scholarly journals Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary Disease

2018 ◽  
Vol 2018 ◽  
pp. 1-6
Author(s):  
Nikolić Emilija ◽  
Nikolić Aleksandar ◽  
Stević Ruža ◽  
Brandmajer Tijana ◽  
Mićanović Veselin ◽  
...  

Introduction. The St. George’s Respiratory Questionnaire (SGRQ), Modified Medical Research Council (mMRC) Dyspnea Scale, Hospital Anxiety and Depression Scale (HADS), and general health questionnaire (SF-36) are widely used for chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD). Aim. We examined the reliability and validity of a modified questionnaire (MQ) to create a model for assessing the health-related quality of life (HRQOL) in COPD. Method. In total, 132 COPD patients completed the MQ. Lung function, smoking index, and exacerbation frequency were measured. Cronbach’s α coefficient of correlation, standard deviation, and multifactorial nonlinear regression analysis were used to verify the internal validity of the MQ and to develop the mathematical model. Results. Female (63) patients had lesser airway obstruction than, and exacerbation frequency similar to that of, male patients. Exacerbation frequency significantly correlated with spirometry parameters in female patients. The MQ total score achieved high internal consistency (Cronbach’s α = 0.89) and showed significant correlations with exacerbation frequency, smoking habit, and spirometry parameters in male patients (p<0.005). Conclusion. The HRQOL questionnaire was shown to be a good indicator of the health status of COPD patients. The mathematical model easily and precisely confirmed the score of HRQOL questionnaire.

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 420
Author(s):  
Nazih Abu Tabar ◽  
Mohammad Al Qadire ◽  
Imad Thultheen ◽  
Jafar Alshraideh

Patients’ with Chronic Obstructive Pulmonary Disease suffer from serious respiratory symptoms that increase anxiety, stress, and uncertainty, and affect quality of life. The aim of this study was to assess level of anxiety, uncertainty, and health related quality of life (HRQoL) among COPD patients in Jordan. Correlational cross-sectional survey design was used to collect data from 153 COPD patients. ‎The study was conducted at pulmonary clinics in three major referral hospitals in Jordan that provide care for COPD patients from different parts of the country. To assess HRQoL, St. George ‎Respiratory Questionnaire‎ was completed. Uncertainty and anxiety level was measured by Mishel's uncertainty of illness scale and state anxiety inventory respectively. The mean age of participants was 66.8 (SD= 10.3) and most participants were males (94.1%) with. The mean score of HRQoL was 57.9 (SD = 20.5). The mean score of participants’ level of anxiety was 38.1 (SD = 11.1). The mean score of uncertainty was 66.1 (SD= 11.1). There is a statistically significant positive relationship between HRQoL and anxiety (r =.433, p< .01), and uncertainty (r=.483, p<.01). Increased anxiety and uncertainty among COPD patients was associated with low HRQoL. Health care providers need to pay attention the effect of anxiety and uncertainty on COPD patients’ quality of life and institute appropriate management.


2015 ◽  
Vol 14 (1) ◽  
pp. 60-68 ◽  
Author(s):  
Dragana Maric ◽  
Dragana Jovanovic ◽  
Ljudmila Nagorni-Obradovic ◽  
Mihailo Stjepanovic ◽  
Darija Kisic-Tepavcevic ◽  
...  

