scholarly journals Atypical Presentation of Lemierre’s Syndrome Causing Septic Shock and Acute Respiratory Distress Syndrome

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Divyesh Reddy Nemakayala ◽  
Manoj P Rai ◽  
Shilpa Kavuturu ◽  
Supratik Rayamajhi
Keyword(s):  
Septic Shock ◽  
Young Female ◽  
Sudden Onset ◽  
Lemierre’S Syndrome ◽  
Oropharyngeal Infection ◽  
Threatening Condition ◽  
Life Threatening ◽  
Chest X Ray ◽  
Lemierre’S Disease ◽  
Lemierre's Syndrome

Lemierre’s disease is a rare but life-threatening condition characterized by an oropharyngeal infection complicating with thrombophlebitis of the internal jugular vein and disseminated abscesses. We are presenting a case of a young female who initially presented with fevers, chills, sore throat, and swollen neck later developed progressively worsening shortness of breath along with sudden onset pleuritic chest pain. She then developed progressively worsening acute hypoxic respiratory failure requiring intubation and mechanical ventilation. Interval chest X-ray showed worsening bilateral effusions. She also developed septic shock requiring pressors. Blood culture showed Fusobacterium, and antibiotics were changed accordingly following which there was a clinical improvement. The diagnosis of Lemierre’s syndrome was then established based on her presenting age and bilateral pulmonary empyema in the setting of septicemia with Fusobacterium.

scholarly journals Lemierre’s Syndrome: Case Presentation of a Rare and Possibly Life-Threatening Condition

Medicina ◽  
2021 ◽  
Vol 57 (10) ◽  
pp. 1102
Author(s):  
Lucian Giubelan ◽  
Livia Dragonu ◽  
Vlad Pădureanu ◽  
Alexandru Neacșu ◽  
Mirela Mănescu ◽  
...  
Keyword(s):  
Jugular Vein ◽  
Anaerobic Bacteria ◽  
Rare Condition ◽  
Fusobacterium Necrophorum ◽  
Lemierre’S Syndrome ◽  
Case Presentation ◽  
Oropharyngeal Infection ◽  
Threatening Condition ◽  
Life Threatening ◽  
Lemierre's Syndrome

Lemierre’s syndrome is, presently, a very rare condition, but a life-threatening one. The syndrome was first described in 1936 by Andre Lemierre and comprises an oropharyngeal infection (most commonly associated with anaerobic bacteria Fusobacterium necrophorum), internal jugular vein thrombophlebitis and, possibly, secondary septic metastasis (common sites are lungs or brain). We describe such a rare case diagnosed at our Infectious Diseases Department in September 2019.

A rare, but life-threatening sore throat: A case of Lemierre’s syndrome

2021 ◽  
Vol 20 (1) ◽  
pp. 78-82
Author(s):  
A McCleane ◽  
◽  
M Hunter ◽  
PC Johnston ◽  
M Trimble ◽  
...  
Keyword(s):  
Sore Throat ◽  
Fusobacterium Necrophorum ◽  
Lung Abscess ◽  
Lemierre’S Syndrome ◽  
Blood Tests ◽  
Threatening Condition ◽  
Life Threatening ◽  
Lemierre's Syndrome ◽  
Initial Blood ◽  
Electrolyte Abnormalities

We present the case of a previously healthy, immunocompetent male with Lemierre’s Syndrome. He presented with headache, sore throat and pyrexia. Initial blood tests revealed raised inflammatory markers and electrolyte abnormalities. Blood cultured Fusobacterium necrophorum. He developed respiratory distress and imaging confirmed lung abscess and empyema due to septic emboli. He required surgical drainage and a prolonged course of antibiotics. This case highlights the rare, but life-threatening condition of Lemierre’s Syndrome. We discuss the importance of prompt recognition and early antibiotic therapy.

scholarly journals Lemierre’s Syndrome Associated with Mechanical Ventilation and Profound Deafness

