scholarly journals A Novel Interpretation for Arterial Pulse Pressure Amplification in Health and Disease

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Manuel R. Alfonso ◽  
Ricardo L. Armentano ◽  
Leandro J. Cymberknop ◽  
Arthur R. Ghigo ◽  
Franco M. Pessana ◽  
...  

Arterial pressure waves have been described in one dimension using several approaches, such as lumped (Windkessel) or distributed (using Navier-Stokes equations) models. An alternative approach consists of modeling blood pressure waves using a Korteweg-de Vries (KdV) equation and representing pressure waves as combinations of solitons. This model captures many key features of wave propagation in the systemic network and, in particular, pulse pressure amplification (PPA), which is a mechanical biomarker of cardiovascular risk. The main objective of this work is to compare the propagation dynamics described by a KdV equation in a human-like arterial tree using acquired pressure waves. Furthermore, we analyzed the ability of our model to reproduce induced elastic changes in PPA due to different pathological conditions. To this end, numerical simulations were performed using acquired central pressure signals from different subject groups (young, adults, and hypertensive) as input and then comparing the output of the model with measured radial artery pressure waveforms. Pathological conditions were modeled as changes in arterial elasticity (E). Numerical results showed that the model was able to propagate acquired pressure waveforms and to reproduce PPA variations as a consequence of elastic changes. Calculated elasticity for each group was in accordance with the existing literature.

1999 ◽  
Vol 276 (1) ◽  
pp. H257-H268 ◽  
Author(s):  
Mette S. Olufsen

A central problem in modeling blood flow and pressure in the larger systemic arteries is determining a physiologically based boundary condition so that the arterial tree can be truncated after a few generations. We have used a structured tree attached to the terminal branches of the truncated arterial tree in which the root impedance is estimated using a semianalytical approach based on a linearization of the viscous axisymmetric Navier-Stokes equations. This provides a dynamic boundary condition that maintains the phase lag between blood flow and pressure as well as the high-frequency oscillations present in the impedance spectra. Furthermore, it accommodates the wave propagation effects for the entire systemic arterial tree. The result is a model that is physiologically adequate as well as computationally feasible. For validation, we have compared the structured tree model with a pure resistance and a windkessel model as well as with measured data.


2012 ◽  
Vol 605-607 ◽  
pp. 2506-2509 ◽  
Author(s):  
Zhang Xia Guo ◽  
Yu Tian Pan ◽  
Kui Wu Li ◽  
Hai Yan Zhang

The high pressure waves created due to muzzle blast flowfield through the gun barrel during firing is a critical issue to examine. The impulsive noise from the gun has various negative effects such as damage of human bodies, damage of structures, creating an environmental, social problem and also military problems, so beyond the range of a flow field was simulated numerically. The calculation was based on the 2D axial symmetry Navier-Stokes equations and standard k-ε turbulence model. From numerical simulations, wave dynamic processes are simulated and discussed. The pressure variation of the blast flowfield is analyzed , The results of this study will be helpful in understanding muzzle blast wave and designing silencer .


Author(s):  
Ayaka Imamura ◽  
Nozomu Hatakeyama ◽  
Osamu Inoue

The sound generated by a squarer cylinder in a uniform flow is investigated by direct numerical simulation of the two-dimensional compressible Navier–Stokes equations. The characteristic features of the generated sound are investigated and compared for different configurations and angles of attack. Results show that sound pressure waves are generated by vortex shedding from the cylinder into its wake. The sound field is dominated by lift dipole. The effect of the angle of attack on the sound generation and propagation is also analyzed.


Author(s):  
Manuel Rodri´guez Ferna´ndez ◽  
Evangelino Garrido Torres ◽  
Ricardo Ortega Garci´a

During the last decades, high speed railway traffic system has achieved a great development all over the world. Increasing speed in the train circulation implies the apparition of new aerodynamic phenomena that need to be studied. One of these problems has to do with the entrance and exit of high speed (HS) trains in tunnels. When this occurs, pressure waves propagate and reflect through the tunnel at sound speed, generating a non-stationary movement of the air which depends greatly on the speed of the train and the geometry between train and tunnel. A study has been carried on to determine the pressure and velocity fields of air inside the tunnel when the train passes through. As a result of this study, a new software, “TrenSen”, has been developed. This program solves numerically a particular case of the Navier-Stokes equations, a hyperbolic system of partial differential equations which describe the flow behaviour inside the tunnel. In the first section of the paper presented hereby a description of the algebra for the fluid dynamics equations is conducted. The second section will explain some features of the software, ending with some numerical results obtained from the program. To finish the paper, the software is validated by comparing the numeric results with available experimental data and with some other commercial software.


2020 ◽  
Vol 14 (4) ◽  
pp. 7369-7378
Author(s):  
Ky-Quang Pham ◽  
Xuan-Truong Le ◽  
Cong-Truong Dinh

Splitter blades located between stator blades in a single-stage axial compressor were proposed and investigated in this work to find their effects on aerodynamic performance and operating stability. Aerodynamic performance of the compressor was evaluated using three-dimensional Reynolds-averaged Navier-Stokes equations using the k-e turbulence model with a scalable wall function. The numerical results for the typical performance parameters without stator splitter blades were validated in comparison with experimental data. The numerical results of a parametric study using four geometric parameters (chord length, coverage angle, height and position) of the stator splitter blades showed that the operational stability of the single-stage axial compressor enhances remarkably using the stator splitter blades. The splitters were effective in suppressing flow separation in the stator domain of the compressor at near-stall condition which affects considerably the aerodynamic performance of the compressor.


AIAA Journal ◽  
2001 ◽  
Vol 39 ◽  
pp. 56-63
Author(s):  
W. Kyle Anderson ◽  
James C. Newman ◽  
David L. Whitfield ◽  
Eric J. Nielsen

AIAA Journal ◽  
2000 ◽  
Vol 38 ◽  
pp. 1603-1614
Author(s):  
Martin Scholtysik ◽  
Bernhard Mueller ◽  
Torstein K. Fannelop

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