scholarly journals Association between Physical Exercise and Biomarkers of Oxidative Stress among Middle-Aged and Elderly Community Residents with Essential Hypertension in China

2018 ◽  
Vol 2018 ◽  
pp. 1-11 ◽  
Author(s):  
Ying Yu ◽  
Qin Gao ◽  
Wanning Xia ◽  
Lina Zhang ◽  
Zhiyuan Hu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Essential Hypertension ◽  
Physical Exercise ◽  
Sod Activity ◽  
Community Residents ◽  
Stress Biomarker ◽  
Oxidative Stress Biomarker ◽  
Biomarkers Of Oxidative Stress

This study aimed to investigate the role of different types and frequencies of physical exercise in biomarkers of oxidative stress among middle-aged and elderly community residents with essential hypertension in China. A community-based cross-sectional survey was undertaken in 7 subdistricts. Individuals, 45-79 years old, with essential hypertension (n=402) and without cardiovascular disease (n=1047) were included. Superoxide dismutase (SOD) activities and plasma levels of malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) were determined. Multilevel linear regression was used to estimate the associations between various types of physical exercise and oxidative stress biomarker levels. Participants engaged in high frequency walking/square dancing or taiji/yoga demonstrated decreased systolic blood pressure in both groups; however, diastolic blood pressure decreased only among individuals with hypertension participating in walking/square dancing. In individuals with hypertension, MDA levels decreased in those participating in walking/square dancing, SOD activity increased in those participating in walking/square dancing, and 4-HNE levels decreased in those involved in taiji/yoga. In individuals without cardiovascular disease, MDA levels decreased in those involved in walking/square dancing or taiji/yoga, SOD activity increased in those performing walking/square dancing, and 4-HNE levels decreased in those involved in taiji/yoga. Oxidative stress marker levels also improved in those involved in walking/square dancing or taiji/yoga groups as the exercise frequency increased. Thus, frequent participation in walking/square dancing or taiji/yoga effectively decreases hypertension-related oxidative stress biomarker levels.

Monitoring of Urinary Oxidative Stress Biomarker Levels in Newborns with Hypoxic-Ischemic Encephalopathy

2020 ◽  
Vol 159 ◽  
pp. S115
Author(s):  
Mari Merce Cascant Vilaplana ◽  
Ángel Sánchez-Illana ◽  
José David Piñeiro-Ramos ◽  
Guillermo Quintás ◽  
Camille Oger ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Hypoxic Ischemic Encephalopathy ◽  
Ischemic Encephalopathy ◽  
Stress Biomarker ◽  
Oxidative Stress Biomarker

scholarly journals Oxidative Stress Biomarkers, Nut-Related Antioxidants, and Cardiovascular Disease

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 682 ◽  
Author(s):  
Julia Lorenzon dos Santos ◽  
Alexandre Schaan de Quadros ◽  
Camila Weschenfelder ◽  
Silvia Bueno Garofallo ◽  
Aline Marcadenti
Keyword(s):  
Oxidative Stress ◽  
Cardiovascular Disease ◽  
Cardiovascular Prevention ◽  
Food Sources ◽  
Dietary Antioxidants ◽  
Oxidative Stress Biomarkers ◽  
Atherosclerosis Progression ◽  
Coronary Syndrome ◽  
Biomarkers Of Oxidative Stress

Atherosclerosis is related to fat accumulation in the arterial walls and vascular stiffening, and results in acute coronary syndrome which is commonly associated with acute myocardial infarction. Oxidative stress participates in the pathogenesis of atherosclerosis. Thus, the inclusion of food sources of dietary antioxidants, such as different kinds of nuts, may improve biomarkers related to oxidative stress, contributing to a possible reduction in atherosclerosis progression. This article has briefly highlighted the interaction between oxidative stress, atherosclerosis, and cardiovascular disease, in addition to the effect of the consumption of different nuts and related dietary antioxidants—like polyphenols and vitamin E—on biomarkers of oxidative stress in primary and secondary cardiovascular prevention. Studies in vitro suggest that nuts may exert antioxidant effects by DNA repair mechanisms, lipid peroxidation prevention, modulation of the signaling pathways, and inhibition of the MAPK pathways through the suppression of NF-κB and activation of the Nrf2 pathways. Studies conducted in animal models showed the ability of dietary nuts in improving biomarkers of oxidative stress, such as oxLDL and GPx. However, clinical trials in humans have not been conclusive, especially with regards to the secondary prevention of cardiovascular disease.

