scholarly journals A Unique Case of Midvariant Reverse Takotsubo Cardiomyopathy

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Carmel Moazez ◽  
Vicken Zeitjian ◽  
Azar Mehdizadeh

Takotsubo cardiomyopathy, also known as stress cardiomyopathy, is known to have 4 variants: apical, midventricular, basal, and focal. Here, we report the 2nd case of reverse midvariant (midventricular) stress cardiomyopathy and the 1st case of reverse midvariant takotsubo cardiomyopathy with apical thrombus.

2013 ◽  
Vol 154 (7) ◽  
pp. 267-271 ◽  
Author(s):  
János Tomcsányi ◽  
Kinga Jávor ◽  
Hrisula Arabadzisz ◽  
András Zsoldos ◽  
Vince Wagner ◽  
...  

The authors describe two cases of takotsubo cardiomyopathy developing after an abrupt withdrawal of carvedilol and bisoprolol. Takotsubo or stress cardiomyopathy is characterized by acute and reversible cardiac dysfunction without coronary artery disease. It is triggered by acute emotional or physical stress, drugs or drug withdrawal. The immediate discontinuation of the long acting vasodilator beta-blocker, carvedilol has not yet been described to cause takotsubo cardiomyopathy. The authors recommend cautious withdrawal of beta-blockers. Orv. Hetil., 2013, 154, 267–271.


2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
Anusha Battineni ◽  
Naresh Mullaguri ◽  
Shail Thanki ◽  
Anand Chockalingam ◽  
Raghav Govindarajan

Introduction. Patients with myasthenia crisis can develop Takotsubo stress cardiomyopathy (SC) due to emotional or physical stress and high level of circulating catecholamines. We report a patient who developed recurrent Takotsubo cardiomyopathy during myasthenia crisis. Coexisting autoimmune disorders known to precipitate stress cardiomyopathy like Grave’s disease need to be evaluated. Case Report. A 69-year-old female with seropositive myasthenia gravis (MG), Grave’s disease, and coronary artery disease on monthly infusion of intravenous immunoglobulin (IVIG), prednisone, pyridostigmine, and methimazole presented with shortness of breath and chest pain. Electrocardiogram (ECG) showed ST elevation in anterolateral leads with troponemia. Coronary angiogram was unremarkable for occlusive coronary disease with left ventriculogram showing reduced wall motion with apical and mid left ventricle (LV) hypokinesis suggestive of Takotsubo stress cardiomyopathy. Her symptoms were attributed to MG crisis. Her symptoms, ECG, and echocardiographic findings resolved after five cycles of plasma exchange (PLEX). She had another similar episode one year later during myasthenia crisis with subsequent resolution in 10 days after PLEX. Conclusion. Takotsubo cardiomyopathy can be one of the manifestations of myasthenia crisis with or without coexisting Grave’s disease. These patients might benefit from meticulous fluid status and cardiac monitoring while administering rescue treatments like IVIG and PLEX.


2009 ◽  
Vol 15 (7) ◽  
pp. S159 ◽  
Author(s):  
Toyoji Kaida ◽  
Hironari Nakano ◽  
Ichiro Watanabe ◽  
Makoto Nishinari ◽  
Nakako Yasuno ◽  
...  

2010 ◽  
Vol 103 (8) ◽  
pp. 805-806 ◽  
Author(s):  
Himanshu Pathak ◽  
Jason Esses ◽  
Swati Pathak ◽  
Robert Frankel ◽  
Gerald Hollander

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 518
Author(s):  
Navid Ahmed ◽  
Himali Gandhi ◽  
Daniel B. Sims

Takotsubo cardiomyopathy (TTC), also known as stress-induced cardiomyopathy, is a cardiac syndrome that often mimics acute myocardial infarction. TTC is commonly triggered by physical or emotional stress; however, acute infection is a rarer etiology. This report concerns the case of an 82-year-old female who presented with non-positional and non-pleuritic chest pain, with an associated fever and cough and chest x-ray findings consistent with pneumonia. Cardiac enzymes and ECG findings were consistent with acute coronary syndrome (ACS); however, during coronary angiography, no coronary artery disease could explain the patient’s ACS. A post-catheterization echocardiogram revealed an ejection fraction of 25%, with apical akinesis. A repeat echocardiogram 4 weeks after presentation showed a normal EF and normal wall motion, confirming a diagnosis of TTC.


