scholarly journals A Meta-Analysis of Choroidal Thickness Changes in Unilateral Amblyopia

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Yanli Liu ◽  
Yi Dong ◽  
Kanxing Zhao
Keyword(s):  
Choroidal Thickness ◽  
Primary Outcome ◽  
Weighted Mean Difference ◽  
Meta Analysis ◽  
Enhanced Depth Imaging ◽  
Weighted Mean ◽  
Cross Sectional ◽  
Depth Imaging ◽  
Imaging Optical Coherence Tomography ◽  
And Control

Purpose. To date, the topic of amblyopic changes remains controversial. Therefore, a systematic review and meta-analysis were carried out to evaluate choroidal changes in unilateral amblyopia. Methods. Major literature databases were searched for amblyopia-relevant studies. Using enhanced depth imaging optical coherence tomography (EDI-OCT), the primary outcome parameters examined were subfoveal choroidal thickness (SFCT) and different choroidal thickness (CT) positions. Efficacy estimates were evaluated by weighted mean difference (WMD) and 95% confidence interval (CI) for choroidal-associated changes. We performed subgroup analysis and metaregression analysis to examine potential sources of heterogeneity. Results. Eleven cross-sectional studies that included a total of 768 participants were identified. The amblyopic eye SFCT was thicker than that of the fellow and control (normal) eyes (WMDamblyopia versus fellow=49.24, 95% CI of 30.22 to 68.27, p<0.001; WMDamblyopia versus control=54.51, 95% CI of 32.17 to 76.85, p<0.001). There were no differences between the fellow and control eyes (WMD=13.81, 95% CI of 1.16 to 28.77, p=0.071). Subgroup and metaregression analyses indicated that the OCT type was the main source of heterogeneity. Conclusions. The CT in the amblyopic eyes was thicker than that in the fellow and control eyes.

Measurement of Subfoveal Choroidal Thickness in Pseudoexfoliation Syndrome Using Enhanced Depth Imaging Optical Coherence Tomography

2015 ◽  
Vol 233 (3-4) ◽  
pp. 204-208 ◽  
Author(s):  
Ece Turan-Vural ◽  
Nursal Yenerel ◽  
Murat Okutucu ◽  
Elvin Yildiz ◽  
Nejla Dikmen
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Optical Coherence Tomography ◽  
Choroidal Thickness ◽  
Enhanced Depth Imaging ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Depth Imaging ◽  
Subfoveal Choroidal Thickness ◽  
Imaging Optical Coherence Tomography

Background/Aim: Pseudoexfoliation (PSX) syndrome is associated with blood flow disturbances; however, its exact effect on choroidal blood flow and thickness remains to be elucidated. This study compared subfoveal choroidal thickness in normal eyes and in eyes with PSX using enhanced depth imaging optical coherence tomography (EDI-OCT). Methods: This prospective, cross-sectional study included 35 eyes of 35 patients (20 males, 15 females) with unilateral or bilateral PSX and 26 eyes of 26 healthy volunteers (13 males, 13 females). Besides a comprehensive ocular and physical examination, all subjects underwent EDI-OCT examination using an Optovue RTVue OCT device (Optovue Inc., Fremont, Calif., USA). Results: The mean choroidal thickness (CT) and ocular perfusion pressure (OPP) were lower in the PSX group than in the healthy controls (249.4 ± 46.3 vs. 282.5 ± 55.8 µm, p = 0.014 and 40.7 ± 5.8 vs. 44.3 ± 4.3 mm Hg, p = 0.007, respectively). In addition, both systolic blood pressure and diastolic blood pressure measurements were lower among the PSX patients. However, no correlation was found between CT and OPP. Conclusion: The findings of this study suggest that PSX is associated with an overall thinning of the subfoveal choroid and a significant decrease in OPP. Future studies are warranted to further examine these relations.

scholarly journals Changes of Subfoveal Choroidal Thickness after Cataract Surgery: A Meta-Analysis

2018 ◽  
Vol 2018 ◽  
pp. 1-16 ◽  
Author(s):  
Shaoxue Zeng ◽  
Chen Liang ◽  
Yueqing He ◽  
Yingying Chen ◽  
Qing Zhao ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Choroidal Thickness ◽  
Meta Analysis ◽  
Enhanced Depth Imaging ◽  
Diabetic Mellitus ◽  
Depth Imaging ◽  
Before And After ◽  
Imaging Optical Coherence Tomography ◽  
Inflammatory Drugs ◽  
Thickness Measurements

Purpose. To investigate the effect of cataract surgery on subfoveal choroid thickness (SFCT) using enhanced-depth imaging optical coherence tomography (EDI-OCT). Materials and Methods. Relevant publications were searched systematically through various databases from inception to March 2018. The unit of choroidal thickness measurements is micrometers. Studies comparing SFCT before and after cataract surgery were retrieved. All qualified articles were analyzed using RevMan 5.3. Results. A total of 13 studies with 802 eyes from 646 patients were identified for inclusion. There was a significant increase of SFCT at 1 week (MD = 6.62, 95% CI: 1.20–12.05, P=0.02, I2 = 0%), 1 month (MD = 8.30, 95% CI: 3.20–13.39, P=0.001, I2 = 0%), and 3 months (MD = 8.28, 95% CI: 1.84–14.73, P=0.01, I2 = 0%) after cataract surgery. In subgroup analysis, SFCT in Asians and patients without nonsteroidal anti-inflammatory drugs (NSAIDs) in postoperative medication was significantly thicker (P<0.05). No statistically significant increase of SFCT was found in diabetic mellitus (DM) patients for 1 day (P=0.89), 1 week (P=0.59), 1 month (P=0.52), and 3 months (P=0.42) after cataract surgery. Conclusions. This meta-analysis suggested that SFCT increased since 1 week after the cataract surgery and the increase lasted for at least 3 months. Asians and patients without NSAIDs in postoperative medication were more likely to have a thicker SFCT after cataract surgery, whereas DM patients were less likely to increase in SFCT.

