scholarly journals Cognitive Impairment in Chronic Kidney Disease: Vascular Milieu and the Potential Therapeutic Role of Exercise

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Ulf G. Bronas ◽  
Houry Puzantian ◽  
Mary Hannan
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Cognitive Impairment ◽  
Kidney Disease ◽  
Physical Function ◽  
Vascular Dysfunction ◽  
Therapeutic Modality ◽  
Increased Risk

Chronic kidney disease (CKD) is considered a model of accelerated aging. More specifically, CKD leads to reduced physical functioning and increased frailty, increased vascular dysfunction, vascular calcification and arterial stiffness, high levels of systemic inflammation, and oxidative stress, as well as increased cognitive impairment. Increasing evidence suggests that the cognitive impairment associated with CKD may be related to cerebral small vessel disease and overall impairment in white matter integrity. The triad of poor physical function, vascular dysfunction, and cognitive impairment places patients living with CKD at an increased risk for loss of independence, poor health-related quality of life, morbidity, and mortality. The purpose of this review is to discuss the available evidence of cerebrovascular-renal axis and its interconnection with early and accelerated cognitive impairment in patients with CKD and the plausible role of exercise as a therapeutic modality. Understanding the cerebrovascular-renal axis pathophysiological link and its interconnection with physical function is important for clinicians in order to minimize the risk of loss of independence and improve quality of life in patients with CKD.

scholarly journals Helping people to live well with chronic kidney disease

2020 ◽  
Vol 81 (6) ◽  
pp. 1-10 ◽  
Author(s):  
Simon Fraser ◽  
Maarten Taal
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Treatment Burden ◽  
Pharmacological Interventions ◽  
Increased Risk ◽  
Future Risk ◽  
Poor Outcomes

Reduced glomerular filtration rate and presence of albuminuria are both associated with increased risk of several poor outcomes. People with chronic kidney disease also commonly suffer from lower quality of life than their age-matched peers. The experiences reported by patients with chronic kidney disease include being shocked by the diagnosis, being uncertain about the cause and worrying about progression and future treatment. Issues such as depression, pain and fatigue are common in people with chronic kidney disease. Helping people to live well with a long-term condition like chronic kidney disease should include efforts to reduce the risk of adverse events occurring in the future, and consider what can be done to enhance quality of life now. Clinicians can help by being aware of the patient perspective, communicating clearly and recommending interventions that reduce future risk as well as recognising and treating symptoms. Assessing overall treatment burden is an important component of management and non-pharmacological interventions that may improve mobility, strength and pain should be considered.

scholarly journals Personality, Coping Strategy, and Quality of Life of Patients with Chronic Kidney Disease

2021 ◽  
Vol 48 (3) ◽  
pp. 199
Author(s):  
Evlijn Pasha Widjast ◽  
Magdalena S Halim
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Coping Strategies ◽  
Psychological Intervention ◽  
Neo Personality Inventory ◽  
Stress Symptoms ◽  
Neo Personality Inventory Revised

Patients with chronic kidney disease are subject to prolonged medical treatment that might affect their quality of life. The purpose of this research was to investigate the correlation between personality, coping strategies, and quality of life in patients with chronic kidney disease. 40 Participants (25-55 years old) were recruited using purposive sampling and presented with three instruments: the Indonesian versions of NEO Personality Inventory-Revised (NEO PI-R), Ways of Copings, and Kidney Disease Quality of Life-36 (KDQOL-36). Results showed a significant correlation between all variables after regression analysis was applied. Further results indicate certain coping strategies were related to an individual’s perceptions of kidney disease. A significant correlation was found between three personality traits: neuroticism, extraversion and conscientiousness, and quality of life. Results also found that female patients have a better quality of life than men. Further research is needed to examine further the crucial role of social support and ethnic differences. Psychological intervention programs to provide psychoeducation on how to recognize stress symptoms and better stress management for patients with chronic kidney disease are also warranted.

9. Effects of neuropathy on physical function and quality of life in moderate severity chronic kidney disease

2014 ◽  
Vol 125 (4) ◽  
pp. e4 ◽  
Author(s):  
Ria Arnold ◽  
Natalie Kwai ◽  
Bruce A. Pussell ◽  
Cindy S.-Y. Lin ◽  
Matthew C. Kiernan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Physical Function ◽  
Moderate Severity

scholarly journals A Randomized Double-Blind Cross-Over Trial to Study the Effects of Resistant Starch Prebiotic in Chronic Kidney Disease (ReSPECKD)

2021 ◽  
Author(s):  
Maryam Shamloo ◽  
Rebecca Mollard ◽  
Haizhou Wang ◽  
Kulwant Kingra ◽  
Navdeep Tangri ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Gut Microbiome ◽  
Resistant Starch ◽  
Potato Starch ◽  
Uremic Toxins ◽  
Double Blind ◽  
Increased Risk

