scholarly journals Mycoplasma Pneumonia: An Unrecognized Cause of Fever of Unknown Origin in an Adult

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Fatima Ali-Ahmed ◽  
Alexandra Halalau
Keyword(s):  
Fever Of Unknown Origin ◽  
Unknown Origin ◽  
Source Of Infection ◽  
Left Ankle ◽  
Pulmonary Manifestations ◽  
Mycoplasma Pneumonia ◽  
History Of ◽  
Hilar Adenopathy ◽  
Chest X Ray ◽  
Tomography Scan

A 26-year-old female was admitted for fever of unknown origin (FUO), headaches, left ankle edema, and a lower extremity rash consistent with erythema nodosum. She had no respiratory symptoms or family history of autoimmune diseases. A chest X-ray was negative for pneumonia or hilar adenopathy. Extensive autoimmune workup was negative. A chest, abdomen, and pelvis computed tomography scan was unremarkable and laboratory studies revealed no source of infection. On hospital day 5, the patient developed a mild productive cough. Her Mycoplasma pneumonia (MP) IgM was high, confirming the diagnosis of MP induced FUO. She was started on azithromycin 500 mg daily and within 24 hours her fevers and headaches resolved. Her left ankle edema and EN gradually improved over a course of a few weeks. This case report highlights the need for MP testing in the evaluation of fever of unknown origin, even in the absence of pulmonary manifestations.

scholarly journals Pyrexia of unknown origin associated with a non-infected vaginal shelf pessary

2020 ◽  
Vol 49 (6) ◽  
pp. 1110-1111
Author(s):  
Mathew Gilbert ◽  
Myra Laurenson ◽  
James Casson ◽  
Ali Alsawaf
Keyword(s):  
Unknown Origin ◽  
Additional Line ◽  
Pyrexia Of Unknown Origin ◽  
Reactive Protein ◽  
Source Of Infection ◽  
Vaginal Pessary ◽  
Intravenous Antibiotics ◽  
Chest X Ray ◽  
Urine Microscopy ◽  
Tomography Scan

Abstract An 82-year-old female was admitted with pyrexia and rigors. Bloods showed a raised C-reactive protein and she was commenced on empirical intravenous antibiotics. Chest X-ray, urine microscopy and computed tomography scan of the patient’s abdomen and pelvis did not demonstrate a source of infection, and blood cultures did not grow a microorganism. A collateral history was taken from the patient’s husband who raised concerns regarding her vaginal shelf pessary and it was therefore removed. Subsequently the patient’s fever subsided, her inflammatory markers improved and she was discharged 2 days later. We believe this is the first reported case of pyrexia secondary to a non-infected vaginal pessary, and may provide clinicians with an additional line of enquiry when presented with patients with pyrexia of unknown origin.

scholarly journals Isolated tuberculosis of the spleen presenting with fever of unknown origin in a vaccinated child

2020 ◽  
Vol 2020 (10) ◽  
Author(s):  
Ameer Kakaje ◽  
Yousef Mahmoud ◽  
Osama Hosam Aldeen ◽  
Othman Hamdan
Keyword(s):  
Rare Case ◽  
Causes Of Death ◽  
Fever Of Unknown Origin ◽  
Unknown Origin ◽  
Bacillus Calmette Guerin ◽  
Immunocompetent Child ◽  
Mild Anaemia ◽  
History Of ◽  
Unnecessary Procedures ◽  
Immunocompromised Status

Abstract Tuberculosis (TB) is one of the top 10 causes of death worldwide and is more common in developing countries. Isolated splenic TB is typically found in trauma, miliary TB and immunocompromised status. We present a very rare case of an immunocompetent child with an isolated primary TB in the spleen. The child only had fever of unknown origin (FUO), and mild anaemia. The diagnosis was not made until splenectomy was performed. The patient took the quadruple therapy for TB, and follow-ups showed no recurrence. This case is unique because this child was immunocompetent with no history of trauma or active TB. TB diagnosis should never be ignored in FUO as this might prevent unnecessary procedures to the patient. Although the child was vaccinated with Bacillus Calmette–Guérin that usually protects against severe TB in first 5 years of life, it did not prevent from affecting the spleen.