ABSTRACTObjective:Under conditions in which palliative care has not yet become part of clinical practice, the differences in palliative care needs between patients with cancer and other life-limiting diseases can yield knowledge that will be very valuable for future planning. The aim of our investigation was to compare health-related quality of life (HRQoL) for patients with end-stage chronic obstructive pulmonary disease (COPD) and those with non-small-cell lung cancer (NSCLC) in Belgrade, Serbia. We also evaluated the influence of demographic, socioeconomic, and clinical factors on HRQoL for both patient groups.Method:This cross-sectional study included 100 NSCLC patients (stages IIIb and IV) and 100 patients with stage IV COPD. Measures included the SF-36 questionnaire, the EORTC QLQ–C30, the St. George's Respiratory Questionnaire, and the Beck Depression Inventory (BDI). Associations of demographic, socioeconomic, and clinical factors with QoL were examined using linear regression analyses.Results:The COPD group scored significantly lower compared to NSCLC patients in all SF-36 domains except for bodily pain. Additionally, a significantly higher level of depressive symptoms was observed in COPD patients. A worse physical QoL for COPD patients was independently associated with a longer duration of unemployment, a lack of wage earning, lower Karnofsky Performance Status (KPS) scores, and higher levels of depression. A worse mental QoL for COPD patients was related to a longer duration of disease, poorer KPS scores, and higher BDI scores. The independent variables significantly associated with worse physical and mental QoL of NSCLC patients were lower KPS and higher BDI scores.Significance of Results:A worse QoL, a significantly higher level of depressive symptoms, and adverse socioeconomic status in the COPD group imposes the need for development of more intensive psychosocial and community support for COPD patients during implementation of palliative care.


2021 ◽  
pp. 00181-2021
Author(s):  
Cristóbal Esteban ◽  
Inmaculada Arostegui ◽  
Amaia Aramburu ◽  
Javier Moraza ◽  
Myriam Aburto ◽  
...  

Chronic obstructive pulmonary disease (COPD) is understood as a complex, heterogeneous and multisystem airway obstructive disease. The association of deterioration in health-related quality of life (HRQoL) with mortality and hospitalisation for COPD exacerbation has been explored in general terms. The specific objectives of this study were to determine whether a change in HRQoL is related over time with mortality and hospitalisation. Overall, 543 patients were recruited through Galdakao Hospital's five outpatient respiratory clinics. Patients were assessed at baseline and the end of the first and second year and were followed-up for 3 years. At each assessment, measurements were made of several variables, including HRQoL using the Saint George's Respiratory Questionnaire (SGRQ). The cohort had moderate obstruction (FEV1 55% of the predicted value). SGRQ total, symptoms, activity and impact scores at baseline were 39.2, 44.5, 48.7 and 32.0, respectively. Every 4-point increase in the SGRQ was associated with an increase in the likelihood of death: “symptoms” domain odds ratio (OR)=1.04; 95% CI (1.00–1.08); “activity” domain OR=1.12; 95% CI (1.08–1.17) and “impacts” domain OR=1.11; 95% CI (1.06–1.15). The rate of hospitalisations per year was 5% (95% CI 3%-8%) to 7% (95% CI 5%-10%) higher for each 4-point increase in the separate domains of the SGRQ. Deterioration in HRQoL by 4 points in SGRQ domain scores over 1 year was associated with an increased likelihood of death and hospitalisation.


Author(s):  
Boyuk Moradkhani ◽  
Samaneh Mollazadeh ◽  
Parastoo Niloofar ◽  
Afsaneh Bashiri ◽  
Mohammad Bagher Oghazian

Abstract Background Chronic Obstructive Pulmonary Disease (COPD) is one of the prominent cause of mortality worldwide. Nowadays, the level of medication adherence in COPD patients is very low, which reduces the clinical therapeutic effects. The purpose of the present study is to investigate the relationship between medication adherence and Health-Related Quality of Life (HRQoL) in COPD patients referred to the pulmonologist’s office. Methods This observational study was performed on 100 COPD outpatient cases. Each patient was interviewed to answer questionnaires regarding demographic and clinical information. To assess quality of life, health status, and severity of dyspnea, the St George’s Respiratory Questionnaire - COPD-Specific Version (SGRQ-C), COPD Assessment Test (CAT), and Modified British Medical Research Council (mMRC) questionnaires were used, respectively. Persian version of the Morisky Medication Adherence Scale (MMAS-8-Item) was used to measure medication adherence. To determine the adherence predictors, an ordinal logistic regression analysis was performed. Results Out of 100 patients with mean (±SD) age of 61.35 (±10.79) years, 74% had medium and high medication adherence. In the final ordinal logistic model, quality of life, health status, and education level found to have positive effect on medication adherence while polypharmacy had negative effect. We did not find any significant association between age, gender, Body Mass Index (BMI), and other variables with medication adherence. Conclusions Patients with high quality of life are more adherent to their medications. Furthermore, patients who have polypharmacy, tend to have less adherence to their medications.


