scholarly journals The Relationship between Colonization by Moraxella catarrhalis and Tonsillar Hypertrophy

2018 ◽  
Vol 2018 ◽  
pp. 1-9
Author(s):  
Mirela C. M. Prates ◽  
Edwin Tamashiro ◽  
José L. Proenca-Modena ◽  
Miriã F. Criado ◽  
Tamara H. Saturno ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Moraxella Catarrhalis ◽  
Pathogenic Bacteria ◽  
Simultaneous Detection ◽  
Tonsillar Hypertrophy ◽  
Palatine Tonsils ◽  
Adenotonsillar Hypertrophy

We sought to investigate the prevalence of potentially pathogenic bacteria in secretions and tonsillar tissues of children with chronic adenotonsillitis hypertrophy compared to controls. Prospective case-control study comparing patients between 2 and 12 years old who underwent adenotonsillectomy due to chronic adenotonsillar hypertrophy to children without disease. We compared detection of Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Pseudomonas aeruginosa, and Moraxella catarrhalis by real-time PCR in palatine tonsils, adenoids, and nasopharyngeal washes obtained from 37 children with and 14 without adenotonsillar hypertrophy. We found high frequency (>50%) of Haemophilus influenzae, Streptococcus pneumoniae, Moraxella catarrhalis, and Pseudomonas aeruginosa in both groups of patients. Although different sampling sites can be infected with more than one bacterium and some bacteria can be detected in different tissues in the same patient, adenoids, palatine tonsils, and nasopharyngeal washes were not uniformly infected by the same bacteria. Adenoids and palatine tonsils of patients with severe adenotonsillar hypertrophy had higher rates of bacterial coinfection. There was good correlation of detection of Moraxella catarrhalis in different sampling sites in patients with more severe tonsillar hypertrophy, suggesting that Moraxella catarrhalis may be associated with the development of more severe hypertrophy, that inflammatory conditions favor colonization by this agent. Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, and Moraxella catarrhalis are frequently detected in palatine tonsils, adenoids, and nasopharyngeal washes in children. Simultaneous detection of Moraxella catarrhalis in adenoids, palatine tonsils, and nasopharyngeal washes was correlated with more severe tonsillar hypertrophy.

scholarly journals Susceptibilidad a antimicrobianos de patógenos respiratorios en niños provenientes de la comunidad

2013 ◽  
Vol 65 (1) ◽  
pp. 14
Author(s):  
José M Guevara ◽  
Rosaluz Aróstegui ◽  
Wini Agurto ◽  
Iliana Sobrevilla ◽  
Esther Valencia ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Streptococcus Pyogenes ◽  
Moraxella Catarrhalis

OBJETIVO: Determinar la resistencia de los patógenos respiratorios a diferentes antimicrobianos. MATERIAL Y MÉTODOS: Entre abril y noviembre de 2002 se estudió 177 pacientes que asistieron al consultorio externo de otorrinolaringología del Hospital Nacional Docente Madre-Niño San Bartolomé. RESULTADOS: Streptococcus pneumoniae fue la bacteria patógena más aislada (57,2%), luego Moraxella catarrhalis (42,7%), Staphylococcus aureus (18,6%) y en pequeña cantidad Haemophilus influenzae (3,4%) y Streptococcus pyogenes (0,7%). Streptococcus pneumoniae presentó 31,3% de resistencia a la penicilina. El 96,7% de Moraxella catarrhalis fueron productoras de betalactamasa y 7,4% de los Staphylococcus aureus fueron resistentes a la oxacilina. CONCLUSIÓN: Streptococcus pneumoniae es el principal agente causal de los procesos infecciosos altos en niños y su resistencia a la penicilina aumentó a 31,3%

Một số đặc điểm kháng kháng sinh nhóm Beta-lactam của vi khuẩn tại Bệnh viện Đa khoa Quốc tế Hải Phòng, năm 2018 - 2020

2021 ◽  
Vol 31 (5) ◽  
pp. 25-31
Author(s):  
Nguyễn Thị Thu Phương ◽  
Trần Thị Ngân ◽  
Ngô Thị Quỳnh Mai
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Acinetobacter Baumannii ◽  
Beta Lactam

