scholarly journals Mesenchymal Hamartoma of the Liver: Complete Excision Always Necessary

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Suman B. Koganti ◽  
Venu Madhav Thumma ◽  
Bheerappa Nagari

Mesenchymal hamartoma (MH) is not an uncommon tumor of the liver in the age group of 2–10 years. It is the second most common benign liver tumor in children. Previously considered a developmental anomaly, newer insights into other theories of origin including toxic-metabolic, ischemic, and a true neoplastic process are in progress. Previous understanding of a purely benign nature of the tumor is being overridden by a real malignant transformation. Complete excision of the tumor with clear margins is recommended to achieve a long term cure. A thorough understanding of the natural history of these tumors and skillful surgical treatment are indispensable elements of care.

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Gupta Rohit ◽  
Chinniahnapalaya Pandurangaiah Hariprasad ◽  
Shreekant Bharti ◽  
Anil Kumar ◽  
Shiv Shankar Paswan ◽  
...  

Background. Fibro lipoma of the spermatic cord is a very rare tumor with few cases reported in literature. Atypical presentation and site of swelling mystifies the diagnosis and creates bewildering situation intraoperatively. Case Summary. A 30-year-old farmer presented with an elastic firm nonreducible, nontender swelling at inguinoscrotal region with positive cough impulse and history of laparoscopic inguinal hernia repair 3 years ago. Ultrasonography of the swelling revealed a heteroechoic lesion of size 7 × 6 centimeter with probable features of lipoma or desmoid. Fine needle aspiration drawn in consideration of the diagnostic dilemma reported a benign lipomatous swelling which on final histopathology turned out to be a fibro lipoma of size 7 × 6 × 5  cm. Conclusion. Considering the age and presentation of the patient, it was astonishing. It provided an insight to the occurrence of fibro lipoma even in younger age group which in fact is the first case of its kind as per best of our knowledge. Malignancy should be ruled out in such cases, and complete excision is the treatment of choice.


Pelvic inflammatory disease (PID) is inflammation of the female upper genital tract—endometrium, fallopian tubes, ovaries, and supporting structures. Annual incidence is estimated at 1/1000 women, most common in the 15–24 age group. It is usually sexually acquired, commonly caused by C. trachomatis, N. gonorrhoeae, M. genitalium, and organisms associated with bacterial vaginosis. Risk factors include recent new sexual partner or multiple partners, and a past history of a sexually transmitted infection. Long-term sequelae include infertility and chronic pelvic pain. A diagnosis of PID is usually based on signs, symptoms, and examination. This chapter describes aetiology, diagnosis, and management of pelvic inflammatory disease.


2011 ◽  
Vol 47 ◽  
pp. 248-257
Author(s):  
Oliver Logan

Luigi (Alvise) Gonzaga (1568–91), heir to the principality of Castiglione delle Stiviere, renounced his succession in 1585 to enter the Jesuit novitiate, in the course of which he died of plague, evidently contracted while ministering to the sick. He was beatified with extraordinary rapidity in 1605, four years before Ignatius Loyola and Francis Xavier. Admittedly the figure of the ‘angelic youth’ Luigi, as presented in the life written by the promoter of the cause for his canonization, Virgilio Cepari, and finally published in 1606, was more conventional and more calculated to seize the popular imagination than the uncharismatic Loyola, who enjoyed a very limited cult initially and was slow to deliver miracles. But, more significantly, the beatification was a matter of dynastic politics: it was promoted not only by the Jesuits but also, and more insistently, by the Gonzaga dynasty, supported by the Holy Roman Emperor and by allied dynasties. A phase of bureaucratization of canonization processes, already under way, was intensified shortly after Luigi’s beatification. Moreover, the criteria for sainthood would seem to have shifted somewhat in the first half of the seventeenth century. Luigi was not canonized until 1726, under Benedict XIII. In 1729 the same pope pronounced him the patron of students in Jesuit educational institutions and apparently also of students more generally. This provided the basis for the cult of Luigi in the nineteenth century as the patron of ‘Catholic youth’, that is both adolescents and young adults. This development was linked to a novel understanding of adolescence as a specific age group and also to the Church’s battle against secularism. Thus the cult acquired a new relevance long after the princely world that had pressured for Luigi’s canonization had passed away. The legal history of canonization processes substantially explains the delay in Luigi’s canonization, but this delay is also partly explicable by the very complexity and ambiguity of Luigi’s image as both child and man, which served in the long term to give ever new life to his cult.


