scholarly journals Urachal Adenocarcinoma: A Case Report with Key Imaging Findings and Radiologic-Pathologic Correlation

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Willian Schmitt ◽  
Marta Baptista ◽  
Marco Ferreira ◽  
António Gomes ◽  
Ana Germano
Keyword(s):  
Weight Loss ◽  
Differential Diagnosis ◽  
Clinical History ◽  
Imaging Findings ◽  
Lesion Location ◽  
Patient Demographics ◽  
Pathologic Correlation ◽  
Associated Symptoms ◽  
History Of ◽  
Urachal Adenocarcinoma

Urachal pathologies are rare and can mimic numerous abdominal and pelvic diseases. Differential diagnosis of urachal anomalies can be narrowed down by proper assessment of lesion location, morphology, imaging findings, patient demographics, and clinical history. We report a case of a 60-year-old male, with a history of unintentional weight loss without associated symptoms, who was diagnosed with locally invasive urachal adenocarcinoma. With this article, we pretend to emphasize urachal adenocarcinoma clinical features along with its key imaging findings with radiologic-pathologic correlation.

Pneumatosis Coli in a Dog

2008 ◽  
Vol 44 (1) ◽  
pp. 32-35 ◽  
Author(s):  
Nicholas J. Russell ◽  
Dayle Tyrrell ◽  
Peter J. Irwin ◽  
Catherine Beck
Keyword(s):  
Weight Loss ◽  
Differential Diagnosis ◽  
Clinical Signs ◽  
Colorectal Disease ◽  
Abdominal Radiography ◽  
Pneumatosis Coli ◽  
History Of ◽  
Oral Metronidazole

A 17-year-old, castrated male Maltese was presented with chronic polyphagia and a 2-week history of tenesmus, diarrhea, hematochezia, weight loss, and ribbon-like feces. Pneumatosis coli was diagnosed by abdominal radiography. Concurrent hyperadrenocorticism was suspected. The clinical signs of colorectal disease resolved within 2 days of initiating a lowresidue diet and oral metronidazole. Pneumatosis coli should be considered as a differential diagnosis for colorectal disease in dogs.

scholarly journals Clinical history of HIV infection may be misleading in cytopathology

CytoJournal ◽  
2010 ◽  
Vol 7 ◽  
pp. 7 ◽  
Author(s):  
Liron Pantanowitz* ◽  
Michael Kuperman ◽  
Robert A. Goulart
Keyword(s):  
Differential Diagnosis ◽  
Hiv Infection ◽  
Primary Effusion Lymphoma ◽  
Clinical History ◽  
Hiv Status ◽  
Ct Guided ◽  
Increased Risk ◽  
Spindle Cell Proliferation ◽  
Atypical Cells ◽  
History Of

Human immunodeficiency virus (HIV)-infected patients are at an increased risk for developing opportunistic infections, reactive conditions and neoplasms. As a result, a broad range of conditions are frequently included in the differential diagnosis of HIV-related lesions. The clinical history of HIV infection may, however, be misleading in some cases. Illustrative cases are presented in which knowledge of a patient's HIV status proved to be misleading and increased the degree of complexity of the cytologic evaluation. Case 1 involved the fine needle aspiration (FNA) of a painful 3 cm unilateral neck mass in a 38-year-old female with generalized lymphadenopathy. Her aspirate revealed a spindle cell proliferation devoid of mycobacteria that was immunoreactive for S-100 and macrophage markers (KP-1, PGM1). Multiple noncontributory repeat procedures were performed until a final excision revealed a schwannoma. Case 2 was a CT-guided FNA of a positron emission tomography positive lung mass in a 53-year-old man. The acellular aspirate in this case contained structures resembling fungal spore forms that were negative for mucicarmine and GMS stains, as well as cryptococcal antigen immunocytochemistry. A Von Kossa stain confirmed that these pseudo-fungal structures were calcified debris. Follow up revealed multiple calcified lung and hilar node based granulomata. Case 3 involved the cytologic evaluation of pleural fluid from a 47-year-old man with Kaposi sarcoma and recurrent chylous pleural effusions. Large atypical cells identified in his effusion were concerning for primary effusion lymphoma. Subsequent pleural biopsy revealed extramedullary hematopoiesis, documenting these atypical cells as megakaryocytes. These cases demonstrate that knowledge of a patient's HIV status can be misleading in the evaluation of cytology specimens, with potential for misdiagnosis and/or multiple procedures. To avoid this pitfall in the setting of HIV infection, common entities unrelated to HIV infection and artifacts should always be included in the differential diagnosis.

