scholarly journals Stenotrophomonas maltophilia Meningitis in a Term Healthy Neonate: A Case Report and Literature Review

2018 ◽  
Vol 2018 ◽  
pp. 1-3 ◽  
Author(s):  
Judy Ibrahim ◽  
Nadia Hamwi ◽  
Hala Rabei ◽  
Mohamed Abdelghafar ◽  
Zahraa Al-Dulaimi ◽  
...  

Stenotrophomonas maltophilia is an environmental bacterium of growing concern due to its multidrug resistance and pathogenic potential. It is considered an opportunistic pathogen of nosocomial origin most of the time, targeting a specific patients' population. We describe a case of a previously healthy full-term neonate who was found to have S. maltophilia meningitis and was successfully treated with a combination of Trimethoprim-Sulfamethoxazole and Ciprofloxacin.

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Vinicius Godoy Cerezer ◽  
Silvia Yumi Bando ◽  
Jacyr Pasternak ◽  
Marcia Regina Franzolin ◽  
Carlos Alberto Moreira-Filho

Stenotrophomonasssp. has a wide environmental distribution and is also found as an opportunistic pathogen, causing nosocomial or community-acquired infections. One species,S. maltophilia, presents multidrug resistance and has been associated with serious infections in pediatric and immunocompromised patients. Therefore, it is relevant to conduct resistance profile and phylogenetic studies in clinical isolates for identifying infection origins and isolates with augmented pathogenic potential. Here, multilocus sequence typing was performed for phylogenetic analysis of nosocomial isolates ofStenotrophomonasspp. and, environmental and clinical strains ofS. maltophilia. Biochemical and multidrug resistance profiles of nosocomial and clinical strains were determined. The inferred phylogenetic profile showed high clonal variability, what correlates with the adaptability process ofStenotrophomonasto different habitats. Two clinical isolates subgroups ofS. maltophiliasharing high phylogenetic homogeneity presented intergroup recombination, thus indicating the high permittivity to horizontal gene transfer, a mechanism involved in the acquisition of antibiotic resistance and expression of virulence factors. For most of the clinical strains, phylogenetic inference was made using only partialppsA gene sequence. Therefore, the sequencing of just one specific fragment of this gene would allow, in many cases, determining whether the infection withS. maltophiliawas nosocomial or community-acquired.


2003 ◽  
Vol 38 (11) ◽  
pp. 1665-1666 ◽  
Author(s):  
Jeroen Heemskerk ◽  
George H Sie ◽  
Anita M Van den Neucker ◽  
Pierre-Philippe Forget ◽  
Erik Heineman ◽  
...  

2008 ◽  
Vol 47 (10) ◽  
pp. 1056-1057 ◽  
Author(s):  
Patrícia Mesquita Couto Azevedo ◽  
Maria Fernanda Reis Gavazzoni-Dias ◽  
João Carlos Regazzi Avelleira ◽  
Cláudio Lerer ◽  
Aline Soares de Sousa ◽  
...  

2014 ◽  
Vol 2 (5) ◽  
pp. 250-253 ◽  
Author(s):  
Nick Zavras ◽  
Constantinos Siafakas ◽  
George Pergamalis ◽  
Yvelise de Verney ◽  
Maria Clavdianou ◽  
...  

2017 ◽  
Vol 73 (5) ◽  
pp. 647-649 ◽  
Author(s):  
Pavla Pokorná ◽  
Karolina Hronová ◽  
Martin Šíma ◽  
Ondřej Slanař ◽  
Petr Klement ◽  
...  

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