Nghiên cứu đã tiến hành phân tích kết quả xét nghiệm của 4722 mẫu bệnh phẩm vi sinh tại bệnh viện Đa khoa Quốc tế Hải Phòng từ năm 2018 đến năm 2020 nhằm mô tả một số đặc điểm kháng kháng sinh nhóm beta-lactam của một số vi khuẩn điển hình. Qua phân tích nhóm nghiên cứu thấy các vi khuẩn chủ yếu phân lập được là Escherichia coli (26,2%), Staphylococcus aureus (12,5%), và Haemophilus influenzae (8,6%). Vi khuẩn Escherichia coli kháng kháng sinh nhóm Beta-lactam với tỷ lệ khá cao (từ 1% (Imipenem) đến 29% (cefuroxime)). Tuy nhiên, vi khuẩn Streptococcus pneumoniae còn nhạy cảm với nhóm kháng sinh này với tỷ lệ kháng là 0%. Cefuroxime là kháng sinh có tỷ lệ bị kháng cao nhất với 42,7%. Các chủngvi khuẩn tại bệnh viện còn khá nhạy cảm với các kháng sinh thuộc nhóm carbapenem với tỷ lệ kháng thấp. Trong đó vi khuẩn là Acinetobacter baumannii và Pseudomonas aeruginosa có tỉ lệ kháng kháng sinh nhóm này từ 4,2% đến 5,2%. Kết quả nghiên cứu đã cung cấp dữ liệu về tính đề kháng kháng sinh betalactam của các vi khuẩn điển hình tại bệnh viện nhằm hỗ trợ các bác sĩ trong việc lựa chọn và sử dụng kháng sinh an toàn và hiệu quả

scholarly journals Moraxella Catarrhalis en las Infecciones Respiratorias Altas

2014 ◽  
Vol 58 (3) ◽  
pp. 192
Author(s):  
José Guevara Duncan ◽  
Jorge Navach ◽  
Rosaluz Aróstegui ◽  
Winni Agurto ◽  
Alfredo Goytendía ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Moraxella Catarrhalis ◽  
Haemophilus Influenza

Durante 12 meses se estudian las infecciones otorrinolaringológicas en dos hospitales de Lima, tanto en niños como en adultos, con especial énfasis en Moraxella catarrhalis. Se tomaron 318 muestras de igual número de pacientes, de los cuales el 40% resultó negativo a bacterias patógenas. Del 60% restante se identificó staphylococcus aureus como el causante del 31% de las infecciones, seguido de Streptococcus pneumoniae colt el 19%, hieto Moraxella catarrhalis colt 16% y en cuarto lugar Haemophilus influenzae colt 10%. Rinorrea purulenta fue el principal síntoma en todos los casos. Streptococcus pneumoniae, Moraxella catarrhalis y Haemophilus influenza se aislaron mayoritariamente en niños menores de 14 años. El 15% de los S. aureus fueron oxacilino-ressistentes, el 11% de S. pneumoniae fueron resistentes a la penicilina, el 70% de M. catarrhalis eran productoras de B-1actailiasay cl 5% de H. influenzae también producían lactamasa. Nuestros resultados permiten oriental-mayor el tratamiento antibiótico de las infecciones respiratorias altas.

scholarly journals Co-carriage of Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis among three different age categories of children in Hungary

PLoS ONE ◽  
2020 ◽  
Vol 15 (2) ◽  
pp. e0229021 ◽  
Author(s):  
Eszter Kovács ◽  
Judit Sahin-Tóth ◽  
Adrienn Tóthpál ◽  
Mark van der Linden ◽  
Tamás Tirczka ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Moraxella Catarrhalis

scholarly journals Increased recovery of Moraxella catarrhalis and Haemophilus influenzae in association with group A β-haemolytic streptococci in healthy children and those with pharyngo-tonsillitis

2006 ◽  
Vol 55 (8) ◽  
pp. 989-992 ◽  
Author(s):  
Itzhak Brook ◽  
Alan E. Gober
Keyword(s):  
Staphylococcus Aureus ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Moraxella Catarrhalis ◽  
Inflammatory Process ◽  
Bacterial Species ◽  
Healthy Children ◽  
Staph Aureus ◽  
Penicillin Therapy ◽  
Group A

