scholarly journals Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Samid M. Farooqui ◽  
Muhammad S. Khan ◽  
Laura Adhikari ◽  
Viral Doshi
Keyword(s):  
Granular Cell Tumor ◽  
Main Bronchus ◽  
Granular Cell ◽  
Middle Lobe ◽  
Cell Tumor ◽  
Diagnostic Challenge ◽  
Right Middle Lobe ◽  
The Right ◽  
Lost To Follow Up

Granular cell tumor (GCT) is a neoplasm of Schwann cell origin. Its presence in the aerodigestive tract is uncommon and becomes a diagnostic challenge on initial presentation. Our case is of a 59-year-old woman who presented to the emergency department with a history of productive cough and dyspnea associated with fever and chest pain. An initial chest X-ray (CXR) showed a right middle lobe consolidation with follow-up Computed Tomography (CT) scan showing a mass in the right bronchus. Bronchoscopy revealed a polypoid, sessile granular mass in the right bronchus intermedius with multiple white lesions in trachea, left main bronchus, and right upper bronchi. Histology revealed a benign GCT. Bronchoalveolar lavage from the right middle lobe grew Streptococcus pneumoniae. Patient was treated with intravenous levofloxacin during hospital stay and discharged on a 7-day course of oral antibiotics to be followed as outpatient but was lost to follow-up. GCT can present as a polypoid tumor causing recurrent postobstructive pneumonia. Surgical resection is the most successful treatment option. The tumor is more common in third and fourth decade of life and our patient is the oldest patient, according to our knowledge, to have a GCT.

scholarly journals A Malignant Granular Cell Tumor Excised with Mohs Micrographic Surgery

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
David Crowe ◽  
Elias E. Ayli ◽  
Hugh M. Gloster
Keyword(s):  
Metastatic Disease ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Mohs Micrographic Surgery ◽  
Micrographic Surgery ◽  
Diagnostic Challenge ◽  
Early Presentation ◽  
Malignant Granular Cell Tumor

Malignant granular cell tumors are extremely rare, aggressive neoplasms displaying rapid growth and frequent associated metastatic disease. Excision and evaluation for metastatic disease are mandatory. We present a 54-year-old patient with a malignant granular cell tumor, treated with Mohs micrographic surgery. Cutaneous granular cell tumors are uncommon neoplasms, likely of perineural origin. Most follow a benign and uneventful course, with wide local excision being the treatment of choice (Enzinger, 1988). The malignant granular cell tumor is an extremely rare, aggressive variant, which provides a diagnostic challenge and management dilemma, especially with early presentation when it may be mistaken for other entities. There is also controversy regarding surgical management and follow-up of both benign and malignant granular cell tumors.

scholarly journals Benign Endobronchial Granular Cell Tumor Resulting in Right Middle Lobe Collapse

2012 ◽  
Vol 25 (4) ◽  
pp. 365-366 ◽  
Author(s):  
Mehrzad Zarghouni ◽  
Thomas M. Seale ◽  
Emily Ogden ◽  
Clare M. Savage ◽  
Brett W. Carter
Keyword(s):  
Granular Cell Tumor ◽  
Granular Cell ◽  
Middle Lobe ◽  
Cell Tumor ◽  
Right Middle Lobe

scholarly journals Granular cell tumor of the breast: correlations between imaging and pathology findings

2020 ◽  
Vol 53 (2) ◽  
pp. 105-111
Author(s):  
Natacha Abreu ◽  
Juliana Filipe ◽  
Saudade André ◽  
José Carlos Marques
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Granular Cell Tumor ◽  
Kinetic Curve ◽  
Granular Cell ◽  
Cell Tumor ◽  
Imaging Features ◽  
Resonance Imaging ◽  
Diagnostic Challenge ◽  
Picture Archiving And Communication

Abstract Objective: To review the imaging features of granular cell tumors of the breast (on mammography, ultrasound, and magnetic resonance imaging), establishing a pathological correlation, in order to familiarize radiologists with this entity and make them aware of the differential diagnoses, other than malignancy, of lesions with spiculated margins. Materials and Methods: We reviewed the medical records (from a clinical-pathology database and picture archiving and communication system) of five patients with a pathologically confirmed diagnosis of granular cell tumor of the breast, treated at the Portuguese Oncology Institute of Lisbon, in the city of Lisbon, Portugal, between January 2012 and December 2018. Results: All five tumors exhibited imaging features highly suggestive of malignancy (BI-RADS 5 lesions), namely spiculated margins, significant depth, and posterior acoustic shadowing (on ultrasound). One tumor showed a kinetic curve indicative of washout on magnetic resonance imaging, two were adherent to the pectoralis muscle, and one was accompanied by skin retraction. Pathology provided the definitive diagnosis in all cases. Conclusion: Granular cell tumors of the breast pose a diagnostic challenge because they can present with clinical and imaging features mimicking malignancy, and the diagnosis is therefore provided by pathology. Radiologists should be familiarized with this entity, so they can be aware of the fact that breast lesions with spiculated margins can be indicative of diagnoses other than malignancy.

scholarly journals Metastasizing Malignant Granular Cell Tumor (Abrikossoff Tumor) of the Anterior Abdominal Wall, with Prolonged Survival

2019 ◽  
Vol 2019 ◽  
pp. 1-8
Author(s):  
Yara A. Alnashwan ◽  
Khaled A. H. Ali ◽  
Samir S. Amr
Keyword(s):  
Abdominal Wall ◽  
Poor Prognosis ◽  
Granular Cell Tumor ◽  
Anterior Abdominal Wall ◽  
Granular Cell ◽  
Cell Tumor ◽  
Prolonged Survival ◽  
Review Of The Literature ◽  
Malignant Granular Cell Tumor ◽  
The Right

