scholarly journals Pulmonary Function Tests in Hypertensive Patients Attending Zewditu Memorial Hospital, Addis Ababa, Ethiopia

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Mekuriaw Mesfin Birhan ◽  
Yekoye Abebe

Background. Hypertension imposes stresses on many organs like heart and kidney. However, studies that show the effect of hypertension on the lungs are limited. Objective. To assess pulmonary function status of hypertensive patients aged 30-64 years at Zewditu Memorial Hospital, 2017. Methods. Hospital based comparative cross-sectional study was conducted on 61 hypertensive patients (cases) and 61 nonhypertensive clients (controls) aged 30-64 years. Computerized spirometry was done in all cases and controls which were selected by systematic sampling technique. The study was conducted from January 20, 2017, to May 25, 2017. Result. The values of FVC, FEV1, and FEF25-75% were 3.52±1.02 liters, 2.97±0.89 liters, and 3.34±1.3 liters/second in hypertensive patients and 4.31±0.82 liters, 3.54±0.7 liters, and 3.94±1.09 liters/second in controls, respectively. These values were significantly lower (p<0.05) in hypertensive patients compared to controls. Restrictive pulmonary defect was dominant in hypertensive patients. FEV1% which was 85%±7% in hypertensive patients and 82%±5% in controls was significantly higher (p<0.05) in hypertensive patients compared to controls. Conclusion. Hypertensive patients exhibit lower pulmonary function values. Routine check-up of the pulmonary function status of such patients should be done to prevent undesired outcomes.

2020 ◽  
Vol 10 (1) ◽  
pp. 36-41
Author(s):  
Divya Rayamajhi ◽  
Shreejana Wagle ◽  
Arun Karki

Introduction: Mental health and physical health are association with each other’s: poor mental health is a risk factor for chronic physical condition and it significantly impact on people’s quality of life. The social determinants of health impact on both chronic physical condition and mental health. The purpose of this study was to determine the prevalence sub-clinical depression and factors associated with depression among the hypertensive out patients’ department ofhospitals in Pokhara.  Methods: A hospital based cross-sectional study design was conducted among 215 hypertensive patient visiting OPD ward of selected hospitals of Pokhara Metropolitan City. Depression levels were assessed using the Beck Depression Inventory-Ia (BDI) scale. Demographics and risk factors were assessed. Systematic random sampling was conducted for selecting hospitals and proportionate random sampling technique was used to make the sample representative of hospitals. Results: Out of the total 215 hypertensive patients and around fifty-nine percentage were males and the mean age of respondents is 52 +12.04 years. Around one-third of the hypertensive patients had depression. The mean BDI-Ia score for depression status having respondent was 16.88±16.45. Conclusions: This study provides the evidence of depression is associate with hypertensive patient’s socio-demographic factors such as sex, age, marital status, employment and income and behavioral factors. Hypertensive patients should be encouraged to increase their physical activities and family support.


Neurology ◽  
2021 ◽  
pp. 10.1212/WNL.0000000000011458
Author(s):  
Kimberly Amburgey ◽  
Meryl Acker ◽  
Samia Saeed ◽  
Reshma Amin ◽  
Alan H. Beggs ◽  
...  

Objective:Nemaline myopathy (NM) is a rare neuromuscular condition with clinical and genetic heterogeneity. To establish disease natural history, we performed a cross-sectional study of NM, complemented by longitudinal assessment and exploration of pilot outcome measures.Methods:Fifty-seven individuals with NM were recruited at two family workshops, including 16 examined at both time points. Subjects were evaluated by clinical history and physical examination. Functional outcome measures included the Motor Function Measure (MFM), pulmonary function tests (PFTs), myometry, goniometry, and bulbar assessments.Results:The most common clinical classification was “typical congenital” (54%), whereas 42% had more severe presentations. 58% of individuals needed mechanical support, with 26% requiring wheelchair, tracheostomy, and feeding tube. The MFM scale was performed in 44/57 participants and showed reduced scores in most with little floor/ceiling effect. Of the 27 individuals completing PFTs, abnormal values were observed in 65%. Lastly, bulbar function was abnormal in all patients examined, as determined using a novel outcome measure. Genotypes included mutations in ACTA1 (18), NEB (20), and TPM2 (2). Seventeen individuals were genetically unresolved. Patients with pathogenic ACTA1 and NEB variants were largely similar in clinical phenotype. Patients without genetic resolution had more severe disease.Conclusion:In all, we present a comprehensive cross-sectional study of NM. Our data identify significant disabilities and support a relatively stable disease course. We identify a need for further diagnostic investigation for the genetically unresolved group. Lastly, MFM, pulmonary function tests, and the slurp test were identified as promising outcome measures for future clinical trials.


2019 ◽  
Author(s):  
Adey Girmay ◽  
Zelalem Tilahun ◽  
Muluemebet Zinabu Akele ◽  
solomon Assefa Huluka

Abstract Objective : Patients are essential sources of information to assess the accessibility and effectiveness of pharmaceutical care. Patients’ perception and satisfaction on the care they received has direct influence on treatment adherence. This study was thus aimed to assess HIV/AIDS patients’ level of satisfaction on the pharmaceutical services provided in Zewditu Memorial Hospital, Addis Ababa, Ethiopia. An institution based cross sectional study was conducted from April 16, 2018 to May 16, 2018 in Zewditu Memorial Hospital. Result: Among the total 285 participants enrolled in the study, 172(60.4%) of them were females and the mean age of the participants was 42.5±9.8. The participants of this study received ART service for a mean duration of 7.3±3.5 years. In this study, 26.7%, 13.7%, 38.6%, 13% and 8.1% of the study participants rated the overall satisfaction to the ART pharmaceutical service as excellent, very good, good, fair, and poor, respectively. Participants who were provided information about drug-drug and drug-food interaction were 2.72 times more likely to be satisfied than those who weren’t provided (AOR=2.72, 95%CI : 1.13-6.54).