Author(s):  
Sanja Sakan ◽  
Petar Matosevic ◽  
Daniela Bandic Pavlovic ◽  
Iva Rukavina ◽  
Jelena Magas Vadlja ◽  
...  

Stress cardiomyopathy or Takotsubo cardiomyopathy is a new syndrome and still insufficiently recognized among emergency patients, hospitalized patients. Many different physical and emotional stressors are triggers, but individual susceptibility to Takotsubo cardiomyopathy can not be predicted. Takotsubo cardiomyopathy in surgical and critical care population is a huge diagnostic challenge. Apart that these patients are treated in stressful environment and conditions. Postoperatively due to change of consciousness and inability to speak we can not rely on verbal symptoms to make differential diagnosis. Although essential sometimes they can not be submitted to coronary angiography to exclude obstructive coronary disease due many risk factors. So, then we follow clinical course, electrocardiographic, radiologic and echocardiographic dynamic changes, laboratory findings and consiliar opinion to make diagnosis. We represent a case of Takotsubo cardiomyopathy in a 59-years old postmenopausal Caucasian woman after tracheal extubation. She was submitted to surgery of intraabdominal collection evacuation in short general endotracheal anesthesia.


Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Elena Salmoirago-Blotcher ◽  
Sandhya Reddy ◽  
Robert J Goldberg ◽  
Darleen M Lessard ◽  
Timothy Fitzgibbons ◽  
...  

Background: Transient Stress Cardiomyopathy (TSC) is a reversible condition mimicking acute myocardial infarction that frequently affects postmenopausal women and is often triggered by emotional or physical stress. Limited information is available about the long-term prognosis of this condition as previous studies were mostly case series and/or were unable to adjust for several confounding variables. The aim of this retrospective cohort study was to assess the post-hospital discharge prognosis of women diagnosed with TSC compared with historical ST-elevation myocardial infarction (STEMI) female controls. The principal study outcome was a composite of cardiovascular (CV) hospital readmissions and death from any cause. Methods: Cases were identified by reviewing the charts of consecutive women hospitalized at UMass Memorial Medical Center in Worcester, MA, with an ICD-9 code of 429.83 (Takotsubo cardiomyopathy) from 01/2002 until 06/2012. To be eligible, cases had to fulfill all Mayo clinic criteria for TSC. Controls were randomly selected (2:1 ratio) among women with a validated diagnosis of STEMI enrolled in the Worcester Heart Attack Study during the same period. Clinical characteristics and information about CV readmissions and death were abstracted from the medical record. Survival curves were generated by the Kaplan-Meier method. Log-rank statistics was used to compare survival curves. Risk of death or CV readmissions (with the STEMI category as the referent) was estimated from multivariate Cox proportional hazard regression models adjusted for variables associated with the composite outcome. Results: Out of 356 consecutive women hospitalized with an ICD-9 code of 429.83 (Takotsubo cardiomyopathy), 50 met Mayo diagnostic criteria. Baseline age was 65±14 years in TSC cases and 71 ±15 in STEMI controls (n=100). The prevalence of coronary risk factors, and of a history of angina, stroke and heart failure, was lower among TSC cases vs. controls. At admission, TSC women had lower peak CK, troponin I levels and SBP values; mean (angiogram) ejection fraction was 0.32 in TSC and 0.47 in STEMI women. TSC cases were less frequently prescribed aspirin, beta-blockers, lipid lowering agents and ACE inhibitors at hospital discharge. Over an overall average follow-up of 2 years, incidence rates of the composite outcome were 140/1,000 person-years among women with TSC and 347/1,000 person-years among those with STEMI. In multivariate adjusted models, the hazard ratio for the composite endpoint in TSC vs. STEMI women was 0.50 (CI: 0.26,0.98). Conclusion: Women diagnosed with TSC had a significantly better post-discharge prognosis than women with STEMI. However, mortality and CV readmissions rates among TSC women were relatively high, indicating that TSC is not a benign condition.


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