scholarly journals Asynchronous Bilateral Ovarian Torsion: Three Cases, Three Lessons

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
M. C. Lucchetti ◽  
C. Orazi ◽  
A. Lais ◽  
M. L. Capitanucci ◽  
P. Caione ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Surgical Intervention ◽  
Case Reports ◽  
Young Patients ◽  
Clinical History ◽  
Ovarian Torsion ◽  
Review Of The Literature ◽  
Study Objective ◽  
Future Fertility ◽  
History Of

Background. Ovarian torsion (OT) is a serious condition, and delay in surgical intervention may result in loss of the ovary. Children and adolescents who have suffered from ovarian torsion may be at risk for asynchronous torsion of the contralateral ovary. Study objective. Three cases of asynchronous bilateral ovarian torsion were reported to analyse clinical history of three patients, to review the current literature, and to draw a conclusion for future treatment. Design. Case reports and review of the literature. Result. When a prepubertal girl presents with an ovarian torsion, several considerations have to be taken in account in order to preserve her future fertility; in particular, the pediatric surgeon/gynecologist has to preserve as much as possible the twisted ovary in addition to considering the fate of the contralateral ovary. Summary and Conclusions. Pelvic pain in a young girl has always raised the clinical suspect of an ovarian torsion; the possibility of asynchronous bilateral ovarian torsion is rare, but it is described in the literature and has catastrophic consequences; this condition has to be known and treated in the proper way by pediatric surgeons as well as by gynecologists in order to maximize the future fertility of the young patients.

scholarly journals Late Recurrence in Ovarian Dysgerminoma Presenting as a Primary Retroperitoneal Tumor: A Case Report and Review of the Literature

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Yuichiro Sato ◽  
Tohru Hayashi ◽  
Hidetaka Yamamoto ◽  
Ichiro Niina ◽  
Naoya Kuroki ◽  
...  
Keyword(s):  
Clinical History ◽  
Late Recurrence ◽  
Retroperitoneal Tumor ◽  
Retroperitoneal Mass ◽  
Review Of The Literature ◽  
Rare Type ◽  
History Of ◽  
Node Metastases ◽  
Ovarian Dysgerminoma ◽  
Primary Retroperitoneal

Ovarian dysgerminoma is a rare type of germ cell tumor. The majority of patient relapses occur within 2 years of diagnosis. Here, we report the case of a 74-year-old woman with a history of ovarian dysgerminoma 39 years earlier. The patient visited the hospital presenting with heartburn. An abdominal computed tomography (CT) revealed a right retroperitoneal mass, and a primary retroperitoneal tumor was suspected. She underwent surgical resection of the retroperitoneal tumor. Histological examination confirmed a metastatic dysgerminoma to the retroperitoneum. Postoperative CT showed paraaortic and cervical lymph node metastases. The patient was treated with bleomycin, etoposide, and cisplatin chemotherapy. This case demonstrates the difficulties that may be encountered in the differential diagnosis of a retroperitoneal mass and underlines the necessity for understanding a patient’s clinical history.

scholarly journals Idiopathic Granulomatous Mastitis Presenting as a Breast Pseudotumor: Case Reports with Review of the Literature

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Nour Abdul Halim ◽  
Imad Uthman ◽  
Rayan Rammal ◽  
Hazem I. Assi
Keyword(s):  
Clinical Presentation ◽  
Case Reports ◽  
Radiographic Finding ◽  
Breast Disease ◽  
Granulomatous Mastitis ◽  
Women Of Childbearing Age ◽  
Review Of The Literature ◽  
Childbearing Age ◽  
Idiopathic Granulomatous Mastitis ◽  
History Of

Idiopathic granulomatous mastitis is a rare benign inflammatory breast disease that affects women of childbearing age with a history of breastfeeding. It usually presents as an enlarging breast mass that can greatly mimic breast cancer. Moreover, it does not have a specific radiographic finding, so the only way to reach a definitive diagnosis is by core biopsy and histology. Furthermore, a consensus regarding the best treatment modality has not been reached yet. In this report, we describe the cases of two patients who suffered from this disease, and to our knowledge, such a report is the first of its kind to address this topic in this region. Therefore, because of its uncommon nature and obscure presentation, we hereby report two cases of idiopathic granulomatous mastitis. The clinical presentation, treatment, and pathological findings are described, and a literature review on idiopathic granulomatous mastitis will be reported.

scholarly journals Metastatic Pancreatic Cancer with BRAF and P53 Mutations: Case Report of Therapeutic Response to Doublet Targeted Therapy

2020 ◽  
Vol 13 (3) ◽  
pp. 1239-1243
Author(s):  
Shenthol Sasankan ◽  
Lorraine Rebuck ◽  
Gloria Darrah ◽  
Moises Harari Turquie ◽  
Ian Rabinowitz
Keyword(s):  
Pancreatic Cancer ◽  
Case Report ◽  
Targeted Therapy ◽  
Therapeutic Response ◽  
Case Reports ◽  
Clinical History ◽  
P53 Mutation ◽  
Metastatic Pancreatic Cancer ◽  
First Case ◽  
History Of