2020 ◽  
Vol 16 (1) ◽  
Author(s):  
Moaied A. Hassan

Abstract Background Mesenchymal hamartoma is the second most common benign liver tumor in children, with 20% of the cases diagnosed during the neonatal period. The exact etiology in still unclear, and most investigators believe that it is a developmental anomaly rather than a true neoplasm. The presentation of these tumors is highly variable depending on the lesion’s size, ranging from small asymptomatic lesions to very large tumors with life threatening complications. Radical surgical excision, whenever possible, is the gold standard for treating these lesions to avoid the problems of local recurrence and possible malignant transformation. We present the rare occurrence of an entirely solid, giant hepatic mesenchymal hamartoma in a 3-week-old male newborn and discuss the mode of presentation, as well as the diagnostic and therapeutic approach. Case presentation A 3-week-old male newborn was referred to our institution with huge abdominal distension and respiratory distress. Imaging studies confirmed the presence of a very large solid intraabdominal mass occupying the majority of the abdominal cavity and abutting the inferior aspect of the right lobe of the liver, but did not reveal the diagnosis. At laparotomy, a huge solid mass was found attached to the right lobe of the liver. Complete excision was done, and histopathological examination confirmed the diagnosis of mesenchymal hamartoma. Conclusion Although rare, mesenchymal hamartoma of the liver can present as a neonatal surgical emergency. Emergency intervention is required in symptomatic patients. Radical surgical intervention is possible and is the treatment of choice to relieve the patient’s symptoms and avoid future complications.


2017 ◽  
Vol 37 (1) ◽  
pp. 86-88
Author(s):  
Rajesh Prasad Sah ◽  
R.G. Sah ◽  
Shaukat Mahmood

A 10 year boy presented with history of abdominal pain and palpitation. Abdominal ultrasound and CT oriented towards the diagnosis. After preoperative optimization, laparotomy with complete excision of an unusual pheochromocytoma tumour of about 8×10 cm adherent to liver and IVC performed. Histopathology confirmed the diagnosis without evidence of malignancy.


2020 ◽  
Vol 22 (Supplement_I) ◽  
pp. I38-I42
Author(s):  
Elaine M Hylek

Abstract Older adults with atrial fibrillation are at the highest risk of ischaemic stroke yet are the least likely to be prescribed anticoagulant therapy, adhere to this therapy, and maintain long-term persistence with this therapy. The reasons for this under treatment are multifactorial and include patient-driven factors, physician-driven factors, medical system complexities, and current unknowns regarding the biology and natural history of AF. Understanding these challenges to stroke prevention and addressing identified barriers to medication adherence and persistence in this vulnerable age group will improve outcomes related to AF.


2021 ◽  
Author(s):  
Tianming Yang ◽  
Lin Xiao ◽  
Huijun Ren

Abstract Liposarcoma is common in adults; however, it very rarely occurs in the retropharyngeal space, and to date, no cases of liposarcoma in the prevertebral space have been reported. A 78-year-old man presented at the Otolaryngology Department with a 1-month history of dyspnea and dysphonia. Magnetic resonance imaging of the neck reveled a retropharyngeal mass extending from the superior margin of the axis to the level of the 7thcervical vertebra. A computed tomography scan of the patient’s neck uncovered the relationship between the mass and its’ surrounding structures. Based on the above examinations, a diagnosis of retropharyngeal liposarcoma was made initially. The patient underwent transoral surgical excision with the assistance of a nasal endoscope. During surgery, the tumor was located in the prevertebral space. Combined with pathology and immunohistochemistry examinations, the diagnosis was modified to well-differentiated liposarcoma of the prevertebral space. At the 1-year follow-up, the patient was well and there was no evidence of recurrence. The long-term outcomes are not yet known. Liposarcoma of the prevertebral space may sometimes be misdiagnosed as retropharyngeal liposarcoma; however, in our view, it is not necessary to focus on differentiating between enormous retropharyngeal and prevertebral tumors. In relation to the short-term outcome, complete excision using the transoral approach with the aid of nasal endoscope may present a better choice than the cervical approach in treating these tumors, especially in old people.


