scholarly journals An Exceptional Adenocarcinoma in a Girl

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Bangaly Traore ◽  
Ibrahima Kalil Cisse ◽  
Malick Bah ◽  
Ahmed Monzomba Keita

Anal adenocarcinoma is very rare and usually occurs in the elderly. We present a case of a 12-year-old girl with an anal margin painful tumor infiltrating the lower rectum, with perineal and vulvar permeation nodules and bilateral fixed inguinal and iliac lymph nodes. Histology showed anal adenocarcinoma with mucosecreting component and independent cells. She had no extra pelvic metastasis on CT scan. She underwent a colostomy and palliative care. This exceptional case challenges us on the diversity of forms of anal cancers that require a multidisciplinary approach. The precarious social context and the age of onset make it difficult to manage this rare cancer.

2019 ◽  
Vol 29 (4) ◽  
Author(s):  
Elham Hesari ◽  
Zahra Sabzi ◽  
Shohreh Kolagari

Chronic pain is among problems of old people and causes changes in their life pattern and processes. Teaching palliative care can help old people suffering from chronic pain to live an active life. The aim of this research was to determine effects of educating of palliative care on life pattern of elderly women with chronic pain. The present study was a Quasi-experimental design with pre-test and post test was conducted on 30 elderly women suffering from chronic pain in 2018 in Iran. The Questionnaire for evaluating the Pattern of Life with Pain in the elderly was filled before the intervention, group educating of palliative care was carried out using an educational package, and the questionnaire was completed again immediately and one and three months after. The data was analyzed using mean, standard deviations, Fisher’s F test, and Greenhouse-Geisser and Bonferroni post-hoc test by employing SPSS- 16. Mean changes before teaching palliative care significantly differed from those of immediately and one and three months after the educational program (p = 0.0), (p = 0.004). There were significant differences between the stages of immediately and one month after the educational program and that of three months after it (p = 0.001), (p = 0.002). Concerning the personal life patterns, there were statistically significant differences between the stage immediately after the educational program and those before the intervention and three months after it (p = 0.005), (p = 0.000). Regarding the social life pattern, only the stage of one month after the educational program significantly differed from that of three months (p = 0.005). Mean growth in life pattern of the old women suffering from chronic pain in the stages after the intervention indicated the importance of and the necessity for palliative care during old age. Moreover, the success of this education three months after the educational program as compared to immediately and one month after it indicates that allocation of sufficient time plays a very important role in transferring information and in teaching methods of palliative care to old people.


2009 ◽  
Vol 21 (2) ◽  
pp. 131-139 ◽  
Author(s):  
B.J.A. Laird ◽  
M.T. Fallon

2021 ◽  
Author(s):  
Arpan A. Patel ◽  
Christopher Woodrell ◽  
Nneka N. Ufere ◽  
Lissi Hansen ◽  
Puneeta Tandon ◽  
...  

2016 ◽  
Vol 138 (09) ◽  
pp. S8-S13 ◽  
Author(s):  
Thiago Marinho ◽  
Christopher Widdowson ◽  
Amy Oetting ◽  
Arun Lakshmanan ◽  
Hang Cui ◽  
...  

This article demonstrates a multidisciplinary approach that proposes to augment future caregiving by prolonged independence of older adults. The human–robot system allows the elderly to cooperate with small flying robots through an appropriate interface. ASPIRE provides a platform where high-level controllers can be designed to provide a layer of abstraction between the high-level task requests, the perceptual needs of the users, and the physical demands of the robotic platforms. With a robust framework that has the capability to account for human perception and comfort level, one can provide perceived safety for older adults, and further, add expressively that facilitates communication and interaction continuously throughout the stimulation. The proposed framework relies on an iterative process of low-level controllers design through experimental data collected from psychological trials. Future work includes the exploration of multiple carebots to cooperatively assist in caregiving tasks based on human-centered design approach.


1983 ◽  
Vol 28 (2) ◽  
pp. 102-104 ◽  
Author(s):  
Martin G. Cole

Thirty-eight elderly patients with primary depressive illness (Feighner criteria) were followed up for 7–31 months. In the absence of persistent organic signs and severe physical illness, age of onset (first depressive episode after 60) but not age was significantly related to course of illness. Compared to early onset depressives, late onset depressives were more likely to remain completely well during the follow-up period and less likely to have frequent or disabling relapses.


F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 1793
Author(s):  
Emily J. Guerard ◽  
Gil E. Harmon ◽  
Kieran D. Sahasrabudhe ◽  
Noelle K. LoConte

This article summarizes the seminal publications from mid-2016 through 2017 in the area of medical care for older adults with cancer. Areas addressed include chemotherapy tolerance and efficacy in the aged, geriatric fitness assessments, and advancements in palliative and supportive care. The practice-changing finding from this past year’s publications is that antipsychotics should not be used in the management of terminal delirium in older adults receiving palliative care. The other trials demonstrated an improved understanding of the utility of geriatric assessments in patients with cancer, developed the body of information about which chemotherapy agents are safe and effective in older adults (and which are not), and expanded our understanding of good palliative and supportive care.


2021 ◽  
Vol 13 ◽  
Author(s):  
David Vogrinc ◽  
Katja Goričar ◽  
Vita Dolžan

Alzheimer's disease (AD) is a complex neurodegenerative disease, affecting a significant part of the population. The majority of AD cases occur in the elderly with a typical age of onset of the disease above 65 years. AD presents a major burden for the healthcare system and since population is rapidly aging, the burden of the disease will increase in the future. However, no effective drug treatment for a full-blown disease has been developed to date. The genetic background of AD is extensively studied; numerous genome-wide association studies (GWAS) identified significant genes associated with increased risk of AD development. This review summarizes more than 100 risk loci. Many of them may serve as biomarkers of AD progression, even in the preclinical stage of the disease. Furthermore, we used GWAS data to identify key pathways of AD pathogenesis: cellular processes, metabolic processes, biological regulation, localization, transport, regulation of cellular processes, and neurological system processes. Gene clustering into molecular pathways can provide background for identification of novel molecular targets and may support the development of tailored and personalized treatment of AD.


2021 ◽  
pp. 5-8
Author(s):  
E. I. Kovalenko ◽  
E. V. Artamonova

Elderly cancer patients represent a very heterogeneous pop ulation not only in chronological age, but also in functional status, concomitant diseases and therapy, geriatric syndromes and, as a consequence, in the tolerability of cancer treatment. The choice of chemotherapy (CT) for metastatic breast cancer in this category of patients is often a challenge for oncologists. Eribulin, a drug with a fairly good tolerance, has proven itself well both in randomized trials and in real clinical practice, including older patient population. Pooled analyzes of several studies have shown that the incidence of hematologic adverse events in elderly patients treated with eribulin does not exceed that in younger patients and does not generally affect the planned volume of treatment. At the same time, the elderly are more likely to experience side effects such as weakness, fatigue and polyneuropathy, which must be taken into account when planning CT. Only a comprehensive multidisciplinary approach with a geriatric assessment will make it possible to maximally individualize the approach to the treatment of this difficult category of patients.


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