scholarly journals On the Global Dynamics of a Vector-Borne Disease Model with Age of Vaccination

2018 ◽  
Vol 2018 ◽  
pp. 1-11 ◽  
Author(s):  
Stanislas Ouaro ◽  
Ali Traoré
Keyword(s):  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Mass Action ◽  
Global Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Vector Borne Disease ◽  
Special Cases ◽  
Vector Borne ◽  
The Basic Reproduction Number

We study a vector-borne disease with age of vaccination. A nonlinear incidence rate including mass action and saturating incidence as special cases is considered. The global dynamics of the equilibria are investigated and we show that if the basic reproduction number is less than 1, then the disease-free equilibrium is globally asymptotically stable; that is, the disease dies out, while if the basic reproduction number is larger than 1, then the endemic equilibrium is globally asymptotically stable, which means that the disease persists in the population. Using the basic reproduction number, we derive a vaccination coverage rate that is required for disease control and elimination.

scholarly journals Global Dynamics of an SIQR Model with Vaccination and Elimination Hybrid Strategies

Mathematics ◽  
2018 ◽  
Vol 6 (12) ◽  
pp. 328 ◽  
Author(s):  
Yanli Ma ◽  
Jia-Bao Liu ◽  
Haixia Li
Keyword(s):  
Lyapunov Function ◽  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Endemic Equilibrium ◽  
Global Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Disease Free ◽  
The Basic Reproduction Number

In this paper, an SIQR (Susceptible, Infected, Quarantined, Recovered) epidemic model with vaccination, elimination, and quarantine hybrid strategies is proposed, and the dynamics of this model are analyzed by both theoretical and numerical means. Firstly, the basic reproduction number R 0 , which determines whether the disease is extinct or not, is derived. Secondly, by LaSalles invariance principle, it is proved that the disease-free equilibrium is globally asymptotically stable when R 0 < 1 , and the disease dies out. By Routh-Hurwitz criterion theory, we also prove that the disease-free equilibrium is unstable and the unique endemic equilibrium is locally asymptotically stable when R 0 > 1 . Thirdly, by constructing a suitable Lyapunov function, we obtain that the unique endemic equilibrium is globally asymptotically stable and the disease persists at this endemic equilibrium if it initially exists when R 0 > 1 . Finally, some numerical simulations are presented to illustrate the analysis results.

Global dynamics for a live-virus-blood model with distributed time delay

2017 ◽  
Vol 10 (05) ◽  
pp. 1750067 ◽  
Author(s):  
Ding-Yu Zou ◽  
Shi-Fei Wang ◽  
Xue-Zhi Li
Keyword(s):  
Steady State ◽  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Global Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Live Virus ◽  
Number Formula ◽  
Distributed Time Delay ◽  
The Basic Reproduction Number

In this paper, the global properties of a mathematical modeling of hepatitis C virus (HCV) with distributed time delays is studied. Lyapunov functionals are constructed to establish the global asymptotic stability of the uninfected and infected steady states. It is shown that if the basic reproduction number [Formula: see text] is less than unity, then the uninfected steady state is globally asymptotically stable. If the basic reproduction number [Formula: see text] is larger than unity, then the infected steady state is globally asymptotically stable.

scholarly journals Dynamics of a vector-borne model with direct transmission and age of infection.

2021 ◽  
Author(s):  
Necibe Tuncer ◽  
Sunil Giri
Keyword(s):  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Endemic Equilibrium ◽  
Asymptotically Stable ◽  
Direct Transmission ◽  
Globally Asymptotically Stable ◽  
Born Model ◽  
Age Of Infection ◽  
Vector Borne ◽  
The Basic Reproduction Number