2021 ◽  
Author(s):  
Bezina Damtew ◽  
Yoseph Tsige ◽  
Ketema Bizuwork ◽  
Sosina Workineh

Abstract Background cardiovascular related disorders are a major public health challenge in globally as well as in Ethiopia. It is crucial to improve the life style of the community at the same time it is a key for health care policy to give emphasis for prevention by educating the community by different ways. Therefore, the current study patient’s knowledge about risk factors related to those diseases. Method A facility-based descriptive cross-sectional study design was conducted. 420 Participants selected by systematic random sampling technique from April 01, 2021 until Jun 28, 2021 and met the criteria were included. Data was collected by interviewer-administered questionnaire. Level of knowledge was assessed by the Heart Disease Fact Questions. Bivariate and multivariate logistic regression was done to identify factors associated with identified class of knowledge. P-value less than 0.05 was considered as to indicate statistical significances. Result The result showed that most of the study subjects were in the age range of >54. The mean age was 48.7 ± 13 years. 255(62.7%) were females. 300(71.6%) of participants have sufficient knowledge toward cardiovascular diseases risk factors. Age, Sex, Place of residence, Status of education and Marital status was significantly associated with Participant’s knowledge (p<0.05, 95% C. I). Conclusion The majority of participants had sufficient knowledge regarding cardiovascular diseases risk factors. Maintaining good status, implementation of innovative interventions and structured, nurse-led lifestyle counseling would be required to effectively guide patients.


2021 ◽  
Author(s):  
MULUALEM ALEMAYEHU ◽  
Sintayehu Abebe ◽  
Dejuma Yadeta ◽  
Bekele Alemayehu

Abstract Background: Hypertension is the most common cardiovascular problem globally with a particularly increasing burden in developing countries like Ethiopia. Ambulatory blood pressure (ABPM) is superior to office blood pressure (OBP) measurement for diagnosing, prognosticating and following treatment efficacy for hypertension. There is no available data on ABPM control pattern in Ethiopians. This study will determine the ABPM control patterns in Ethiopian hypertensive patients on treatment. Material and Methods: This was a cross sectional study in hypertensive patients at Tikur Anbessa Specialized Hospitals outpatient departments carried out during January to May 2021. ABPM values of 244 consecutively sampled patients were analyzed. All patients had their BP monitored over 24 h with a Tonoport V (GE CS V6 71), and the data was interpreted using GE CardiosoftTM ABPM software in accordance with European Society of hypertension guidelines. Ethical clearance was given by Addis Ababa University Institutional Review Board and the study was conducted in compliance to standard ethical guidelines.Results: The study involved 244 adult hypertensive patients; mean age of the patients was 59.4years and, 54% were females. 58.6% of patients had controlled OBP, while only 45.1% had controlled ABPM. The mean OBP was 137 (19)/81 (10) mmHg and mean 24-hr ABP was 137 (16)/81 (10) mmHg; mean daytime BP was 136/79 ± 17/11 mmHg; mean night‑time BP, 138/84 ± 16/11 mmHg. Mean ABPM values were not significantly different between men and women. Comparison of ABPM values with OBP revealed high prevalence of the white coat effect (32%) and masked uncontrolled hypertension (46%). Presence of comorbidities particularly diabetes predicted poor ABPM control.Conclusion: More than half of patients had uncontrolled BP as per ABPM criteria and significant discrepancy exists between ABPM and OBP in assessing adequacy of BP control. Guiding management decisions using ABPM can improve BP control rates.


PLoS ONE ◽  
2022 ◽  
Vol 17 (1) ◽  
pp. e0262300
Author(s):  
Mulugeta Molla ◽  
Woretaw Sisay ◽  
Yared Andargie ◽  
Belayneh Kefale ◽  
Pradeep Singh

Introduction By measuring patients’ satisfaction, providers can gain insight into several elements of health care services, including the effectiveness of their care and the level of empathy they exhibit. The aim of this study was to assess patient satisfaction with pharmaceutical services and associated factors in public hospitals located in Northwestern Ethiopia. Methods An institution-based quantitative cross-sectional study was used. The study was carried out in an outpatient pharmacy from January 1–June 30, 2021. Participants were selected by a systematic sampling technique. The IBM SPSS statistical package (version 23) was used to enter and analyze the collected data. The findings were presented using descriptive statistical methods. To find factors linked to satisfaction, binary logistic regression was used. Results The final analysis included a total of 401 samples. More than half of the participants (229, or 55.1%) were female. The overall mean score of satisfaction was 30.6 out of a maximum of 100 scores. By taking this mean score as a cut-off point, 204 (50.9%) of the study participants had satisfaction with the outpatient pharmacists’ service. Participants’ responses scored on the uncomfortable and inconvenient waiting areas [AOR = 0.31; 95%CI, (0.13, 0.49)] were found to be negatively associated with the level of patients’ satisfaction. Also, the unavailability of medications [AOR = 0.12; 95%CI, (0.02, 0.37)] was negatively associated with the respondent satisfaction. Uncomfortable and inconvenient private counseling areas [AOR = 1.37; 95%CI, (0.79, 4.42)] showed a negative association with their satisfaction. Conclusion Patients’ satisfaction levels with pharmacy service were found to be greater than 50%. The socio-demographic characteristics of patients have no association with their level of satisfaction, but their perception of uncomfortable private counseling areas and waiting areas was negatively associated with their satisfaction.


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