2017 ◽  
Vol 15 (4) ◽  
pp. 329-338 ◽  
Author(s):  
Hidehiro Irie ◽  
Shotaro Chubachi ◽  
Minako Sato ◽  
Mamoru Sasaki ◽  
Naofumi Kameyama ◽  
...  

Cigarette smoking increases the risk of developing both cataract and chronic obstructive pulmonary disease (COPD). The prevalence of cataract and the clinical characteristics of COPD patients with cataract were retrospectively investigated in a 2-year observational COPD cohort. We analyzed 395 patients with complete data on ophthalmologic evaluation (319 subjects with COPD and 76 subjects at risk of COPD). There was no difference in the prevalence of cataract between COPD patients and those at risk (47.0% vs. 42.1%, p = 0.44). Age ≥ 75 years, low body mass index, and hypertension were independently associated with cataract as a comorbidity in COPD. The incidence of exacerbation within 2 years was significantly higher in COPD patients with cataract than those without cataract (36.6% vs. 18.3%, p = 0.0019). COPD patients with cataract exhibited significantly higher COPD assessment test score compared to those without cataract (13.7 ± 8.9 vs. 11.5 ± 7.2, p = 0.0240). Overall St George’s Respiratory Questionnaire score and each component were significantly worse in COPD patients with cataract compared to those without cataract. COPD patients with cataract exhibited poor health-related quality of life and frequent exacerbations. The association between cataract and exacerbations of COPD deserves further attention.


2021 ◽  
Vol 64 (2) ◽  
pp. 433-443
Author(s):  
Rafael Hurtado-Ruzza ◽  
Óscar Álvarez-Calderón Iglesias ◽  
Ricardo Becerro-de-Bengoa-Vallejo ◽  
César Calvo-Lobo ◽  
Marta San-Antolín ◽  
...  

Purpose The association between voice alterations, health-related quality of life (HRQL), and chronic respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), has previously been reported. The aim of this study was to test the hypothesis that HRQL and dysphonia-associated handicap of patients diagnosed with asthma or COPD are worse than healthy controls. Method A case–control study in which participants were recruited by a consecutive sampling method from a single institution was conducted. Three groups were created: (a) asthma (51 patients), (b) COPD (52 patients), and (c) 50 healthy controls. Self-reported handicap associated with dysphonia was assessed using the 30-item Voice Handicap Index (VHI-30); meanwhile, HRQL was tested via the European Quality of Life (EQ) Questionnaire and the EQ–visual analog scale. Also, aerodynamic assessment applied to phonation was assessed, and maximum phonation time and s/e index were registered. Results VHI scores were higher for asthma and COPD (7.19 ± 8.31 and 11.80 ± 15.18, respectively) than in the control group (3.72 ± 6.78). The EQ index was lower in asthma and COPD patients than in controls. The EQ–visual analog scale showed lower scores in asthma and COPD than in the controls. Conclusions HRQL was worse in COPD patients than in asthma patients. Even though the patient groups showed worse VHI and HRQL scores than the healthy controls, the scores fell within the normal variation range. No significant variations in the maximum phonation time index between groups were noted.