Malignant granular cell tumor (MGCT) is a rare high-grade mesenchymal tumor of Schwann cell origin. MGCTs commonly affect thigh, extremity, and trunk; however, involvement of the abdominal wall is quite rare. It has poor prognosis with 39% mortality rate in 3-year interval. We report a 50-year-old female who had MGCT arising in the anterior abdominal wall and developed massive metastatic deposits in both lungs and in the right inguinal lymph nodes, with prolonged survival for 11 years. A brief review of the literature is presented.

scholarly journals Pazopanib monotherapy in a patient with a malignant granular cell tumor originating from the right orbit: A case report

2015 ◽  
Vol 10 (2) ◽  
pp. 972-974 ◽  
Author(s):  
SACHI MORITA ◽  
MARIKO HIRAMATSU ◽  
MIHOKO SUGISHITA ◽  
BISHAL GYAWALI ◽  
TAKASHI SHIBATA ◽  
...  
Keyword(s):  
Case Report ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Malignant Granular Cell Tumor ◽  
The Right

Benign Granular Cell Tumors of the Larynx: A Review of 36 Cases with Clinicopathologic Data

1975 ◽  
Vol 84 (3) ◽  
pp. 308-314 ◽  
Author(s):  
John Compagno ◽  
Vincent J. Hyams ◽  
Pierre Ste-Marie
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Vocal Cord ◽  
Granular Cell Tumor ◽  
Squamous Epithelium ◽  
Granular Cell ◽  
Cell Tumor ◽  
Clinical Impression ◽  
True Vocal Cord

The clinical, microscopic, and gross features of 36 cases of benign granular cell tumor arising in the larynx are reviewed and studied. This infrequent lesion, when in the larynx, is found most commonly on the true vocal cord in adults in their third, fourth, and fifth decades; there is no obvious sex predilection. Slowly increasing hoarseness was the primary complaint in our cases. Clinically, the tumors are considered benign. The most common clinical impression was a vocal cord papilloma. The microscopic pattern of the granular cell tumors is uniform and bland, but there may be a marked pseudoepitheliomatous hyperplasia of the overlying squamous epithelium, often stimulating squamous cell carcinoma. Follow-up information is discussed, as is the origin and histogenesis of this lesion.

scholarly journals Fatal congenital lobar emphysema in a puerpera: a case report and literature review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fanyi Gan ◽  
Liang Xia ◽  
Yushang Yang ◽  
Qiang Pu ◽  
Lunxu Liu
Keyword(s):  
Left Lung ◽  
Middle Lobe ◽  
Left Hemithorax ◽  
Recurrent Pneumonia ◽  
Mediastinal Shift ◽  
Life Threatening ◽  
Right Middle Lobe ◽  
Lobar Emphysema ◽  
The Right

Abstract Background Congenital lobal emphysema (CLE) is a developmental lung abnormality usually diagnosed in the neonatal period and is rarely observed in adults. Adults with CLE are usually asymptomatic and only a small fraction may present with coughing, recurrent pneumonia and respiratory distress. In imaging studies, the most frequently affected lobe of CLE is the left upper lobe, followed by the right middle lobe. However, multilobar involvement with severe mediastinal shift is extremely rare. Case presentation We report a case of fatal CLE in a 28-year-old puerpera with postpartum respiratory failure. Chest computed tomography (CT) revealed emphysema of the right upper, middle and lower lobes resulting in adjacent atelectasis. Hyperinflation of the right upper lobe crossed the midline, leading to a deviation of the mediastinal structure to the left hemithorax and severe compression of the left lung. Conclusions Early and timely diagnosis of CLE with routine follow-up is necessary for patients. CLE, especially with multilobar involvement or mediastinal shift, could be life-threatening and should be promptly and aggressively treated to prevent severe complications.

scholarly journals Granular Cell Tumor of the Tongue: A Rare Case Presentation of a 14 Years Old Girl

2021 ◽  
pp. 1-2
Author(s):  
Mansour Nacouzi ◽  
Keyword(s):  
Granular Cell Tumor ◽  
Benign Neoplasm ◽  
Granular Cell ◽  
Cell Tumor ◽  
Lateral Border ◽  
Case Presentation ◽  
Granular Cytoplasm ◽  
The Right ◽  
Sixth Decade ◽  
Mobile Tongue

Granular cell tumor or Abrikossoff ’s tumor is an infrequent tumor that can arise in most organs, and especially in the ENT area. It is a usually benign neoplasm, that can lead to a misdiagnose of malignancy. It affects both sex, between the fourth and the sixth decade. We present in this report a case of a 14 years old girl with a slowly growing lesion on the right lateral border of the mobile tongue. The biopsy showed a proliferation of large cells with a granular cytoplasm that expressed two immunohistochemistry markers: CD68 and S100 antibodies. Surgical resection was completed with a one centimeter margin.The rare issue about this case is the age of presentation: the age of the patient is 14, whereas this tumor usually affects adult patients.

scholarly journals A granular cell tumor arising from the trachea and extending into the left main bronchus

2008 ◽  
Vol 22 (7) ◽  
pp. 1088-1093
Author(s):  
Shigeru Nakane ◽  
Akinori Akashi ◽  
Kenjiro Fukuhara ◽  
Emiko Tomita
Keyword(s):  
Granular Cell Tumor ◽  
Main Bronchus ◽  
Granular Cell ◽  
Left Main Bronchus ◽  
Cell Tumor ◽  
Left Main
Sign in / Sign up

Export Citation Format

Share Document