scholarly journals Diagnosis and Treatment in a Tertiary Hospital of a Series of Complex Genital Malformations Corresponding to Double Uterus with Obstructed Hemivagina and Ipsilateral Renal Agenesis

2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Júlia Kefalás Troncon ◽  
Júlio César Rosa-e-Silva ◽  
Rayssa Miranda ◽  
Francisco José Candido-dos-Reis ◽  
Omero Benedicto Poli-Neto ◽  
...  

Aim. To evaluate the clinical features, diagnostic routine, treatment, and prognosis of patients with double uterus with obstructed hemivagina and ipsilateral renal agenesis at a University Hospital. Methods. A retrospective study analyzing the medical charts of outpatients with similar complex genital malformations seen at the University Hospital of the Ribeirão Preto Medical School from 1994 to 2015. Results. Fourteen patients were included in this retrospective study, all presenting with double uterus with obstructed hemivagina and ipsilateral renal agenesis. The main symptom was dysmenorrhea occurring shortly after menarche, and pelvic ultrasound was the examination of choice. The treatment consisted of resection of the vaginal septum, complemented by an abdominal approach in 5 cases. Complications of the syndrome observed in this case series included severe endometriosis, pelvic abscess, need for hysterectomy, and salpingectomy. Conclusions. Severe dysmenorrhea shortly after menarche is a typical symptom of this kind of malformation, even though the diagnosis of patients who present with fistulization of the vaginal septum can be delayed due to milder clinical features. Pelvic ultrasound can be considered the first-choice examination in diagnostic routine. Relief of pain and prevention of complications can be achieved successfully in most cases by resection of the vaginal septum.

2001 ◽  
Vol 115 (2) ◽  
pp. 112-118 ◽  
Author(s):  
A. Escribano Uzcudun ◽  
P. Bravo Fernández ◽  
J. J. Sánchez ◽  
A. García Grande ◽  
I. Rabanal Retolaza ◽  
...  

Pharyngeal cancer still presents an unsatisfactory mortality (30-40 per cent in most series, with a slightly better prognosis for nasopharyngeal cancer relative to both oropharyngeal and hypophyarngeal cancers) despite advances in treatment. Therefore, it is critical to know the clinical features of pharyngeal cancer. The purpose of this study was to investigate the most relevant clinical features of pharyngeal cancer (oropharyngeal, hypopharyngeal, and nasopharyngeal) in order to improve knowledge of this malignancy with the aim of ameliorating diagnosis and treatment.The retrospective study was based on a review of medical records from 258 consecutive patients with pharyngeal cancer (oropharyngeal, hypopharyngeal and nasopharyngeal) diagnosed at La Paz University Hospital, Madrid, Spain, between January 1 1991 and and December 31 1995. Medical records were provided by the Departments of Otorhinolaryngology, Head and Neck Surgery, Radiation Oncology, and Medical Oncology.All medical records were analysed for the following clinical variables: 1) incidence, 2) sociodemographics, 3) sites (oropharynx, hypopharynx, nasopharynx) and subsites, 4) clinical and histological staging, 5) pathlogy, 6) presenting symptoms, 7) time to diagnosis, 8) patients’ general performance status at diagnosis, 9) personal cancer history and synchronous head and neck tumours, 10) premalignant lesions, and 11) paediatric cases.Our most outstanding finding was the excessively long time that elapsed between first clinical manifestation appearance and conclusive diagnosis of pharyngeal cancer (4.7 months for pharynx, 4.5 for oropharynx, 4.4 for hypopharynx and 6.5 for nasopharynx cancers). It was found that nasopharyngeal cancer was quite different from both oropharyngeal and hypopharyngeal cancers with respect to its potential aetiology, risk factors and clinical presentation. In addition it has a better prognosis.


2004 ◽  
Vol 4 (2) ◽  
pp. 179-183 ◽  
Author(s):  
Alexandra Prufer de Queiroz Campos Araújo ◽  
Mariana Castro de Deco ◽  
Beatriz de Sá Klôh ◽  
Mariana Rangel da Costa ◽  
Fernanda Veiga de Góis ◽  
...  