2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Ramune Jacobsen ◽  
Ea Rusch ◽  
Anne Frølich ◽  
Per Kragh Andersen ◽  
Nina Godftredsen

Pulmonary rehabilitation (PR) is a recommended standard of care for patients with chronic obstructive pulmonary disease (COPD), as it improves exercise capacity and health-related quality of life (HRQOL), attenuates perceived dyspnoea, and decreases the need for hospitalisation. The objective of this study was to compare medical and sociodemographic characteristics of COPD patients who were enrolled and completed the PR with those of COPD patients who were resident in the same municipality but were not enrolled into this PR. The data used for comparison came from the Danish National Registers. The COPD patients who were enrolled and completed the rehabilitation differed from COPD patients who were not enrolled into the rehabilitation in the following: (1) there were more women than men among those who were enrolled; (2) those who were enrolled had higher socioeconomic status compared to those who were not enrolled; and (3) those who were enrolled into the rehabilitation used more COPD-specific medication compared to those who were not enrolled. In conclusion, to enrol more COPD patients into PR, special attention needs to be paid to COPD patients from lower socioeconomic status groups as well as male patients.


Author(s):  
Ulfa Nur Rohmah ◽  
Muhammad Amin ◽  
Makhfudli Makhfudli

; [email protected] Makhfudli Fakultas Keperawatan, Universitas Airlangga; [email protected] (koresponden) ABSTRACT Background: Low quality of life in chronic obstructive pulmonary disease is crucial because leads to a high risk to reduced activity of daily and mortality. Objective: To identify determine factors that influence with health-related quality of life on stable COPD patients. Method: The database was performed article from Science Direct, CINAHL, Scopus dan PubMed is limited to the last 5 years of publication from 2014 to 2019, full-text article in English. The keywords used ”Health-Related Quality of Life”, “AND”, “Stable”, “AND”, “COPD”. Results: Fourteen articles with 8401 participants were included in the review. Most studies were cross sectional design. COPD Assasment Test (CAT) was to assess health-related quality of life in stable COPD. There was symptoms and exacerbation, functional capacity exercise, psychology, sociodemography, biomolecular, comorbidity, and pulmonary function affecting health-related quality of life on stable COPD patients. Conclusion: Factors might affect with poor HRQOL because the condition of COPD itself which then give an effect to whole body. Suggestion: Health worker need to be aware and control of the complexity of factors influence health-related quality of life to impove outcomes for COPD patients. Keywords: health-related quality of life; chronic obstructive pulmonary disease ABSTRAK Latar belakang: Kualitas hidup yang rendah pada pasien Penyakit Paru Obstruktif Kronik (PPOK) menjadi penting karena dapat menyebabkan penurunan aktivitas sehari-hari dan kematian. Tujuan: Untuk mengetahui determinan faktor yang dapat mempengaruhi kualitas hidup pasien PPOK yang stabil Metode: Database yang digunakan dalam penelitian ini adalah Science Direct, CINAHL, Scopus dan PubMed terbatas untuk publikasi 5 tahun terakhir dari 2014 hingga 2019, full text article dengan berbahasa Inggris. Kata kunci yang digunakan adalah “”Health-Related Quality of Life”, “AND”, “Stable”, “AND”, “COPD”. Hasil: Systematic review ini menggunakan 14 artikel dengan 8401 responden. Kuesioner yang digunakan dalam studi adalah COPD Assasment Test (CAT). Tanda gejala dan eksaserbasi, kapasitas latihan fungsional, psikologi, sosiodemografi, biomolekul, komorbiditas dan faal paru mempengaruhi kualitas hidup pasien PPOK stabil. Kesimpulan: Banyak faktor yang mungkin memiliki hubungan dengan kualitas hidup pasien buruk karena kondisi penyakit PPOK itu sendiri yang kemudian berdampak pada seluruh tubuh. Saran: Petugas kesehatan perlu menyadari dan mengontrol kompleksnya dari faktor-faktor yang mempengaruhi kualitas hidup pasien PPOK sehingga menjadi membaik. Kata kunci: kualitas hidup; penyakit paru obstruktif kronik


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