scholarly journals Choroidal thickness in eyes with different degrees of myopia

2013 ◽  
Vol 6 (4) ◽  
pp. 34-38 ◽  
Author(s):  
Yuriy Sergeyevich Astakhov ◽  
Svetlana Georgiyevna Belekhova
Keyword(s):  
Optical Coherence Tomography ◽  
Negative Correlation ◽  
Choroidal Thickness ◽  
Healthy People ◽  
Enhanced Depth Imaging ◽  
Control Group ◽  
Depth Imaging ◽  
Subfoveal Choroidal Thickness ◽  
Imaging Optical Coherence Tomography ◽  
Spectralis Oct

66 healthy people (124 eyes) with different degrees of myopia and emmetropia were examined using enhanced depth imaging optical coherence tomography (EDI-OCT) using the “Spectralis OCT”. It was found that the choroid in subjects with medium and high degrees of myopia was significantly thinner than that in the control group. In the study, a negative correlation was found between the subfoveal choroidal thickness and the degree of myopia (r = -0.75, p < 0.0001). It was also found that the subfoveal choroidal thickness decreased for each diopter of myopia by approximately 18.03 μm.

scholarly journals Analysis of Peripapillary and Macular Choroidal Thickness in Eyes with Pseudoexfoliative Glaucoma and Fellow Eyes

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Fan Li ◽  
Qingli Shang ◽  
Guangxian Tang ◽  
Hengli Zhang ◽  
Xiaowei Yan ◽  
...  
Keyword(s):  
Choroidal Thickness ◽  
Enhanced Depth Imaging ◽  
Average Volume ◽  
Depth Imaging ◽  
Pseudoexfoliative Glaucoma ◽  
Group A ◽  
Imaging Optical Coherence Tomography ◽  
Group B ◽  
Control Study ◽  
Fellow Eyes

Purpose. To compare differences in peripapillary and macular choroidal thickness in pseudoexfoliative glaucoma (PXG) eyes, nonexfoliative fellow eyes, and normal eyes. Methods. This case-control study included 37 PXG patients (group A: 37 PXG eyes; group B: 37 nonexfoliative fellow eyes) and 37 sex-, age-, and axial length-matched healthy volunteer eyes (group C). Peripapillary and macular choroidal thickness and volume were measured in all subjects via enhanced-depth imaging-optical coherence tomography. Results. The average peripapillary (AP) choroidal thickness was (130.10 ± 46.14) μm, (131.43 ± 46.00) μm, and (147.89 ± 53.32) μm; average macular (AM) choroidal thickness was (191.72 ± 68.07) μm, (204.62 ± 69.54) μm, and (215.10 ± 45.40) μm; and average volume was (0.59 ± 0.21) μm3, (0.63 ± 0.21) μm3, and (0.65 ± 0.14) μm3 in groups A, B, and C, respectively. NIP choroidal thickness was significantly lower in groups A and B than in group C (P<0.05). TIM and TOM choroidal thickness and volume were significantly lower in group A than in group C (P<0.05). NIM, SIM, NOM, IOM, AM choroidal thickness and volume, and CSM choroidal thickness were significantly lower in group A than in group B (P<0.05). CSM, TIM, and TOM in group A and TIM, TOM choroidal thickness, and volume in group B were significantly lower than in group C (P<0.05). Conclusions. NIP choroidal thickness in PXG eyes and nonexfoliative fellow eyes and temporal macular choroidal thickness in PXG eyes were significantly lower than in normal eyes. Macular choroidal thickness (except in temporal regions) was significantly lower in PXG eyes than in nonexfoliative fellow eyes. Changes in peripapillary and macula choroidal thickness further elucidate the choroid’s role in PXG development and progression.

Choroidal thickness evaluation in paediatric patients with adenotonsillar hypertrophy

2017 ◽  
Vol 131 (9) ◽  
pp. 768-772
Author(s):  
A Yenigun ◽  
A Elbay ◽  
A M Hafiz ◽  
O Ozturan
Keyword(s):  
Choroidal Thickness ◽  
Enhanced Depth Imaging ◽  
Control Group ◽  
Healthy Children ◽  
Depth Imaging ◽  
Adenotonsillar Hypertrophy ◽  
Paediatric Patients ◽  
Healthy Control ◽  
Imaging Optical Coherence Tomography ◽  
Thickness Measurements

AbstractObjective:To investigate choroidal thickness using enhanced-depth imaging optical coherence tomography in paediatric patients with adenotonsillar hypertrophy, with comparison to healthy children, three months after adenotonsillectomy.Methods:The patients were assigned to three groups: an adenotonsillar hypertrophy group, an adenotonsillectomy group and a healthy control group. In all groups, subfoveal, temporal and nasal choroidal thickness measurements were taken.Results:In the subfoveal, temporal and nasal regions, choroidal tissue was found to be significantly thinner in adenotonsillar hypertrophy children than healthy children (p = 0.012, p = 0.027 and p = 0.020). The subfoveal and temporal choroidal thickness measurements of adenotonsillar hypertrophy group cases were significantly decreased compared to those in the adenotonsillectomy group (p = 0.038 and p = 0.048).Conclusion:There was a significant association between decreased choroidal thickness and adenotonsillar hypertrophy. Adenotonsillar hypertrophy may play an important role in decreased choroidal thickness.

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