scholarly journals Maxillary Sinus Floor Augmentation Using an Equine-Derived Graft Material: Preliminary Results in 17 Patients

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
F. Rivara ◽  
M. Negri ◽  
S. Lumetti ◽  
L. Parisi ◽  
A. Toffoli ◽  
...  

Objective. Sinus floor elevation with lateral approach is probably the most frequently performed reconstructive procedure to rehabilitate posterior maxilla when a bone deficiency is present. Different graft materials have been proposed and tested, often with high clinical performances and predictable results. Histological analysis is required when evaluating new materials. We investigated human biopsies retrieved after sinus floor elevation procedure by histomorphometric evaluation to test the performance of an equine-derived bone grafting material. Study Design. Seventeen consecutive patients were enrolled and sinus lift surgeries were performed using an equine bone graft. Six months after surgery, at implant placement, bone samples were collected. Histomorphometry analysis was carried out on decalcified samples. Results. All surgeries were uneventful and no additional grafting was required prior to implant insertion. Forty percent of new bone formation was detected, which represented the most abundant tissue retrieved, followed by the residual graft material (33%) and fibrous tissue (27%). A significant reduction in particles size demonstrates a remodeling activity of the graft material. Conclusion. Within the limitations of this study, this equine-derived bone graft proved to be an effective material to induce new bone formation in the sinus floor elevation procedure.

2017 ◽  
Vol 26 (2) ◽  
pp. 209-216 ◽  
Author(s):  
Teresa Lombardi ◽  
Claudio Stacchi ◽  
Federico Berton ◽  
Tonino Traini ◽  
Lucio Torelli ◽  
...  

2020 ◽  
Vol 9 (11) ◽  
pp. 3764
Author(s):  
Sangyup Kim ◽  
Jong-Hyuk Chung ◽  
Seung-Yun Shin ◽  
Seung-Il Shin ◽  
Ji-Youn Hong ◽  
...  

Schneiderian membrane perforation (SMP) is the most common complication during sinus floor elevation (SFE). Conventional methods to repair SMP, such as using a collagen barrier, may be clinically demanding. The aim of the present study was to compare the effects of collagenated bone substitute materials with and without a collagen barrier to repair SMP during SFE in terms of new bone formation and dimensional stability. In 12 rabbits, intentional SMP was made during bilateral SFE. The rabbits were randomly assigned under two groups: the control group, in which the sinus was repaired with a collagen barrier, and the test group, in which the sinus was repaired without a collagen barrier. Collagenated bone substitute material was grafted in both groups. Healing periods of 2 weeks and 4 weeks were provided in both groups. There were no adverse clinical events. Histology revealed that the Schneiderian membrane had atrophied with loss of cilia and serous glands in both groups at 4 weeks. Histomorphometry revealed that the newly formed bone (test: 0.42 ± 0.17 mm2, control: 0.36 ± 0.18 mm2 at 2 weeks; test: 1.21 ± 0.36 mm2, control: 1.23 ± 0.55 mm2 at 4 weeks) or total augmented area did not significantly differ between the two groups at either time points (p > 0.05). In conclusion, collagenated bone substitute material without a collagen barrier demonstrated similar new bone formation and dimensional stability as that with a collagen barrier in repairing SMP.


2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Mario Beretta ◽  
Marco Cicciù ◽  
Ennio Bramanti ◽  
Carlo Maiorana

Maxillary sinus floor elevation via a lateral approach is a predictable technique to increase bone volume of the edentulous posterior maxilla and consequently for dental implants placement. The sinus floor is elevated and it can be augmented with either autologous or xenogeneic bone grafts following an opening bone window created on the facial buccal wall. Maxillary septa are walls of cortical bone within the maxillary sinus. The septa shape has been described as an inverted gothic arch arising from the inferior or lateral walls of the sinus and may even divide the sinus into two or more cavities. Some authors have reported a higher prevalence of septa in atrophic edentulous areas than in nonatrophic ones. Radiographic identification of these structures is important in order to perform the right design of the lateral window during sinus lift. Aim of this investigation is to highlight the correct steps for doing sinus lift surgery in presence of those anatomic variations. Clinicians should always perform clinical and radiographic diagnosis in order to avoid complications related to the sinus lift surgery.


2006 ◽  
Vol 309-311 ◽  
pp. 427-432 ◽  
Author(s):  
Y. Kim ◽  
Y.H. Kown ◽  
J.B. Park ◽  
J.H. Chung ◽  
H.N. Lim ◽  
...  