Detection of Oxidative Stress Biomarker Homocysteine Utilizing Resonance Elastic Light Scattering

2019 ◽  
Vol 28 (18) ◽  
pp. 115-128
Author(s):  
Magdalena Stobiecka ◽  
Sara Cutler ◽  
Zachary Reed ◽  
Amanda Prance ◽  
Maria Hepel
Keyword(s):  
Oxidative Stress ◽  
Light Scattering ◽  
Elastic Light Scattering ◽  
Stress Biomarker ◽  
Oxidative Stress Biomarker

scholarly journals A Subpressor Dose of Angiotensin II Elevates Blood Pressure in a Normotensive Rat Model by Oxidative Stress

2015 ◽  
pp. 153-159 ◽  
Author(s):  
M. M. GOVENDER ◽  
A. NADAR
Keyword(s):  
Oxidative Stress ◽  
Blood Pressure ◽  
Angiotensin Ii ◽  
Mrna Expression ◽  
Rat Model ◽  
Wistar Rat ◽  
Control Group ◽  
Sod Activity ◽  
Male Wistar Rats ◽  
Experimental Group

Oxidative stress is an imbalance between free radicals and antioxidants, and is an important etiological factor in the development of hypertension. Recent experimental evidence suggests that subpressor doses of angiotensin II elevate oxidative stress and blood pressure. We aimed to investigate the oxidative stress related mechanism by which a subpressor dose of angiotensin II induces hypertension in a normotensive rat model. Normotensive male Wistar rats were infused with a subpressor dose of angiotensin II for 28 days. The control group was sham operated and infused with saline only. Plasma angiotensin II and H2O2 levels, whole-blood glutathione peroxidase, and AT-1a, Cu/Zn SOD, and p22phox mRNA expression in the aorta was assessed. Systolic and diastolic blood pressures were elevated in the experimental group. There was no change in angiotensin II levels, but a significant increase in AT-1a mRNA expression was found in the experimental group. mRNA expression of p22phox was increased significantly and Cu/Zn SOD decreased significantly in the experimental group. There was no significant change to the H2O2 and GPx levels. Angiotensin II manipulates the free radical-antioxidant balance in the vasculature by selectively increasing O2− production and decreasing SOD activity and causes an oxidative stress induced elevation in blood pressure in the Wistar rat.

scholarly journals The Extracellular Protein, Transthyretin Is an Oxidative Stress Biomarker

2019 ◽  
Vol 10 ◽  
Author(s):  
Meesha Sharma ◽  
Sheeza Khan ◽  
Safikur Rahman ◽  
Laishram Rajendrakumar Singh
Keyword(s):  
Oxidative Stress ◽  
Extracellular Protein ◽  
Stress Biomarker ◽  
Oxidative Stress Biomarker

Biosensor for the oxidative stress biomarker glutathione based on SAM of cobalt phthalocyanine on a thioctic acid modified gold electrode

2019 ◽  
Vol 23 (4) ◽  
pp. 1129-1144 ◽  
Author(s):  
Mohammed Nooredeen Abbas ◽  
Ayman Ali Saeed ◽  
Mounir Ben Ali ◽  
Abdelhamid Errachid ◽  
Nadia Zine ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Gold Electrode ◽  
Cobalt Phthalocyanine ◽  
Thioctic Acid ◽  
Stress Biomarker ◽  
Oxidative Stress Biomarker

scholarly journals Clinical disparity of oxidative stress with blood pressure

2019 ◽  
pp. 3
Author(s):  
Elsa Mathew ◽  
J.K. Mukkadan
Keyword(s):  
Oxidative Stress ◽  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Total Cholesterol ◽  
Diastolic Blood Pressure ◽  
Pearson Correlation ◽  
World Health ◽  
Oxidative Stress Marker ◽  
Major Public Health Problem ◽  
Hypertensive Patients

Background: Cardiovascular disease is one of the leading causes of mortality and morbidity in India and worldwide. Hypertension is a major public health problem because of its high frequency and concomitant risk of cardiovascular disease, kidney disease, and stroke. World Health Organization named it a Silent killer as hypertension is asymptomatic during its clinical course. Experimental evidence supports a role for oxidative stress in vascular injury and hypertension. This study was undertaken, to compare the serum levels of malondialdehyde (MDA) and super-oxide dismutase (SOD) among normotensive, prehypertensive and hypertensive subjects. Materials and methods: In this cross-sectional study, 34 normotensives, 44 prehypertensive and 45 hypertensive subjects were included. The participants were subjected to selection protocol consisting of physical examination and biochemical analysis. All subjects underwent blood pressure measurement, total cholesterol, and oxidative stress marker estimation, especially SOD and MDA. The comparison of parameters between the group was carried out using One Way ANOVA. The correlation between the parameter was analyzed by Karl Pearson Correlation Coefficient using SPSS 20.0. Result : The MDA (nmol/ml) in normotensive, prehypertensive and hypertensive patients was 2.55±0.072, 3.43±0.44 and 4.01±0.37 respectively. SOD (U/ml) level in normotensive, prehypertensive and hypertensive patients was 13.47±1.96, 11.57±0.81, and 8.52±1.78 respectively. Systolic and diastolic blood pressure had a negative correlation with SOD. MDA levels show a positive correlation with systolic blood pressure and diastolic blood pressure. Total cholesterol had no significant with SOD and MDA. Conclusion: The present study showed a strong association of oxidative stress with systolic and diastolic blood pressure.

scholarly journals Serum albumin cysteine trioxidation is a potential oxidative stress biomarker of type 2 diabetes mellitus

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Selvam Paramasivan ◽  
Sunil S. Adav ◽  
SoFong Cam Ngan ◽  
Rinkoo Dalan ◽  
Melvin Khee-Shing Leow ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Serum Albumin ◽  
Stress Biomarker ◽  
Oxidative Stress Biomarker
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