scholarly journals The First Case Report of West Nile Virus-Induced Acute Flaccid Quadriplegia in Canada

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Yahya Salim Yahya Al-Fifi ◽  
Kamran Kadkhoda ◽  
Mike Drebot ◽  
Beverly Wudel ◽  
E. J. Bow
Keyword(s):  
New York ◽  
New York City ◽  
Case Report ◽  
West Nile Virus ◽  
York City ◽  
Favorable Outcome ◽  
West Nile ◽  
Neuroinvasive Disease ◽  
First Case ◽  
High Incidence

The 1999 New York City outbreak of West Nile virus (WNV) was associated with a high incidence of West Nile virus neuroinvasive disease (WNVND) where the outcomes for these patients were very poor. We describe a case of West Nile virus neuroinvasive disease (WNVND) characterized by acute flaccid quadriplegia with a favorable outcome in Winnipeg, Manitoba, Canada.

scholarly journals Pesticide Spraying for West Nile Virus Control and Emergency Department Asthma Visits in New York City, 2000

2004 ◽  
Vol 112 (11) ◽  
pp. 1183-1187 ◽  
Author(s):  
Adam M. Karpati ◽  
Mary C. Perrin ◽  
Tom Matte ◽  
Jessica Leighton ◽  
Joel Schwartz ◽  
...  
Keyword(s):  
Emergency Department ◽  
New York ◽  
New York City ◽  
West Nile Virus ◽  
York City ◽  
West Nile ◽  
Virus Control

West Nile virus infection in blood donors in the New York City area during the 2010 seasonal epidemic

Transfusion ◽  
2012 ◽  
Vol 52 (12) ◽  
pp. 2664-2670 ◽  
Author(s):  
Richard O. Francis ◽  
Donna Strauss ◽  
Joan Dunn Williams ◽  
Shavonne Whaley ◽  
Beth H. Shaz
Keyword(s):  
New York ◽  
New York City ◽  
West Nile Virus ◽  
Virus Infection ◽  
York City ◽  
Blood Donors ◽  
West Nile Virus Infection ◽  
West Nile ◽  
City Area ◽  
Seasonal Epidemic

An outbreak of West Nile virus in a New York City captive wildlife population.

2002 ◽  
Vol 67 (1) ◽  
pp. 67-75 ◽  
Author(s):  
George V Ludwig ◽  
Julie A Hile ◽  
Joseph A Mangiafico ◽  
Tracy L Clippinger ◽  
Bonnie L Raphael ◽  
...  
Keyword(s):  
New York ◽  
New York City ◽  
West Nile Virus ◽  
York City ◽  
West Nile ◽  
Wildlife Population

Force of Infection and Variation in Outbreak Size in a Multi-Species Host-Pathogen System

2020 ◽  
pp. 69-82
Author(s):  
John M. Drake ◽  
Krisztian Magori ◽  
Kevin Knoblich ◽  
Sarah E. Bowden ◽  
Waheed I. Bajwa
Keyword(s):  
New York ◽  
New York City ◽  
West Nile Virus ◽  
York City ◽  
Sampling Error ◽  
Spatial Scales ◽  
Contributing Factors ◽  
West Nile ◽  
Force Of Infection ◽  
Host Pathogen

The size of annual outbreaks in seasonally forced host-pathogen systems is poorly understood. We studied contributing factors to the six-fold observed variation in the number of human cases of West Nile virus in New York City in the years 2000–2008. Sampling error and intrinsic noise (demographic stochasticity) explain roughly half of the observed variation. To investigate the remaining sources of variation, we estimated the monthly force of infection from data on the distribution and abundance of mosquitoes, virus prevalence, vector competence, and mammal biting rate at two spatial scales. At both scales, the West Nile virus force of infection was remarkably consistent from year to year. We propose that fine scale spatial heterogeneity is the key to understanding the epidemiology of West Nile virus in New York City.

scholarly journals Infectious cDNA Clone of the Epidemic West Nile Virus from New York City

2002 ◽  
Vol 76 (12) ◽  
pp. 5847-5856 ◽  
Author(s):  
Pei-Yong Shi ◽  
Mark Tilgner ◽  
Michael K. Lo ◽  
Kim A. Kent ◽  
Kristen A. Bernard
Keyword(s):  
New York ◽  
New York City ◽  
West Nile Virus ◽  
Cdna Clone ◽  
York City ◽  
Infectious Cdna Clone ◽  
Full Length ◽  
Progeny Virus ◽  
West Nile ◽  
Full Length Cdna

ABSTRACT We report the first full-length infectious clone of the current epidemic, lineage I, strain of West Nile virus (WNV). The full-length cDNA was constructed from reverse transcription-PCR products of viral RNA from an isolate collected during the year 2000 outbreak in New York City. It was cloned into plasmid pBR322 under the control of a T7 promoter and stably amplified in Escherichia coli HB101. RNA transcribed from the full-length cDNA clone was highly infectious upon transfection into BHK-21 cells, resulting in progeny virus with titers of 1 × 109 to 5 × 109 PFU/ml. The cDNA clone was engineered to contain three silent nucleotide changes to create a StyI site (C to A and A to G at nucleotides [nt] 8859 and 8862, respectively) and to knock out an EcoRI site (A to G at nt 8880). These genetic markers were retained in the recovered progeny virus. Deletion of the 3′-terminal 199 nt of the cDNA transcript abolished the infectivity of the RNA. The plaque morphology, in vitro growth characteristics in mammalian and insect cells, and virulence in adult mice were indistinguishable for the parental and recombinant viruses. The stable infectious cDNA clone of the epidemic lineage I strain will provide a valuable experimental system to study the pathogenesis and replication of WNV.

scholarly journals Exposure of Domestic Mammals to West Nile Virus during an Outbreak of Human Encephalitis, New York City, 1999

2001 ◽  
Vol 7 (4) ◽  
pp. 736-738 ◽  
Author(s):  
Nicholas Komar ◽  
Nicholas A. Panella ◽  
Edward Boyce
Keyword(s):  
New York ◽  
New York City ◽  
West Nile Virus ◽  
York City ◽  
West Nile
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