scholarly journals Spontaneous Renal Allograft Rupture Caused by Acute Tubular Necrosis: A Case Report and Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Deepak Shankar Ray ◽  
Sharmila Thukral

Renal allograft rupture (RAR) is a rare but lethal complication of renal transplantation. It potentially threatens graft and patient survival. RAR is frequently associated with acute rejection, but other causes like renal vein thrombosis and acute tubular necrosis have also been observed. Most commonly a graft nephrectomy is required, but graft repair can also be attempted in selected cases to salvage the graft. Herein, we describe a rare case of spontaneous renal allograft rupture in the early posttransplant period due to acute tubular necrosis. A 42-year-old male, living donor renal allograft recipient, experienced RAR on the sixth posttransplant day. Surgical exploration showed two lacerations of 10 cm and 5 cm length at the upper and mid pole of the kidney. Histologically, the graft demonstrated acute tubular injury; no features of humoral or cellular rejection were identified. The successful management of this complication resulted in the salvage of the patient and the graft. This case demonstrates that early diagnosis and prompt treatment of a life-threatening RAR can salvage the graft.

2001 ◽  
Vol 16 (1) ◽  
pp. 124-127 ◽  
Author(s):  
Boris Wolfgang Hochleitner ◽  
Reinhold Kafka ◽  
Bernard Spechtenhauser ◽  
Claudia Bösmüller ◽  
Wolfgang Steurer ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Shona Baker ◽  
Maria Popescu ◽  
Jacob A. Akoh

Background. Rupture of renal allograft is a rare and serious complication of transplantation that is usually attributed to acute rejection, acute tubular necrosis, or renal vein thrombosis.Case Presentation. LD, a 26-year-old male with established renal failure, underwent deceased donor transplantation using kidney from a 50-year-old donor with acute kidney injury (Cr 430 mmol/L). LD had a stormy posttransplant recovery and required exploration immediately for significant bleeding. On day three after transplant, he developed pain/graft swelling and another significant haemorrhage with cardiovascular compromise which did not respond to aggressive resuscitation. At reexploration, the renal allograft was found to have a longitudinal rupture and was removed. Histology showed features of type IIa Banff 97 acute vascular rejection, moderate arteriosclerosis, and acute tubular necrosis.Conclusion. Possible ways of avoiding allograft rupture include use of well-matched, good quality kidneys; reducing or managing risk factors that would predispose to delayed graft function; ensuring a technically satisfactory transplant procedure with short cold and warm ischemia times; and avoiding large donor-recipient age gradients.


Nephrology ◽  
2003 ◽  
Vol 8 (5) ◽  
pp. 248-250 ◽  
Author(s):  
WAI H LIM ◽  
GREG VAN SCHIE ◽  
KEVIN WARR

2006 ◽  
Vol 67 (8) ◽  
pp. 438-438 ◽  
Author(s):  
SA Summers ◽  
W Partridge ◽  
C Laing ◽  
PR Cook

2016 ◽  
Vol 10 (2) ◽  
pp. 40-42
Author(s):  
Vaidehi K. Pandya ◽  
Harsh C. Sutariya

2004 ◽  
Vol 36 (10) ◽  
pp. 2997-3001 ◽  
Author(s):  
S.A. Lopes de Souza ◽  
L.M. Barbosa da Fonseca ◽  
R. Torres Gonçalves ◽  
D. Salomão Pontes ◽  
T.J. Holzer ◽  
...  

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