scholarly journals A rare cause of wheezing

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Alexander H. Cho ◽  
Jessica Logan ◽  
Jalil Ahari
Keyword(s):  
Granular Cell ◽  
African American Female ◽  
Lobe Bronchus ◽  
Submucosal Tumors ◽  
Sputum Production ◽  
Endobronchial Lesion ◽  
History Of ◽  
Chest X Ray ◽  
The Right ◽  
Tomography Scan

A 24-year-old African American female nonsmoker, with a reported history of asthma presented to the hospital with 2 weeks of shortness of breath and sputum production. She had a chest X-ray and computed tomography scan that displayed evidence of a right upper lobe collapse. She subsequently had a bronchoscopy that revealed an endobronchial lesion at the opening of the right upper lobe bronchus. Biopsies performed were consistent with a granular cell tumor. Granular cell tumors are rare submucosal tumors of Schwann cell origin. Resection of the right upper lobe resolved her symptoms and wheezing.

scholarly journals Recurrent spontaneous pneumothoraces and vaping in an 18-year-old man: a case report and review of the literature

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Alex Bonilla ◽  
Alexander J. Blair ◽  
Suliman M. Alamro ◽  
Rebecca A. Ward ◽  
Michael B. Feldman ◽  
...  
Keyword(s):  
Spontaneous Pneumothorax ◽  
Electronic Cigarettes ◽  
Diagnostic Testing ◽  
Cigarette Use ◽  
Case Presentation ◽  
X Ray ◽  
History Of ◽  
Chest X Ray ◽  
Tomography Scan

Abstract Background Primary spontaneous pneumothorax is a common disorder occurring in young adults without underlying lung disease. Although tobacco smoking is a well-documented risk factor for spontaneous pneumothorax, an association between electronic cigarette use (that is, vaping) and spontaneous pneumothorax has not been noted. We report a case of spontaneous pneumothoraces correlated with vaping. Case presentation An 18-year-old Caucasian man presented twice with recurrent right-sided spontaneous pneumothoraces within 2 weeks. He reported a history of vaping just prior to both episodes. Diagnostic testing was notable for a right-sided spontaneous pneumothorax on chest X-ray and computed tomography scan. His symptoms improved following insertion of a chest tube and drainage of air on each occasion. In the 2-week follow-up visit for the recurrent episode, he was asymptomatic and reported that he was no longer using electronic cigarettes. Conclusions Providers and patients should be aware of the potential risk of spontaneous pneumothorax associated with electronic cigarettes.

scholarly journals Digital Clubbing and Hodgkin Disease in Children: A Case Report and Review of Literature

2021 ◽  
Vol 9 (3) ◽  
pp. 239-246
Author(s):  
Hossein Karami ◽  
◽  
Amir Mohammad Beyzaee ◽  
Farzad Masiha ◽  
Maryam Ghasemi ◽  
...  
Keyword(s):  
Mediastinal Lymph Node ◽  
Lymph Node Biopsy ◽  
Hodgkin Disease ◽  
Hypertrophic Osteoarthropathy ◽  
Case Presentation ◽  
Digital Clubbing ◽  
Night Sweats ◽  
History Of ◽  
Chest X Ray ◽  
Tomography Scan

Introduction: Digital clubbing (hypertrophic osteoarthropathy) as the initial presentation of lymphoma is rarely reported, particularly in children. In this study, we report a patient with intrathoracic Hodgkin Disease (HD) and digital clubbing as the first presentation, and we will review the literature regarding the same condition. Case Presentation: A 10-year-old boy presented with a 2-month history of cough, mild dyspnea, and night sweats, with prominent digital clubbing. A chest x-ray and a computed tomography scan of the chest showed multiple mediastinal masses. A mediastinal lymph node biopsy was done. Pathologic examination was indicative of nodular sclerosis HD. Conclusions: In patients with digital clubbing, intrathoracic malignancies should be considered a differential diagnosis and must be ruled out by precise examination and paraclinical help.

