scholarly journals A Subdermal Osteochondroma in a Young Girl

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Heather A. Cole ◽  
Hernan Correa ◽  
Jonathan G. Schoenecker
Keyword(s):  
Growth Plate ◽  
Subcutaneous Tissue ◽  
Excisional Biopsy ◽  
Benign Tumors ◽  
Deep Fascia ◽  
Long Bones ◽  
Imaging Studies ◽  
Dermal Layer ◽  
Slow Growing ◽  
Growing Mass

Osteochondromas are common benign tumors of cartilage and bone. They are usually found as contiguous bone with a cartilage cap at the end of the growth plate of long bones. Similar to structure are extraskeletal osteochondromas. However, unlike typical osteochondromas, extraskeletal osteochondromas are noncontinuous with bone. To our knowledge, all reported extraskeletal osteochondromas have been contained within fascial compartments. Here we present the case of a 5-year-old female who had a slow growing mass of the anterior distal right thigh. Imaging studies revealed an ossified mass extending from dermal layer of the subcutaneous tissue with no connection to the underlying deep fascia. An excisional biopsy was performed and proved to be a subdermal extraskeletal osteochondroma.

scholarly journals Ganglioneuroma mimicking adrenal tumor

2020 ◽  
Vol 7 (8) ◽  
pp. 2737
Author(s):  
Abhijeet A. Jain ◽  
Girish D. Bakhshi ◽  
Jessika Shah ◽  
Dinesh Pawar ◽  
Aditya B. Marathe ◽  
...  
Keyword(s):  
Adrenal Glands ◽  
Adrenal Tumor ◽  
Posterior Mediastinum ◽  
Benign Tumors ◽  
Neurogenic Tumors ◽  
Complete Surgical Resection ◽  
Retroperitoneal Tumors ◽  
Surgical Options ◽  
Slow Growing ◽  
Growing Mass

Ganglioneuromas arise from neural crest sympathogonia and are rare benign neurogenic tumors. The most common affected sites are posterior mediastinum and the retroperitoneum. They rarely affect adrenal glands. Ganglioneuromas often present as solitary, painless and slow growing mass and are benign in nature. These tumors are closely related to major vessels. Hence, surgical management of retroperitoneal pathologies may require multiorgan resection in order to achieve complete surgical resection while preservation of surrounding organs especially in case of benign tumors. We present a case report of a 21 year old male with a 12×10×10 cm size right sided retroperitoneal ganglioneuroma which on computed tomography (CT) mimicked adrenal tumor crossing the midline and abutting the aorta and splaying the inferior venal cava and renal vein. Present paper is an attempt to review the various surgical options available while dealing with these benign retroperitoneal tumors which are related closely to retroperitoneal organs and major vessels.

INTRAOSSEOUS ANGIOLIPOMA OF THE CRANIUM

Neurosurgery ◽  
2009 ◽  
Vol 64 (1) ◽  
pp. E189-E190 ◽  
Author(s):  
Kenny Yu ◽  
James Van Dellen ◽  
Philip Idaewor ◽  
Federico Roncaroli
Keyword(s):  
Clinical Presentation ◽  
Subcutaneous Tissue ◽  
Rare Condition ◽  
Surgical Excision ◽  
Benign Tumors ◽  
Complete Surgical Excision ◽  
History Of ◽  
Titanium Cranioplasty ◽  
Intraosseous Lesion ◽  
Slow Growing

Abstract OBJECTIVE We describe an intraosseous angiolipoma of the cranium and discuss the outcome. Angiolipomas are benign tumors that consist of mature adipose tissue and abnormal vessels. They occur predominantly in the subcutaneous tissue of the trunk and upper limbs. Only 4 examples of intraosseous angiolipomas have been reported in the literature, all of which involved the mandible and ribs. CLINICAL PRESENTATION A 39-year-old man presented with a right parietal swelling. The patient initially refused surgery; thus it was possible to follow this case for 11 years, allowing us to evaluate the natural history of this rare condition. INTERVENTION Complete surgical excision of the intraosseous lesion was achieved with a titanium cranioplasty performed at intervals. Fifteen months after surgery, no recurrence was seen. CONCLUSION This is the first known report of intraosseous angiolipoma of the cranium. Angiolipomas are rare, benign, slow-growing tumors with an excellent prognosis. On preoperative neuroimaging, they may mimic intraosseous angiomas, lipomas, or intraosseous meningiomas. Total resection is curative.