The inflamed tonsils harbour numerous types of bacteria, alone or in combination with group A β-haemolytic streptococci (GABHS). The cohabitation of the tonsils by GABHS and certain other bacterial species may contribute to the inflammatory process and the failure of penicillin therapy. This study evaluated the recovery of Moraxella catarrhalis, Haemophilus influenzae, Staphylococcus aureus and Streptococcus pneumoniae in association with GABHS in healthy children and those with acute pharyngo-tonsillitis (APT). Pharyngo-tonsillar cultures were obtained from 548 children with APT and 866 healthy children. GABHS was recovered from 112 (20.4 %) children with APT. Of the 114 H. influenzae isolates, 32 were recovered in association with GABHS (29 % of all patients who had GABHS) and 82 were isolated without GABHS (19 %) (P=0.0267). Of the 69 M. catarrhalis isolates, 25 were recovered in association with GABHS (22 % of all patients who had GABHS) and 44 were isolated without GABHS (10 %) (P=0.0012). In contrast, there was no association between the isolation of GABHS and the recovery of Staph. aureus or Strep. pneumoniae. GABHS was recovered from 104 (12 %) healthy children. Of the 69 M. catarrhalis isolates, 24 were recovered in association with GABHS (23 % of all patients who had GABHS) and 80 were isolated without GABHS (10 %) (P=0.006). There was no association between the isolation of GABHS and the recovery of H. influenzae, Staph. aureus or Strep. pneumoniae. This study demonstrates an association between the recovery of GABHS and H. influenzae and M. catarrhalis from pharyngo-tonsillar cultures of patients with APT and M. catarrhalis from pharyngo-tonsillar cultures of healthy children.

scholarly journals PNEUMONIA BACTERIANA: ASPECTOS EPIDEMIOLÓGICOS, FISIOPATOLOGIA E AVANÇOS NO DIAGNÓSTICO

2018 ◽  
Vol 10 (1) ◽  
pp. 83 ◽  
Author(s):  
Raissa Guará Assunção ◽  
Wellison Amorim Pereira ◽  
Afonso Gomes Abreu
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Klebsiella Pneumonia ◽  
Acinetobacter Spp

A pneumonia é uma doença infecciosa que atinge os alvéolos pulmonares, ocasionada, principalmente, por bactérias, vírus, fungos e parasitas. Dentre as principais bactérias, Haemophilus influenzae, Klebsiella pneumonia, Streptococcus pneumoniae, Staphylococcus aureus e as do grupo das Gram-negativas não fermentadoras de glicose, a exemplo de Acinetobacter spp. e Pseudomonas aeruginosa, são as mais isoladas. Estima-se que 450 milhões de casos de pneumonia ocorram por ano em todo o mundo e o Brasil é protagonista na lista dos países com maior número de casos. Pacientes que fazem uso de ventilação mecânica têm até 21 vezes mais chances de desenvolver a doença e 20% daqueles que utilizam a técnica por mais de 48 horas desenvolverão a infecção. Desta forma, esta revisão teve por objetivo fazer uma avaliação crítica sistematizada da literatura sobre a doença, aspectos epidemiológicos, fisiopatologia e avanços no diagnóstico. Este estudo observou que houve uma evolução nos métodos de diagnóstico, resultando na diminuição expressiva do número de mortes. No entanto, para que a queda no número de acometidos se mantenha, a correta prescrição e utilização da antibioticoterapia são imprescindíveis.

scholarly journals Determination of antimicrobial action of "Apicold oral spray"

2021 ◽  
pp. 66-70
Author(s):  
Anatoly L. Kosakovsky ◽  
Oksana M. Golovnya ◽  
Svitlana G. Gunko ◽  
Ilona A. Kosakivska
Keyword(s):  
Staphylococcus Aureus ◽  
Candida Albicans ◽  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Streptococcus Pyogenes ◽  
Moraxella Catarrhalis ◽  
Antimicrobial Effect ◽  
Antimicrobial Action ◽  
Clinical Isolates ◽  
Fungicidal Action

Introduction: The causative agents of acute tonsillopharyngitis are viruses and bacterial flora. Treatment of acute pharyngitis is mainly local, which includes aerosols with antiseptics. Aim: Study of antimicrobial action of "Apicold oral spray" on clinical isolates of microorganisms Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, Moraxella catarrhalis and Candida albicans isolated from patients' oropharynx in patients. Material and methods: The effect of Apicold Oral Spray (manufactured by APIPHARMA doo) on clinical isolates of Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, Moraxella catarrhalis, and Candida albicans in Ukrainian patients was studied. Antimicrobial activity was assessed after 5, 10 and 20 minutes of action of one dose of "Apicold oral spray" on microorganisms. Bactericidal and fungicidal action (inhibition of cell growth of microorganisms) is expressed as a percentage according to the control. Results and discussion: Apicold Oral Spray has a 100% antimicrobial effect after 5 minutes on clinical isolates of Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, Moraxella catarrhalis and Candida albicans (complete growth inhibition of all 5 clinical isolates after 20 minutes). Conclusion: "Apicold oral spray" has a high antimicrobial effect on clinical isolates of Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, Moraxella catarrhalis and Candida albicans, which is confirmed by 100% inhibition of the growth of all bacteria after 5 minutes

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