OBJECTIVES: to study the clinical features of Duchenne Muscular Dystrophy with emphasis on diagnosis delay. METHODS: an observational descriptive retrospective study was performed using medical records of patients with diagnosis of Duchenne Muscular Dystrophy given in the period from 1989 to 2000 at the neuropediatric out-patient clinic of a University Hospital. RESULTS: immunohistochemical results or deletion on the dystrophin gene confirmed the diagnosis of the 78 boys included in this study. Parents had noticed the first symptoms since the median age of two years. The final diagnosis was reached at a median age of seven. CONCLUSIONS: diagnosis age is closer to the age of ambulation loss than that of the first symptoms. There is a marked delay for the diagnosis of this disease in our setting.


2019 ◽  
Vol 40 (S1) ◽  
pp. 193-194 ◽  
Author(s):  
Antonio Genovese ◽  
Arens Taga ◽  
Francesco Rausa ◽  
Simone Quintana ◽  
Gian Camillo Manzoni ◽  
...  

2006 ◽  
Vol 14 (3) ◽  
pp. 372-377 ◽  
Author(s):  
Paula Cristina Nogueira ◽  
Maria Helena Larcher Caliri ◽  
Vanderlei José Haas

Patients with traumatic spinal cord injury (TSCI) have an increased risk of developing pressure ulcers (PU). It is a retrospective study done by review of records in order to identify the characteristics of patients who were assisted at a tertiary hospital as well as the occurrence of PU. Most patients were male, white and 36,2% between 21 and 30 years. The most common causes of TSCI were wound by fire weapons followed by vehicle crash/overturn. There was a predominance of injury at the toracic level followed by cervical. The PU occurred in 20 pacientes (42,5%). The most frequent regions of occurrence were the sacral and heels. Only 25% of the records had PU's dimensions charted, 80% stated the aspect, and 52.1% did not state the stage. There is a need for better documentation of PU so that interventions used for treatment can be evaluated.


2020 ◽  
Vol 14 (1) ◽  
pp. 54-56
Author(s):  
Dilruba Zeba ◽  
Fahmida Zesmin ◽  
Rajib Roy

OHVIRA syndrome or Herlyn-Werner-Wunderlich syndrome is a rare congenital anomaly of female urogenital tract which is represented by the triad of uterine didelphys, obstructed hemivagina and ipsilateral renal agenesis. This rare variant of Müllerian duct anomalies represent failure of vertical and the lateral fusion of Müllerian ducts around 9 weeks of gestation. OHVIRA syndrome comprises about 2-3% of Müllerian abnormalities. A 13 years old girl got admission in FMCH on 15.3.2018 with lower abdominal pain and acute retention of urine. Her menarche was established 6 months back with regular cycle and associated with dysmenorrhoea. Imaging studies revealed uterine didelphys, highly dilated cervix with hematocolpos and absence of right kidney. The vaginal septum was excised. The patient recovered fully and was under follow up for 6 months. There was no evidence of further outflow tract obstruction. Faridpur Med. Coll. J. Jan 2019;14(1): 54-56


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Elham Shafighi Shahri ◽  
Seyed Hosein Soleimanzadeh Mousavi ◽  
Jamaladdin Osmani ◽  
Gholamreza Soleimani