Liver Abscess in Normal Children With Fever of Unknown Origin

PEDIATRICS ◽  
1978 ◽  
Vol 61 (1) ◽  
pp. 148-148
Author(s):  
Henry H. Balfour
Keyword(s):  
Fever Of Unknown Origin ◽  
Unknown Origin ◽  
Blood Cultures ◽  
Abscess Drainage ◽  
Normal Children ◽  
Liver Abscesses ◽  
History Of ◽  
Liver Scan ◽  
And Staphylococcus Aureus ◽  
Normal Immune Function

The article by Kaplan and Feigin (Pediatrics 58:614, October 1976) is a useful reminder that pyogenic liver abscesses do occur in children with normal immune function, and should be included in the differential diagnosis of fever of unknown origin. In both of their patients there was no history of abdominal trauma, blood cultures were sterile, the clinical diagnosis was confirmed by liver scan, and Staphylococcus aureus organisms were isolated from the abscess drainage at surgery.

Arenaviruses

2020 ◽  
pp. 862-870
Author(s):  
Jan H. ter Meulen
Keyword(s):  
Fever Of Unknown Origin ◽  
Rna Viruses ◽  
Unknown Origin ◽  
Dust Particles ◽  
Rodent Control ◽  
Highly Pathogenic ◽  
Life Saving ◽  
History Of ◽  
Endemic Areas

Arenaviruses are zoonotic RNA viruses that are distributed worldwide and are adapted to various rodent genera. Some are highly pathogenic and cause haemorrhagic fevers that are endemic in restricted regions of a few countries. Humans are thought to become infected mainly through inhalation of aerosolized rodent urine or dust particles to which infectious urine has dried, or by ingestion of contaminated foodstuff: prevention therefore depends on rodent control and avoidance of contact with rodents, their excreta, and nesting materials. Because arenaviruses cause diseases that start insidiously and therapy is life-saving, they should be considered in all patients with fever of unknown origin and a history of possible exposure in the well-known endemic areas.

scholarly journals Current antimicrobial practice in febrile neutropenia across Europe and Asia: the EBMT Infectious Disease Working Party survey

2020 ◽  
Vol 55 (8) ◽  
pp. 1588-1594 ◽  
Author(s):  
Anke Verlinden ◽  
◽  
Malgorzata Mikulska ◽  
Nina Simone Knelange ◽  
Dina Averbuch ◽  
...  
Keyword(s):  
Combination Therapy ◽  
Febrile Neutropenia ◽  
Fever Of Unknown Origin ◽  
Working Party ◽  
Empirical Therapy ◽  
Unknown Origin ◽  
First Line ◽  
Neutrophil Recovery ◽  
History Of ◽  
Key Aspects

Abstract The aim of this survey was to summarize the current antimicrobial practice in febrile neutropenia and the presence of key aspects of antimicrobial stewardship. A questionnaire was sent to 567 centers, and complete responses were obtained from 194 (34.2%). Fluoroquinolone and co-trimoxazole prophylaxis are used in 57.1% and 89.1%, respectively. In 66.4%, the first-line empirical therapy is piperacillin/tazobactam, whereas 10.9% use carbapenems. Empirical combination therapy is used in stable patients without history of resistant pathogens in 37.4%. De-escalation to monotherapy is performed within 3 days in 35.3% and after 10 days in 19.1%. Empirical addition of a glycopeptide is performed when fever persists more than 2–3 days in 60.8%. Empirical escalation to a broader spectrum agent is performed when fever persists more than 3–5 days in 71.4%. In case of positive blood cultures with a susceptible pathogen and uncomplicated presentation, 76.7% of centers de-escalate and 36.6% discontinue before neutrophil recovery. In fever of unknown origin with uncomplicated presentation, 54.1% of centers de-escalate and 49.5% discontinue before neutrophil recovery. Recommendations put forward in the ECIL guidelines are not widely implemented in clinical practice. Specific problems include overuse of carbapenems and combination therapy and unjustified addition of glycopeptides without further de-escalation or discontinuation.

Sign in / Sign up

Export Citation Format

Share Document