scholarly journals Contrast-Induced Nephropathy: Update on the Use of Crystalloids and Pharmacological Measures

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
D. Patschan ◽  
I. Buschmann ◽  
O. Ritter
Keyword(s):  
Contrast Media ◽  
Clinical Studies ◽  
Preventive Measures ◽  
Severe Complication ◽  
Iodinated Contrast Media ◽  
Preventive Strategies ◽  
Contrast Induced Nephropathy ◽  
The Past ◽  
Iodinated Contrast ◽  
Meta Analyses

Contrast-induced nephropathy (CIN) is a frequent and severe complication in subjects receiving iodinated contrast media for diagnostic or therapeutic purposes. Several preventive strategies were evaluated in the past. Recent clinical studies and meta-analyses delivered some new aspects on preventive measures used in the past and present. We will discuss all pharmacological and nonpharmacological procedures. Finally, we will suggest individualized recommendations for CIN prevention.

High-Osmolar and Low-Osmolar Contrast Media

1993 ◽  
Vol 34 (3) ◽  
pp. 205-209 ◽  
Author(s):  
H. S. Thomsen ◽  
S. Dorph
Keyword(s):  
Contrast Media ◽  
Observational Studies ◽  
Randomized Trials ◽  
Iodinated Contrast Media ◽  
Intravascular Injection ◽  
Small Minority ◽  
The Past ◽  
Iodinated Contrast ◽  
Meta Analyses ◽  
Better Than

During the past 3 years a great number of papers about adverse drug reactions to intravascular injection of high-osmolar and low-osmolar iodinated contrast media (CM) have been published. They include observational studies, randomized trials, meta-analyses and committee reports. Thorough analysis of this material substantiates an improvement in safety of at least 6-fold using nonionic low-osmolar CM compared with ionic high-osmolar CM. The point where only a small minority is continuing to argue effectively that low-osmolar CM are not better than conventional high-osmolar CM has now been reached. High-osmolar CM are used less and less for intravascular purposes, and, in fact, have been totally replaced by low-osmolar CM in 4 countries.

Iodinated Contrast Media – A Safety Review

2009 ◽  
Vol 4 (1) ◽  
pp. 22 ◽  
Author(s):  
Raman Dusaj ◽  
Jonathan S Reiner ◽  
◽  
Keyword(s):  
Contrast Media ◽  
Clinical Studies ◽  
Patient Population ◽  
First Generation ◽  
Iodinated Contrast Media ◽  
Cardiac Events ◽  
Iodinated Contrast ◽  
Adverse Cardiac Events ◽  
The One ◽  
Meta Analyses

Iodinated contrast media (CM) are administered to millions of patients every year, yet controversy continues to exist regarding the safety of the various agents. Iodinated CM are either ionic or non-ionic, and vary in their osmolality relative to plasma. It is generally accepted that first-generation ionic, high-osmolality CM (HOCM) are less well tolerated than non-ionic, low-osmolar CM (LOCM). However, whether there are differences in safety among the remaining classes or individual CM, particularly with regard to nephrotoxicity and ischaemic complications, remains controversial. Many clinical studies and meta-analyses have compared the safety of the various CM and, depending on the patient population and study design, conflicting results have often been obtained. However, strong trends are emerging to indicate that, with regard to nephrotoxicity and adverse cardiac events, little if any differences exist among the majority of LOCM and between LOCM and the one available iso-osmolar contrast medium (IOCM). Herein we review the data regarding the tolerability, nephrotoxicity and thrombotic risks associated with the use of iodinated CM.

scholarly journals The molecular mechanism of contrast-induced nephropathy (CIN) and its link to in vitro studies on iodinated contrast media (CM)

BioMedicine ◽  
2018 ◽  
Vol 8 (1) ◽  
pp. 1 ◽  
Author(s):  
Jai-Sing Yang ◽  
Yan-Ru Peng ◽  
Shih-Chang Tsai ◽  
Yeu-Sheng Tyan ◽  
Chi-Cheng Lu ◽  
...  
Keyword(s):  
Contrast Media ◽  
Molecular Mechanism ◽  
In Vitro Studies ◽  
Iodinated Contrast Media ◽  
Contrast Induced Nephropathy ◽  
Iodinated Contrast

Protocol to prevent contrast‐induced nephropathy in parenteral challenge tests for allergy evaluation of hypersensitivity reactions to iodinated contrast media

2020 ◽  
Vol 50 (10) ◽  
pp. 1200-1203
Author(s):  
Francisco Vega ◽  
Maria Victoria Múgica ◽  
Laura Argíz ◽  
Raphaëlle Bazire ◽  
Maria Teresa Belver ◽  
...  
Keyword(s):  
Contrast Media ◽  
Hypersensitivity Reactions ◽  
Iodinated Contrast Media ◽  
Contrast Induced Nephropathy ◽  
Iodinated Contrast ◽  
Challenge Tests
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