2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Holger Sudhoff ◽  
Randolf Klingebiel ◽  
Lars-Uwe Scholtz ◽  
Ingo Todt

Objective. To introduce a novel surgical approach to petrous apex lesion (PA) with superior semicircular canal plugging for hearing preservation. Patient. A 63-year-old patient presented with a recurrent cholesteatoma of the left petrous apex. The patient had a long-term history of cholesteatoma and MRI with diffusion-weighted imaging (DWI) detected a suspicious lesion in the left petrous apex on follow-up. Intervention. The cholesteatoma could be completely removed from the petrous apex with partial superior semicircular canal plugging and removal with hearing preservation. Outcomes. Cholesteatomas of the temporal bone are managed by surgery with complete excision of the lesion. Results. The translabyrinthine approach, generally useful in nonhearing ears, could be utilized with the additional technique of superior semicircular canal plugging to preserve hearing in this patient. Conclusions. This case highlights the possibility of a hearing preservation strategy for PA cholesteatomas using a translabyrithine approach.


2017 ◽  
Vol 3 (2) ◽  
pp. 205511691774252 ◽  
Author(s):  
Laura Bataller ◽  
Alice Tamborini ◽  
Henry L’Eplattenier ◽  
Slavka Necova ◽  
Elise Robertson

Case summary An 8-year-old female spayed Siamese indoor cat presented with a 3 week history of inspiratory dyspnoea, stridor and open-mouth breathing after exercise. Laryngoscopy, tracheoscopy, bronchoscopy and retroflexed nasopharyngoscopy were performed, and identified a multilobulated intraluminal mass within the trachea. Brush cytology was performed on the mass but was inconclusive in providing a definitive diagnosis. A CT scan of the neck failed to identify an obvious intraluminal mass and was negative to contrast uptake. Surgery was performed and seven rings of the trachea were removed to enable the complete excision of the mass. Histopathology of the excised mass was consistent with B cell lymphoma. After surgery, chemotherapy treatment was started. At the time of writing, 20 months since diagnosis, the cat remained clinically well, with no clinical signs or recurrence of macroscopic disease on endoscopic evaluation. Relevance and novel information Upper airway endoscopy was considered to be an essential diagnostic tool in this case presenting with signs of upper respiratory dyspnoea. Moreover, combined surgery and chemotherapy were considered effective treatments and positively affected the long-term prognosis of this patient.


Author(s):  
Sunny Agarwal ◽  
Suresh B. ◽  
Mathew Varghese ◽  
Vishesh Khanna ◽  
Mandeep Singh Bajaj

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Long term results of tenotomy and Ponseti technique are established worldwide. However, functions of Tendoachilles following Ponseti’s tenotomy in these cases i.e. idiopathic/neglected/operated/relapsed clubfeet (after casting or surgical correction) are not established. Tendoachilles regeneration after tenotomy has been confirmed on USG and MRI but only a few studies have done functional evaluation of tendoachilles<strong>.</strong> This study was done to evaluate the functional outcome of tendoachilles after tenotomy in patients older than two years presenting with CTEV. This study also assessed the influence of age and any previous treatment on tenotomy.</span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">In this study, 42 children (68 clubfeet) were seen in the two year study period. Children between 2-13 years coming to the outpatient department for treatment using the Ponseti’s method were followed during and after completion of treatment for 2 years. Patients were divided into two groups-first according to age and second according to previous treatment. Clinical evaluation of tendoachilles regeneration was done by evaluating the child’s ability to stand on tip of toes on single leg and walking ability</span>.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">The ability to stand on tip of toes after removal of the final cast was delayed maximum in the previously operated patients (9.5 weeks), lesser in patients who were previously treated by casting (7.3 weeks) and least in neglected patients (7 weeks). It also increased as the age increased (2-5 years age group required 7.4 weeks whereas 11-13 years age group required 16 weeks). Neglected patients started walking earlier (4.6 weeks) as compared to patients treated conservatively (4.8 weeks) or operatively (7.2 weeks). Younger children started walking earlier (age 2-5 years required 4.7 weeks whereas 11-13 years age group required 12 weeks). </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Functional evaluation of tendoachilles showed that all children who had tenotomy could walk and stand on tip of toes irrespective of age and previous treatment. However, older child and children having history of previous treatment, required longer time for recovery.</span></p>


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