The purpose of this study was to examine if the application of custom-made porous titanium membranes combined with bone graft materials promotes exophytic bone formation in rabbit calvaria. For this purpose, round decorticated calvaria sites were created using a round carbide bur. In the control group, rectangular parallelepiped-shaped porous titanium membranes (RPTMs) were placed on the decorticated sites and fixed with metal pins. In the experimental groups, RPTMs were filled with one of the following bone graft materials prior to fixing with metal pins: bovine bone mineral (BBM), demineralized freeze-dried human cortical bone (DFDB) or freeze-dried human cancellous bone (FDB). Animals were sacrificed at 8 and 12 weeks after surgery, and new bone formation was assessed by histomorphometric as well as statistical analysis. The results indicate that at 8 and 12 weeks, all the experimental groups demonstrated exophytic bone formation. At 12 weeks, DFDB group revealed the most new bone formation (p<0.05) and resorption of grafted materials (p<0.05). On the basis of these findings, we conclude that RPTMs may be used as an augmentation membrane for guided bone regeneration and DFDB as an effective bone-inducing graft material.


2013 ◽  
Vol 7 (1) ◽  
pp. 18-24 ◽  
Author(s):  
Jeppe Barckman ◽  
Jorgen Baas ◽  
Mette Sørensen ◽  
Joan E Bechtold ◽  
Kjeld Soballe

Purpose: Periosteum provides essential cellular and biological components necessary for fracture healing and bone repair. We hypothesized that augmenting allograft bone by adding fragmented autologous periosteum would improve fixation of grafted implants. Methods: In each of twelve dogs, we implanted two unloaded cylindrical (10 mm x 6 mm) titanium implants into the distal femur. The implants were surrounded by a 2.5-mm gap into which morselized allograft bone with or without addition of fragmented autologous periosteum was impacted. After four weeks, the animals were euthanized and the implants were evaluated by histomorphometric analysis and mechanical push-out test. Results: Although less new bone was found on the implant surface and increased volume of fibrous tissue was present in the gap around the implant, no difference was found between treatment groups regarding the mechanical parameters. Increased new bone formation was observed in the immediate vicinity of the periosteum fragments within the bone graft. Conclusion: The method for periosteal augmentation used in this study did not alter the mechanical fixation although osseointegration was impaired. The observed activity of new bone formation at the boundary of the periosteum fragments may indicate maintained bone stimulating properties of the transplanted cambium layer. Augmenting the bone graft by smaller fragments of periosteum, isolated cambium layer tissue or cultured periosteal cells could be studied in the future.


2018 ◽  
Vol 29 (5) ◽  
pp. 465-479 ◽  
Author(s):  
Claudio Stacchi ◽  
Teresa Lombardi ◽  
Roberto Ottonelli ◽  
Federico Berton ◽  
Giuseppe Perinetti ◽  
...  

2019 ◽  
Author(s):  
Zhaoguo Yue ◽  
Qi Liu ◽  
Haidong Zhang ◽  
Jingwen Yang ◽  
Yalin Zhan ◽  
...  

Abstract Background Residual alveolar bone volume is a critical factor for the dental implants’ survival [1]. When the volume of alveolar bone in the posterior maxillary region is less than 4mm, the maxillary sinus floor elevation (MSFE) with lateral approach is an effective way to solve this problem [2]. Traditionally, this standard approach is usually delivered 4 months after the extraction of the tooth. However, the defective dentition due to the extraction would cause impaired masticatory function during the long period of the bone regeneration, especially when molars on both sides are severely periodontal compromised and need to be extracted. So, as periodontists, we start to wonder if we can maintain a compromised tooth so that we perform the sinus floor elevation before the extraction (the modified MSFE) to take fully advantage of residual strength of the teeth. Methods/Design The proposed study is designed as a prospective single-center, split-mouth design, randomized controlled trial. We plan to recruit 10 patients whose molars on both sides are severely periodontal compromised and in need of dental implant treatment in the atrophied posterior maxilla. The two sides of each patients will be divided into two groups randomly using Randomizer for Clinical Trials (Institute for Medical Informatics, Statistics and Documentation, Medical Univ. Graz). Test group: sinus floor augmentation before tooth extraction (the modified MSFE); Control group: sinus floor augmentation after tooth extraction (the standard MSFE). Implant survival rates, mucosal conditions around the implants, complications, treatment time and postoperative discomfort (visual analogue scale for intraoperative pain and postoperative pain/discomfort) will be recorded. The volume of the alveolar bone will be measured 6, 12, 18, and 24 months after the MSFE surgery by means of CBCT. Histological and histomorphometic analysis will be performed on biopsies retrieved from both side of grafting sites. Discussion The current study will explore the effectiveness of the modified MSFE on minimizing the discomfort period caused by defected dentition. To determine whether the modified MSFE will promote the grafting outcomes, the quality and the quantity of the osteogenesis on the sinus floor will also be compared. Depending on the result of the current study, we will determine all the protocols and details about the modified MSFE, including indications, detailed methods, post-operational complications and managements.


Sign in / Sign up

Export Citation Format

Share Document