scholarly journals Scapular Osteochondroma: An Infrequent Case

2018 ◽  
Vol 3 (4) ◽  
pp. 1031-1034
Author(s):  
Luis Espín ◽  
Gabriela Espín ◽  
Richard Silva
Keyword(s):  
Bone Growth ◽  
Benign Tumor ◽  
Surgical Excision ◽  
Excisional Biopsy ◽  
Ventral Surface ◽  
Benign Tumors ◽  
Long Bones ◽  
Sarcomatous Change ◽  
Rare Benign Tumor ◽  
Mechanical Irritation

Osteochondroma of the scapula is a rare benign tumor in view of its location, which produces pain and mechanical dysfunction of the joint when it is on the ventral surface of the scapula, mainly affecting men during bone growth periods, between the ages of 10 and 30, accounting for 14.4 % of all scapula tumors and 49 % of benign tumors of the scapula. They arise in the metaphyseal regions of the long bones (femur, humerus, tibia), causing mechanical irritation leading to functional impotence, bursitis, and fracture of the scapula. Few cases in flat bones have been described. Diagnosis is made with physical, clinical and complementary examinations, and must be confirmed by prior histopathology biopsy. The surgical indication includes mechanical dysfunction of a joint or tendon in relation to the size of the lesion, sarcomatous change being the procedure of choice in open surgical excision. The case of an 11-year-old girl who was diagnosed with a subscapular osteochondroma after previous excisional biopsy, is described below.

CASE REPORT: LIPOSARCOMA WITH MICROVASCULAR PROLIFERATION IN A COCKATIEL (Nymphicus hollandicus)

2019 ◽  
Vol 45 (03) ◽  
pp. 85-89
Author(s):  
Jung-Chin Chang ◽  
Fang-Yi Tsai ◽  
Yu-Shing Lee ◽  
Ruo-Chan Wang ◽  
Ju-Pai Kao ◽  
...  
Keyword(s):  
Blood Vessels ◽  
Lipid Droplets ◽  
Excisional Biopsy ◽  
Positive Staining ◽  
Uropygial Gland ◽  
Microvascular Proliferation ◽  
Nymphicus Hollandicus ◽  
Well Differentiated ◽  
Oil Red O ◽  
Growing Mass

A five-year-old female cockatiel weighing 117 g was presented with a fast-growing mass beside the uropygial gland. Excisional biopsy was performed and the mass measured [Formula: see text][Formula: see text]cm in size and weighed 30.6 g. On the surface of cut sections, the mass was yellow-brown with white or yellow colloidal substances and red exudate. Histopathology showed that the tumor mass was covered by the skin and located in the deep dermis and hypodermis. The tumor consisted of abundant vascular adipose tissue and lipoblasts with intracytoplasmic lipid droplets, which varied in size. Also, small, well-differentiated blood vessels, with varied degrees of congestion and dilation, were observed within the tumor. Histochemically, staining with Oil red O produced a positive reaction in which the lipid droplets presented a reddish color. Immunohistochemistry produced positive staining for Desmin and successfully marked the muscular layers of blood vessels. On the basis of these results, a rare case of liposarcoma with microvascular proliferation adjacent to the uropygial gland was diagnosed in a cockatiel.

scholarly journals Giant Parotid Pleomorphic Adenoma with Atypical Histological Presentation and Long-Term Recurrence-Free Follow-Up after Surgery: A Case Report and Review of the Literature

2020 ◽  
Vol 2020 ◽  
pp. 1-18
Author(s):  
Mohammed AlKindi ◽  
Sundar Ramalingam ◽  
Lujain Abdulmajeed Hakeem ◽  
Manal A. AlSheddi
Keyword(s):  
Pleomorphic Adenoma ◽  
Surgical Management ◽  
Early Stage ◽  
English Literature ◽  
Benign Tumors ◽  
Adjuvant Radiation ◽  
Extracapsular Dissection ◽  
Slow Growing