We report on the clinical history of a 49-year-old female with metastatic pancreatic cancer. She was initially treated with standard chemotherapy as per current guidelines. She was found to have both a BRAF and P53 mutation, and received dabrafenib and trametinib with deep responses, both radiographically and biochemically (CA19-9). Her response has been more clinically relevant than responses in previous case reports of patients with BRAF-positive pancreatic cancer treated with targeted therapy. To the best of our knowledge, this is the first case report showing a dramatic therapeutic response to combination therapy with dabrafenib and trametinib in metastatic pancreatic cancer.

scholarly journals More than Garden Variety: Massive Vegetations from Infective Endocarditis

Pathogens ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. 998
Author(s):  
Christopher Radcliffe ◽  
Joyce Oen-Hsiao ◽  
Matthew Grant
Keyword(s):  
Heart Failure ◽  
Infective Endocarditis ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Surgical Intervention ◽  
Case Reports ◽  
Source Control ◽  
Valvular Regurgitation ◽  
Vancomycin Therapy ◽  
Staphylococcus Aureus Bacteremia ◽  
History Of

Infective endocarditis classically involves non-sterile vegetations on valvular surfaces in the heart. Feared complications include embolization and acute heart failure. Surgical intervention achieves source control and alleviates valvular regurgitation in complicated cases. Vegetations >1 cm are often intervened upon, making massive vegetations uncommon in modern practice. We report the case of a 39-year-old female with history of intravenous drug abuse who presented with a serpiginous vegetation on the native tricuspid valve and methicillin-resistant Staphylococcus aureus bacteremia. The vegetation grew to 5.6 cm by hospital day two, and she successfully underwent a tricuspid valvectomy. Six weeks of intravenous vancomycin therapy were completed without adverse events. To better characterize other dramatic presentations of infective endocarditis, we performed a systematic literature review and summarized all case reports involving ≥4 cm vegetations.

scholarly journals Carcinosarcoma of the Bladder: A Case Report and Review of the Literature

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Doğan Atılgan ◽  
Yusuf Gençten
Keyword(s):  
Case Report ◽  
Urinary Bladder ◽  
Transurethral Resection ◽  
Tumor Recurrence ◽  
Case Reports ◽  
Sarcomatoid Carcinoma ◽  
Review Of The Literature ◽  
Biological Behaviour ◽  
Small Series ◽  
History Of

Carcinosarcoma of the urinary bladder is a rare neoplasm that is composed of malignant epithelial and mesenchymal components. In these tumors, histogenesis and biological behaviour remain controversial. Approximately 70 cases have been reported in the literature, usually as case reports or a small series. A series of 221 cases using the Surveillance, Epidemiology and End Results (SEER) Program database has been reported recently. Optimal treatment is uncertain. Herein, we report a case of sarcomatoid carcinoma of urinary bladder of a farmer aged 84 years old with a year history of hematuria and dysuria. A transurethral resection of the tumor (TUR-T) revealed a carcinosarcoma. The patient underwent radical cystectomy, and there is no tumor recurrence for 15 months after treatments.

Tumefactive fibroinflammatory lesion of the frontal sinus

2010 ◽  
Vol 124 (11) ◽  
pp. 1212-1215 ◽  
Author(s):  
C M Philpott ◽  
A R Javer
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Frontal Sinus ◽  
Surgical Intervention ◽  
Systemic Steroid ◽  
Review Of The Literature ◽  
Systemic Steroid Therapy ◽  
History Of ◽  
New Location ◽  
Tumefactive Fibroinflammatory Lesion

AbstractObjective:A 65-year-old man presented with a nine-month history of swelling in the midline of the forehead. After surgical intervention, this lesion was found to be a tumefactive fibroinflammatory lesion of the frontal sinus. This case report and review aims to report this new location for tumefactive fibroinflammatory lesion, and to discuss whether, in retrospect, there would have been alternative options to surgery.Methods:Case report and literature review.Results:Tumefactive fibroinflammatory lesions are rare. Although cases in the sinonasal tract have been described, none involving the frontal sinus have previously been reported. A review of the literature suggests that these lesions have an association with other fibroinflammatory lesions, and may be amenable to systemic steroid therapy.Conclusion:Each case should be managed on its merits, and a biopsy taken followed by subsequent screening for associated fibroinflammatory lesions. In the case of an isolated lesion, a surgical approach is probably favoured in a patient suitable for general anaesthesia.

