scholarly journals First-Trimester Crown-Rump Length and Embryonic Volume of Fetuses with Structural Congenital Abnormalities Measured in Virtual Reality: An Observational Study

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
L. Baken ◽  
B. Benoit ◽  
A. H. J. Koning ◽  
P. J. van der Spek ◽  
E. A. P. Steegers ◽  
...  

Background. With the introduction of three-dimensional (3D) ultrasound it has become possible to measure volumes. The relative increase in embryonic volume (EV) is much larger than that of the crown-rump length (CRL) over the same time period. We examined whether EV is a better parameter to determine growth restriction in fetuses with structural congenital abnormalities. Study Design, Subjects, and Outcome Measures. CRL and EV were measured using a Virtual Reality (VR) system in prospectively collected 3D ultrasound volumes of 56 fetuses diagnosed with structural congenital abnormalities in the first trimester of pregnancy (gestational age 7+5 to 14+5 weeks). Measured CRL and EV were converted to z-scores and to percentages of the expected mean using previously published reference curves of euploid fetuses. The one-sample t-test was performed to test significance. Results. The EV was smaller than expected for GA in fetuses with structural congenital abnormalities (−35%  p<0.001, z-score −1.44  p<0.001), whereas CRL was not (−6.43%  p=0.118, z-score −0.43  p=0.605). Conclusions. CRL is a less reliable parameter to determine growth restriction in fetuses with structural congenital abnormalities as compared with EV. By measuring EV, growth restriction in first-trimester fetuses with structural congenital abnormalities becomes more evident and enables an earlier detection of these cases.

2017 ◽  
Vol 45 (9) ◽  
Author(s):  
Haitham A. Torky ◽  
Asem A. Moussa ◽  
Ali M. Ahmad ◽  
Osama Dief ◽  
Manar A. Eldesoouky ◽  
...  

AbstractAim of work:To determine whether fetal volume (FV) measured by three-dimensional (3D) ultrasound was able to detect fetuses at risk of low birth weight (primary outcome) and/or preterm labor (secondary outcome).Methods:One hundred pregnant women carrying a singleton living pregnancy who were sure of dates, and had a dating scan, with gestational age between 11 weeks and 13 weeks+6 days coming for routine first trimester nuchal translucency (NT) were examined by both two-dimensional (2D) and 3D ultrasound (Vocal System) for crown-rump length (CRL) and FV then followed up regularly every 4 weeks until 28 weeks then biweekly until 36 weeks then weekly until delivery both clinically and by ultrasound biometry.Findings:Eighty-seven cases had a normal outcome, while the remaining 13 cases had either preterm labor (four cases) or low-birth weight (nine cases). FV positively correlated with CRL (P=0.026), gestational age in weeks (P=0.002), neonatal body weight in grams (P=0.018) and neonatal body length at birth (P=0.04). A mean FV of 8.3 mmConclusion:3D assessment of FV in the first trimester provides an accurate method for predicting pregnancy outcome namely low birth weight and neonatal complications, however, it is a better positive predictor than a negative one.


2021 ◽  
Vol 2021 ◽  
pp. 1-16
Author(s):  
Jing Li ◽  
Tao Hou

From the construction of “new socialist countryside” to the proposal of “full coverage of village planning,” rural construction has gradually been pushed to a climax. However, the current situation of rural landscape construction in China is not optimistic. On the one hand, the rural landscape deviates from its rural and regional characteristics due to deliberately seeking novelty and differences. Based on these two extreme development trends, this article uses virtual reality technology to construct a rural landscape virtual-roaming system, and randomly select 25 people, each group of 5 people, a total of 3 groups, enter the system in batches with a real reduction degree of 30%, 45%, 60%, 75%, and 80% for experimentation and score the system after the experience. The true reduction degree of the first group is 30%; the true reduction degree of the second group is 45%; the true reduction degree of the third group is 60%; the true reduction degree of the fourth group is 75%; and the true reduction degree of the fifth group is 80%. After analyzing the experimental data, it is concluded that when the true reduction degree of the system goes from low to high, people’s satisfaction is higher; when the true reduction degree is as high as 80%, the satisfaction is as high as 9 points; when the true reduction degree of the system goes from low to high, people’s sense of immersion is getting deeper and deeper. When the true reduction degree is 30%, the lowest score for immersion is 1 point; when the true reduction degree is 80%, the lowest score for immersion is 7.5 points; the true reduction of the system decreases from high to low; when it is high, people’s interaction degree becomes stronger and stronger. When the true reduction degree is 30%, the lowest interaction degree score is 2 points; when the true reduction degree is 80%, the lowest interaction degree score is 9 points; it can be seen from this that, with the increase in the degree of realism of the rural landscape virtual-roaming system, it is extremely difficult for people to find whether they are in the virtual or the reality, and their immersion in virtual reality is getting deeper and deeper. This test also confirmed the superiority of the virtual roaming system in rural landscapes, and the experience is extremely effective.


2014 ◽  
Vol 3 (2) ◽  
Author(s):  
Ozgur Ozyuncu ◽  
Mert Turgal ◽  
Aslihan Yazicioglu

AbstractDiastrophic dysplasia is a rare genetic disorder characterized by short limbs and deformities of several joints occurring in conjunction with xyphoscoliosis, distinctive abduction of the first metacarpals (hitchhiker thumbs). A 28-year-old pregnant patient was referred due to detection of increased nuchal translucency at the first-trimester scan. We describe a case of diastrophic dysplasia diagnosed by two- and three-dimensional ultrasound and termination of pregnancy at 13 weeks of gestation. This case is the first report in the literature in which 3D ultrasound was used in diagnosis of diastrophic dysplasia as early as the 13th week of pregnancy. We think that prenatal diagnosis of diastrophic dysplasia can be possible even at first trimester.


