scholarly journals A Feasible Computational Fluid Dynamics Study for Relationships of Structural and Functional Alterations with Particle Depositions in Severe Asthmatic Lungs

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Sanghun Choi ◽  
Shinjiro Miyawaki ◽  
Ching-Long Lin

This study aims to investigate the effect of altered structures and functions in severe asthma on particle deposition by using computational fluid dynamics (CFD) models. Airway geometrical models of two healthy subjects and two severe asthmatics were reconstructed from computed tomography (CT) images. Subject-specific flow boundary conditions were obtained by image registration to account for regional functional alterations of severe asthmatics. A large eddy simulation (LES) model for transitional and turbulent flows was applied to simulate airflows, and particle transport simulations were then performed for 2.5, 5, and 10 μm particles using CFD-predicted flow fields. Compared to the healthy subjects, the severe asthmatics had a smaller air-volume change in the lower lobes and a larger air-volume change in the upper lobes. Both severe asthmatics had smaller airway circularity (Cr), but one of them had a significant reduction of hydraulic diameter (Dh). In severe asthmatics, the larger air-volume change in the upper lobes resulted in more particles in the upper lobes, especially for the small 2.5 μm particles. The structural alterations measured by Cr and Dh were associated with a higher particle deposition. Dh was found to be the most important metric which affects the specific location of particle deposition. This study demonstrates the relationship of CT-based structural and functional alterations in severe asthma with flow and particle dynamics.

Author(s):  
Blake W. Lance ◽  
Jeff R. Harris ◽  
Barton L. Smith

Model validation for computational fluid dynamics (CFD), where experimental data and model outputs are compared, is a key tool for assessing model uncertainty. In this work, mixed convection was studied experimentally for the purpose of providing validation data for CFD models with a high level of completeness. Experiments were performed in a facility built specifically for validation with a vertical, flat, heated wall. Data were acquired for both buoyancy-aided and buoyancy-opposed turbulent flows. Measured boundary conditions (BCs) include as-built geometry, inflow mean and fluctuating velocity profiles, and inflow and wall temperatures. Additionally, room air temperature, pressure, and relative humidity were measured to provide fluid properties. Measured system responses inside the flow domain include mean and fluctuating velocity profiles, temperature profiles, wall heat flux, and wall shear stress. All of these data are described in detail and provided in tabulated format.


2013 ◽  
Vol 368-370 ◽  
pp. 619-623
Author(s):  
Zhen Liu ◽  
Xiao Ling Wang ◽  
Ai Li Zhang

For the purpose of avoiding the deficiency of the traditional construction ventilation, the ventilation of the underground main powerhouse is simulated by the computational fluid dynamics (CFD) to optimize ventilation parameters. A 3D unsteady RNG k-ε model is performed for construction ventilation in the underground main powerhouse. The air-flow field and CO diffusion in the main powerhouse are simulated and analyzed. The two construction ventilation schemes are modelled for the main powerhouse. The optimized ventilation scheme is obtained by comparing the air volume and pressure distributions of the different ventilation schemes.


2021 ◽  
Vol 2059 (1) ◽  
pp. 012003
Author(s):  
A Burmistrov ◽  
A Raykov ◽  
S Salikeev ◽  
E Kapustin

Abstract Numerical mathematical models of non-contact oil free scroll, Roots and screw vacuum pumps are developed. Modelling was carried out with the help of software CFD ANSYS-CFX and program TwinMesh for dynamic meshing. Pumping characteristics of non-contact pumps in viscous flow with the help of SST-turbulence model were calculated for varying rotors profiles, clearances, and rotating speeds. Comparison with experimental data verified adequacy of developed CFD models.