Clear Cell Adenocarcinoma of the Cervix in a Child without in Utero Exposure to Diethylstilbestrol: A Case Report and Review of the Literature

2005 ◽  
Vol 8 (6) ◽  
pp. 690-695 ◽  
Author(s):  
William A. Ahrens ◽  
L. Patricia Barrón-Rodriguez ◽  
Millisa McKee ◽  
Scott Rivkees ◽  
Miguel Reyes-Múgica
Keyword(s):  
Differential Diagnosis ◽  
Clear Cell ◽  
Clinical History ◽  
In Utero ◽  
Embryonal Rhabdomyosarcoma ◽  
In Utero Exposure ◽  
Clear Cell Adenocarcinoma ◽  
Review Of The Literature ◽  
Cervical Tumor ◽  
History Of

We describe the case of a primary cervical tumor in a 6-year-old child that was originally suspected to be an embryonal rhabdomyosarcoma botryoides. Histologic analysis revealed a clear cell adenocarcinoma. Despite a direct search and questioning for maternal exposure to diethylstilbestrol, this was not documented. Clear cell adenocarcinoma is an extremely rare neoplasm that should be kept in the differential diagnosis of cervicovaginal lesions in children, even in the absence of a clinical history of in utero diethylstilbestrol exposure. We discuss the hypothesized pathogenesis and review the literature on this unusual tumor.

Verruciform Xanthoma of the Esophagus: Two Case Reports With Review of the Literature

2019 ◽  
Vol 28 (3) ◽  
pp. 302-305
Author(s):  
Hirotsugu Noguchi ◽  
Ikumi Kitazono ◽  
Kazumasa Hamada ◽  
Takako Tanaka ◽  
Takashi Tasaki ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Helicobacter Pylori ◽  
Case Reports ◽  
Fundic Gland ◽  
Epithelial Hyperplasia ◽  
Review Of The Literature ◽  
Fundic Gland Polyp ◽  
Verruciform Xanthoma ◽  
Elevated Lesion ◽  
History Of

Verruciform xanthoma is a rare benign verrucopapillary lesion that develops in the oral mucosa and genital skin. Its development in the esophagus is extremely rare, with only 5 reported cases. We present 2 cases of verruciform xanthoma of the esophagus. Case 1 involved a 91-year-old woman, who had hypertension and chronic gastritis with Helicobacter pylori infection, with a 12-year history of a 10-mm white-yellow elevated lesion on the esophagus, 35 cm from the incisor teeth. Case 2 involved a 70-year-old man with fundic gland polyp, hyperlipidemia, and lung cancer, who had a 10-mm whitish granular/verrucoid lesion on the esophagus, 28 cm from the incisor teeth. Microscopically, these lesions show verrucous and papillomatous epithelial hyperplasia with neutrophilic intraepithelial exocytosis. The histological hallmark is the presence of numerous foamy histiocytes infiltrating the elongated squamous epithelial papillae. Although its etiology is unknown, irritation or trauma caused by radiotherapy has been suggested.

Open and endovascular repair of hepatic artery aneurysm: two case reports and review of the literature

Vascular ◽  
2011 ◽  
Vol 19 (1) ◽  
pp. 42-46 ◽  
Author(s):  
Derek P Nathan ◽  
Grace J Wang ◽  
Edward Y Woo ◽  
Ronald M Fairman ◽  
Benjamin M Jackson
Keyword(s):  
Hepatic Artery ◽  
Endovascular Repair ◽  
Case Reports ◽  
Disease Process ◽  
Artery Aneurysm ◽  
Exploratory Laparotomy ◽  
Review Of The Literature ◽  
Hepatic Artery Aneurysm ◽  
History Of ◽  
Bifurcated Graft

Hepatic artery aneurysms (HAAs) represent a complex and often lethal condition. An 80-year-old woman with polyarteritis nodosa and a right hepatic lobe HAA underwent endovascular repair with coils. Her case was complicated by intraoperative HAA rupture requiring exploratory laparotomy. In the second case, a 37-year-old man with a large HAA underwent open repair with a bifurcated graft that extended from the common hepatic artery to the left and right hepatic arteries. These two cases highlight the difficulty of managing HAAs, and provide insight into their treatment. Furthermore, our review of the literature highlights the data on the management of HAAs, including the natural history of this disease process, the indications for repair and the optimal treatment modality.

scholarly journals Xanthogranulomatous Salpingitis Associated with a Large Uterine Leiomyoma

2010 ◽  
Vol 2010 ◽  
pp. 1-3 ◽  
Author(s):  
Joanne Margaret Howey ◽  
Etienne Mahe ◽  
Jasim Radhi
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Chronic Inflammation ◽  
Inflammatory Disease ◽  
Uterine Leiomyoma ◽  
Plasma Cells ◽  
Clinical History ◽  
Review Of The Literature ◽  
Xanthogranulomatous Inflammation ◽  
Exact Etiology ◽  
History Of

A case of xanthogranulomatous salpingitis (XGS) associated with a large uterine leiomyoma in a 50-year-old woman is presented. Xanthogranulomatous inflammation is an uncommon form of chronic inflammation that is destructive to affected organs. It is characterized by the presence of lipid-filled macrophages with admixed lymphocytes, plasma cells, and neutrophils. A review of the literature revealed that most patients with XGS have a clinical history of long-standing pelvic inflammatory disease (PID) or, less often, endometriosis. We report a case lacking a history of either PID or endometriosis but with a concurrent large uterine leiomyoma. Although the exact etiology in this case was not clear, the leiomyoma may have played a contributory role in pathogenesis.

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