scholarly journals Increased Zinc Serum Level: New Clues in Babol Stroke Patients, Northern Iran

2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Alijan Ahmadi Ahangar ◽  
Payam Saadat ◽  
Sona Niroomand ◽  
Shayan Alijanpour ◽  
Reza Sohrabnezhad ◽  
...  
Keyword(s):  
Heart Disease ◽  
Serum Level ◽  
Ischemic Heart Disease ◽  
Serum Levels ◽  
Ischemic Heart ◽  
Control Group ◽  
Stroke Patients ◽  
Northern Iran ◽  
The Difference

Background. Stroke is the second leading cause of death worldwide. The role of zinc as a new predictor of stroke was considered. Methods. This prospective study was conducted in Ayatollah Rouhani Hospital within a year on 100 stroke and 100 control patients. Findings. The difference in zinc serum level in two groups was significant (deficiency: 3 (3%) in patients versus 20 (20%) in control group, normal: 25 (25%) versus 54 (54%), and increased level: 72 (72%) versus 26 (26%); p<0.001). Difference in zinc serum levels was statistically significant with ischemic heart disease (deficiency: 0 cases (0%), normal: 8 cases (24%), increased level: 24 cases (75%), p=0.003). Increases in zinc serum level were significantly correlated with the frequency of hemorrhagic and ischemic patients (deficiency: 3 (3.3%) hemorrhagic versus 0 (0%) ischemic; normal: 19 (21%) versus 6 (60%), increased level: 68 (75.6%) versus 4 (40%); p=0.025). Regression logistics showed that ischemic heart disease (p<0.001; OR = 28.29, %95 CI: 5.53; 144.87), hyperlipidemia (p<0.001; OR = 0.26, %95 CI: 0.12; 0.56), and zinc serum level (p<0.001, OR = 15.53, %95 CI: 4.03; 59.83) each had a significant role. Conclusions. Babol stroke patients are prone to increased zinc serum level as a new parameter. Ischemic heart disease, increased levels of zinc, and hyperlipidemia were found to be probable predictor factors for stroke in Babol.

scholarly journals Zinc Serum Level Can Be a Risk Factor In Babol Stroke Patients?

2017 ◽  
pp. 10 ◽  
Author(s):  
Alijan AhmadiAhangar ◽  
Payam Saadat ◽  
Fatemeh Arab ◽  
Alireza Firozejahi ◽  
Mohamad Ali Biani ◽  
...  
Keyword(s):  
Risk Factor ◽  
Serum Level ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Zinc Level ◽  
Control Group ◽  
Stroke Patients ◽  
Cross Sectional ◽  
The Difference ◽  
And Control

Background and Purpose: Stroke is the second leading cause of death worldwide. The role of zinc as a contributing factor in the pathogenesis of stroke was considered.Results: This cross-sectional study on 100 stroke patients in Ayatollah Rouhani Hospital and 100 control group from cohort master plan "Ageing and health projects Amirkola was conducted. Zinc levels Serum simultaneously with other blood tests in the early hours of hospitalization. Zinc serum level was defined 70 to 120 micrograms per deciliter.Findings: The difference in mean of zinc level in patients and control group was not significant (102.6±47.7 in control group vs 100.9±35.8 in patient, p=0.7). Difference in zinc Serum level had statically significant with IHD (under70 0 cases (0), 70 to120 8 cases (24), 120 and upper24 cases (75), p=0.003) and with type of stroke (under70 (3(3.3) hemorrhagic vs 0(0) ischemic), 70 to 120(19(21) vs6 (60)), 120 and upper68 (75.6) vs4 (40), p=0.025) and also with patient and control group (under70 (3(3) in patient's vs 20(20) control group), 70 to 120(25(25) vs54 (54)), 120 and upper72 (72) vs26 (26), p<0001). In patients group 72(73.5) of cases had zinc serum level above 120. HLP difference was significant in patient and control group (50(50) in control group vs 35(35) in patients, p=0.04). Regression logistic show that IHD (p<0001, OR=30, CI=6-152), HLP (p<0001, OR=4, CI=9.09-1.85), zinc serum level (p<0001, OR=15.5, CI=4-59.8) had significant role.Conclusions: Zinc serum levels, Ischemic Heart Disease, Hyperlipidemia were most risk factor that play role in Babol stroke patients.

scholarly journals Association of MCP-1 -2518 A/G Single Nucleotide Polymorphism with the Serum Level of CRP in Slovak Patients with Ischemic Heart Disease, Angina Pectoris, and Hypertension

2009 ◽  
Vol 2009 ◽  
pp. 1-6 ◽  
Author(s):  
Maria Bucova ◽  
Jan Lietava ◽  
Peter Penz ◽  
Frantisek Mrazek ◽  
Jana Petrkova ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Heart Disease ◽  
Angina Pectoris ◽  
Serum Level ◽  
Ischemic Heart Disease ◽  
Healthy Subjects ◽  
Serum Levels ◽  
Control Group ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide

The aim of our work was to find if MCP-1 -2518 (A/G) single nucleotide polymorphism (SNP) influences somehow the serum concentrations of high-sensitive CRP (hsCRP) both in patients suffering from ischemic heart disease (IHD), myocardial infarction (MI), angina pectoris (AP), and hypertension (HT) and in control group of healthy subjects. Totally, 263 patients with the diagnosis of IHD, out of them 89 with MI, 145 with AP, 205 with HT, and also 67 healthy subjects were included in the study. First, we estimated the serum levels of hsCRP. We found that patients with AP had significantly higher serum level of hsCRP than both control group of healthy subjects (P=.043) and IHD patients without AP (P=.026). The presence of the mutant G allele statistically significantly correlated with the higher serum levels of hsCRP in patients with IHD (P=.016), AP (P=.004), and HT (P=.013). Higher correlations were found in men (AP:P=.019; HT:P=.047). In all cases the highest levels of hsCRP were found both in patients and healthy controls with homozygous GG genotype.

Serum otolin-1 as a biomarker for benign paroxysmal positional vertigo: a case-control study

2021 ◽  
pp. 1-4
Author(s):  
D V K Irugu ◽  
A Singh ◽  
H Yadav ◽  
H Verma ◽  
R Kumar ◽  
...  
Keyword(s):  
Serum Level ◽  
Benign Paroxysmal Positional Vertigo ◽  
Case Control Study ◽  
Serum Levels ◽  
Case Control ◽  
Control Group ◽  
Positional Vertigo ◽  
The Difference ◽  
Control Study ◽  
Paroxysmal Positional Vertigo

Abstract Objectives This study aimed to evaluate serum otolin-1 levels in patients with benign paroxysmal positional vertigo and to compare these levels with healthy individuals. Method This was a case-control study. After obtaining institutional ethical committee clearance, the serum level of otolin-1 was calculated in adult individuals (18–75 years old) who were divided into group 1 (patients presenting with benign paroxysmal positional vertigo) and group 2 (healthy patients without benign paroxysmal positional vertigo as the control group). Data analysis was carried out to compare the serum levels in the cases and controls. A p-value less than 0.05 was considered significant. Results A total of 70 age-matched individuals (cases, n = 40; controls, n = 30) were included in the study. The mean serum level of otolin-1 was 636.8 pg/ml (range, 259–981 pg/ml) in the group of patients with benign paroxysmal positional vertigo and 236.2 pg/ml (range, 189–370 pg/ml) in the control group. The difference was statistically significant (p = 0.0000). Conclusion The serum levels of otolin-1 in patients with benign paroxysmal positional vertigo are significantly higher compared with individuals without benign paroxysmal positional vertigo.

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