2021 ◽  
Vol 2053 (1) ◽  
pp. 012013
Author(s):  
N. Abdul Settar ◽  
S. Sarip ◽  
H.M. Kaidi

Abstract Wells turbine is an important component in the oscillating water column (OWC) system. Thus, many researchers tend to improve the performance via experiment or computational fluid dynamics (CFD) simulation, which is cheaper. As the CFD method becomes more popular, the lack of evidence to support the parameters used during the CFD simulation becomes a big issue. This paper aims to review the CFD models applied to the Wells turbine for the OWC system. Journal papers from the past ten years were summarized in brief critique. As a summary, the FLUENT and CFX software are mostly used to simulate the Wells turbine flow problems while SST k-ω turbulence model is the widely used model. A grid independence test is essential when doing CFD simulation. In conclusion, this review paper can show the research gap for CFD simulation and can reduce the time in selecting suitable parameters when involving simulation in the Wells turbine.


Author(s):  
Alessandro Corvaglia ◽  
Giorgio Altare ◽  
Roberto Finesso ◽  
Massimo Rundo

Abstract In this paper, two 3D CFD models of a load sensing proportional valve are contrasted. The models were developed with two different software, Simerics PumpLinx® and ANSYS Fluent®. In both cases the mesh was dynamically modified based on the fluid forces acting on the local compensator. In the former, a specific template for valves was used, in the latter a user-defined function was implemented. The models were validated in terms of flow rate and pressure drop for different positions of the main spool by means of specific tests. Two configurations were tested: with the local compensator blocked and free to regulate. The study has brought to evidence the reliability of the CFD models in evaluating the steady-state characteristics of valves with complex geometry.


Energies ◽  
2019 ◽  
Vol 12 (12) ◽  
pp. 2438 ◽  
Author(s):  
Vojtěch Turek

The ability to model fluid flow and heat transfer in process equipment (e.g., shell-and-tube heat exchangers) is often critical. What is more, many different geometric variants may need to be evaluated during the design process. Although this can be done using detailed computational fluid dynamics (CFD) models, the time needed to evaluate a single variant can easily reach tens of hours on powerful computing hardware. Simplified CFD models providing solutions in much shorter time frames may, therefore, be employed instead. Still, even these models can prove to be too slow or not robust enough when used in optimization algorithms. Effort is thus devoted to further improving their performance by applying the symmetric successive overrelaxation (SSOR) preconditioning technique in which, in contrast to, e.g., incomplete lower–upper factorization (ILU), the respective preconditioning matrix can always be constructed. Because the efficacy of SSOR is influenced by the selection of forward and backward relaxation factors, whose direct calculation is prohibitively expensive, their combinations are experimentally investigated using several representative meshes. Performance is then compared in terms of the single-core computational time needed to reach a converged steady-state solution, and recommendations are made regarding relaxation factor combinations generally suitable for the discussed purpose. It is shown that SSOR can be used as a suitable fallback preconditioner for the fast-performing, but numerically sensitive, incomplete lower–upper factorization.


Author(s):  
Jian-Xun Wang ◽  
Christopher J. Roy ◽  
Heng Xiao

Proper quantification and propagation of uncertainties in computational simulations are of critical importance. This issue is especially challenging for computational fluid dynamics (CFD) applications. A particular obstacle for uncertainty quantifications in CFD problems is the large model discrepancies associated with the CFD models used for uncertainty propagation. Neglecting or improperly representing the model discrepancies leads to inaccurate and distorted uncertainty distribution for the quantities of interest (QoI). High-fidelity models, being accurate yet expensive, can accommodate only a small ensemble of simulations and thus lead to large interpolation errors and/or sampling errors; low-fidelity models can propagate a large ensemble, but can introduce large modeling errors. In this work, we propose a multimodel strategy to account for the influences of model discrepancies in uncertainty propagation and to reduce their impact on the predictions. Specifically, we take advantage of CFD models of multiple fidelities to estimate the model discrepancies associated with the lower-fidelity model in the parameter space. A Gaussian process (GP) is adopted to construct the model discrepancy function, and a Bayesian approach is used to infer the discrepancies and corresponding uncertainties in the regions of the parameter space where the high-fidelity simulations are not performed. Several examples of relevance to CFD applications are performed to demonstrate the merits of the proposed strategy. Simulation results suggest that, by combining low- and high-fidelity models, the proposed approach produces better results than what either model can achieve individually.