Lymphology ◽  
2019 ◽  
Vol 52 (1) ◽  
Author(s):  
D Paladini ◽  
G Donarini ◽  
A Conti ◽  
L Costanza De Angelis ◽  
MH Witte ◽  
...  

The aim of this study is to assess whether early cervical lymphatic obstruction is associated with a sonographically detectable dilatation of the ventricular system in the 1st trimester of pregnancy. In particular, the objective is to assess whether fetuses with non-immune hydrops fetalis (NIHF), cystic hygroma, or enlarged nuchal translucency (NT) have a greater atrial width/biparietal diameter (AW/BPD) ratio than normal at time of the combined first trimester screening scan. This retrospective study included 96 first trimester fetuses (33 normal and 63 with various degree of cervical lymphatic engorgement). Inclusion criteria were CRL in the 45-84 mm range and availability of one or more three-dimensional volume datasets of the fetal head, acquired from the BPD plane. Each three-dimensional volume dataset was opened and multiplanar correlation employed to align the three orthogonal planes. The ratio between the atrial width and the BPD (AW/BPD ratio) was used to evaluate the possible presence of increased amount of cerebrospinal fluid. Abnormal cases were placed into 4 categories: 1)enlarged non-septated NT 2.5-3.9 mm, no hydrops; 2) grossly enlarged non-septated NT/ edema &gt;3.9 mm; 3) cystic hygroma and/or NIHF; 4) major anomalies with NT &lt;2.5 mm. Presence of dilatation of the latero-cervical jugular lymphatic sacs, karyotype and presence of congenital anomalies were also recorded. The One-way ANOVA test was used to compare means. Intra- and inter-observer variability were also assessed. The AW/BPD ratio was found to be significantly higher in fetuses with grossly enlarged NT/nuchal edema and NIHF/septated cystic hygroma than in normal (p &lt;0.05 and p &lt;0.01, respectively). Also, the AW/BPD ratio was significantly higher in NIHF/septated cystic hygroma than in enlarged NT 2.5-3.9 mm (p &lt;0.05). In case of enlarged NT (2.5-3.9 mm), the AW/BPD ratio is significantly higher in presence of JLS (p &lt;0.01). At the end of the first trimester, presence of cervical lymphatic engorgement, in terms of grossly enlarged NT, nuchaledema, septated cystic hygroma, and NIHF, is statistically associated with a moderate dilatation of the ventricular system. Of note, among fetuses with moderately enlarged NT, those with evidence of dilatation of the JLS show a statistically significant increase in the AW/BPD ratio.


2019 ◽  
Vol 54 (S1) ◽  
pp. 318-318
Author(s):  
C. Pietersma ◽  
M. Rousian ◽  
A. Go ◽  
A. Mulders

Leonardo ◽  
2018 ◽  
Vol 51 (2) ◽  
pp. 124-127 ◽  
Author(s):  
Águeda Simó

Virtual reality systems are an ideal platform for exploring spatial effects because of their ability to combine stereo imaging techniques and interactive real-time graphics. They allow the creation of artworks that, on the one hand, exhibit a dynamic organization of the environment’s spatial depth and, on the other, create an interaction with the stereoscopic optic flow. In this article, the author discusses the advantages of horizontal stereoscopic displays and describes how she has used the Responsive Workbench to display the evolution of a flat land into a three-dimensional world in her artwork Endocytosis. She uses endocytosis—a fundamental cellular trafficking process that moves material into the intracellular space—as a metaphor for this evolutionary process.


ABSTRACT Transvaginal high-resolution ultrasound and three-dimensional (3D) ultrasound have been establishing sonoembryology as well as neurosonography in the first trimester. Fetal brain is rapidly developing and changing its appearance week by week during pregnancy. The most important organ, but it is quite hard to observe detailed structure of this organ by conventional transabdominal sonography. It is possible to observe the whole brain structure by magnetic resonance imaging in the post half of pregnancy, but it is difficult in the first half gestation, and transvaginal high-resolution 3D ultrasound is the most powerful modality. As for brain vascularization, main arteries and veins have been demonstrated and evaluated in various CNS conditions. Transvaginal high-resolution 3D ultrasound can demonstrate cerebral fine vascular anatomy, such as medullary vessels and it is greatly expected to estimate neurological prognosis relating with vascular development during fetal period.


2019 ◽  
Vol 8 (2) ◽  
Author(s):  
Reinhard Altmann ◽  
Christina Allerstorfer ◽  
Iris Scharnreitner ◽  
Wolfgang Arzt

Abstract Background This case report is to show the details of the face of a very rare ethmocephaly at 14 weeks of gestation. Case presentation After the regular transabdominal two-dimensional (2D) scan for nuchal translucency we could describe the following malformations: holoprosencephaly, proboscis and an abnormal face, omphalocele containing bowel, hyperechoic kidneys and megacystis. In addition, we acquired transvaginal three-dimensional (3D) ultrasound volume blocks of the fetal head, scanned with different insonation angles and stored them for later analysis. Using the multiplanar mode the volume blocks taken from the front show all details of the face: proboscis, hypotelorism, microphthalmia, cleft palate, accelerated development of the frontal bones and premature closure of the metopic suture. The volume blocks taken through the squamosal suture show all details of the fossa posterior and brain: fused thalami surrounded by the typical monoventricle, normal brain stem, elongation of anterior membranous area. Render mode shows a precise 3D image of the face. To better demonstrate the changes of the fetal face a post-mortem photo of the fetal face is included. Conclusion This case report can demonstarte the typical changes of ethmocephaly in the first trimester using transvaginal 3D scan.


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