Clear Cell Adenocarcinoma of the Cervix in a Child without in Utero Exposure to Diethylstilbestrol: A Case Report and Review of the Literature

2005 ◽  
Vol 8 (6) ◽  
pp. 690-695 ◽  
Author(s):  
William A. Ahrens ◽  
L. Patricia Barrón-Rodriguez ◽  
Millisa McKee ◽  
Scott Rivkees ◽  
Miguel Reyes-Múgica
Keyword(s):  
Differential Diagnosis ◽  
Clear Cell ◽  
Clinical History ◽  
In Utero ◽  
Embryonal Rhabdomyosarcoma ◽  
In Utero Exposure ◽  
Clear Cell Adenocarcinoma ◽  
Review Of The Literature ◽  
Cervical Tumor ◽  
History Of

We describe the case of a primary cervical tumor in a 6-year-old child that was originally suspected to be an embryonal rhabdomyosarcoma botryoides. Histologic analysis revealed a clear cell adenocarcinoma. Despite a direct search and questioning for maternal exposure to diethylstilbestrol, this was not documented. Clear cell adenocarcinoma is an extremely rare neoplasm that should be kept in the differential diagnosis of cervicovaginal lesions in children, even in the absence of a clinical history of in utero diethylstilbestrol exposure. We discuss the hypothesized pathogenesis and review the literature on this unusual tumor.

scholarly journals Whipple’s Disease: A Rare Cause of Diarreha

2021 ◽  
Vol 6 (6) ◽  
Keyword(s):  
Weight Loss ◽  
Fecal Incontinence ◽  
Physical Examination ◽  
Obese Patient ◽  
Personal History ◽  
Whipple’S Disease ◽  
Whipple's Disease ◽  
Associated Symptoms ◽  
History Of

We describe the case of a 55-year-old man, with a personal history of dyslipidemia, hyperuricemia and obesity, on atorvastatin and allopurinol. He went to a Gastroenterology consultation due to diarrhea with several years of evolution, from 3 daily spills, worsening in the last weeks to 10-12 daily spills, of liquid feces, without blood, mucus or pus, accompanied by defecatory urgency and fecal incontinence. He denied other associated symptoms, such as nausea, vomiting, weight loss or fever. Physical examination showed an obese patient, colored and hydrated skin and mucosa, without palpable adenomegalies, abdomen without changes.

Het is niet altijd Covid-19!

2021 ◽  
Author(s):  
F. DE BIÈVRE ◽  
A. SNOECKX ◽  
V. MATHEEUSSEN ◽  
G. MOORKENS
Keyword(s):  
Pulmonary Embolism ◽  
Differential Diagnosis ◽  
Pulmonary Thromboembolism ◽  
Signs And Symptoms ◽  
Fat Embolism ◽  
Orthopaedic Trauma ◽  
Imaging Findings ◽  
Total Occlusion ◽  
History Of ◽  
Real Challenge

It is not always Covid-19! Nonthrombotic pulmonary embolism (NTPE) is defined as a partial or total occlusion of the pulmonary circulation. Different causal agents exist. The prevalence is much lower compared to pulmonary thromboembolism. Due to the low specificity of the signs and symptoms, NTPE tends to be underestimated. The diagnosis is a real challenge as there is no standardised diagnostic tool. The imaging findings are heterogeneous, but usually present as diffuse ground-glass abnormalities. In this article, the medical history of two different cases of fat embolism after an orthopaedic trauma is reported. The importance of a good differential diagnosis must be emphasized.

Cutaneous Rosai–Dorfman disease: a challenging diagnosis

2021 ◽  
Vol 14 (2) ◽  
pp. e239244
Author(s):  
Rita Sampaio ◽  
Leandro Silva ◽  
Goreti Catorze ◽  
Isabel Viana
Keyword(s):  
Weight Loss ◽  
Differential Diagnosis ◽  
Physical Examination ◽  
Plasma Cells ◽  
Oral Prednisolone ◽  
Inflammatory Cells ◽  
Rosai Dorfman Disease ◽  
History Of ◽  
Nodular Lesions ◽  
Proliferative Disease

Rosai–Dorfman disease is a rare benign histiocytic proliferative disease of unknown cause that, in exceptional cases, presents with lesions confined to the skin. Clinically variable types of lesions such as papules, nodules and plaques have been reported. We present a case of a 27-year-old woman with a 1-year history of erythematous papular and nodular lesions on the malar and right axillary regions, previously misdiagnosed as acne. She reported no fever, malaise or weight loss, while physical examination and laboratory workup were normal. Bacteriological and mycobacteriological cultures were negative. Histopathological findings showed dense infiltration of inflammatory cells involving the entire dermis, consisting of large macrophages with emperipolesis, S100 and CD68 positive, neutrophils, eosinophils, lymphocytes and plasma cells. The patient was treated with oral prednisolone without improvement. Dapsone was subsequently initiated with favourable clinical response. The present article aimed to emphasise the clinical and histological differential diagnosis and share the treatment experience.

scholarly journals Metastasis of Malignant Melanoma to Urinary Bladder: A Case Report and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Rashna Meunier ◽  
Gyan Pareek ◽  
Ali Amin
Keyword(s):  
Differential Diagnosis ◽  
Malignant Melanoma ◽  
Urinary Bladder ◽  
Clinical History ◽  
Metastatic Malignant Melanoma ◽  
Review Of The Literature ◽  
Bladder Mucosa ◽  
Immunohistochemical Examination ◽  
History Of ◽  
The Right