Salivary gland tumors (SGT) comprise 3% of all head and neck tumors, are mostly benign, and arise frequently in the parotid gland. Pleomorphic adenoma (PA) is the commonest SGT, representing 60-70% of all benign parotid tumors. Clinically, parotid PA presents as irregular, lobulated, asymptomatic, slow-growing preauricular mass, involving both superficial and deep lobes, and could grow to gigantic proportions. Histologically, PA has epithelial and mesenchymal elements in chondromyxoid matrix and is managed surgically. Based on a review of 43 cases reported in English literature since 1995, giant parotid PA is reported as large as 35 cm (diameter) and 7.3 kg (resected weight). Although rare, 10 cases of malignant transformation were reported in the review. Surgical management included extracapsular dissection (ECD), superficial parotidectomy, and total parotidectomy for benign tumors, and adjuvant radiation or chemotherapy for malignant tumors. We further present the case of a 36-year-old healthy male with slow-growing and asymptomatic giant parotid PA, of 4-year duration. The patient presented with firm, lobulated preauricular swelling, provisionally diagnosed as PA based on radiographic and cytological findings. The tumor was resected through ECD, and the patient had uneventful postoperative recovery and a 7-year recurrence-free follow-up period. Histological examination revealed epimyoepithelial proliferation punctuated by chondromyxoid areas, with extensive squamous metaplasia and keratin cysts. To the best of knowledge from indexed literature, giant parotid PA is rarely reported in Saudi Arabia. In addition to its rarity, this case is reported for its benign nature despite atypical histological presentation, successful surgical management without complications, and long-term recurrence-free follow-up. Based on this report, clinicians must be aware of atypical histological presentations associated with PA and plan suitable surgical management and follow-up to avoid morbidity. Nevertheless, attempts must be made to diagnose and manage these lesions at an early stage and before they reach gigantic proportions.

scholarly journals Pyelonephritis can be a source of a life threatening necrotizing myofasciitis

2014 ◽  
Vol 8 (5-6) ◽  
pp. 462
Author(s):  
Haytham Kamel ◽  
Mohamed Soliman Edris Awed ◽  
Ahmed Fouad Kotb
Keyword(s):  
Necrotizing Fasciitis ◽  
Adult Male ◽  
Soft Tissues ◽  
Subcutaneous Tissue ◽  
Relevant Literature ◽  
Deep Fascia ◽  
Necrotizing Myositis ◽  
Life Threatening

Necrotizing fasciitis is a progressive, rapidly spreading, inflammatory infection located in deep fascia. It may cause necrosis of skin and subcutaneous tissue and can even result in involvement of adjacent soft tissues such as muscles resulting in necrotizing myositis. We report the case of an adult male presenting with necrotizing myofasciitis secondary to left pyelonephritis. We also review the relevant literature.

scholarly journals Diffuse neurofibroma - an uncommon cause of alopecia

2013 ◽  
Vol 88 (6 suppl 1) ◽  
pp. 166-169 ◽  
Author(s):  
Vasco Coelho Macias ◽  
Margarida Rafael ◽  
Cândida Fernandes ◽  
Joaninha Costa Rosa
Keyword(s):  
Young Adults ◽  
Subcutaneous Tissue ◽  
Neurofibromatosis Type ◽  
Benign Tumors ◽  
Nerve Sheath ◽  
Spindle Cells ◽  
Children And Young Adults ◽  
Low Incidence ◽  
Infiltrative Tumor

Although infrequent, alopecia can be caused by benign cutaneous tumours. Neurofibromas are common benign tumors that originate in the peripheral nerve sheath. Diffuse neurofibroma is a rare variant of neurofibroma that is thought to occur mainly in the head and neck of children and young adults. Histology generally shows an infiltrative tumor, composed of spindle cells in the dermis and subcutaneous tissue. Despite being rare, malignant transformation has been reported. The association between diffuse neurofibromas and neurofibromatosis type 1 still remains to be determined since some authors question the low incidence usually described. We report the case of a 42-year-old man who had a diffuse neurofibroma on the scalp presenting as alopecic plaques.

scholarly journals Adenomatoid Tumor of Testis

2009 ◽  
Vol 2 ◽  
pp. CPath.S3091 ◽  
Author(s):  
Waqas Amin ◽  
Anil V. Parwani
Keyword(s):  
Wilms Tumor ◽  
Frozen Section ◽  
Benign Tumors ◽  
Excision Biopsy ◽  
Clinical Consideration ◽  
Fibrous Stroma ◽  
Beta Hcg ◽  
Columnar Cells ◽  
Slow Growing ◽  
Vacuolated Cytoplasm

