLs were confirmed and a renal cell carcinoma of the right kidney was concurrently discovered. She undergoes continuous peritoneal dialysis. Urgent selective renal AE represents a feasible treatment for bilateral AML bleeding. It is safe and feasible before performing nephrectomy in patients with end-stage renal failure.

Efficacy of diet therapy in patients with end-stage uremia undergoing maintenance hemodialysis

1980 ◽  
Vol 61 (6) ◽  
pp. 26-28
Author(s):  
M. A. Samsonov ◽  
V. M. Ermolenko ◽  
S. A. Agadjanov
Keyword(s):  
Renal Failure ◽  
Body Weight ◽  
Clinical Observation ◽  
Diet Therapy ◽  
Maintenance Hemodialysis ◽  
End Stage Renal Failure ◽  
End Stage

Based on biochemical analyzes and clinical observation of 32 patients with end-stage renal failure on maintenance hemodialysis, a special 7G diet was developed, containing 60 g of protein (0.9-1.0 g per 1 kg of the patient's body weight) and the physiological norm of vitamins and minerals. substances.

Metastatic Calcification of the True Vocal Cords as a Cause of Hoarseness

1994 ◽  
Vol 103 (11) ◽  
pp. 849-851 ◽  
Author(s):  
Robert B. Belser ◽  
David W. Stepnick ◽  
Sabouh Setrakian ◽  
Donald E. Hricik
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Soft Tissue ◽  
End Stage Renal Disease ◽  
Soft Tissue Calcification ◽  
Vocal Cords ◽  
True Vocal Cord ◽  
Metastatic Calcification ◽  
Stage Renal Disease ◽  
End Stage

Visceral soft tissue calcification is common in patients with end-stage renal disease. However, metastatic calcification of the true vocal cords has not been described. We present a patient with chronic renal failure and hoarseness in whom an exophytic true vocal cord mass was diagnosed as a metastatic calcification.

scholarly journals Helicobacter pylori status and esophagogastroduodenal mucosal lesions in patients with end-stage renal failure on maintenance hemodialysis

2010 ◽  
Vol 45 (5) ◽  
pp. 515-522 ◽  
Author(s):  
Tomohiko Moriyama ◽  
Takayuki Matsumoto ◽  
Katsuya Hirakawa ◽  
Hirofumi Ikeda ◽  
Kazuhiko Tsuruya ◽  
...  
Keyword(s):  
Renal Failure ◽  
Helicobacter Pylori ◽  
Maintenance Hemodialysis ◽  
End Stage Renal Failure ◽  
Mucosal Lesions ◽  
End Stage
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