In this paper we the study of dynamics of time since infection structured vector born model with the direct transmission. We use standard incidence term to model the new infections. We analyze the corresponding system of partial di erential equation and obtain an explicit formula for the basic reproduction number R0. The diseases-free equilibrium is locally and globally asymptotically stable whenever the basic reproduction number is less than one, R0 < 1. Endemic equilibrium exists and is locally asymptotically stable when R0 > 1. The disease will persist at the endemic equilibrium whenever the basic reproduction number is greater than one.

scholarly journals Global Stability of an Epidemic Model with Incomplete Treatment and Vaccination

2012 ◽  
Vol 2012 ◽  
pp. 1-14 ◽  
Author(s):  
Hai-Feng Huo ◽  
Li-Xiang Feng
Keyword(s):  
Global Stability ◽  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Global Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Incomplete Treatment ◽  
Disease Free ◽  
The Basic Reproduction Number

An epidemic model with incomplete treatment and vaccination for the newborns and susceptibles is constructed. We establish that the global dynamics are completely determined by the basic reproduction numberR0. IfR0≤1, then the disease-free equilibrium is globally asymptotically stable. IfR0>1, the endemic equilibrium is globally asymptotically stable. Some numerical simulations are also given to explain our conclusions.

scholarly journals Global Dynamics of a Discretized Heroin Epidemic Model with Time Delay

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Xamxinur Abdurahman ◽  
Ling Zhang ◽  
Zhidong Teng
Keyword(s):  
Time Delay ◽  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Global Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Nonstandard Finite Difference Scheme ◽  
Nonstandard Finite Difference ◽  
The Basic Reproduction Number

We derive a discretized heroin epidemic model with delay by applying a nonstandard finite difference scheme. We obtain positivity of the solution and existence of the unique endemic equilibrium. We show that heroin-using free equilibrium is globally asymptotically stable when the basic reproduction numberR0<1, and the heroin-using is permanent when the basic reproduction numberR0>1.

scholarly journals Global dynamics of a delayed epidemic model with latency and relapse

2013 ◽  
Vol 18 (2) ◽  
pp. 250-263 ◽  
Author(s):  
Rui Xu
Keyword(s):  
Basic Reproduction Number ◽  
Local Stability ◽  
Reproduction Number ◽  
Endemic Equilibrium ◽  
Global Dynamics ◽  
Lyapunov Functionals ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Disease Free ◽  
The Basic Reproduction Number

A mathematical model describing the transmission dynamics of an infectious disease with an exposed (latent) period, relapse and a saturation incidence rate is investigated. By analyzing the corresponding characteristic equations, the local stability of a disease-free equilibrium and an endemic equilibrium is established. By using suitable Lyapunov functionals and LaSalle’s invariance principle, it is proven that if the basic reproduction number is less than unity, the diseasefree equilibrium is globally asymptotically stable and therefore the disease fades out; and if the basic reproduction number is greater than unity, the endemic equilibrium is globally asymptotically stable and the disease becomes endemic.

GLOBAL DYNAMICS OF AN IN-HOST HIV-1 INFECTION MODEL WITH THE LONG-LIVED INFECTED CELLS AND FOUR INTRACELLULAR DELAYS

2012 ◽  
Vol 05 (06) ◽  
pp. 1250058 ◽  
Author(s):  
SHIFEI WANG ◽  
YICANG ZHOU
Keyword(s):  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Infection Model ◽  
Global Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Infected Cells ◽  
Hiv 1 ◽  
Intracellular Delays ◽  
The Basic Reproduction Number

In this paper, we investigate global dynamics for an in-host HIV-1 infection model with the long-lived infected cells and four intracellular delays. Our model admits two possible equilibria, an uninfected equilibrium and infected equilibrium depending on the basic reproduction number. We derive that the global dynamics are completely determined by the values of the basic reproduction number: if the basic reproduction number is less than one, the uninfected equilibrium is globally asymptotically stable, and the virus is cleared; if the basic reproduction number is larger than one, then the infection persists, and the infected equilibrium is globally asymptotically stable.