2015 ◽  
Vol 73 (5) ◽  
pp. 969-982 ◽  
Author(s):  
Edward Wicklein ◽  
Damien J. Batstone ◽  
Joel Ducoste ◽  
Julien Laurent ◽  
Alonso Griborio ◽  
...  

Computational fluid dynamics (CFD) modelling in the wastewater treatment (WWT) field is continuing to grow and be used to solve increasingly complex problems. However, the future of CFD models and their value to the wastewater field are a function of their proper application and knowledge of their limits. As has been established for other types of wastewater modelling (i.e. biokinetic models), it is timely to define a good modelling practice (GMP) for wastewater CFD applications. An International Water Association (IWA) working group has been formed to investigate a variety of issues and challenges related to CFD modelling in water and WWT. This paper summarizes the recommendations for GMP of the IWA working group on CFD. The paper provides an overview of GMP and, though it is written for the wastewater application, is based on general CFD procedures. A forthcoming companion paper to provide specific details on modelling of individual wastewater components forms the next step of the working group.


2014 ◽  
Vol 117 (6) ◽  
pp. 593-603 ◽  
Author(s):  
Sanghun Choi ◽  
Eric A. Hoffman ◽  
Sally E. Wenzel ◽  
Mario Castro ◽  
Ching-Long Lin

Lung air trapping is estimated via quantitative computed tomography (CT) using density threshold-based measures on an expiration scan. However, the effects of scanner differences and imaging protocol adherence on quantitative assessment are known to be problematic. This study investigates the effects of protocol differences, such as using different CT scanners and breath-hold coaches in a multicenter asthmatic study, and proposes new methods that can adjust intersite and intersubject variations. CT images of 50 healthy subjects and 42 nonsevere and 52 severe asthmatics at total lung capacity (TLC) and functional residual capacity (FRC) were acquired using three different scanners and two different coaching methods at three institutions. A fraction threshold-based approach based on the corrected Hounsfield unit of air with tracheal density was applied to quantify air trapping at FRC. The new air-trapping method was enhanced by adding a lung-shaped metric at TLC and the lobar ratio of air-volume change between TLC and FRC. The fraction-based air-trapping method is able to collapse air-trapping data of respective populations into distinct regression lines. Relative to a constant value-based clustering scheme, the slope-based clustering scheme shows the improved performance and reduced misclassification rate of healthy subjects. Furthermore, both lung shape and air-volume change are found to be discriminant variables for differentiating among three populations of healthy subjects and nonsevere and severe asthmatics. In conjunction with the lung shape and air-volume change, the fraction-based measure of air trapping enables differentiation of severe asthmatics from nonsevere asthmatics and nonsevere asthmatics from healthy subjects, critical for the development and evaluation of new therapeutic interventions.


2017 ◽  
Vol 9 (4) ◽  
pp. 157-168 ◽  
Author(s):  
Shahid Rabbani ◽  
Mohamed Sassi ◽  
Tariq Shamim

With the passage of time for chemical operations involving packed-bed reactors, especially in petroleum refining and petrochemical industries, non-filterable fines such as coke, corrosion products and fine clay in oilsands bitumen deposit on the catalyst particles. The gradual entrapment and deposition of fine particles of range 0.7–20 µm cause the pore-plugging phenomenon to occur which consequently blocks the flow passages inside the porous medium. To understand the plugging phenomenon and its effect on hydrodynamic of the reactor, we developed a computational fluid dynamics model which is based on reactor collection efficiency, filtration rate, Brownian motion and interfacial momentum exchange terms to simulate the pressure drop due to deposition of fine particles in real conditions. With the help of this model, we have studied the effect of fines deposition on bed porosity and clogging. This is for the first time that Ansys Fluent has been used to simulate fine-particle deposition in packed-bed conditions. The result was a Eulerian–Eulerian 2-D computational fluid dynamics model which considered all the three phases, i.e. liquid, catalyst and fine particles. The results were validated against the experiments reported in the literature and reached good agreement.


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