scholarly journals The Role of Dendritic Cells in the Differentiation of T Follicular Helper Cells

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Xueyang Zou ◽  
Guangyu Sun ◽  
Feifei Huo ◽  
Lu Chang ◽  
Wei Yang

T follicular helper cells (TFH) are a subset of recently discovered CD4+ T cells. Their major function is to participate in the formation of germinal centres (GCs) and promote B cell proliferation and differentiation to play important roles in the production of antibodies. Currently, the functions of TFH cells are clear. However, the early differentiation of these cells is not clear. Dendritic cells (DCs) participate in the differentiation of TFH cells. Therefore, this article reviewed the research progress regarding the influence of DCs on the differentiation of TFH cells and their major underlying mechanisms.

Cell Reports ◽  
2015 ◽  
Vol 11 (12) ◽  
pp. 1929-1940 ◽  
Author(s):  
Changsik Shin ◽  
Jae-A Han ◽  
Hyein Koh ◽  
Bongseo Choi ◽  
Yongbin Cho ◽  
...  

2017 ◽  
Vol 8 ◽  
Author(s):  
John Patrick Thornhill ◽  
Sarah Fidler ◽  
Paul Klenerman ◽  
John Frater ◽  
Chansavath Phetsouphanh

2017 ◽  
Vol 199 (8) ◽  
pp. 2624-2629 ◽  
Author(s):  
Ryuta Kamekura ◽  
Kenichi Takano ◽  
Motohisa Yamamoto ◽  
Koji Kawata ◽  
Katsunori Shigehara ◽  
...  

Immunity ◽  
2009 ◽  
Vol 31 (3) ◽  
pp. 491-501 ◽  
Author(s):  
Helena Cucak ◽  
Ulf Yrlid ◽  
Boris Reizis ◽  
Ulrich Kalinke ◽  
Bengt Johansson-Lindbom

2013 ◽  
Vol 92 (1) ◽  
pp. 22-27 ◽  
Author(s):  
André Ballesteros‐Tato ◽  
Troy D Randall

JCI Insight ◽  
2019 ◽  
Vol 4 (11) ◽  
Author(s):  
Bethany L. Dale ◽  
Arvind K. Pandey ◽  
Yuhan Chen ◽  
Charles D. Smart ◽  
Fanny Laroumanie ◽  
...  

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