2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Lukas Birkner
Keyword(s):  
Mechanical Ventilation ◽  
Cochlear Implant ◽  
Jugular Vein ◽  
Lemierre’S Syndrome ◽  
Oropharyngeal Infection ◽  
Profound Deafness ◽  
Ventilation Support ◽  
Mechanical Ventilation Support ◽  
Life Threatening ◽  
Lemierre's Syndrome

Lemierre’s syndrome is a rare disorder that is characterized by anaerobic organisms inducing a thrombophlebitis of the internal jugular vein (IJV) following a course of oropharyngeal infection. It often occurs in young and healthy patients. Clinicians continuously misinterpret early symptoms until infection disseminates systematically and life-threatening sepsis transpires. We report the case of a 58-year-old female developing Lemierre’s syndrome accompanied by invasive ventilation support and a profound deafness requiring the implementation of a cochlear implant. This is one of two reported cases of Lemierre’s syndrome associated with mechanical ventilation support and the only case associated with a cochlear implant.

scholarly journals Lemierre’s disease: a typical presentation in two diabetic patients

2020 ◽  
Vol 6 (12) ◽  
pp. 2279
Author(s):  
Bushra Hamdan Al Kalbani ◽  
Amar Singh ◽  
Salma Mohd Al Sheibani
Keyword(s):  
Jugular Vein ◽  
Klebsiella Pneumonia ◽  
Diabetic Patients ◽  
Haemophilus Influenza ◽  
Septic Emboli ◽  
Oropharyngeal Infection ◽  
Threatening Condition ◽  
Life Threatening ◽  
Lemierre’S Disease ◽  
Atypical Presentations

<p>Lemierre disease (LD) is a rare but potentially life-threatening condition, characterized internal jugular vein suppurative thrombophlebitis and disseminated septic emboli following a recent oropharyngeal infection. It is seen commonly in healthy young adolescents or adults, caused by gram negative anerobic <em>Fusoform necropharum</em>. Lack of awareness of this condition delays treatment and worsens prognosis. We present two interesting cases of LD in diabetic patients, caused by <em>Klebsiella pneumonia</em> and <em>Haemophilus influenza</em> organisms at our hospital. Both patients had atypical presentations. Diagnosis of such atypical cases poses diagnostic and therapeutic challenges.</p>

scholarly journals Fusobacterium necrophorumsepsis after tonsillitis/pharyngitis

2019 ◽  
Vol 12 (1) ◽  
pp. e222287 ◽  
Author(s):  
Micheal Sheehan ◽  
Darren McLoughlin ◽  
Ronan O’Sullivan
Keyword(s):  
Early Recognition ◽  
Rare Condition ◽  
Fusobacterium Necrophorum ◽  
Adverse Outcomes ◽  
Lemierre’S Syndrome ◽  
Metastatic Focus ◽  
Oropharyngeal Infection ◽  
History Of ◽  
Lemierre’S Disease ◽  
Lemierre's Syndrome

Fusobacterium necrophorumis a rare infection most notable for causing Lemierre’s syndrome. This consists of a primary oropharyngeal infection and septic thrombophlebitis, and one or more metastatic focus. Prior to the widespread use of antibiotics, Lemierre’s syndrome commonly followed a rapidly progressing course, with a high mortality. We describe a case of a previously well 18-month-old boy who presented to the emergency department with a 3-week history of progressive, right-sided, painful neck swelling and systemic sepsis. He was initially treated conservatively with intravenous antibiotics, but ultimately required surgical drainage. Lemierre’s syndrome is a rare condition with increasing incidence which can have significant adverse outcomes including death. Early recognition and treatment are essential, but identifying Lemierre’s disease is challenging.

scholarly journals Lemierre’s Syndrome: Rare, but Life Threatening—A Case Report withStreptococcus intermedius

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Shalini Gupta ◽  
Shehzad S. Merchant
Keyword(s):  
Early Recognition ◽  
Diagnostic Delay ◽  
Fusobacterium Necrophorum ◽  
Antimicrobial Treatment ◽  
Lemierre’S Syndrome ◽  
Presenting Symptoms ◽  
Oropharyngeal Infection ◽  
Life Threatening ◽  
Lemierre's Syndrome ◽  
Early Phases

