scholarly journals Granulomatosis with Polyangiitis Localized in the Greater Omentum

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Ryuji Komine ◽  
Takashi Kobayashi ◽  
Hiro Uehara ◽  
Keisuke Minamimura ◽  
Kazuhiko Mori ◽  
...  

Granulomatosis with polyangiitis (GPA) is known as anti-neutrophil cytoplasmic antibody- (ANCA-) associated small vessel vasculitis and typically manifests as pulmonary-renal syndrome, but the disease is not limited to pulmonary or renal systems. The inflammation can involve whole body organs. In addition, the ANCA titer does not always become positive. Here, we describe the case of a 91-year-old man who presented with umbilical pain and fever of unknown origin. Only the increased computed tomography value of the greater omentum suggested intra-abdominal inflammation; however, serological examinations, including the ANCA level, could not reveal the focus or cause of symptoms. Finally, the histopathological examination of specimens surgically excised from the greater omentum demonstrated GPA limited to the greater omentum. This report reminds physicians to consider GPA in the differential diagnosis of acute abdominal pain or fever of unknown origin.

Nephron ◽  
2002 ◽  
Vol 92 (3) ◽  
pp. 673-675 ◽  
Author(s):  
Harun Akar ◽  
Cigdem Ozbaslı-Levi ◽  
Taskın Senturk ◽  
Gurhan Kadıkoylu ◽  
Edi Levi ◽  
...  

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Ramawad Soobrah ◽  
Mohammad Badran ◽  
Simon G. Smith

Segmental omental infarction (SOI) is a rare cause of acute abdominal pain. Depending on the site of infarction, it mimics conditions like appendicitis, cholecystitis, and diverticulitis. Before the widespread use of Computed Tomography (CT), the diagnosis was usually made intraoperatively. SOI produces characteristic radiological appearances on CT scan; hence, correct diagnosis using this form of imaging may prevent unnecessary surgery. We present the case of a young woman who was treated conservatively after accurate radiological diagnosis.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Anoshirwan Andrej Tavakoli ◽  
Miriam Reichert ◽  
Tanja Blank ◽  
Dietmar Dinter ◽  
Sabine Weckbach ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-15 ◽  
Author(s):  
Thomas Ebenhan ◽  
Olivier Gheysens ◽  
Hendrick Gert Kruger ◽  
Jan Rijn Zeevaart ◽  
Mike Machaba Sathekge

Antimicrobial peptides (AMPs) are a heterogeneous class of compounds found in a variety of organisms including humans and, so far, hundreds of these structures have been isolated and characterised. They can be described as natural microbicide, selectively cytotoxic to bacteria, whilst showing minimal cytotoxicity towards the mammalian cells of the host organism. They act by their relatively strong electrostatic attraction to the negatively charged bacterial cells and a relatively weak interaction to the eukaryote host cells. The ability of these peptides to accumulate at sites of infection combined with the minimal host’s cytotoxicity motivated for this review to highlight the role and the usefulness of AMPs for PET with emphasis on their mechanism of action and the different interactions with the bacterial cell. These details are key information for their selective properties. We also describe the strategy, design, and utilization of these peptides as potential radiopharmaceuticals as their combination with nuclear medicine modalities such as SPECT or PET would allow noninvasive whole-body examination for detection of occult infection causing, for example, fever of unknown origin.


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