Adenomatoid tumors are responsible for 30% of all paratesticular masses. These are usually asymptomatic, slow growing masses. They are benign tumors comprising of cords and tubules of cuboidal to columnar cells with vacuolated cytoplasm and fibrous stroma. They are considered to be of mesothelial origin supported by histochemical studies and genetic analysis of Wilms tumor 1 gene expression. Excision biopsy is both diagnostic and therapeutic procedure. The main clinical consideration is accurate diagnosis preventing unnecessary orchiectomy. Diagnostic studies include serum tumor markers (negative alpha fetoprotein, beta HCG, LDH) ultrasonography (hypoechoic and homogenous appearance) and frozen section.

scholarly journals A rare clinical case: schwannoma of tongue

2019 ◽  
Vol 5 (3) ◽  
pp. 789
Author(s):  
Chandra Veer Singh ◽  
Sheetal Radia ◽  
Saalim Sheikh ◽  
Vijay Haribhakti
Keyword(s):  
Head And Neck ◽  
Rare Case ◽  
Neck Region ◽  
Surgical Excision ◽  
Imaging Studies ◽  
Head And Neck Tumours ◽  
Head And Neck Region ◽  
Complete Surgical Excision ◽  
Slow Growing ◽  
Rule Out

<p class="abstract">Schwannoma are slow growing tumours, which can arise from any peripheral nerve. 10% of schwannomas that occur in the head and neck region mostly originate from the vagus or sympathetic nervous system. Extracranial schwannomas in the head and neck region are rare neoplasm. Intraoral schwannoma are only 1% of the all head and neck tumours. Diagnosis is established by imaging studies such as magnetic resonance imaging or computed tomography, while FNAC is used to rule out other conditions. We report a rare case of lingual schwannomas generally present as a painless lump schwannoma of the tongue in a 27-year-old male complaining of asymptomatic swelling over a posterolateral surface of the tongue, treated by complete surgical excision. The diagnosis was established on the basis of clinical, histopathological, and immunohistochemical examination. We report a rare case of schwannoma over the posterolateral surface of tongue. Prognosis is good for the patient when this condition is correctly diagnosed as the condition rarely recurs after complete resection.</p>

scholarly journals Exposure to the RXR agonist SR11237 in early life causes disturbed skeletal morphogenesis in a rat model

2019 ◽  
Author(s):  
Holly Dupuis ◽  
Michael Andrew Pest ◽  
Ermina Hadzic ◽  
Thin Xuan Vo ◽  
Daniel B. Hardy ◽  
...  
Keyword(s):  
Growth Plate ◽  
Bone Growth ◽  
Long Bone ◽  
Tunel Staining ◽  
Long Bones ◽  
Micro Computed Tomography ◽  
Computed Tomography Scanning ◽  
Calcified Tissue ◽  
Trap Staining ◽  
Tomography Scanning

AbstractLongitudinal bone growth occurs through endochondral ossification (EO), controlled by various signaling molecules. Retinoid X Receptor (RXR) is a nuclear receptor with important roles in cell death, development, and metabolism. However, little is known about its role in EO. In this study, the agonist SR11237 was used to evaluate RXR activation on EO.Rats given SR11237 from post-natal day 5 to 15 were harvested for micro-computed tomography scanning and histology. In parallel, newborn CD1 mouse tibiae were cultured with increasing concentrations of SR11237 for histological and whole mount evaluation.RXR agonist-treated rats were smaller than controls, and developed dysmorphia of the growth plate. Cells invading the calcified and dysmorphic growth plate appeared pre-hypertrophic in size and shape corresponding with P57 immunostaining. Additionally, SOX9 positive cells were found surrounding the calcified tissue. The epiphysis of SR11237 treated bones showed increased TRAP staining, and additional TUNEL staining at the osteo-chondral junction. MicroCT revealed morphological disorganization in the long bones of treated animals. Isolated mouse long bones treated with SR11237 grew significantly less than their DMSO controls.This study demonstrates that stimulation of the RXR receptor causes irregular ossification, premature closure of the growth plate, and disrupted long bone growth in rodent models.

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