scholarly journals Estimation and Human Health Risk Assessment of Organochlorine Pesticides in Raw Milk Marketed in Zagazig City, Egypt

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Amal A. Raslan ◽  
Seham Elbadry ◽  
Wageh Sobhy Darwish

Milk is nearly a perfect natural food and is widely used by all segments of our population especially for infants and the elderly. Organochlorine pesticides (OCPs) have been used worldwide, particularly in many African countries as in Egypt for the control of pests. OCPs are characterized by their bioaccumulation in the environment, especially in the food chain, where they find their way into the human body. The objectives of this study were initially to estimate the residual concentrations of different OCPs in three kinds of fresh and raw milk from different animals (cattle, buffalo, and goat) marketed in Egypt. Additionally, human dietary intake and risk assessment of OCPs were calculated. The tested OCPs included pp-DDT and its metabolites pp-DDD and pp-DDE; hexachlorohexanes (HCHs) including α HCH and γ HCH; heptachlor and heptachlor epoxide; aldrin and endrin; chlordane, methoxychlor, and hexachloride benzene. The recorded results revealed that goat and buffalo milk samples had the highest incidence of OCPs’ contamination (75% for each), while this percentage was 50% in cow’s milk. The mean values of ΣOCPs were 317.83 ± 34.11, 605 ± 50.54, and 1210.57 ± 99.55 (ppb/ww) in the examined cattle, buffalo, and goat milk samples, respectively. All examined OCPs were within the maximum permissible limits (MPLs) set by World Health Organization with only 10% of goat milk samples exceeding this MRL. The estimated daily intake, noncancer, and cancer health risk assessment of the tested OCPs revealed the potential cancer risk especially among children consuming goat’s milk. The public health importance of such OCPs was discussed.

Author(s):  
Chee Kong Yap ◽  
Azlini Razali ◽  
Rosimah Nulit ◽  
Shih Hao Tony Peng ◽  
Chee Wah Yap ◽  
...  

This study aimed to investigate the concentrations of copper (Cu), zinc (Zn), nickel (Ni), lead (Pb) and iron (Fe) in different parts of guava (pulps, peels and seeds) and its topsoil collected from Kluang, Malaysia, and to assess their effects on human health. The level of metals was determined using acid digestion method and atomic absorption spectrometry. The result showed that the concentrations of Cu, Zn and Pb in all parts of guava were above the World Health Organization (WHO) permissible limits. However, the value of heavy metals in the topsoil were below the WHO limit. The concentration order of the metals in the guava's pulps was Fe > Cu > Zn > Pb > Ni. The contamination factor (Cf ) calculated from the topsoil were low for Cu, Zn and Ni and moderate for Pb. However, potential ecological risk (Er) of individual metal ranged from 0.25-7.58 for Cu, Zn, Pb and Ni was low. The potential non-carcinogenic health risk for consumers was assessed using estimated daily intake (EDI) and target hazard quotient (THQ). The contribution of heavy metals to the EDI for all consumers followed the order of Fe > Cu > Zn > Pb > Ni. The THQ values are all below 1 for all five metals tested, indicating no potential risk to the consumers. We suggest that the Kluang's guava is safe to consume. However, regular monitoring and human health risk assessment of heavy metals in the guava is recommended to be carried out.


2020 ◽  
Vol 27 (23) ◽  
pp. 29567-29579 ◽  
Author(s):  
Zafar Iqbal ◽  
Farhat Abbas ◽  
Muhammad Ibrahim ◽  
Tahir Imran Qureshi ◽  
Matin Gul ◽  
...  

Molecules ◽  
2019 ◽  
Vol 24 (2) ◽  
pp. 248 ◽  
Author(s):  
Zhi-Hao Deng ◽  
Ang Zhang ◽  
Zhi-Wei Yang ◽  
Ya-Li Zhong ◽  
Jian Mu ◽  
...  

The concentrations of trace elements in wines and health risk assessment via wine consumption were investigated in 315 wines. Samples were collected from eight major wine-producing regions in China. The concentrations of twelve trace elements were determined by inductively coupled plasma mass spectrometry (ICP-MS) and Duncan’s multiple range test was applied to analyze significant variations (p < 0.05) of trace elements in different regions. Based on a 60 kg adult drinker consuming 200 mL of wine per day, the estimated daily intake (EDI) of each element from wines was far below the provisional tolerable daily intake (PTDI). Health risk assessment indicated the ingestion influence of individual elements and combined elements through this Chinese wine daily intake did not constitute a health hazard to people. However, Cr and Mn were the potential contaminants of higher health risk in Chinese wines. The cumulative impact of wine consumption on trace elements intake in the daily diet of drinkers should not be ignored due to the presence of other intake pathways.


2021 ◽  
Vol 9 (1) ◽  
pp. 184-191
Author(s):  
Sajad Faryabi ◽  
Mohsen Ghorbiani ◽  
Hadi Haghbin Nazarpak ◽  
Azadeh Rashidimehr

Introduction. Contamination of food, including animal protein sources, with heavy metals is a major threat to humans. The aim of this research was to determine lead concentrations in eggs from different Iranian regions and assess risks to human health. Study objects and methods. In this study, lead concentrations in eggs produced at laying hen farms in Qom, Isfahan (Kashan city), and Khorasan Razavi (Mashhad city) provinces were measured by an atomic absorption device. Health risk was estimated using the Human Health Risk Assessment (HHRA) model. Results and discussion. The levels of lead in eggs were significantly different (P ≤ 0.05) among the three regions. They were lower than the permissible limit (0.1 mg/kg) for Kashan (0.0756 mg/kg) and Mashhad (0.0633 mg/kg), but eggs from Qom contained 0.1163 mg/kg of lead. In all the three regions, the estimated daily intake (EDI) of lead was lower than the maximum tolerable daily intake (MTDI), indicating no health risk for lead through egg consumption among Iranian consumers. Also, no risks were detected for adults in terms of non-cancer risk, or target hazard quotients (THQ), and carcinogenic risk (CR) of lead (THQ < 1 and CR < 10–6). Conclusion. The results of this study indicated that lead health risk through egg consumption is within safe limits. However, the nutritional importance and high consumption of eggs among households necessitate a more careful monitoring of lead concentrations to meet public health requirements.


2018 ◽  
Vol 07 (04) ◽  
pp. 143-152 ◽  
Author(s):  
Samuel Oluyemi Adefemi ◽  
Samuel Sunday Asaolu ◽  
Olayinka Abidemi Ibigbami ◽  
Joshua Iseoluwa Orege ◽  
Mayowa Akeem Azeez ◽  
...  

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