Objectives: To investigate the epidemiology, clinical features, and treatment of hospitalized pediatric cases of preseptal and orbital cellulitis in a central university hospital in Zahedan, Iran. Methods: Retrospective study of children/adolescents admitted to a central university hospital with orbital and preseptal cellulitis from 2016 to 2018. Results: Forty patients, including 29 cases of preseptal cellulitis and 11 cases of orbital cellulitis, were included in the study. The prevalence of orbital and preseptal cellulitis was approximately the same in both sexes. Mean age was 2.86 ± 0.56 years (ranges 12 days to 13 years) in patients with orbital cellulitis and 2.82 ± 0.67 years (range, 2 months to 8 years) in patients with preseptal cellulitis. The most common clinical and paraclinical findings were edema of the eyelids and increased ESR, respectively. Sinusitis is the most common underlying cause, which was present in 63.63% of cases of orbital cellulitis and 34.48% of cases of preseptal cellulitis. The most frequent antibiotics used in this study were ceftriaxone, cloxacillin, and vancomycin. Conclusions: The most common clinical and paraclinical findings were edema of the eyelids and increased ESR, respectively. Sinusitis is the most common underlying cause. Timely treatment of sinusitis may prevent orbital and preseptal cellulitis.


2021 ◽  
Vol 14 (2) ◽  
pp. e239625
Author(s):  
Vikas Kumar Panwar ◽  
Tushar Aditya Narain ◽  
Ankur Mittal ◽  
Harkirat Singh Talwar

The obstructed hemivagina and ipsilateral renal agenesis (OHVIRA) syndrome, a rare Mullerian duct anomaly, is a triad of uterine anomalies with ipsilateral renal agenesis and obstructed hemivagina. The aetiopathogenesis of this developmental anomaly is debatable, with several theories being postulated to explain its occurrence. We report two cases of this rare syndrome which were detected on imaging done for unrelated reasons. Case 1 is a 24-year-old woman who presented with primary infertility. After an incidental detection of the syndrome and ruling out a male factor, she has been planned for excision of the vaginal septum. Case 2 is a 47-year-old woman with OHVIRA detected during the evaluation of urolithiasis and is asymptomatic for the syndrome. The OHVIRA syndrome can be asymptomatic or may present as haematocolpos, pelvic pain and infertility which requires surgical intervention, after which successful pregnancies have been reported.


2021 ◽  
pp. 1-8
Author(s):  
Pamela Grace Vidal Valera ◽  
Madonna Victoria Calderon Domingo

The Herlyn–Werner–Wunderlich (HWW) syndrome is an uncommon Mullerian duct anomaly composed of a triad of obstructed hemivagina, renal agenesis, uterine didelphys with a prevalence of [Formula: see text] females. Aside from its usual presentation of cyclic hypogastric pain and abdominal mass, there has been no other reported case in literature of the syndrome presenting with a vagino-umbilical fistula. Presented here is a unique case of a 35-year-old woman presenting with purulent, foul-smelling discharge extruding from a fistula on her umbilicus and her vagina associated with a tender hypogastric mass. Three-dimensional transvaginal ultrasonography aided the diagnosis of HWW syndrome with a concomitant vagino-umbilical fistula. Excision of the vaginal septum together with antibiotic coverage resolved her symptoms. The syndrome’s embryopathogenesis, classification, diagnostics, definitive surgical management and other issues during follow up are discussed.


2005 ◽  
Vol 21 (1-2) ◽  
pp. 42-44
Author(s):  
Edgardo Abelardo ◽  
Tetsuji Sanuki ◽  
Eiji Yumoto

Objectives: To propose a simple technique to preserve, medialize and stabilize the middle turbinate through a planned medial synechiae formation using a nasal septal flap   Methods: Study Design: Case series, surgical innovation Setting: Tertiary hospital (Kumamoto University Hospital, Japan) Participants, Patients or Population: Six patients suffering from chronic sinusitis unresponsive to medication. The indication for doing this technique was unstable turbinates after removal of diseased mucosa.   Results: Twelve weeks after surgery, the patients reported significant resolution of symptoms (headache, nasal congestion, rhinorrhea, post-nasal drip and loss of smell). CT and endoscopic findings likewise revealed clear ostio-meatal complex, drained sinuses, and complete removal of polypoid mucosa. No major side effects were noted.   Conclusions: This technique is especially encouraged when surgeons encounter an unstable middle turbinate after removing massive pathologic mucosal lesions. This is a preliminary report and further investigations are being carried out to validate the technique.   Keywords: medial synechiae, nasal septal flap, ostio-meatal complex    


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