GLOBAL DYNAMICS OF AN SVIR EPIDEMIOLOGICAL MODEL WITH INFECTION AGE AND NONLINEAR INCIDENCE

2017 ◽  
Vol 25 (03) ◽  
pp. 419-440
Author(s):  
ZHIPING WANG ◽  
RUI XU
Keyword(s):  
Steady State ◽  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Epidemiological Model ◽  
Global Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Nonlinear Incidence ◽  
Infection Age ◽  
The Basic Reproduction Number

In this paper, an SVIR epidemiological model with infection age (time elapsed since the infection) and nonlinear incidence is studied. In the model, in order to reflect the dependence of disease progress on the infection age, the infected individual is structured by the infection age, and transmission and removal rates are assumed to depend on the infection age. By analyzing corresponding characteristic equations, the local stability of each of steady states of the model is established. It is proved that the semi-flow generated by this system is asymptotically smooth, and if the basic reproduction number is greater than unity, the system is uniformly persistent. By using Lyapunov functional and LaSalle’s invariance principle, the global dynamics of the model is investigated. It is shown that if the basic reproduction number is less than unity, the disease-free steady state is globally asymptotically stable and hence the disease dies out; and if the basic reproduction number is greater than unity, the endemic steady state is globally asymptotically stable and the disease persists. Numerical simulations are carried out to illustrate the main analytic results.

Global dynamics of two heterogeneous SIR models with nonlinear incidence and delays

2016 ◽  
Vol 09 (03) ◽  
pp. 1650046 ◽  
Author(s):  
Haitao Song ◽  
Weihua Jiang ◽  
Shengqiang Liu
Keyword(s):  
Incidence Rate ◽  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Global Dynamics ◽  
Group Model ◽  
Theoretic Approach ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Nonlinear Incidence ◽  
The Basic Reproduction Number

To investigate the effect of heterogeneity on the global dynamics of two SIR epidemic models with general nonlinear incidence rate and infection delays, we formulate a multi-group model corresponding to the heterogeneity in the host population and a multi-stage model corresponding to heterogeneous stages of infection. Under biologically motivated considerations, we establish that the global dynamics for each of the two models is determined completely by the corresponding basic reproduction number: if the basic reproduction number is less than or equal to one, then the disease-free equilibrium is globally asymptotically stable and the disease dies out in all groups or stages; if the basic reproduction number is larger than one, then the disease will persist in all groups or stages, and there is a unique endemic equilibrium which is globally asymptotically stable. Then we conclude that the heterogeneity does not change the global dynamics of the SIR model when the incidence rate is a general nonlinear function. Our results extend a class of previous results and can be applied to the other epidemiological models. The proofs of the main results use Lyapunov functional and graph-theoretic approach.

scholarly journals Threshold Dynamics of a Huanglongbing Model with Logistic Growth in Periodic Environments

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Jianping Wang ◽  
Shujing Gao ◽  
Yueli Luo ◽  
Dehui Xie
Keyword(s):  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Logistic Growth ◽  
Threshold Dynamics ◽  
Global Dynamics ◽  
Globally Asymptotically Stable ◽  
Linear Integral ◽  
The Impact ◽  
Disease Free ◽  
The Basic Reproduction Number

We analyze the impact of seasonal activity of psyllid on the dynamics of Huanglongbing (HLB) infection. A new model about HLB transmission with Logistic growth in psyllid insect vectors and periodic coefficients has been investigated. It is shown that the global dynamics are determined by the basic reproduction numberR0which is defined through the spectral radius of a linear integral operator. IfR0< 1, then the disease-free periodic solution is globally asymptotically stable and ifR0> 1, then the disease persists. Numerical values of parameters of the model are evaluated taken from the literatures. Furthermore, numerical simulations support our analytical conclusions and the sensitive analysis on the basic reproduction number to the changes of average and amplitude values of the recruitment function of citrus are shown. Finally, some useful comments on controlling the transmission of HLB are given.

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