Lemierre’s syndrome (LS) is a rare, but a life-threatening complication of an oropharyngeal infection. Combinations of fever, pharyngitis, dysphagia, odynophagia, or oropharyngeal swelling are common presenting symptoms. Infection of the lateral pharyngeal space may result in thrombosis of the internal jugular vein, subsequent metastatic complications (e.g., lung abscesses, septic arthritis), and significant morbidity and mortality. LS is usually caused by the gram-negative anaerobic bacillusFusobacterium necrophorum, hence also known as necrobacillosis. We present a case of LS caused byStreptococcus intermedius, likely secondary to gingival scraping, in which the presenting complaint was neck pain. The oropharyngeal examination was normal and an initial CT of the neck was done without contrast, which likely resulted in a diagnostic delay. This syndrome can be easily missed in early phases. However, given the potential severity of LS, early recognition and expedient appropriate antimicrobial treatment are critical.S. intermediusis an unusual cause of LS, with only 2 previous cases being reported in the literature. Therefore, an awareness of the myriad presentations of this syndrome, which in turn will lead to appropriate and timely diagnostic studies, will result in improved outcome for LS.

Lemierre's – the sinister sore throat

2007 ◽  
Vol 121 (7) ◽  
pp. 692-694 ◽  
Author(s):  
L M Brown ◽  
B Wallwork
Keyword(s):  
Temporal Lobe ◽  
Clinical Presentation ◽  
Sinus Thrombosis ◽  
Young Male ◽  
Lemierre’S Syndrome ◽  
Venous Infarction ◽  
Threatening Condition ◽  
Life Threatening ◽  
Lemierre's Syndrome ◽  
Management Issues

Lemierre's syndrome is a rare and sometimes life threatening condition that requires prompt management. A case is reported of a previously healthy young male with Lemierre's syndrome. He developed internal jugular vein and cavernous sinus thrombosis, metastatic abscesses in the temporal lobe and lungs, temporal lobe venous infarction and severe thrombocytopaenia. Discussed are aspects of clinical presentation, diagnosis and management issues.

scholarly journals A dangerous pleural effusion

2010 ◽  
Vol 92 (5) ◽  
pp. e53-e54 ◽  
Author(s):  
Somprakas Basu ◽  
Shilpi Bhadani ◽  
Vijay K Shukla
Keyword(s):  
Rare Complication ◽  
Sudden Onset ◽  
Biliary Surgery ◽  
Biliary Leak ◽  
X Ray ◽  
Delay In Diagnosis ◽  
Aged Woman ◽  
Middle Aged Woman ◽  
Life Threatening ◽  
Chest X Ray

Bilothorax is a rare complication of biliary peritonitis and, if not treated promptly, can be life-threatening. We report a case of a middle-aged woman who had undergone a bilio-enteric bypass and subsequently a biliary leak developed, which finally led to intra-abdominal biliary collection and spontaneous bilothorax. The clinical course was rapid and mimicked venous thromboembolism, myocardial infarction and pulmonary oedema, which led to a delay in diagnosis and management and finally death. We high-light the fact that bilothorax, although a rare complication of biliary surgery, should always be considered as a probable cause of massive effusion and sudden-onset respiratory and cardiovascular collapse in the postoperative period. A chest X-ray and a diagnostic pleural tap can confirm the diagnosis. Once detected, an aggressive management should be instituted to prevent organ failure and death.

Lemierre’s Syndrome: Are We Underdiagnosing This Life-Threatening Infection?

ORL ◽  
1996 ◽  
Vol 58 (3) ◽  
pp. 178-181 ◽  
Author(s):  
R.P.S. Harar ◽  
A. MacDonald ◽  
D. Pullen ◽  
S. Ganesan ◽  
A.J. Prior
Keyword(s):  
Lemierre’S Syndrome ◽  
Life Threatening ◽  
Lemierre's Syndrome
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