Abstract Background: Chronic kidney disease (CKD) is associated with a reduced quality of life and an increased risk of kidney failure, cardiovascular events, and all-cause mortality. Accumulation of nitrogen-based uremic toxins leads to worsening of symptoms in individuals with CKD. Many uremic toxins, such as indoxyl and p-cresol sulphate, are produced exclusively by the gut microbiome through the proteolytic digestion of aromatic amino acids. Strategies to reduce the production of these toxins by the gut microbiome in individuals with CKD may lessen symptom burden and delay the onset of dialysis. One such strategy is to change the overall metabolism of the gut microbiome so that less uremic toxins are produced. This can be accomplished by manipulating the energy source available to the microbiome. Fermentable carbohydrates which reach the gut microbiome, like resistant starch (RS), have been shown to inhibit or reduce bacterial amino acid metabolism. This study aims to investigate the the effects of resistant potato starch (RPS) as a prebiotic in individuals with CKD before the onset of dialysis. Methods: This is a double blind, randomized two-period crossover trial. 36 eligible participants will consent to follow a 26-week study regimen. Participants will receive 2 sachets per day containing either 15 grams of RPS (MSPrebiotic, resistant potato starch treatment) or 15 grams corn starch (Amioca TF, digestible starch control). Changes in blood uremic toxins will be investigated as the primary outcome. Secondary outcomes include the effect of RPS consumption on symptoms, quality of life and the abundance, diversity and functionality of the gut microbiome.Discussion: This pilot randomized trial will provide further insight into whether the consumption of RPS as a prebiotic will reduce uremic toxins and symptoms in individuals who have CKD. Trial registration: NCT04961164

scholarly journals The Role of Personality and Social Support in Health-Related Quality of Life in Chronic Kidney Disease Patients

PLoS ONE ◽  
2015 ◽  
Vol 10 (7) ◽  
pp. e0129015 ◽  
Author(s):  
Norhayati Ibrahim ◽  
Sharlene S. L. Teo ◽  
Normah Che Din ◽  
Abdul Halim Abdul Gafor ◽  
Rozmi Ismail
Keyword(s):  
Quality Of Life ◽  
Social Support ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals A Personalized Multi-Component Lifestyle Intervention Program Leads to Improved Quality of Life in Persons with Chronic Kidney Disease

2019 ◽  
Author(s):  
Samuel A. Headley ◽  
Jasmin C. Hutchinson ◽  
Brian A. Thompson ◽  
Marissa L. Ostroff ◽  
Courtney J. Doyle-Campbell ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Health Outcomes ◽  
Physical Function ◽  
Lifestyle Intervention ◽  
Intervention Group ◽  
Self Report ◽  
Care Group

AbstractIntroductionLifestyle interventions have been shown to produce favorable changes in some health outcomes in patients with chronic kidney disease (CKD). However, few such studies, employing “real world” methods have been completed in patients with CKD.ObjectiveThis study tested the effectiveness of a comprehensive, multicomponent, lifestyle intervention, delivered through individualized counseling on a variety of health outcomes in pre-dialysis CKD patients.MethodsEligible patients were assigned randomly to the intervention (TR) or usual care group (UC). A six-month home-based program involving personalized counseling to increase physical activity to recommended levels among stage G3a to G4 CKD patients while exchanging plant proteins for animal proteins was implemented. Physical function, cardiovascular function, dietary intake, medication use, and health-related quality of life (HRQOL) were assessed at baseline and after 1-month, 3-months (M3) and 6-months (M6).ResultsForty-two, patients (age 60.2 ± 9.2, BMI 34.5 ± 7.8) participated in this study (TR=27 UC=15). The intervention reduced (p<0.05) brachial (bSBP) and central systolic blood pressures (cSBP) at month 3 (M3) but both were attenuated at month 6 (M6). Scores on the effect of kidney disease subscale of the HRQOL measure improved in the intervention group at M3 and M6. There was no change in the other measures of HRQOL or in any physical function scores.ConclusionsThis personalized multi-component lifestyle intervention enabled CKD patients to self-report fewer concerns with how CKD affected their daily lives independent of changes in physical function.

Cognitive impairment, quality of life and healthcare utilization in patients with chronic kidney disease stages 3 to 5

Nephrology ◽  
2020 ◽  
Vol 25 (8) ◽  
pp. 625-633 ◽  
Author(s):  
Onnita Thancharoen ◽  
Onanong Waleekhachonloet ◽  
Chulaporn Limwattananon ◽  
Sirirat Anutrakulchai
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Cognitive Impairment ◽  
Kidney Disease ◽  
Healthcare Utilization ◽  
Disease Stages

HUBUNGAN EFIKASI DIRI DENGAN KUALITAS HIDUP PASIEN GAGAL GINJAL KRONIK YANG MENJALANI HEMODIALISIS

2018 ◽  
Vol 5 (2) ◽  
pp. 56-63
Author(s):  
Abdul Wakhid ◽  
Estri Linda Wijayanti ◽  
Liyanovitasari Liyanovitasari
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Self Efficacy ◽  
Healing Process ◽  
Sampling Technique ◽  
P Value ◽  
Cross Sectional ◽  
Kolmogorov Smirnov

Background: Self efficacy can optimize the quality of life of clients who undergo the healing process due to chronic diseases. Individuals with higher self-efficacy move their personal and social resources proactively to maintain and improve the quality and length of their lives so that they experience a better quality of life. Objectives: the purpose of this study was to find the correlation between self efficacy and quality of life of patients with chronic kidney disease who undergo hemodialysis at RSUD Semarang Regency. Metode: This type of research was descriptive correlation with cross sectional approach. The samples in this study more 76 people with total sampling technique. The data collection tool for self efficacy was measured by General Self-Efficacy scale, for quality of life with WHOQoL-BREF. Statistical test used Kolmogorov-smirnov. Result: The result showed that self efficacy in patients with chronic kidney disease was mostly in moderate category (53,9%), quality of life in patients with chronic kidney disease was mostly in good category (68,4%). There was a correlation between self efficacy and quality of life of patients with chronic kidney disease who undergo hemodialysis at RSUD Semarang Regency, the result obtained p-value of 0.000 <α (0,05). Suggestion: Patients with chronic kidney disease can maintain good quality of life by helping to generate positive self-esteem and high self efficacy.

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