Aims. Metastatic malignant melanoma of the urinary bladder is a rare clinical entity, with only twenty-three published cases to date. We present a case of this rare entity, a thorough review of the literature, and differential diagnosis of melanoma in the bladder.Methods and Results. A 55-year-old woman with a history of malignant melanoma of the right thigh, excised eight years ago, presented with back pain, fatigue, and hematuria. She underwent computed tomography (CT) scan and was found to have metastases within the liver, spleen, lungs, and urinary bladder. She underwent cystoscopy and transurethral resection of three polypoid lesions. Histologic and immunohistochemical examination revealed metastatic malignant melanoma involving bladder mucosa.Conclusions. This case illustrates the importance of including malignant melanoma in the differential diagnosis of high grade neoplasms of bladder, especially in cases where the relevant clinical history is not available.

scholarly journals PRIMARY DIAPHYSEAL TUBERCULOUS OSTEOMYELITIS OF TIBIA

2014 ◽  
Vol 21 (06) ◽  
pp. 1282-1284
Author(s):  
Ghulam Mustafa Kaim Khan ◽  
Syed Mujahid Humail ◽  
Kamran Hafeez
Keyword(s):  
Weight Loss ◽  
Developing Countries ◽  
Differential Diagnosis ◽  
Osteolytic Lesion ◽  
Long Bone ◽  
Low Grade ◽  
X Rays ◽  
X Ray ◽  
Tuberculous Osteomyelitis ◽  
History Of

Diaphyseal tubercular osteomyelitis of long bone is extremely rare and few cases have been reported in literature. We are presenting a case of 17 years old girl presented with pain and swelling over lower half of leg for 7 months. There was often low grade fever but no history of weight loss or pulmonary symptoms. X-ray chest was normal. X-rays and MRI of involved leg were suggestive of osteomyelitis. Curettage and biopsy was done, report was suggestive of tuberculous osteomyelitis. As tuberculosis is still common in developing countries, for an osteolytic lesion in bone, tuberculous osteomyelitis should be considered in differential diagnosis.

scholarly journals Tubercular Osteomyelitis of Tibia: A Case Report

2019 ◽  
Vol 2 (1) ◽  
pp. 92-94
Author(s):  
Amin Kumar Shrestha ◽  
Suman Raja Shrestha ◽  
Gopesh Kumar Thakur ◽  
Arjun Prasad Dumre
Keyword(s):  
Weight Loss ◽  
Differential Diagnosis ◽  
Osteolytic Lesion ◽  
Extrapulmonary Tuberculosis ◽  
Long Bone ◽  
Low Grade ◽  
X Rays ◽  
X Ray ◽  
Tuberculous Osteomyelitis ◽  
History Of

Tubercular osteomyelitis of long bone is extremely rare and very few cases have been reported in literature. We are presenting a case of 43 years gentlemen presented with pain and swelling over lower half of leg for 5 months. There was associated pus discharging sinus and often low-grade fever but no history of weight loss or pulmonary symptoms. X-ray chest was normal. X-rays of involved leg was suggestive of osteomyelitis. Curettage and Biopsy was done, report was suggestive of tuberculous osteomyelitis. As tuberculosis is still common in developing countries like Nepal, for any osteolytic lesion in bone, tubercular osteomyelitis should always be considered in differential diagnosis. Keywords: extrapulmonary tuberculosis; osteolytic lesion in bone; tubercular osteomyelitis.

Multifocal Oligodendroglioma in Three Dogs

2011 ◽  
Vol 47 (5) ◽  
pp. e77-e85 ◽  
Author(s):  
Michael W. Koch ◽  
Melissa D. Sánchez ◽  
Sam Long
Keyword(s):  
Spinal Cord ◽  
Differential Diagnosis ◽  
Seizure Activity ◽  
Clinical History ◽  
Brain Lesions ◽  
Behavior Changes ◽  
Neurologic Examination ◽  
Imaging Findings ◽  
Histopathologic Evaluation ◽  
And Behavior

This report describes the clinical, histopathologic, and imaging findings of multifocal oligodendrogliomas from three canine patients. Clinical history varied but included seizure activity and behavior changes. Neurologic examination abnormalities included ataxia, proprioceptive deficits, cranial nerve deficits, and changes in mentation. MRI in one patient revealed multifocal brain lesions; however, the MRI was normal in another one of the patients. Histopathologic evaluation identified multifocal neoplastic infiltrates in all three patients involving the cerebral cortex, brainstem, and spinal cord, with leptomeningeal extension in two of the three patients. All three patients were euthanized due to progression of their neurologic condition and/or complications due to aspiration pneumonia. Oligodendrogliomas should be considered a differential diagnosis for patients with multifocal brain disease.

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