scholarly journals Myelopathy due to Spinal Extramedullary Hematopoiesis in a Patient with Polycythemia Vera

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Shuhei Ito ◽  
Nobuyuki Fujita ◽  
Naobumi Hosogane ◽  
Narihito Nagoshi ◽  
Mitsuru Yagi ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Effective Treatment ◽  
Polycythemia Vera ◽  
Spinal Cord Compression ◽  
Epidural Space ◽  
Operative Therapy ◽  
Extramedullary Hematopoiesis ◽  
Cord Compression ◽  
Hematological Disorders ◽  
Spinal Epidural

Extramedullary hematopoiesis (EMH) occasionally occurs in patients exhibiting hematological disorders with decreased hematopoietic efficacy. EMH is rarely observed in the spinal epidural space and patients are usually asymptomatic. In particular, in the patients with polycythemia vera, spinal cord compression due to EMH is extremely rare. We report a case of polycythemia vera, in which operative therapy proved to be an effective treatment for myelopathy caused by spinal EMH.

The pathogenesis of spinal epidural abscess: microangiographic studies in an experimental model

1988 ◽  
Vol 69 (1) ◽  
pp. 110-114 ◽  
Author(s):  
John A. Feldenzer ◽  
Paul E. McKeever ◽  
Dennis R. Schaberg ◽  
John A. Campbell ◽  
Julian T. Hoff
Keyword(s):  
Spinal Cord ◽  
Experimental Model ◽  
Spinal Cord Compression ◽  
Epidural Space ◽  
Epidural Abscess ◽  
Vascular Anatomy ◽  
Cord Compression ◽  
Spinal Epidural Abscess ◽  
Content Type ◽  
Spinal Epidural

✓ An experimental model of spinal epidural abscess was developed in rabbits by injecting Staphylococcus aureus into the posterior thoracolumbar epidural space. This model has been shown to reproduce the neurological, bacteriological, and radiological aspects of the human disease. In this study, the effect of the infectious epidural mass on the vasculature of the spinal cord in paraplegic rabbits was studied using microangiographic techniques. The normal vascular anatomy of the rabbit spinal cord was defined in control experiments. Vascular proliferation was demonstrated in the epidural space surrounding the abscesses. Anterior and paired posterior spinal arteries remained patent in paraplegic rabbits with mild or moderate spinal cord compression and in some cases of severe compression. In animals with severe compression, the anterior epidural venous plexus remained patent, but the dorsal spinal vein was occluded. Occlusion of perforating arteries occurred only with extreme spinal cord compression. These data indicate that the initial neurological deficit associated with experimental spinal epidural abscess is not due to vascular thrombosis.

scholarly journals Spinal cord compression due to extramedullary hematopoiesis in polycythemia vera

2003 ◽  
Vol 73 (4) ◽  
pp. 297-298 ◽  
Author(s):  
Tania Nicole Masmas ◽  
Eva Charlotte Jacobsen ◽  
Lone Rasch ◽  
Anders Krarup-Hansen ◽  
Henrik Birgens
Keyword(s):  
Spinal Cord ◽  
Polycythemia Vera ◽  
Spinal Cord Compression ◽  
Extramedullary Hematopoiesis ◽  
Cord Compression

Spinal Cord Compression due to Extramedullary Hematopoiesis in the Proliferative Phase of Polycythemia vera

1996 ◽  
Vol 96 (4) ◽  
pp. 242-244 ◽  
Author(s):  
josé Carlos Oliveira de Morais ◽  
Nelson Spector ◽  
Fabíola Passeri Lavrado ◽  
Luis Felipe Nobre ◽  
James Pitágoras de Mattos ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Polycythemia Vera ◽  
Spinal Cord Compression ◽  
Extramedullary Hematopoiesis ◽  
Cord Compression ◽  
Proliferative Phase

Spinal cord compression due to extramedullary hematopoiesis in beta-thalassemia

2020 ◽  
Vol 78 (10) ◽  
pp. 663-664
Author(s):  
Renan Ramon Souza LOPES ◽  
Larissa Soares CARDOSO ◽  
Franz ONISHI
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Extramedullary Hematopoiesis ◽  
Cord Compression ◽  
Beta Thalassemia

scholarly journals Spontaneous Spinal Epidural Haematomas and the Prognostic Implications of Interval to Surgical Decompression: A Report of Two Cases

2009 ◽  
Vol 17 (2) ◽  
pp. 216-219 ◽  
Author(s):  
Colin Yi-Loong Woon ◽  
Benedict Chan-Wearn Peng ◽  
John Li-Tat Chen
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Lower Limb ◽  
Cord Compression ◽  
Surgical Decompression ◽  
Neurological Recovery ◽  
Uncontrolled Hypertension ◽  
Motor Deficit ◽  
Mri Features ◽  
Spinal Epidural

Spontaneous spinal epidural haematomas (SSEHs) are rare causes of spinal cord compression. We present 2 cases of thoracic SSEHs with similar magnetic resonance imaging (MRI) features. Patient 1 was on long-term oral anticoagulants and patient 2 had uncontrolled hypertension. Patient 1 presented with a dense motor deficit, whereas patient 2 developed progressive lower limb weakness. Decompression laminectomy and haematoma evacuation was performed 51 hours later for patient 1 and 14 hours later for patient 2. Both had recovered their lower limb power, but neurological recovery was greater for patient 2. In patients with bleeding diatheses or uncontrolled hypertension, acute SSEHs must be suspected when they present with atraumatic back pain and signs of spinal cord compression. The interval to surgical decompression greatly influences the prognosis for neurological recovery.

scholarly journals Spinal cord compression in b-thalassemia: follow-up after radiotherapy

1998 ◽  
Vol 116 (6) ◽  
pp. 1879-1881 ◽  
Author(s):  
Silvana Fahel da Fonseca ◽  
Maria Stella Figueiredo ◽  
Rodolfo Delfini Cançado ◽  
Fernando Nakandakare ◽  
Roberto Segreto ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Case Report ◽  
Spinal Cord Compression ◽  
Low Dose ◽  
Extramedullary Hematopoiesis ◽  
Cord Compression ◽  
Hematologic Disorders ◽  
Rare Syndrome ◽  
Low Dose Radiotherapy

CONTEXT: Spinal cord compression due to extramedullary hematopoiesis is a well-described but rare syndrome encountered in several clinical hematologic disorders, including <FONT FACE="Symbol">b</font>-thalassemia. CASE REPORT: We report the case of a patient with intermediate <FONT FACE="Symbol">b</font>-thalassemia and crural paraparesis due to spinal cord compression by a paravertebral extramedullary mass. She was successfully treated with low-dose radiotherapy and transfusions. After splenectomy, she was regularly followed up for over four years without transfusion or recurrence of spinal cord compression. DISCUSSION: Extramedullary hematopoiesis should be investigated in patients with hematologic disorders and spinal cord symptoms. The rapid recognition and treatment with radiotherapy can dramatically alleviate symptoms.

Painful Spinal Cord Compression as a Complication of Extramedullary Hematopoiesis Associated with β-Thalassemia Intermedia

2008 ◽  
Vol 184 (4) ◽  
pp. 224-226 ◽  
Author(s):  
Martin Goerner ◽  
Sabine Gerull ◽  
Erhard Schaefer ◽  
Marianne Just ◽  
Martin Sure ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Extramedullary Hematopoiesis ◽  
Cord Compression ◽  
Thalassemia Intermedia
Sign in / Sign up

Export Citation Format

Share Document